RU2016144355A - Бициклические производные и фармацевтическая композиция, содержащая их - Google Patents
Бициклические производные и фармацевтическая композиция, содержащая их Download PDFInfo
- Publication number
- RU2016144355A RU2016144355A RU2016144355A RU2016144355A RU2016144355A RU 2016144355 A RU2016144355 A RU 2016144355A RU 2016144355 A RU2016144355 A RU 2016144355A RU 2016144355 A RU2016144355 A RU 2016144355A RU 2016144355 A RU2016144355 A RU 2016144355A
- Authority
- RU
- Russia
- Prior art keywords
- triol
- pyran
- tetrahydro
- hydroxymethyl
- dihydro
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/04—Carbocyclic radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2014-0057428 | 2014-05-13 | ||
| KR1020140057428A KR20150130177A (ko) | 2014-05-13 | 2014-05-13 | Sglt 저해제로서 2,3-다이하이드로벤조퓨란 유도체 및 이를 포함하는 약학적 조성물 |
| KR1020140081343A KR20160002257A (ko) | 2014-06-30 | 2014-06-30 | Sglt 저해제로서 인단 유도체 및 이를 포함하는 약학적 조성물 |
| KR10-2014-0081343 | 2014-06-30 | ||
| PCT/KR2015/004643 WO2015174695A1 (fr) | 2014-05-13 | 2015-05-08 | Dérivés bicycliques et composition pharmaceutique les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2016144355A true RU2016144355A (ru) | 2018-06-19 |
Family
ID=54480186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016144355A RU2016144355A (ru) | 2014-05-13 | 2015-05-08 | Бициклические производные и фармацевтическая композиция, содержащая их |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9828366B2 (fr) |
| EP (1) | EP3143017A4 (fr) |
| JP (1) | JP2017515846A (fr) |
| CN (1) | CN105085454A (fr) |
| AU (1) | AU2015260082A1 (fr) |
| CA (1) | CA2948130A1 (fr) |
| CL (1) | CL2016002870A1 (fr) |
| IL (1) | IL248490A0 (fr) |
| MX (1) | MX2016013760A (fr) |
| PH (1) | PH12016502226A1 (fr) |
| RU (1) | RU2016144355A (fr) |
| SG (1) | SG11201608660TA (fr) |
| TW (1) | TW201623321A (fr) |
| WO (1) | WO2015174695A1 (fr) |
| ZA (1) | ZA201607353B (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2802443C1 (ru) * | 2020-02-27 | 2023-08-29 | Тэвун Фармасьютикал Ко., Лтд. | Промежуточное соединение, применяемое для синтеза ингибитора sglt, и способ получения ингибитора sglt с применением указанного промежуточного соединения |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE051212T2 (hu) * | 2016-01-04 | 2021-03-01 | Jeil Pharmaceutical Co Ltd | Kondenzált fenilgyûrût tartalmazó C-glükozid származék vagy annak gyógyászatilag elfogadható sója, eljárás annak elõállítására és azt tartalmazó gyógyászati kompozíció |
| CN114539231B (zh) * | 2020-11-19 | 2023-11-21 | 北京盈科瑞创新药物研究有限公司 | 一种糖苷类衍生物及其制备方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5470845A (en) | 1992-10-28 | 1995-11-28 | Bristol-Myers Squibb Company | Methods of using α-phosphonosulfonate squalene synthetase inhibitors including the treatment of atherosclerosis and hypercholesterolemia |
| US5739135A (en) | 1993-09-03 | 1998-04-14 | Bristol-Myers Squibb Company | Inhibitors of microsomal triglyceride transfer protein and method |
| US5760246A (en) | 1996-12-17 | 1998-06-02 | Biller; Scott A. | Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method |
