RU2017121906A3 - - Google Patents
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- RU2017121906A3 RU2017121906A3 RU2017121906A RU2017121906A RU2017121906A3 RU 2017121906 A3 RU2017121906 A3 RU 2017121906A3 RU 2017121906 A RU2017121906 A RU 2017121906A RU 2017121906 A RU2017121906 A RU 2017121906A RU 2017121906 A3 RU2017121906 A3 RU 2017121906A3
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/105—Persulfides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/121—Ketones acyclic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462084754P | 2014-11-26 | 2014-11-26 | |
| US62/084,754 | 2014-11-26 | ||
| PCT/US2015/062620 WO2016086103A1 (en) | 2014-11-26 | 2015-11-25 | Fatty acid cysteamine conjugates and their use as activators of autophagy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2017121906A RU2017121906A (ru) | 2018-12-26 |
| RU2017121906A3 true RU2017121906A3 (ru) | 2019-06-03 |
Family
ID=56075027
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017121906A RU2017121906A (ru) | 2014-11-26 | 2015-11-25 | Конъюгаты цистеамина и жирной кислоты и их применение в качестве активаторов аутофагии |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10251845B2 (ru) |
| EP (1) | EP3223818A4 (ru) |
| JP (1) | JP2017535579A (ru) |
| KR (1) | KR20170087926A (ru) |
| CN (1) | CN107205994A (ru) |
| AU (1) | AU2015353492A1 (ru) |
| BR (1) | BR112017010872A2 (ru) |
| CA (1) | CA2968402A1 (ru) |
| HK (1) | HK1243322A1 (ru) |
| IL (2) | IL252456A0 (ru) |
| MA (1) | MA41031A (ru) |
| MX (1) | MX2017006702A (ru) |
| RU (1) | RU2017121906A (ru) |
| WO (1) | WO2016086103A1 (ru) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| ME02970B (me) | 2004-06-24 | 2018-07-20 | Vertex Pharma | Modulatori atp-vezujućih kasetnih transportera |
| HUE032640T2 (en) | 2005-11-08 | 2017-10-30 | Vertex Pharma | Heterocyclic modulator of ATP-binding cassette transcripts |
| LT1993360T (lt) | 2005-12-28 | 2017-06-12 | Vertex Pharmaceuticals Incorporated | N-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksochinolin-3-karboksamido kieta forma |
| US10022352B2 (en) | 2006-04-07 | 2018-07-17 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| US7645789B2 (en) | 2006-04-07 | 2010-01-12 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
| DK3091011T3 (en) | 2006-04-07 | 2018-02-26 | Vertex Pharma | MODULATORS OF ATP BINDING CASSETTE TRANSPORT |
| US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
| US8969386B2 (en) | 2007-05-09 | 2015-03-03 | Vertex Pharmaceuticals Incorporated | Modulators of CFTR |
| KR20100101130A (ko) | 2007-12-07 | 2010-09-16 | 버텍스 파마슈티칼스 인코포레이티드 | 3-(6-(1-(2,2-디플루오로벤조[ｄ][1,3]디옥솔-5-일)사이클로프로판카복스아미도)-3-메틸피리딘-2-일)벤조산의 고체 형태 |
| CA2707494C (en) | 2007-12-07 | 2018-04-24 | Vertex Pharmaceuticals Incorporated | Processes for producing cycloalkylcarboxamido-pyridine benzoic acids |
| NZ602030A (en) | 2008-02-28 | 2014-02-28 | Vertex Pharma | Heteroaryl derivatives as cftr modulators |
| EP2821400B1 (en) | 2009-03-20 | 2017-09-27 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US8802868B2 (en) | 2010-03-25 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide |
