RU2016138574A - Способ лечения депрессии и депрессивного эпизода тяжелой степени - Google Patents
Способ лечения депрессии и депрессивного эпизода тяжелой степени Download PDFInfo
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- RU2016138574A RU2016138574A RU2016138574A RU2016138574A RU2016138574A RU 2016138574 A RU2016138574 A RU 2016138574A RU 2016138574 A RU2016138574 A RU 2016138574A RU 2016138574 A RU2016138574 A RU 2016138574A RU 2016138574 A RU2016138574 A RU 2016138574A
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- 238000000034 method Methods 0.000 title claims 81
- 208000020401 Depressive disease Diseases 0.000 title claims 7
- 102000014814 CACNA1C Human genes 0.000 claims 54
- 101000867811 Homo sapiens Voltage-dependent L-type calcium channel subunit alpha-1C Proteins 0.000 claims 54
- 101000785573 Homo sapiens Zinc finger and SCAN domain-containing protein 4 Proteins 0.000 claims 50
- 102100026569 Zinc finger and SCAN domain-containing protein 4 Human genes 0.000 claims 50
- 102100040750 CUB and sushi domain-containing protein 1 Human genes 0.000 claims 48
- 101000892017 Homo sapiens CUB and sushi domain-containing protein 1 Proteins 0.000 claims 48
- 102100028284 Collagen alpha-1(XXVI) chain Human genes 0.000 claims 38
- 101000860862 Homo sapiens Collagen alpha-1(XXVI) chain Proteins 0.000 claims 38
- 101000802315 Homo sapiens Zinc finger protein 551 Proteins 0.000 claims 31
- 102100034649 Zinc finger protein 551 Human genes 0.000 claims 31
- 101000817629 Homo sapiens Dymeclin Proteins 0.000 claims 26
- 102100035433 FOXL2 neighbor protein Human genes 0.000 claims 22
- 101000877721 Homo sapiens FOXL2 neighbor protein Proteins 0.000 claims 22
- 108091029795 Intergenic region Proteins 0.000 claims 15
- 108020004707 nucleic acids Proteins 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 12
- 102000039446 nucleic acids Human genes 0.000 claims 12
- YQNWZWMKLDQSAC-UHFFFAOYSA-N vortioxetine Chemical compound CC1=CC(C)=CC=C1SC1=CC=CC=C1N1CCNCC1 YQNWZWMKLDQSAC-UHFFFAOYSA-N 0.000 claims 9
- 229960002263 vortioxetine Drugs 0.000 claims 9
- 239000000523 sample Substances 0.000 claims 8
- 102100021242 Dymeclin Human genes 0.000 claims 7
- 239000012472 biological sample Substances 0.000 claims 5
- 230000002068 genetic effect Effects 0.000 claims 5
- -1 LINC00348 Proteins 0.000 claims 4
- 238000003759 clinical diagnosis Methods 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 4
- 208000028698 Cognitive impairment Diseases 0.000 claims 3
- 238000004458 analytical method Methods 0.000 claims 3
- 208000010877 cognitive disease Diseases 0.000 claims 3
- 108020004414 DNA Proteins 0.000 claims 2
- 239000013060 biological fluid Substances 0.000 claims 2
- 239000002299 complementary DNA Substances 0.000 claims 2
- 238000010839 reverse transcription Methods 0.000 claims 2
- 238000012163 sequencing technique Methods 0.000 claims 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461948529P | 2014-03-05 | 2014-03-05 | |
| US61/948,529 | 2014-03-05 | ||
| US201462061417P | 2014-10-08 | 2014-10-08 | |
| US62/061,417 | 2014-10-08 | ||
| PCT/US2015/018701 WO2015134585A1 (en) | 2014-03-05 | 2015-03-04 | Method for treating depression and major depressive disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2016138574A true RU2016138574A (ru) | 2018-04-06 |
| RU2016138574A3 RU2016138574A3 (https=) | 2018-10-12 |
Family
ID=54055831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016138574A RU2016138574A (ru) | 2014-03-05 | 2015-03-04 | Способ лечения депрессии и депрессивного эпизода тяжелой степени |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20170137880A1 (https=) |
