RU2016122038A3 - - Google Patents
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- RU2016122038A3 RU2016122038A3 RU2016122038A RU2016122038A RU2016122038A3 RU 2016122038 A3 RU2016122038 A3 RU 2016122038A3 RU 2016122038 A RU2016122038 A RU 2016122038A RU 2016122038 A RU2016122038 A RU 2016122038A RU 2016122038 A3 RU2016122038 A3 RU 2016122038A3
- Authority
- RU
- Russia
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8209—Selection, visualisation of transformants, reporter constructs, e.g. antibiotic resistance markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8209—Selection, visualisation of transformants, reporter constructs, e.g. antibiotic resistance markers
- C12N15/821—Non-antibiotic resistance markers, e.g. morphogenetic, metabolic markers
- C12N15/8212—Colour markers, e.g. beta-glucoronidase [GUS], green fluorescent protein [GFP], carotenoid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
- C12N15/8275—Glyphosate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361899543P | 2013-11-04 | 2013-11-04 | |
| US61/899,543 | 2013-11-04 | ||
| PCT/US2014/063732 WO2015066637A1 (en) | 2013-11-04 | 2014-11-03 | A universal donor system for gene targeting |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2016122038A RU2016122038A (ru) | 2017-12-11 |
| RU2016122038A3 true RU2016122038A3 (enExample) | 2018-06-21 |
| RU2687369C2 RU2687369C2 (ru) | 2019-05-13 |
Family
ID=53005271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016122038A RU2687369C2 (ru) | 2013-11-04 | 2014-11-03 | Универсальная донорная система для направленного воздействия на гены |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10077449B2 (enExample) |
| EP (1) | EP3066192B1 (enExample) |
| JP (1) | JP6560203B2 (enExample) |
| KR (1) | KR102248730B1 (enExample) |
| CN (1) | CN105683357B (enExample) |
| AR (1) | AR098283A1 (enExample) |
| AU (1) | AU2014341928B2 (enExample) |
| BR (1) | BR102014027448A8 (enExample) |
| CA (1) | CA2926534A1 (enExample) |
| IL (1) | IL245313B (enExample) |
| RU (1) | RU2687369C2 (enExample) |
| TW (1) | TWI669395B (enExample) |
| WO (1) | WO2015066637A1 (enExample) |
| ZA (1) | ZA201601929B (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013024337A2 (pt) | 2011-03-23 | 2017-09-26 | Du Pont | locus de traço transgênico complexo em uma planta, planta ou semente, método para produzir em uma planta um locus de traço transgênico complexo e construto de expressão |
| WO2013066438A2 (en) | 2011-07-22 | 2013-05-10 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9737604B2 (en) | 2013-09-06 | 2017-08-22 | President And Fellows Of Harvard College | Use of cationic lipids to deliver CAS9 |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| KR20230054509A (ko) | 2013-11-07 | 2023-04-24 | 에디타스 메디신, 인코포레이티드 | 지배적인 gRNA를 이용하는 CRISPR-관련 방법 및 조성물 |
| US11053481B2 (en) | 2013-12-12 | 2021-07-06 | President And Fellows Of Harvard College | Fusions of Cas9 domains and nucleic acid-editing domains |
| AU2015298571B2 (en) | 2014-07-30 | 2020-09-03 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| WO2016040030A1 (en) | 2014-09-12 | 2016-03-17 | E. I. Du Pont De Nemours And Company | Generation of site-specific-integration sites for complex trait loci in corn and soybean, and methods of use |
| CN107250148B (zh) | 2014-12-03 | 2021-04-16 | 安捷伦科技有限公司 | 具有化学修饰的指导rna |
| KR102046450B1 (ko) | 2015-01-27 | 2019-11-19 | 인스티튜트 오브 제네틱스 앤드 디벨롭멘털 바이오롤지, 차이니즈 아카데미 오브 사이언시스 | 일시적인 유전자 발현을 통해 완전한 식물에서 부위-특이적인 변형을 수행하는 방법 |
| ES2884838T3 (es) | 2015-04-06 | 2021-12-13 | Univ Leland Stanford Junior | ARN guía químicamente modificados para la regulación génica mediada por CRISPR/CAS |
| EP3095870A1 (en) | 2015-05-19 | 2016-11-23 | Kws Saat Se | Methods for the in planta transformation of plants and manufacturing processes and products based and obtainable therefrom |
