RU2015113523A - Способы и системы для средств планирования экспериментов цифровой пцр - Google Patents
Способы и системы для средств планирования экспериментов цифровой пцр Download PDFInfo
- Publication number
- RU2015113523A RU2015113523A RU2015113523A RU2015113523A RU2015113523A RU 2015113523 A RU2015113523 A RU 2015113523A RU 2015113523 A RU2015113523 A RU 2015113523A RU 2015113523 A RU2015113523 A RU 2015113523A RU 2015113523 A RU2015113523 A RU 2015113523A
- Authority
- RU
- Russia
- Prior art keywords
- experiment
- user
- optimization
- type
- qpcr
- Prior art date
Links
- 238000002474 experimental method Methods 0.000 title claims abstract 62
- 238000000034 method Methods 0.000 title claims abstract 29
- 238000011529 RT qPCR Methods 0.000 claims abstract 38
- 239000012895 dilution Substances 0.000 claims abstract 28
- 238000010790 dilution Methods 0.000 claims abstract 28
- 238000005457 optimization Methods 0.000 claims abstract 24
- 239000012224 working solution Substances 0.000 claims abstract 15
- 238000006243 chemical reaction Methods 0.000 claims abstract 12
- 238000001514 detection method Methods 0.000 claims abstract 12
- 239000011541 reaction mixture Substances 0.000 claims abstract 10
- 239000000758 substrate Substances 0.000 claims abstract 10
- 238000007847 digital PCR Methods 0.000 claims abstract 4
- 108700028369 Alleles Proteins 0.000 claims 1
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Artificial Intelligence (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Evolutionary Computation (AREA)
- Public Health (AREA)
- Software Systems (AREA)
- Bioethics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Testing, Inspecting, Measuring Of Stereoscopic Televisions And Televisions (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261701380P | 2012-09-14 | 2012-09-14 | |
| US61/701,380 | 2012-09-14 | ||
| US201261714137P | 2012-10-15 | 2012-10-15 | |
| US61/714,137 | 2012-10-15 | ||
| US201361758216P | 2013-01-29 | 2013-01-29 | |
| US61/758,216 | 2013-01-29 | ||
| US201361788272P | 2013-03-15 | 2013-03-15 | |
| US61/788,272 | 2013-03-15 | ||
| US201361830507P | 2013-06-03 | 2013-06-03 | |
| US61/830,507 | 2013-06-03 | ||
| PCT/US2013/059815 WO2014043581A1 (en) | 2012-09-14 | 2013-09-13 | Methods and systems for a digital pcr experiment designer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2015113523A true RU2015113523A (ru) | 2016-11-10 |
Family
ID=49305105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015113523A RU2015113523A (ru) | 2012-09-14 | 2013-09-13 | Способы и системы для средств планирования экспериментов цифровой пцр |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10984888B2 (https=) |
| EP (2) | EP2895978A1 (https=) |
| JP (1) | JP2016500856A (https=) |
| KR (1) | KR20150083992A (https=) |
| CN (2) | CN104937600B (https=) |
| AU (1) | AU2013315167A1 (https=) |
| BR (1) | BR112015005702A2 (https=) |
| IN (1) | IN2015DN02987A (https=) |
| RU (1) | RU2015113523A (https=) |
| SG (1) | SG11201502797PA (https=) |
| WO (1) | WO2014043581A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5908886B2 (ja) * | 2010-04-09 | 2016-04-26 | ライフ テクノロジーズ コーポレーション | ｑＰＣＲ遺伝子型決定データ用の視覚化ツール |
| US10612080B2 (en) * | 2014-09-22 | 2020-04-07 | Roche Molecular Systems, Inc. | Digital PCR for non-invasive prenatal testing |
| WO2017205796A2 (en) * | 2016-05-27 | 2017-11-30 | Life Technologies Corporation | Methods and systems for graphical user interfaces for biological data |
| CN106906295B (zh) * | 2017-03-31 | 2020-12-08 | 天津诺禾致源生物信息科技有限公司 | 数字pcr检测基因点突变方法及装置 |
