RU2014136715A - Водная фармацевтическая композиция с улучшенной стабильностью - Google Patents
Водная фармацевтическая композиция с улучшенной стабильностью Download PDFInfo
- Publication number
- RU2014136715A RU2014136715A RU2014136715A RU2014136715A RU2014136715A RU 2014136715 A RU2014136715 A RU 2014136715A RU 2014136715 A RU2014136715 A RU 2014136715A RU 2014136715 A RU2014136715 A RU 2014136715A RU 2014136715 A RU2014136715 A RU 2014136715A
- Authority
- RU
- Russia
- Prior art keywords
- pharmaceutical composition
- composition according
- agent
- emedastine
- olopatadine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261597416P | 2012-02-10 | 2012-02-10 | |
| US61/597,416 | 2012-02-10 | ||
| PCT/US2013/025376 WO2013119974A1 (en) | 2012-02-10 | 2013-02-08 | Aqueous pharmaceutical composition with enhanced stability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2014136715A true RU2014136715A (ru) | 2016-03-27 |
Family
ID=47750831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2014136715A RU2014136715A (ru) | 2012-02-10 | 2013-02-08 | Водная фармацевтическая композиция с улучшенной стабильностью |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20130210812A1 (https=) |
| EP (1) | EP2811979B1 (https=) |
| JP (1) | JP6180443B2 (https=) |
| KR (1) | KR102047954B1 (https=) |
| CN (1) | CN104168885A (https=) |
| AU (1) | AU2013216847B2 (https=) |
| BR (1) | BR112014019742A8 (https=) |
| CA (1) | CA2864165A1 (https=) |
| MX (1) | MX356050B (https=) |
| RU (1) | RU2014136715A (https=) |
| TW (1) | TW201336527A (https=) |
| WO (1) | WO2013119974A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10744153B1 (en) * | 2019-07-01 | 2020-08-18 | Cloudbreak Therapeutics Llc | Compositions and methods for treating meibomian gland dysfunction |
| WO2025137749A1 (pt) * | 2023-12-27 | 2025-07-03 | Eurofarma Laboratórios S.A. | Processo de solubilização de olopatadina e seu uso |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4027020A (en) | 1974-10-29 | 1977-05-31 | Millmaster Onyx Corporation | Randomly terminated capped polymers |
| US3931319A (en) | 1974-10-29 | 1976-01-06 | Millmaster Onyx Corporation | Capped polymers |
| US4525346A (en) | 1981-09-28 | 1985-06-25 | Alcon Laboratories, Inc. | Aqueous antimicrobial ophthalmic solutions |
| US4407791A (en) | 1981-09-28 | 1983-10-04 | Alcon Laboratories, Inc. | Ophthalmic solutions |
| US4836986A (en) | 1984-09-28 | 1989-06-06 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| JPS6310784A (ja) | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
| US5037647A (en) | 1988-09-15 | 1991-08-06 | Alcon Laboratories, Inc. | Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride |
| US5145643A (en) | 1990-01-05 | 1992-09-08 | Allergan, Inc. | Nonoxidative ophthalmic compositions and methods for preserving and using same |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5300287A (en) | 1992-11-04 | 1994-04-05 | Alcon Laboratories, Inc. | Polymeric antimicrobials and their use in pharmaceutical compositions |
| GB9711643D0 (en) * | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| EP0889056B1 (en) | 1997-07-01 | 2006-04-12 | Pfizer Products Inc. | Process for making a cyclodextrin |
| DE69839355T2 (de) * | 1997-07-29 | 2009-06-04 | Alcon Laboratories, Inc., Fort Worth | Ophthalmische Zusammensetzungen enthaltend Galaktomannanpolymere und Borat |
