RU2018125400A - Method for initiating the death of tumor cells with ascorbic acid and HF and microwave energy of wave radiation - Google Patents

Method for initiating the death of tumor cells with ascorbic acid and HF and microwave energy of wave radiation Download PDF

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RU2018125400A
RU2018125400A RU2018125400A RU2018125400A RU2018125400A RU 2018125400 A RU2018125400 A RU 2018125400A RU 2018125400 A RU2018125400 A RU 2018125400A RU 2018125400 A RU2018125400 A RU 2018125400A RU 2018125400 A RU2018125400 A RU 2018125400A
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mhz
ascorbic acid
tumor
death
microwave energy
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RU2018125400A
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Russian (ru)
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RU2736356C2 (en
RU2018125400A3 (en
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Николай Васильевич Цугленок
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Николай Васильевич Цугленок
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/02—Radiation therapy using microwaves

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Claims (2)

1. Способ инициации гибели опухолевых клеток ВЧ и СВЧ энергией, включающий введение 5-10% раствора аскорбата натрия в вену человеку, или 200-400 мг перорально для максимального избирательного накопления аскорбиновой кислоты в 2-4 раза выше в опухолевых тканях, чем в здоровых, отличающийся тем, что инициация избирательной гибели опухолевых клеток проводиться предварительным переводом человека на безуглеводную диету в течение 3-х дней, для создания глюкозного "голодания" онкоклеток и для многократного увеличения электропроводности и диэлектрических потерь опухолевых тканей в сравнении со здоровыми, производится прием аскорбиновой кислоты человеком в мегадозе 12% раствора аскорбаната натрия, с введением раствора в вену или перорально до 500 мг аскорбиновой кислоты и через 4 часа после приема проводится фотоволновая ВЧ и СВЧ избирательная электромагнитная гипертермия опухолевых тканей, со скоростью нагрева опухолевых тканей 0,017°С/сек, в течение 360 сек до температуры опухолевых тканей 43°С, при нагреве здоровых тканей не выше 40°С.1. A method for initiating the death of tumor cells by HF and microwave energy, comprising administering a 5-10% sodium ascorbate solution to a human vein, or 200-400 mg orally for maximum selective accumulation of ascorbic acid, 2-4 times higher in tumor tissues than in healthy , characterized in that the initiation of selective death of tumor cells is carried out by preliminary transferring a person to a carbohydrate-free diet for 3 days, to create glucose “starvation” of cancer cells and to multiply the electrical conductivity and dielectric In comparison with healthy tissue loss, ascorbic acid is taken by a person in a megadose of a 12% sodium ascorbate solution, injected with a solution into a vein or orally up to 500 mg of ascorbic acid and 4 hours after administration, photo-wave RF and microwave selective electromagnetic hyperthermia of the tumor tissue is performed , with a heating rate of tumor tissue of 0.017 ° C / s, for 360 seconds to a temperature of tumor tissue of 43 ° C, when heating healthy tissue is not higher than 40 ° C. 2. Способ по п. 1, отличающийся тем, что нагрев и гипертермия опухолевых тканей, насыщенных раствором аскорбиновой кислотой, производится ВЧ и СВЧ энергией волнового излучения, в соответствии, с глубиной проникновения электромагнитной волны в биологические ткани и с глубиной расположения опухолевых тканей, на разрешенных частотах: f = 13,56 МГц - 1100 см; f = 27 МГц - 545 см; f = 40,68 МГц - 370 см; f = 433,92 МГц - 34,5 см; f = 915 МГц - 16,5 см и f = 2450 МГц - 6,1 см.2. The method according to p. 1, characterized in that the heating and hyperthermia of tumor tissues saturated with a solution of ascorbic acid is produced by the HF and microwave energy of the wave radiation, in accordance with the depth of penetration of the electromagnetic wave into biological tissues and with the depth of the location of the tumor tissue, allowed frequencies: f = 13.56 MHz - 1100 cm; f = 27 MHz - 545 cm; f = 40.68 MHz - 370 cm; f = 433.92 MHz - 34.5 cm; f = 915 MHz - 16.5 cm and f = 2450 MHz - 6.1 cm.
RU2018125400A 2018-07-10 2018-07-10 Method for initiation of tumor cell death with ascorbic acid and hf and uhf wave radiation energy RU2736356C2 (en)

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RU2006113533A (en) * 2006-04-21 2007-11-20 Валерий Иванович Чиссов (RU) METHOD FOR DESTRUCTION OF BIOTABLES AND DEVICE FOR ITS IMPLEMENTATION
RU2468447C1 (en) * 2011-06-27 2012-11-27 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения и социального развития Российской Федерации (ФГБУ "РНИОИ" Минздравсоцразвития России) Method of inducing cytological action on tumour cells
RU2477641C1 (en) * 2011-09-30 2013-03-20 Учреждение Российской академии медицинских наук Российский онкологический научный центр имени Н.Н. Блохина РАМН Method of treating rectal cancer
WO2016196719A2 (en) * 2015-06-02 2016-12-08 The Secant Group, Llc Hyperthermia targeting compositions, devices, and methods for cancer therapy
WO2016209936A1 (en) * 2015-06-22 2016-12-29 Duke University Synergistic nanotherapy systems and methods of use thereof

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