| CN107312850A (zh) * | 2017-07-19 | 2017-11-03 | 华东医药（杭州）基因科技有限公司 | 一种pcr无效扩增的检测方法 |
| CN107784197B (zh) * | 2017-10-27 | 2021-01-19 | 领航基因科技（杭州）有限公司 | 一种pcr实验优化方法 |
| JP7098096B2 (ja) * | 2017-11-07 | 2022-07-11 | 株式会社リコー | 検出精度特定方法、検出精度特定装置、及び検出精度特定プログラム |
| US11198130B2 (en) * | 2018-06-21 | 2021-12-14 | Sharp Life Science (Eu) Limited | EWOD system and methods to increase dynamic range for digital nucleic acid amplification |
| US11060141B1 (en) * | 2019-12-23 | 2021-07-13 | Stilla Technologies | Multiplex drop-off digital polymerase chain reaction methods |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6604092B1 (en) * | 1999-02-26 | 2003-08-05 | Lisa E. Stewart | Expert system utilizing a knowledge base and design of experiment (DOE) techniques |
| US20020037507A1 (en) * | 1999-12-16 | 2002-03-28 | Walkerpeach Cindy R. | Compositions, methods and kits for allele discrimination |
| US6964850B2 (en) * | 2001-11-09 | 2005-11-15 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| DE102005054671A1 (de) * | 2005-11-14 | 2007-05-16 | Deutsche Telekom Ag | Verfahren und Architektur zur Anwendung elektronischer Formulare im medizinischen Bereich |
| CN101052041A (zh) * | 2007-05-10 | 2007-10-10 | 浙江大学 | 医疗信息系统集成引擎 |
| US9487822B2 (en) | 2008-03-19 | 2016-11-08 | Fluidigm Corporation | Method and apparatus for determining copy number variation using digital PCR |
| EP2307577B1 (en) * | 2008-06-25 | 2015-06-03 | Life Technologies Corporation | Methods for measuring analytes using large scale fet arrays |
| EP3663411B1 (en) | 2008-08-12 | 2021-11-24 | Stokes Bio Limited | Methods for digital pcr |
| US8285734B2 (en) * | 2008-10-29 | 2012-10-09 | International Business Machines Corporation | Comparison of documents based on similarity measures |
| CN101452503A (zh) * | 2008-11-28 | 2009-06-10 | 上海生物信息技术研究中心 | 一种异构临床医疗信息共享系统和方法 |
| CN102191314A (zh) * | 2010-03-12 | 2011-09-21 | 孙朝辉 | 一种基于pcr的低成本、简单、高效的snp检测方法 |
| CN101880719B (zh) * | 2010-07-16 | 2012-09-05 | 中国水产科学研究院黄海水产研究所 | 大菱鲆亲子鉴定的微卫星多重pcr方法 |
| CN102140541B (zh) * | 2011-02-15 | 2012-11-21 | 北京林业大学 | 一种香石竹四种病毒的同步检测方法 |
| CN102654891B (zh) * | 2011-03-03 | 2015-08-12 | 深圳市智慧健康产业发展有限公司 | 一种覆盖社区和家庭的健康管理系统 |
| CN102321624A (zh) * | 2011-08-30 | 2012-01-18 | 天津农学院 | 革胡子鲶生长激素基因表达定量pcr分析中用于内参基因扩增的引物序列 |
-
2013
- 2013-09-13 WO PCT/US2013/059815 patent/WO2014043581A1/en not_active Ceased
- 2013-09-13 SG SG11201502797PA patent/SG11201502797PA/en unknown
- 2013-09-13 KR KR1020157009139A patent/KR20150083992A/ko not_active Withdrawn
- 2013-09-13 EP EP13773921.5A patent/EP2895978A1/en not_active Ceased
- 2013-09-13 IN IN2987DEN2015 patent/IN2015DN02987A/en unknown
- 2013-09-13 US US14/428,312 patent/US10984888B2/en active Active
- 2013-09-13 EP EP22152064.6A patent/EP4044188A1/en not_active Withdrawn
- 2013-09-13 CN CN201380052860.3A patent/CN104937600B/zh active Active
- 2013-09-13 CN CN201711318728.9A patent/CN108229104B/zh not_active Expired - Fee Related
- 2013-09-13 BR BR112015005702A patent/BR112015005702A2/pt not_active Application Discontinuation
- 2013-09-13 AU AU2013315167A patent/AU2013315167A1/en not_active Abandoned
- 2013-09-13 RU RU2015113523A patent/RU2015113523A/ru not_active Application Discontinuation
- 2013-09-13 JP JP2015532109A patent/JP2016500856A/ja not_active Withdrawn
-
2021
- 2021-03-19 US US17/207,488 patent/US20210313010A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN108229104B (zh) | 2022-06-10 |
| AU2013315167A1 (en) | 2015-04-30 |
