CN109328230A - 嵌合同种异体抗原受体t细胞的组合物和方法 - Google Patents

嵌合同种异体抗原受体t细胞的组合物和方法 Download PDF

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Publication number
CN109328230A
CN109328230A CN201780036162.2A CN201780036162A CN109328230A CN 109328230 A CN109328230 A CN 109328230A CN 201780036162 A CN201780036162 A CN 201780036162A CN 109328230 A CN109328230 A CN 109328230A
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cell
acid sequence
nucleic acid
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gly
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M·C·米洛内
V·阿鲁达
S·里奇曼
B·萨梅尔森-琼斯
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Childrens Hospital of Philadelphia CHOP
University of Pennsylvania Penn
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University of Pennsylvania Penn
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CN201780036162.2A 2016-04-15 2017-04-14 嵌合同种异体抗原受体t细胞的组合物和方法 Pending CN109328230A (zh)

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US201662322937P 2016-04-15 2016-04-15
US62/322,937 2016-04-15
PCT/US2017/027754 WO2017181101A1 (en) 2016-04-15 2017-04-14 Compositions and methods of chimeric alloantigen receptor t cells

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US (2) US20190153064A1 (enExample)
EP (1) EP3443076A4 (enExample)
JP (3) JP2019513394A (enExample)
KR (1) KR20190003550A (enExample)
CN (1) CN109328230A (enExample)
AU (2) AU2017248817A1 (enExample)
CA (1) CA3020599A1 (enExample)
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Cited By (5)

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CN114127287A (zh) * 2019-05-13 2022-03-01 宾夕法尼亚大学董事会 乙酰胆碱受体嵌合自身抗体受体细胞的组合物和方法
WO2022083590A1 (zh) * 2020-10-19 2022-04-28 南京卡提医学科技有限公司 包含dap12和共刺激信号分子信号域的嵌合受体及其使用方法
CN114929747A (zh) * 2019-11-05 2022-08-19 詹森生物科技公司 多发性骨髓瘤的靶向bcma的car-t细胞疗法
CN115516086A (zh) * 2020-05-13 2022-12-23 南京传奇生物科技有限公司 类猿icp47及变体减少同种异体细胞宿主排斥的组合物及方法
CN116103239A (zh) * 2021-11-11 2023-05-12 南京北恒生物科技有限公司 工程化免疫细胞及其用途

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CN110903399B (zh) * 2018-09-17 2022-02-01 台湾中国医药大学附设医院 嵌合抗原受体、其核酸、表达质体、细胞、用途及组合物
AU2020272074A1 (en) * 2019-04-12 2021-11-25 The Trustees Of The University Of Pennsylvania Compositions and Methods Comprising a High Affinity Chimeric Antigen Receptor (CAR) with Cross-Reactivity to Clinically-Relevant EGFR Mutated Proteins
CN113646433B (zh) * 2020-07-16 2022-10-11 苏州博腾生物制药有限公司 靶向抗TNF-α抗体的组合物和方法
CN116157415A (zh) * 2020-09-03 2023-05-23 苏州博腾生物制药有限公司 靶向抗rh抗体的组合物和方法
CN114369168B (zh) * 2020-10-19 2024-08-30 南京卡提医学科技有限公司 包含dap12和共刺激信号分子信号域的嵌合受体及其使用方法
EP4611775A1 (en) * 2022-11-04 2025-09-10 The Children's Hospital Of Philadelphia Compositions and methods for b cell directed immunotherapies for anti-aav neutralizing alloantibodies

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