RU2014129758A - Ионные силиконовые гидрогели с улучшенной гидролитической стабильностью - Google Patents
Ионные силиконовые гидрогели с улучшенной гидролитической стабильностью Download PDFInfo
- Publication number
- RU2014129758A RU2014129758A RU2014129758A RU2014129758A RU2014129758A RU 2014129758 A RU2014129758 A RU 2014129758A RU 2014129758 A RU2014129758 A RU 2014129758A RU 2014129758 A RU2014129758 A RU 2014129758A RU 2014129758 A RU2014129758 A RU 2014129758A
- Authority
- RU
- Russia
- Prior art keywords
- contact lens
- acid
- group
- lysozyme
- absorbs
- Prior art date
Links
- 229920001296 polysiloxane Polymers 0.000 title claims abstract 7
- 239000000017 hydrogel Substances 0.000 title 1
- 230000003301 hydrolyzing effect Effects 0.000 title 1
- 102000016943 Muramidase Human genes 0.000 claims abstract 10
- 108010014251 Muramidase Proteins 0.000 claims abstract 10
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 claims abstract 10
- 235000010335 lysozyme Nutrition 0.000 claims abstract 10
- 239000004325 lysozyme Substances 0.000 claims abstract 10
- 229960000274 lysozyme Drugs 0.000 claims abstract 10
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims abstract 8
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims abstract 8
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 6
- 102000004169 proteins and genes Human genes 0.000 claims abstract 6
- 108090000623 proteins and genes Proteins 0.000 claims abstract 6
- JAHNSTQSQJOJLO-UHFFFAOYSA-N 2-(3-fluorophenyl)-1h-imidazole Chemical compound FC1=CC=CC(C=2NC=CN=2)=C1 JAHNSTQSQJOJLO-UHFFFAOYSA-N 0.000 claims abstract 4
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims abstract 4
- 239000001530 fumaric acid Substances 0.000 claims abstract 4
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims abstract 4
- 239000011976 maleic acid Substances 0.000 claims abstract 4
- LVHBHZANLOWSRM-UHFFFAOYSA-N methylenebutanedioic acid Natural products OC(=O)CC(=C)C(O)=O LVHBHZANLOWSRM-UHFFFAOYSA-N 0.000 claims abstract 4
- 102000019298 Lipocalin Human genes 0.000 claims abstract 3
- 108050006654 Lipocalin Proteins 0.000 claims abstract 3
- GMTNDFOYCWDRQS-WCCKRBBISA-N (2s)-2-(ethenoxycarbonylamino)propanoic acid;3-(ethenoxycarbonylamino)propanoic acid Chemical compound OC(=O)[C@H](C)NC(=O)OC=C.OC(=O)CCNC(=O)OC=C GMTNDFOYCWDRQS-WCCKRBBISA-N 0.000 claims abstract 2
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 claims abstract 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims abstract 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract 2
- XUDBVJCTLZTSDC-UHFFFAOYSA-N 2-ethenylbenzoic acid Chemical compound OC(=O)C1=CC=CC=C1C=C XUDBVJCTLZTSDC-UHFFFAOYSA-N 0.000 claims abstract 2
- WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 claims abstract 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims abstract 2
- 125000002843 carboxylic acid group Chemical group 0.000 claims abstract 2
- 229930016911 cinnamic acid Natural products 0.000 claims abstract 2
- 235000013985 cinnamic acid Nutrition 0.000 claims abstract 2
- 229920001577 copolymer Polymers 0.000 claims abstract 2
- LDHQCZJRKDOVOX-NSCUHMNNSA-N crotonic acid Chemical compound C\C=C\C(O)=O LDHQCZJRKDOVOX-NSCUHMNNSA-N 0.000 claims abstract 2
- 229920001519 homopolymer Polymers 0.000 claims abstract 2
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 claims abstract 2
- 238000006116 polymerization reaction Methods 0.000 claims abstract 2
- LDHQCZJRKDOVOX-UHFFFAOYSA-N trans-crotonic acid Natural products CC=CC(O)=O LDHQCZJRKDOVOX-UHFFFAOYSA-N 0.000 claims abstract 2
- -1 monomethacryloxypropyl Chemical group 0.000 claims 9
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 3
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 3
