RU2018130994A3 - - Google Patents

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Publication number
RU2018130994A3
RU2018130994A3 RU2018130994A RU2018130994A RU2018130994A3 RU 2018130994 A3 RU2018130994 A3 RU 2018130994A3 RU 2018130994 A RU2018130994 A RU 2018130994A RU 2018130994 A RU2018130994 A RU 2018130994A RU 2018130994 A3 RU2018130994 A3 RU 2018130994A3
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RU
Russia
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RU2018130994A
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RU2731615C2 (ru
RU2018130994A (ru
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Publication of RU2018130994A3 publication Critical patent/RU2018130994A3/ru
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839Polyphosphonic acids
    • C07F9/386Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839Polyphosphonic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839Polyphosphonic acids
    • C07F9/3843Polyphosphonic acids containing no further substituents than -PO3H2 groups
    • C07F9/3852Cycloaliphatic derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839Polyphosphonic acids
    • C07F9/3856Polyphosphonic acids containing halogen or nitro(so) substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839Polyphosphonic acids
    • C07F9/3865Polyphosphonic acids containing sulfur substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2018130994A 2016-01-29 2017-01-27 Новое соединение бисфосфоновой кислоты RU2731615C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2016-027405 2016-01-29
JP2016027405 2016-01-29
PCT/JP2017/002855 WO2017131127A1 (ja) 2016-01-29 2017-01-27 新規ビスホスホン酸化合物

Publications (3)

Publication Number Publication Date
RU2018130994A RU2018130994A (ru) 2020-03-03
RU2018130994A3 true RU2018130994A3 (ru) 2020-03-13
RU2731615C2 RU2731615C2 (ru) 2020-09-07

Family

ID=59398507

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018130994A RU2731615C2 (ru) 2016-01-29 2017-01-27 Новое соединение бисфосфоновой кислоты

Country Status (19)

Country Link
US (1) US10689408B2 (ru)
EP (1) EP3409679A4 (ru)
JP (1) JP6259957B2 (ru)
KR (1) KR20180111791A (ru)
CN (1) CN108473518B (ru)
AR (1) AR107472A1 (ru)
AU (1) AU2017211464B9 (ru)
BR (1) BR112018015552A2 (ru)
CA (1) CA3012957A1 (ru)
CO (1) CO2018007788A2 (ru)
HK (1) HK1257616A1 (ru)
MX (1) MX2018009231A (ru)
MY (1) MY195906A (ru)
PH (1) PH12018501586A1 (ru)
RU (1) RU2731615C2 (ru)
SG (1) SG11201806125UA (ru)
TW (1) TWI730039B (ru)
WO (1) WO2017131127A1 (ru)
ZA (1) ZA201804945B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021006004A2 (pt) 2018-10-11 2021-06-29 Sanifit Therapeutics S.A. inositol fosfatos para o tratamento de calcificações ectópicas.
EP4015494A1 (en) 2020-12-15 2022-06-22 Sanifit Therapeutics S.A. Processes for the preparation of soluble salts of inositol phosphates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3540150A1 (de) 1985-11-13 1987-05-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DD298267A5 (de) 1989-01-27 1992-02-13 Zentralinstitut Fuer Molekularbiologie,De Verfahren zur immobilisierung von lipase, beta-galactosidase oder invertase
FI89364C (fi) 1990-12-20 1993-09-27 Leiras Oy Foerfarande foer framstaellning av nya, farmakologiskt anvaendbara metylenbisfosfonsyraderivat
FI89366C (fi) 1990-12-20 1993-09-27 Leiras Oy Foerfarande foer framstaellning av nya farmakologiskt anvaendbara metylenbisfosfonsyraderivat
NZ253524A (en) * 1992-05-29 1997-01-29 Procter & Gamble Pharma Sulphur-containing phosphonate derivatives and medicaments (for treating abnormal calcium and phosphate metabolism)
DE69316013T2 (de) 1992-06-30 1998-07-09 Procter & Gamble Pharma Verwendung von phosphinate zur behandlung der osteoporose
EP1267888A4 (en) 2000-01-04 2005-12-28 Univ California USE OF LOW-DOSEED BISPHOSPHONATES FOR PREVENTING THE CALIBRATION OF HEART AND ARTERIES
AU2003268939A1 (en) 2002-10-15 2004-05-04 Novartis Ag Bisphosphonates for the treatment of antheroscleorosis and devices comprising them
CN1705486A (zh) * 2002-10-15 2005-12-07 诺瓦提斯公司 用于治疗动脉粥样硬化的双膦酸类化合物和包含它们的装置
WO2008128056A1 (en) 2004-10-08 2008-10-23 The Board Of Trustees Of The University Of Illinois Bisphosphonate compounds and methods with enhanced potency for multiple targets including fpps, ggpps, and dpps
JP2009530414A (ja) 2006-03-17 2009-08-27 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ ビスホスホネート化合物及び方法
FR2926080B1 (fr) * 2008-01-03 2010-04-02 Univ Nantes Procede de synthese de derives d'acide hydroxy-bisphosphonique

Also Published As

Publication number Publication date
KR20180111791A (ko) 2018-10-11
RU2731615C2 (ru) 2020-09-07
RU2018130994A (ru) 2020-03-03
BR112018015552A2 (pt) 2018-12-26
ZA201804945B (en) 2019-09-25
US10689408B2 (en) 2020-06-23
CN108473518A (zh) 2018-08-31
AU2017211464B9 (en) 2021-07-22
CO2018007788A2 (es) 2018-08-10
EP3409679A1 (en) 2018-12-05
CA3012957A1 (en) 2017-08-03
EP3409679A4 (en) 2019-11-06
MY195906A (en) 2023-02-27
TW201728332A (zh) 2017-08-16
US20190002482A1 (en) 2019-01-03
CN108473518B (zh) 2021-07-06
AU2017211464B2 (en) 2021-07-01
JP6259957B2 (ja) 2018-01-10
SG11201806125UA (en) 2018-08-30
TWI730039B (zh) 2021-06-11
MX2018009231A (es) 2018-11-09
HK1257616A1 (zh) 2019-10-25
JPWO2017131127A1 (ja) 2018-02-01
PH12018501586A1 (en) 2019-04-08
WO2017131127A1 (ja) 2017-08-03
AR107472A1 (es) 2018-05-02
AU2017211464A1 (en) 2018-08-09

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