| EP (1) | EP3114239A4 (https=) |
| JP (1) | JP2017512204A (https=) |
| KR (1) | KR20160127126A (https=) |
| CN (1) | CN106536751A (https=) |
| AU (1) | AU2015227296A1 (https=) |
| CA (1) | CA2940683A1 (https=) |
| IL (1) | IL247379A0 (https=) |
| MA (1) | MA39485A (https=) |
| MX (1) | MX2016011384A (https=) |
| RU (1) | RU2016138574A (https=) |
| WO (1) | WO2015134585A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017087735A1 (en) * | 2015-11-18 | 2017-05-26 | Millennium Pharmaceuticals, Inc. | Method for treating crohn's disease |
| US20190216803A1 (en) | 2017-03-30 | 2019-07-18 | Rundle Research, LLC | Methods of treating depression with vortioxetine |
| DK3528811T3 (da) * | 2017-03-30 | 2021-09-27 | Rundle Res Llc | Vortioxetin og mao-inhibitorer til behandling af depression |
| EP3909600A1 (en) * | 2020-05-12 | 2021-11-17 | International Centre For Genetic Engineering And Biotechnology - ICGEB | Emid2 protein as anti-cancer treatment |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2044043B2 (en) * | 2006-06-16 | 2021-03-03 | H. Lundbeck A/S | 1- ý[- (2, 4-dimethylphenylsulfanyl) -phenyl]piperazine hydrobromide as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment |
| EP2581453A3 (en) * | 2008-01-17 | 2013-07-10 | Suregene Llc | Genetic Markers of Mental Illness |
| US20140045915A1 (en) * | 2010-08-31 | 2014-02-13 | The General Hospital Corporation | Cancer-related biological materials in microvesicles |
| US20130274133A1 (en) * | 2010-10-01 | 2013-10-17 | Rigshospitalet | Genetic variations in the interleukin-6 receptor gene as predictors of the response of patients to treatment with interleukin-6 receptor inhibitors |
| WO2012109565A1 (en) * | 2011-02-10 | 2012-08-16 | Neurotherics, Llc | Genetic identification of response to antidepressant medications |
| US9243464B2 (en) * | 2011-02-10 | 2016-01-26 | Baker Hughes Incorporated | Flow control device and methods for using same |
| KR102035877B1 (ko) * | 2011-11-14 | 2019-10-23 | 알파시그마 에스.피.에이. | 우울증이 있는 대상체를 위한 치료 양생법 선택을 위한 검정법 및 치료 방법 |
-
2015
- 2015-03-04 JP JP2016554883A patent/JP2017512204A/ja active Pending
- 2015-03-04 EP EP15758563.9A patent/EP3114239A4/en not_active Withdrawn
- 2015-03-04 RU RU2016138574A patent/RU2016138574A/ru not_active Application Discontinuation
- 2015-03-04 WO PCT/US2015/018701 patent/WO2015134585A1/en not_active Ceased
- 2015-03-04 KR KR1020167027125A patent/KR20160127126A/ko not_active Withdrawn
- 2015-03-04 CN CN201580023401.1A patent/CN106536751A/zh active Pending
- 2015-03-04 AU AU2015227296A patent/AU2015227296A1/en not_active Abandoned
- 2015-03-04 CA CA2940683A patent/CA2940683A1/en not_active Abandoned
- 2015-03-04 MX MX2016011384A patent/MX2016011384A/es unknown
- 2015-03-04 US US15/123,072 patent/US20170137880A1/en not_active Abandoned
- 2015-03-04 MA MA039485A patent/MA39485A/fr unknown
-
2016
- 2016-08-21 IL IL247379A patent/IL247379A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20160127126A (ko) | 2016-11-02 |
| EP3114239A1 (en) | 2017-01-11 |
| MA39485A (fr) | 2015-09-11 |
| EP3114239A4 (en) | 2017-10-11 |
| WO2015134585A1 (en) | 2015-09-11 |
| US20170137880A1 (en) | 2017-05-18 |
| CA2940683A1 (en) | 2015-09-11 |
| IL247379A0 (en) | 2016-11-30 |
| JP2017512204A (ja) | 2017-05-18 |
| AU2015227296A1 (en) | 2016-09-08 |
| MX2016011384A (es) | 2017-05-01 |
| RU2016138574A3 (https=) | 2018-10-12 |
| CN106536751A (zh) | 2017-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20190129 |