| US6375973B2 (en) * | 2000-01-25 | 2002-04-23 | Alcon Universal Ltd. | Ophthalmic anti-allergy compositions suitable for use with contact lenses |
| MXPA04008171A (es) * | 2002-02-22 | 2004-11-26 | Pharmacia Corp | Formulacion oftalmica con sistema de goma. |
| US20040198828A1 (en) * | 2003-01-17 | 2004-10-07 | Abelson Mark B. | Combinational use of long-acting and short-acting anti-histamines for ocular allergies |
| WO2008015695A2 (en) * | 2006-05-15 | 2008-02-07 | Sun Pharmaceutical Industries Limited | Inclusion complex of olopatadine and cyclodextrin |
| TWI434926B (zh) | 2006-12-11 | 2014-04-21 | Alcon Res Ltd | 眼用組成物中聚氧化乙烯-聚氧化丁烯（ｐｅｏ-ｐｂｏ）嵌段共聚物之使用 |
| PT2114367E (pt) * | 2007-02-07 | 2016-02-01 | Novartis Ag | Formulações de olopatadina para administração nasal tópica |
| ZA200904917B (en) * | 2007-02-09 | 2010-09-29 | Alcon Inc | Ophthalmic compositions containing a synergistic combination of three polymers |
| AR066901A1 (es) * | 2007-05-18 | 2009-09-23 | Alcon Mfg Ltd | Composiciones fodfolipidicas para elcuidado de lentes de contacto y conservacion de composiciones farmaceuticas |
| US7635773B2 (en) | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
| EP2393837A1 (en) | 2009-02-05 | 2011-12-14 | Alcon Research, Ltd. | Process for purifying guar |
| PH12012501111A1 (en) * | 2009-12-03 | 2016-09-09 | Novartis Ag | Carboxyvinyl polymer-containing nanoparticles suspensions |
| TWI478730B (zh) * | 2009-12-03 | 2015-04-01 | Alcon Res Ltd | 眼科乳劑 |
| CA2798069C (en) * | 2010-05-05 | 2016-07-05 | Howard Allen Ketelson | Stabilized ophthalmic galactomannan formulations |
| WO2011141929A2 (en) * | 2010-05-11 | 2011-11-17 | Cadila Healthcare Limited | Aqueous pharmaceutical compositions of fluticasone and olopatadine |
| TWI544922B (zh) * | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物 |
-
2013
- 2013-02-04 TW TW102104183A patent/TW201336527A/zh unknown
- 2013-02-08 BR BR112014019742A patent/BR112014019742A8/pt not_active IP Right Cessation
- 2013-02-08 WO PCT/US2013/025376 patent/WO2013119974A1/en not_active Ceased
- 2013-02-08 JP JP2014556735A patent/JP6180443B2/ja not_active Expired - Fee Related
- 2013-02-08 US US13/763,023 patent/US20130210812A1/en not_active Abandoned
- 2013-02-08 AU AU2013216847A patent/AU2013216847B2/en not_active Ceased
- 2013-02-08 RU RU2014136715A patent/RU2014136715A/ru not_active Application Discontinuation
- 2013-02-08 CN CN201380014179.XA patent/CN104168885A/zh active Pending
- 2013-02-08 MX MX2014009573A patent/MX356050B/es active IP Right Grant
- 2013-02-08 CA CA2864165A patent/CA2864165A1/en not_active Abandoned
- 2013-02-08 KR KR1020147024529A patent/KR102047954B1/ko not_active Expired - Fee Related
- 2013-02-08 EP EP13706360.8A patent/EP2811979B1/en not_active Not-in-force
-
2014
- 2014-08-25 US US14/468,243 patent/US20140364422A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| TW201336527A (zh) | 2013-09-16 |
| AU2013216847A1 (en) | 2014-09-04 |
| US20130210812A1 (en) | 2013-08-15 |
| MX2014009573A (es) | 2015-04-08 |
| BR112014019742A8 (pt) | 2017-07-11 |
| WO2013119974A1 (en) | 2013-08-15 |
| CA2864165A1 (en) | 2013-08-15 |
| MX356050B (es) | 2018-05-11 |
| KR102047954B1 (ko) | 2019-11-22 |
| CN104168885A (zh) | 2014-11-26 |
| AU2013216847B2 (en) | 2016-06-23 |