- 229920006294 polydialkylsiloxane Polymers 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000000203 mixture Chemical group 0.000 claims 1
- REOJLIXKJWXUGB-UHFFFAOYSA-N mofebutazone Chemical group O=C1C(CCCC)C(=O)NN1C1=CC=CC=C1 REOJLIXKJWXUGB-UHFFFAOYSA-N 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
- C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
- C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
- C08F20/04—Acids, Metal salts or ammonium salts thereof
- C08F20/06—Acrylic acid; Methacrylic acid; Metal salts or ammonium salts thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F22/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides or nitriles thereof
- C08F22/10—Esters
- C08F22/12—Esters of phenols or saturated alcohols
- C08F22/16—Esters having free carboxylic acid groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
- C08F290/061—Polyesters; Polycarbonates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
- C08F290/068—Polysiloxanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F30/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal
- C08F30/04—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal
- C08F30/08—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing silicon
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Eyeglasses (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Silicon Polymers (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
1. Контактная линза, образованная путем полимеризации компонентов, в состав которой входит по меньшей мере один силиконсодержащий компонент и по меньшей мере один ионный компонент, содержащий по меньшей мере одну группу карбоновой кислоты в концентрации вплоть до приблизительно 9,3 ммоль/100 г, при этом указанная контактная линза абсорбирует по меньшей мере приблизительно 10 мкг лизоцима, менее приблизительно 5 мкг липокалина, и по меньшей мере 50% всех белков, абсорбированных в или на поверхности указанной контактной линзы, находится в нативной форме.2. Контактная линза по п. 1, в которой указанный ионный компонент содержит по меньшей мере одну способную к полимеризации группу и от трех до десяти атомов углерода.3. Контактная линза по п. 2, в которой указанный ионный компонент содержит от трех до восьми атомов углерода.4. Контактная линза по п. 1, в которой указанный ионный компонент выбирается из группы, включающей акриловую кислоту, метакриловую кислоту, фумаровую кислоту, малеиновую кислоту, итаконовую кислоту, кротоновую кислоту, коричную кислоту, винилбензойную кислоту, моноэфиры фумаровой кислоты, малеиновой кислоты, итаконовой кислоты и N-винилоксикарбонилаланина (N-винилоксикарбонил-β-аланина), а также их гомополимеры и сополимеры.5. Контактная линза по п. 1, в которой указанная контактная линза абсорбирует по меньшей мере приблизительно 50 мкг лизоцима.6. Контактная линза по п. 1, в которой указанная контактная линза абсорбирует по меньшей мере приблизительно 100 мкг лизоцима.7. Контактная линза по п. 1, в которой указанная контактная линза абсорбирует по меньшей мере приблизительно 200 мкг лизоцима.8. Контактная линза по п. 1, в которой указанная контактная линза аб
Claims (20)
1. Контактная линза, образованная путем полимеризации компонентов, в состав которой входит по меньшей мере один силиконсодержащий компонент и по меньшей мере один ионный компонент, содержащий по меньшей мере одну группу карбоновой кислоты в концентрации вплоть до приблизительно 9,3 ммоль/100 г, при этом указанная контактная линза абсорбирует по меньшей мере приблизительно 10 мкг лизоцима, менее приблизительно 5 мкг липокалина, и по меньшей мере 50% всех белков, абсорбированных в или на поверхности указанной контактной линзы, находится в нативной форме.
2. Контактная линза по п. 1, в которой указанный ионный компонент содержит по меньшей мере одну способную к полимеризации группу и от трех до десяти атомов углерода.