| LT3150198T (lt) | 2010-04-07 | 2021-12-10 | Vertex Pharmaceuticals Incorporated | 3-(6-(1-(2,2-difluorbenzo[d][1,3]dioksol-5-il) ciklopropankarboksamido)-3-metilpiridin-2-il)benzoinės rūgšties farmacinė kompozicija ir jos įvedimas |
| SG184987A1 (en) | 2010-04-22 | 2012-11-29 | Vertex Pharma | Process of producing cycloalkylcarboxamido-indole compounds |
| WO2013130669A1 (en) | 2012-02-27 | 2013-09-06 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administration thereof |
| AU2013290444B2 (en) | 2012-07-16 | 2018-04-26 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of (R)-1-(2,2-diflurorbenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl) cyclopropanecarboxamide and administration thereof |
| PT3068392T (pt) | 2013-11-12 | 2021-05-14 | Vertex Pharma | Processo de preparação de composições farmacêuticas para o tratamento de doenças mediadas por condutância transmembrana da fibrose quística (cftr) |
| PL3925607T3 (pl) | 2014-04-15 | 2023-10-30 | Vertex Pharmaceuticals Incorporated | Kompozycje farmaceutyczne do leczenia chorób, w których pośredniczy mukowiscydozowy przezbłonowy regulator przewodnictwa |
| HUE055423T2 (hu) | 2014-11-18 | 2021-11-29 | Vertex Pharma | Eljárás nagy áteresztõképességû tesztelõ nagy teljesítményû folyadék-kromatográfia elvégzésére |
| MA41031A (fr) * | 2014-11-26 | 2017-10-03 | Catabasis Pharmaceuticals Inc | Conjugués cystéamine-acide gras et leur utilisation comme activateurs de l'autophagie |
| WO2018144981A1 (en) * | 2017-02-06 | 2018-08-09 | StemBios Technologies, Inc. | Use of somatic stem cells for increasing autophagy |
| AU2018305726B2 (en) | 2017-07-26 | 2022-09-15 | The University Of Queensland | Disulfide bond containing compounds and uses thereof |
| WO2021061858A1 (en) * | 2019-09-25 | 2021-04-01 | Frontier Medicines Corporation | Targeted autophagy conjugates and methods |
| US20230099696A1 (en) * | 2020-03-11 | 2023-03-30 | Purdue Research Foundation | Nano-composite microparticles of polymyxin |
| US20240009148A1 (en) * | 2020-11-19 | 2024-01-11 | Birch Therapeutics, Inc. | Cystamine Formulations and Uses Thereof |
| CN115724786B (zh) * | 2021-09-01 | 2024-01-30 | 四川大学 | 酰胺烷二硫邻苯二甲酰亚胺类化合物、其制备方法和用途 |
| CN115806514A (zh) * | 2022-12-06 | 2023-03-17 | 航天材料及工艺研究所 | 一种基于动态二硫键的无溶剂型自修复聚氨酯及其制备方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
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| ES2656793T3 (es) | 2008-07-08 | 2018-02-28 | Catabasis Pharmaceuticals, Inc. | Salicilatos acetilados de ácidos grasos y sus usos |
| US9085527B2 (en) | 2008-07-08 | 2015-07-21 | Catabasis Pharmaceuticals, Inc. | Fatty acid acylated salicylates and their uses |
| BR112012004677A2 (pt) | 2009-09-01 | 2020-11-03 | Catabasis Pharmaceuticals, Inc. | conjugados de ácido graxo niacina e seus usos |
| USRE46608E1 (en) | 2009-09-01 | 2017-11-14 | Catabasis Pharmaceuticals, Inc. | Fatty acid niacin conjugates and their uses |
| US20110082202A1 (en) | 2009-10-05 | 2011-04-07 | Milne Jill C | Fatty acid acifran derivatives and their uses |
| WO2011044141A1 (en) | 2009-10-05 | 2011-04-14 | Catabasis Pharmaceuticals, Inc. | Fatty acid fibrate derivatives and their uses |