| KR20140120932A (ko) | 2014-10-14 |
| US20140364422A1 (en) | 2014-12-11 |
| EP2811979B1 (en) | 2018-05-02 |
| BR112014019742A2 (https=) | 2017-06-20 |
| EP2811979A1 (en) | 2014-12-17 |
| JP2015509933A (ja) | 2015-04-02 |
| JP6180443B2 (ja) | 2017-08-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2013140423A (ru) | Офтальмологическая композиция с высокой концентрацией олопатадина | |
| CY1122122T1 (el) | Υδατικο οφθαλμικο διαλυμα και μεθοδος για τη θεραπευτικη αγωγη συνδρομου ξηρου οφθαλμου | |
| WO2016172712A3 (en) | Ophthalmic composition | |
| CL2008003771A1 (es) | Sistema de administracion de rna de interferencia (rnai) que comprende una molecula de rnai unida a un peptido penetrador de celulas; metodo para tratar o prevenir un trastorno ocular en un paciente. | |
| MY159463A (en) | Method and composition for treating ocular hypertension and glaucoma | |
| BR112015018252A2 (pt) | composição farmacêutica aquosa de dose fixa estável para administração nasal para um ser humano, composição de suspensão aquosa farmacêutica de dose fixa estável para administração nasal para um ser humano, suspensão estável adequada para administração nasal a um ser humano, método para tratar rinite em um ser humano necessitando do mesmo, uso da composição farmacêutica para administração nasal, método para liberar uma composição farmacêutica e kit | |
| EA200870396A1 (ru) | Лечение аллергических заболеваний глаз | |
| EA201491771A1 (ru) | Офтальмологический раствор, содержащий диквафасол | |
| MX2015002239A (es) | Formulacion oftalmica de lipido polioxilo o de acido graso polioxilo y tratamiento de padecimientos oculares. | |
| EP3069720A8 (en) | Pharmaceutical composition containing glutarimide derivatives, and application thereof for treating eosinophilic diseases | |
| EA201692402A1 (ru) | Лекарственные формы для местного применения и их использование | |
| CY1121841T1 (el) | Τοπικη αντιμυκητιασικη συνθεση για τη θεραπεια της ονυχομυκητιασης | |
| MX2021007161A (es) | Agente que contiene acido ursodesoxicolico para tratar o prevenir la presbicia. | |
| UA113749C2 (xx) | Композиція для назального застосування з покращеною стабільністю | |
| RU2014136715A (ru) | Водная фармацевтическая композиция с улучшенной стабильностью | |
| AR072399A1 (es) | Metodos y dispositivos oftalmicos utilizados en el tratamiento de alergias oculares | |
| MX2015012716A (es) | Composiciones para el uso en el tratamiento de trastornos oculares que usan dipiridamol. | |
| BR112017014016A2 (pt) | método de redução da pressão intraocular, e, composição farmacêutica. | |
| EA201600469A1 (ru) | Фармацевтический препарат для профилактики и лечения прогрессирующей близорукости | |
| EP3295932A3 (en) | Stable odf composition containing hardly soluble therapeutic agent | |
| BR112013033060A2 (pt) | solução oftálmica contendo ácido hialurônico ou sal deste e propileno glicol | |
| EA201200249A1 (ru) | Прасугрел в некристаллической форме и содержащая его фармацевтическая композиция | |
| JP2015509933A5 (https=) | ||
| RU2013152013A (ru) | Офтальмологическая композиция с системой увеличения вязкости, имеющей два различных увеличивающих вязкость агента | |
| MX358604B (es) | Composicion liquida acuosa que contiene acido 2-amino-3-(4-bromobenzoil) fenilacetico. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20170919 |