| CA2994883A1 (en) * | 2015-08-14 | 2017-02-23 | Institute Of Genetics And Developmental Biology, Chinese Academy Of Scnces | Method for obtaining glyphosate-resistant rice by site-directed nucleotide substitution |
| WO2017040967A1 (en) * | 2015-09-04 | 2017-03-09 | Octavo Systems Llc | Improved system using system in package components |
| US12043852B2 (en) | 2015-10-23 | 2024-07-23 | President And Fellows Of Harvard College | Evolved Cas9 proteins for gene editing |
| US11306308B2 (en) | 2015-11-13 | 2022-04-19 | Massachusetts Institute Of Technology | High-throughput CRISPR-based library screening |
| US10767175B2 (en) | 2016-06-08 | 2020-09-08 | Agilent Technologies, Inc. | High specificity genome editing using chemically modified guide RNAs |
| KR20250103795A (ko) | 2016-08-03 | 2025-07-07 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 아데노신 핵염기 편집제 및 그의 용도 |
| CN109804066A (zh) | 2016-08-09 | 2019-05-24 | 哈佛大学的校长及成员们 | 可编程cas9-重组酶融合蛋白及其用途 |
| US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| AU2017342543B2 (en) | 2016-10-14 | 2024-06-27 | President And Fellows Of Harvard College | AAV delivery of nucleobase editors |
| WO2018119359A1 (en) | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
| CN106591293A (zh) * | 2016-12-28 | 2017-04-26 | 贵州省草业研究所 | 基于酶切连接从未知基因组中分离已知序列侧翼序列的方法 |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| EP3592381A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Cancer vaccine |
| KR20190127797A (ko) | 2017-03-10 | 2019-11-13 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 시토신에서 구아닌으로의 염기 편집제 |
| CA3057192A1 (en) | 2017-03-23 | 2018-09-27 | President And Fellows Of Harvard College | Nucleobase editors comprising nucleic acid programmable dna binding proteins |
| WO2018209320A1 (en) | 2017-05-12 | 2018-11-15 | President And Fellows Of Harvard College | Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation |
| CN111801345A (zh) | 2017-07-28 | 2020-10-20 | 哈佛大学的校长及成员们 | 使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物 |
| WO2019139645A2 (en) | 2017-08-30 | 2019-07-18 | President And Fellows Of Harvard College | High efficiency base editors comprising gam |
| CA3082251A1 (en) | 2017-10-16 | 2019-04-25 | The Broad Institute, Inc. | Uses of adenosine base editors |
| CN107545153B (zh) * | 2017-10-25 | 2021-06-11 | 桂林电子科技大学 | 一种基于卷积神经网络的核小体分类预测方法 |
| EP3724214A4 (en) | 2017-12-15 | 2021-09-01 | The Broad Institute Inc. | SYSTEMS AND METHODS FOR PREDICTING REPAIR RESULTS IN GENETIC ENGINEERING |
| WO2019226953A1 (en) | 2018-05-23 | 2019-11-28 | The Broad Institute, Inc. | Base editors and uses thereof |
| GB2611929B (en) | 2018-10-16 | 2023-11-22 | Blueallele Corp | Methods for targeted insertion of DNA in genes |
| US12281338B2 (en) | 2018-10-29 | 2025-04-22 | The Broad Institute, Inc. | Nucleobase editors comprising GeoCas9 and uses thereof |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| DE112020001306T5 (de) | 2019-03-19 | 2022-01-27 | Massachusetts Institute Of Technology | Verfahren und zusammensetzungen zur editierung von nukleotidsequenzen |
| US12473543B2 (en) | 2019-04-17 | 2025-11-18 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| US12435330B2 (en) | 2019-10-10 | 2025-10-07 | The Broad Institute, Inc. | Methods and compositions for prime editing RNA |
| JP2023525304A (ja) | 2020-05-08 | 2023-06-15 | ザ ブロード インスティテュート，インコーポレーテッド | 標的二本鎖ヌクレオチド配列の両鎖同時編集のための方法および組成物 |
| CN114317588B (zh) * | 2020-09-29 | 2023-06-27 | 中国农业科学院生物技术研究所 | 一种作物高温响应型基因组精准甲基化调控回路 |
| US11884915B2 (en) | 2021-09-10 | 2024-01-30 | Agilent Technologies, Inc. | Guide RNAs with chemical modification for prime editing |
| WO2023049728A1 (en) * | 2021-09-21 | 2023-03-30 | Pairwise Plants Services, Inc. | Color-based and/or visual methods for identifying the presence of a transgene and compositions and constructs relating to the same |