| US20110082120A1 (en) | 2009-10-05 | 2011-04-07 | Milne Jill C | Substituted thioacetic acid salicylate derivatives and their uses |
| US20110082156A1 (en) | 2009-10-05 | 2011-04-07 | Milne Jill C | Fatty acid acipimox derivatives and their uses |
| US8946451B2 (en) | 2009-10-05 | 2015-02-03 | Catabasis Pharmaceuticals, Inc. | Lipoic acid acylated salicylate derivatives and their uses |
| WO2011085211A1 (en) | 2010-01-08 | 2011-07-14 | Catabasis Pharmaceuticals, Inc. | Fatty acid fumarate derivatives and their uses |
| US20130190327A1 (en) | 2010-02-26 | 2013-07-25 | Catabasis Pharmaceuticals Inc | Bis-fatty acid conjugates and their uses |
| US20110213028A1 (en) | 2010-02-26 | 2011-09-01 | Catabasis Pharmaceuticals, Inc. | Fatty acid mycophenolate derivatives and their uses |
| US20110212958A1 (en) | 2010-02-26 | 2011-09-01 | Catabasis Pharmaceuticals, Inc. | Fatty acid raloxifene derivatives and their uses |
| WO2011109681A1 (en) | 2010-03-05 | 2011-09-09 | Catabasis Pharmaceuticals, Inc. | Fatty acid cox inhibitor derivatives and their uses |
| US20130045939A1 (en) | 2010-03-19 | 2013-02-21 | Catabasis Pharmaceuticals, Inc. | Fatty acid macrolide derivatives and their uses |
| WO2012115695A1 (en) | 2011-02-25 | 2012-08-30 | Catabasis Pharmaceuticals, Inc. | Bis-fatty acid conjugates and their uses |
| WO2012161798A1 (en) | 2011-02-25 | 2012-11-29 | Catabasis Pharmaceuticals, Inc. | Fatty acid gamma aminobutyric acid (gaba) conjugates and their uses |
| EP2685969A4 (en) | 2011-03-18 | 2014-08-06 | Catabasis Pharmaceuticals Inc | USE OF INTRACELLULAR ENZYMES TO RELEASE BIOACTIVE PRODUCTS RELATED TO COVALENCE |
| US20120252810A1 (en) | 2011-04-04 | 2012-10-04 | Catabasis Pharmaceuticals, Inc. | Fatty acid non-flushing niacin derivatives and their uses |
| WO2012149352A1 (en) | 2011-04-29 | 2012-11-01 | Catabasis Pharmaceuticals, Inc. | Fatty acid guanidine and salicylate guanidine derivatives and their uses |
| WO2012154554A1 (en) | 2011-05-06 | 2012-11-15 | Catabasis Pharmaceuticals, Inc. | Fatty acid triterpene derivatives and their uses |
| US9029548B2 (en) | 2011-05-06 | 2015-05-12 | Catabasis Pharmaceuticals, Inc. | Fatty acid lenalidomide derivatives and their uses |
| WO2012154564A1 (en) | 2011-05-06 | 2012-11-15 | Catabasis Pharmaceuticals, Inc. | Fatty acid phenolic derivatives and their uses |
| WO2014045293A1 (en) | 2012-09-24 | 2014-03-27 | Krisani Bioscience (P) Ltd. | Fatty acid amides with a cysteamine or an acetylated cysteamine group and uses thereof |
| US20130059801A1 (en) * | 2011-08-31 | 2013-03-07 | Catabasis Pharmaceuticals, Inc. | Fatty acid amides, compositions and methods of use |
| ES2773376T3 (es) | 2011-08-31 | 2020-07-10 | Catabasis Pharmaceuticals Inc | Amidas de ácidos grasos, composiciones y procedimientos de uso |
| US20130244966A1 (en) | 2011-12-12 | 2013-09-19 | Catabasis Pharmaceuticals, Inc. | Fatty acid antiviral conjugates and their uses |
| MX2014013150A (es) | 2012-05-01 | 2015-05-11 | Catabasis Pharmaceuticals Inc | Conjugados de acidos grasos de estatina y agonistas fxr, composiciones y metodos de uso. |