3. Контактная линза по п. 2, в которой указанный ионный компонент содержит от трех до восьми атомов углерода.
4. Контактная линза по п. 1, в которой указанный ионный компонент выбирается из группы, включающей акриловую кислоту, метакриловую кислоту, фумаровую кислоту, малеиновую кислоту, итаконовую кислоту, кротоновую кислоту, коричную кислоту, винилбензойную кислоту, моноэфиры фумаровой кислоты, малеиновой кислоты, итаконовой кислоты и N-винилоксикарбонилаланина (N-винилоксикарбонил-β-аланина), а также их гомополимеры и сополимеры.
5. Контактная линза по п. 1, в которой указанная контактная линза абсорбирует по меньшей мере приблизительно 50 мкг лизоцима.
6. Контактная линза по п. 1, в которой указанная контактная линза абсорбирует по меньшей мере приблизительно 100 мкг лизоцима.
7. Контактная линза по п. 1, в которой указанная контактная линза абсорбирует по меньшей мере приблизительно 200 мкг лизоцима.
8. Контактная линза по п. 1, в которой указанная контактная линза абсорбирует по меньшей мере приблизительно 500 мкг лизоцима.
9. Контактная линза по п. 1, в которой указанная контактная линза абсорбирует по меньшей мере приблизительно 800 мкг лизоцима.
10. Контактная линза по п. 1, в которой указанная контактная линза абсорбирует приблизительно 3 мкг или менее липокалина.
11. Контактная линза по п. 1, в которой по меньшей мере 60% всех белков, абсорбированных в или на поверхности указанной контактной линзы, находится в нативной форме.
12. Контактная линза по п. 1, в которой по меньшей мере 75% всех белков, абсорбированных в или на поверхности указанной контактной линзы, находится в нативной форме.
13. Контактная линза по п. 1, дополнительно имеющая содержание воды по меньшей мере приблизительно 15%.
14. Контактная линза по п. 1, дополнительно обеспечивающая угол смачивания менее чем приблизительно 90°.
15. Контактная линза по п. 14, в которой по меньшей мере 60% всех белков, абсорбированных в или на поверхности указанной контактной линзы, находится в нативной форме.
16. Контактная линза по п. 14, в которой по меньшей мере 75% всех белков, абсорбированных в или на поверхности указанной контактной линзы, находится в нативной форме.
17. Контактная линза по п. 1, в которой указанный по меньшей мере один силиконсодержащий компонент выбирается из соединений формулы I:
где b находится в диапазоне от 2 до 20; по меньшей мере одна концевая группа R1 представляет собой моновалентную реакционноспособную группу, а другая концевая группа R1 представляет собой моновалентную реакционноспособную группу или моновалентную алкильную группу, содержащую 1-16 атомов углерода, и остальные группы R1 независимо выбираются из моновалентных алкильных групп, содержащих 1-16 атомов углерода.
18. Контактная линза по п. 1, в которой указанный по меньшей мере один силиконсодержащий компонент выбирается из группы, включающей полидиалкилсилоксан с концевыми монометакрилоксипропильной и моно-н-алкильной группами, бис-3-акрилокси-2-гидроксипропилоксипропилполидиалкилсилоксан, полидиалкилсилоксан с концевой метакрилоксипропильной группой, полидиалкилсилоксан с концевыми моно-(3-метакрилокси-2-гидроксипропилокси)пропильной и моноалкильной группами, а также их сочетания.
19. Контактная линза по п. 1, в которой указанный по меньшей мере один силиконсодержащий компонент выбирается из группы, включающей полидиметилсилоксан с концевыми монометакрилоксипропильной и моно-н-C1-4 алкильной группами, бис-3-акрилокси-2-гидроксипропилоксипропилполидиалкилсилоксан и полидиалкилсилоксан с концевыми моно-(3-метакрилокси-2-гидроксипропилокси)пропильной и моно-C1-4 алкильной группами, а также их сочетания.