| CN104937600B (zh) | 2018-01-16 |
| US20210313010A1 (en) | 2021-10-07 |
| KR20150083992A (ko) | 2015-07-21 |
| BR112015005702A2 (pt) | 2017-07-04 |
| CN104937600A (zh) | 2015-09-23 |
| WO2014043581A1 (en) | 2014-03-20 |
| CN108229104A (zh) | 2018-06-29 |
| US10984888B2 (en) | 2021-04-20 |
| IN2015DN02987A (https=) | 2015-09-18 |
| US20150278437A1 (en) | 2015-10-01 |
| JP2016500856A (ja) | 2016-01-14 |
| EP4044188A1 (en) | 2022-08-17 |
| SG11201502797PA (en) | 2015-05-28 |
| EP2895978A1 (en) | 2015-07-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2015113523A (ru) | Способы и системы для средств планирования экспериментов цифровой пцр | |
| Qin et al. | HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data | |
| Anders et al. | Detecting differential usage of exons from RNA-seq data | |
| BR112018015913A2 (pt) | método para determinar uma variação no número de cópia de uma sequência de ácido nucleico de interesse, e, sistema para avaliar o número de cópia de uma sequência de ácido nucleico de interesse. | |
| EP2198293A4 (en) | METHOD AND SYSTEM FOR DETERMINING GENOCOPY VARIANTS | |
| Lin et al. | Genome-wide analysis of prognostic lncRNAs, miRNAs, and mRNAs forming a competing endogenous RNA network in hepatocellular carcinoma | |
| WO2014058987A4 (en) | Systems and methods for tumor clonality analysis | |
| Chan et al. | Improved risk stratification of nasopharyngeal cancer by targeted sequencing of Epstein–Barr virus DNA in post-treatment plasma | |
| RU2013137442A (ru) | Навигационная система и способ разрешения целочисленных неоднозначностей с использованием ограничения неоднозначности двойной разности | |
| CN103930886A (zh) | 使用副本的meta 分析进行真实世界误差的计算 | |
| AU2018289385A1 (en) | Methods for accurate computational decomposition of DNA mixtures from contributors of unknown genotypes | |
| Ylli et al. | Microfluidic droplet digital PCR is a powerful tool for detection of BRAF and TERT mutations in papillary thyroid carcinomas | |
| Pimentel et al. | Keep me around: intron retention detection and analysis | |
| Moon et al. | The clinical significance and molecular features of the spatial tumor shapes in breast cancers | |
| Rasti et al. | Diagnostic and prognostic accuracy of miR-21 in renal cell carcinoma: a systematic review protocol | |
| RU2017131044A (ru) | Способы и системы для экспериментального планирования и анализа | |
| Parker et al. | periscope: sub-genomic RNA identification in SARS-CoV-2 Genomic Sequencing Data | |
| De Fanti et al. | Massive parallel sequencing of human whole mitochondrial genomes with Ion Torrent technology: an optimized workflow for Anthropological and Population Genetics studies | |
| EP3207133B1 (en) | Cross-platform transformation of gene expression data | |
| Karaoglanoglu et al. | Characterization of segmental duplications and large inversions using Linked-Reads | |
| Wang et al. | MicroFisher: Fungal taxonomic classification for metatranscriptomic and metagenomic data using multiple short hypervariable markers | |
| Brooks et al. | Finite sample weighting of recursive forecast errors | |
| Liu et al. | Gene-specific methylation profiles for integrative methylation-expression analysis in cancer research | |
| Nabavi et al. | Analysis of sequence-based copy number variation detection tools for cancer studies | |
| Kittichotirat et al. | Assessment of software for somatic single nucleotide variant identification using simulated whole-genome sequencing data of cancer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20160914 |