| PH12000002657B1 (en) * | 1999-10-12 | 2006-02-21 | Bristol Myers Squibb Co | C-aryl glucoside SGLT2 inhibitors |
| US6627611B2 (en) * | 2000-02-02 | 2003-09-30 | Kotobuki Pharmaceutical Co Ltd | C-glycosides and preparation of thereof as antidiabetic agents |
| AU2002212109A1 (en) * | 2000-11-10 | 2002-05-21 | Novo-Nordisk A/S | 1,3-diazaheterocyclic compounds and their use as oral hypoglycaemic agents |
| EP1495019B1 (fr) | 2002-04-08 | 2008-07-02 | Council of Scientific and Industrial Research | Glucopyranoside, son procede d'isolation, composition pharmaceutique contenant ledit glucopyranoside |
| PL1980560T3 (pl) * | 2003-03-14 | 2011-11-30 | Astellas Pharma Inc | Pochodne C-glikozydowe do leczenia cukrzycy |
| AR045173A1 (es) * | 2003-08-01 | 2005-10-19 | Tanabe Seiyaku Co | Compuestos que poseen actividad inhibitoria contra transportador de glucosa dependiente de sodio |
| WO2006082245A1 (fr) | 2005-02-07 | 2006-08-10 | Novo Nordisk A/S | Reparations pharmaceutiques comprenant de l'insuline, des ions de zinc et un ligand de liaison au zinc |
| WO2010074219A1 (fr) * | 2008-12-26 | 2010-07-01 | アステラス製薬株式会社 | Composé de benzothiophène |
-
2015
- 2015-05-06 TW TW104114467A patent/TW201623321A/zh unknown
- 2015-05-08 CA CA2948130A patent/CA2948130A1/fr not_active Abandoned
- 2015-05-08 RU RU2016144355A patent/RU2016144355A/ru unknown
- 2015-05-08 US US15/308,435 patent/US9828366B2/en active Active
- 2015-05-08 AU AU2015260082A patent/AU2015260082A1/en not_active Abandoned
- 2015-05-08 MX MX2016013760A patent/MX2016013760A/es unknown
- 2015-05-08 JP JP2016567513A patent/JP2017515846A/ja active Pending
- 2015-05-08 WO PCT/KR2015/004643 patent/WO2015174695A1/fr active Application Filing
- 2015-05-08 EP EP15792426.7A patent/EP3143017A4/fr not_active Withdrawn
- 2015-05-08 SG SG11201608660TA patent/SG11201608660TA/en unknown
- 2015-05-12 CN CN201510239295.2A patent/CN105085454A/zh active Pending
-
2016
- 2016-10-25 IL IL248490A patent/IL248490A0/en unknown
- 2016-10-25 ZA ZA2016/07353A patent/ZA201607353B/en unknown
- 2016-11-09 PH PH12016502226A patent/PH12016502226A1/en unknown
- 2016-11-10 CL CL2016002870A patent/CL2016002870A1/es unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2802443C1 (ru) * | 2020-02-27 | 2023-08-29 | Тэвун Фармасьютикал Ко., Лтд. | Промежуточное соединение, применяемое для синтеза ингибитора sglt, и способ получения ингибитора sglt с применением указанного промежуточного соединения |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2948130A1 (fr) | 2015-11-19 |
| CN105085454A (zh) | 2015-11-25 |
| PH12016502226A1 (en) | 2017-01-09 |
| SG11201608660TA (en) | 2016-11-29 |
| EP3143017A1 (fr) | 2017-03-22 |
| AU2015260082A1 (en) | 2016-11-03 |
| US20170066750A1 (en) | 2017-03-09 |
| IL248490A0 (en) | 2016-12-29 |
| WO2015174695A1 (fr) | 2015-11-19 |
| US9828366B2 (en) | 2017-11-28 |
| ZA201607353B (en) | 2018-05-30 |
| CL2016002870A1 (es) | 2017-08-18 |
| EP3143017A4 (fr) | 2017-12-13 |
| JP2017515846A (ja) | 2017-06-15 |
| MX2016013760A (es) | 2017-03-09 |
| TW201623321A (zh) | 2016-07-01 |
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