| CN104487060A (zh) | 2012-05-25 | 2015-04-01 | 克塔巴西斯制药有限公司 | 使前蛋白转化酶枯草溶菌素/kexin 9型(pcsk9)减少的方法 |
| US20150352094A1 (en) | 2013-01-07 | 2015-12-10 | Catabasis Pharmaceuticals, Inc. | Use of fatty acid niacin conjugates for treating diseases |
| US20140288025A1 (en) | 2013-03-13 | 2014-09-25 | Catabasis Pharmaceuticals, Inc. | Fatty acid antiviral conjugates and their uses |
| WO2014204856A1 (en) | 2013-06-17 | 2014-12-24 | Catabasis Pharmaceuticals, Inc. | Fatty acid anticancer derivatives and their uses |
| US20160287712A1 (en) | 2013-11-15 | 2016-10-06 | Catabasis Pharmaceuticals, Inc. | Fatty acid niacin conjugates |
| MA41031A (fr) * | 2014-11-26 | 2017-10-03 | Catabasis Pharmaceuticals Inc | Conjugués cystéamine-acide gras et leur utilisation comme activateurs de l'autophagie |
| WO2016086136A1 (en) | 2014-11-26 | 2016-06-02 | Catabasis Pharmaceuticals, Inc. | Fatty acid cysteamine conjugates of cftr modulators and their use in treating medical disorders |
| US20170342046A1 (en) | 2016-05-24 | 2017-11-30 | Catabasis Pharmaceuticals, Inc. | Fatty Acid Cysteine-Based Conjugates and Their Use in Treating Medical Disorders |
-
2015
- 2015-11-24 MA MA041031A patent/MA41031A/fr unknown
- 2015-11-25 CA CA2968402A patent/CA2968402A1/en not_active Abandoned
- 2015-11-25 US US15/529,316 patent/US10251845B2/en not_active Expired - Fee Related
- 2015-11-25 CN CN201580074492.1A patent/CN107205994A/zh active Pending
- 2015-11-25 AU AU2015353492A patent/AU2015353492A1/en not_active Abandoned
- 2015-11-25 WO PCT/US2015/062620 patent/WO2016086103A1/en active Application Filing
- 2015-11-25 JP JP2017527914A patent/JP2017535579A/ja active Pending
- 2015-11-25 KR KR1020177017015A patent/KR20170087926A/ko unknown
- 2015-11-25 MX MX2017006702A patent/MX2017006702A/es active IP Right Grant
- 2015-11-25 BR BR112017010872-0A patent/BR112017010872A2/pt not_active Application Discontinuation
- 2015-11-25 RU RU2017121906A patent/RU2017121906A/ru unknown
- 2015-11-25 EP EP15862737.2A patent/EP3223818A4/en not_active Withdrawn
-
2017
- 2017-05-23 IL IL252456A patent/IL252456A0/en unknown
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2018
- 2018-02-26 HK HK18102742.7A patent/HK1243322A1/zh unknown
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2019
- 2019-04-08 US US16/377,723 patent/US20200038342A1/en not_active Abandoned
-
2020
- 2020-06-22 IL IL275578A patent/IL275578A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US10251845B2 (en) | 2019-04-09 |
| JP2017535579A (ja) | 2017-11-30 |
| CA2968402A1 (en) | 2016-06-02 |
| US20200038342A1 (en) | 2020-02-06 |
| EP3223818A4 (en) | 2018-04-25 |
| MX2017006702A (es) | 2018-01-11 |
| KR20170087926A (ko) | 2017-07-31 |
| WO2016086103A1 (en) | 2016-06-02 |
| US20170258741A1 (en) | 2017-09-14 |
| CN107205994A (zh) | 2017-09-26 |
| IL252456A0 (en) | 2017-07-31 |
| MA41031A (fr) | 2017-10-03 |
| HK1243322A1 (zh) | 2018-07-13 |
| IL275578A (en) | 2020-08-31 |
| BR112017010872A2 (pt) | 2018-01-09 |
| RU2017121906A (ru) | 2018-12-26 |
| AU2015353492A1 (en) | 2017-06-08 |
| EP3223818A1 (en) | 2017-10-04 |