| CN114369677A (zh) * | 2022-01-04 | 2022-04-19 | 江汉大学 | 一种检测小麦转基因成分和转基因品系的引物组合、试剂盒、检测方法及应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ526507A (en) * | 2001-01-26 | 2005-07-29 | Commw Scient Ind Res Org | Methods and means for producing efficient silencing construct using recombinational cloning |
| US20030232410A1 (en) * | 2002-03-21 | 2003-12-18 | Monika Liljedahl | Methods and compositions for using zinc finger endonucleases to enhance homologous recombination |
| WO2008021207A2 (en) * | 2006-08-11 | 2008-02-21 | Dow Agrosciences Llc | Zinc finger nuclease-mediated homologous recombination |
| CA2689345C (en) * | 2007-06-05 | 2017-07-11 | Bayer Bioscience N.V. | Methods and means for exact replacement of target dna in eukaryotic organisms |
| CN106995819B (zh) * | 2008-07-01 | 2020-10-20 | 孟山都技术公司 | 用于调控靶基因表达的重组dna构建体和方法 |
| SI2370575T1 (en) * | 2008-12-17 | 2018-07-31 | Dow Agrosciences, Llc | Targeted integration in the Zp15 locus |
| DE112010001772T5 (de) * | 2009-03-20 | 2012-10-18 | Basf Plant Science Company Gmbh | Nematodenresistente transgene pflanzen |
| JP2013517774A (ja) | 2010-01-22 | 2013-05-20 | ダウ アグロサイエンシィズ エルエルシー | 遺伝子改変生物における導入遺伝子の切除 |
| HUE033500T2 (en) * | 2010-01-22 | 2017-12-28 | Dow Agrosciences Llc | Engineered landing pads for gene targeting in plants |
| EP2580336B1 (en) | 2010-06-09 | 2017-05-10 | Bayer CropScience NV | Methods and means to modify a plant genome at a nucleotide sequence commonly used in plant genome engineering |
| EP2729567B1 (en) | 2011-07-08 | 2016-10-05 | Cellectis | Method for increasing the efficiency of double-strand break-induced mutagenssis |
| AU2014315335B2 (en) * | 2013-09-04 | 2017-08-24 | Corteva Agriscience Llc | Rapid targeting analysis in crops for determining donor insertion |
-
2014
- 2014-11-03 AU AU2014341928A patent/AU2014341928B2/en not_active Ceased
- 2014-11-03 KR KR1020167014602A patent/KR102248730B1/ko not_active Expired - Fee Related
- 2014-11-03 RU RU2016122038A patent/RU2687369C2/ru active
- 2014-11-03 AR ARP140104120A patent/AR098283A1/es unknown
- 2014-11-03 CN CN201480060417.5A patent/CN105683357B/zh not_active Expired - Fee Related
- 2014-11-03 US US14/531,710 patent/US10077449B2/en not_active Expired - Fee Related
- 2014-11-03 TW TW103138081A patent/TWI669395B/zh not_active IP Right Cessation
- 2014-11-03 JP JP2016526812A patent/JP6560203B2/ja not_active Expired - Fee Related
- 2014-11-03 WO PCT/US2014/063732 patent/WO2015066637A1/en not_active Ceased
- 2014-11-03 BR BR102014027448A patent/BR102014027448A8/pt not_active Application Discontinuation
- 2014-11-03 EP EP14858498.0A patent/EP3066192B1/en not_active Not-in-force
- 2014-11-03 CA CA2926534A patent/CA2926534A1/en not_active Abandoned
-
2016
- 2016-03-18 ZA ZA2016/01929A patent/ZA201601929B/en unknown
- 2016-04-25 IL IL245313A patent/IL245313B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN105683357A (zh) | 2016-06-15 |
| KR102248730B1 (ko) | 2021-05-07 |
| IL245313B (en) | 2019-05-30 |
| CA2926534A1 (en) | 2015-05-07 |
| US10077449B2 (en) | 2018-09-18 |
| US20150143588A1 (en) | 2015-05-21 |
| WO2015066637A1 (en) | 2015-05-07 |
| TWI669395B (zh) | 2019-08-21 |
| IL245313A0 (en) | 2016-06-30 |
| JP2016534727A (ja) | 2016-11-10 |
| KR20160079090A (ko) | 2016-07-05 |
| AU2014341928A1 (en) | 2016-04-07 |
| EP3066192A1 (en) | 2016-09-14 |
| AR098283A1 (es) | 2016-05-26 |
| TW201522630A (zh) | 2015-06-16 |
| EP3066192B1 (en) | 2019-05-01 |
| BR102014027448A8 (pt) | 2021-08-24 |
| RU2687369C2 (ru) | 2019-05-13 |
| CN105683357B (zh) | 2020-10-30 |
| AU2014341928B2 (en) | 2017-11-30 |
| BR102014027448A2 (pt) | 2015-09-15 |
| RU2016122038A (ru) | 2017-12-11 |
| JP6560203B2 (ja) | 2019-08-14 |
| ZA201601929B (en) | 2019-06-26 |
| EP3066192A4 (en) | 2017-07-19 |
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| Date | Code | Title | Description |
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| PD4A | Correction of name of patent owner |