20. Контактная линза по п. 1, в которой указанный по меньшей мере один силиконсодержащий компонент выбирается из группы, включающей полидиметилсилоксан с концевыми монометакрилоксипропильной и моно-н-бутильной группами, бис-3-акрилокси-2-гидроксипропилоксипропилполидиметилсилоксан, полидиметилсилоксан с концевой метакрилоксипропильной группой и полидиметилсилоксан с концевыми моно-(3-метакрилокси-2-гидроксипропилокси)пропильной и монобутильной группами, а также их смеси.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10145508P | 2008-09-30 | 2008-09-30 | |
| US61/101,455 | 2008-09-30 | ||
| US12/567,352 | 2009-09-25 | ||
| US12/567,352 US8470906B2 (en) | 2008-09-30 | 2009-09-25 | Ionic silicone hydrogels having improved hydrolytic stability |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011117556/04A Division RU2528631C2 (ru) | 2008-09-30 | 2009-09-28 | Ионные силиконовые гидрогели с улучшенной гидролитической стабильностью |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2014129758A true RU2014129758A (ru) | 2016-02-10 |
| RU2634616C2 RU2634616C2 (ru) | 2017-11-02 |
| RU2634616C9 RU2634616C9 (ru) | 2018-10-04 |
Family
ID=41228660
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011117556/04A RU2528631C2 (ru) | 2008-09-30 | 2009-09-28 | Ионные силиконовые гидрогели с улучшенной гидролитической стабильностью |
| RU2014129758A RU2634616C9 (ru) | 2008-09-30 | 2014-07-18 | Ионные силиконовые гидрогели с улучшенной гидролитической стабильностью |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011117556/04A RU2528631C2 (ru) | 2008-09-30 | 2009-09-28 | Ионные силиконовые гидрогели с улучшенной гидролитической стабильностью |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US8470906B2 (ru) |
| EP (1) | EP2342588B9 (ru) |
| JP (1) | JP5689418B2 (ru) |
| KR (2) | KR101709065B1 (ru) |
| CN (1) | CN102171589B (ru) |
| AR (1) | AR073719A1 (ru) |
| AU (1) | AU2009298732B2 (ru) |
| BR (1) | BRPI0920823A2 (ru) |
| CA (1) | CA2738778C (ru) |
| RU (2) | RU2528631C2 (ru) |
| SG (1) | SG194396A1 (ru) |
| TW (2) | TWI545368B (ru) |
| WO (1) | WO2010039653A1 (ru) |
Families Citing this family (121)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130203812A1 (en) * | 2008-09-30 | 2013-08-08 | Johnson & Johnson Vision Care, Inc. | Ionic silicone hydrogels comprising pharmaceutical and/or nutriceutical components and having improved hydrolytic stability |
| US8470906B2 (en) | 2008-09-30 | 2013-06-25 | Johnson & Johnson Vision Care, Inc. | Ionic silicone hydrogels having improved hydrolytic stability |
| US8877103B2 (en) | 2010-04-13 | 2014-11-04 | Johnson & Johnson Vision Care, Inc. | Process for manufacture of a thermochromic contact lens material |
| US8697770B2 (en) | 2010-04-13 | 2014-04-15 | Johnson & Johnson Vision Care, Inc. | Pupil-only photochromic contact lenses displaying desirable optics and comfort |
| US9522980B2 (en) | 2010-05-06 | 2016-12-20 | Johnson & Johnson Vision Care, Inc. | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same |
| WO2012012184A2 (en) | 2010-06-30 | 2012-01-26 | Johnson & Johnson Vision Care, Inc. | Ophthalmic devices containing chemokine antagonists |
| KR102104222B1 (ko) | 2010-07-30 | 2020-04-24 | 알콘 인코포레이티드 | 수분이 풍부한 표면을 갖는 실리콘 히드로겔 렌즈 |
| US8722076B2 (en) | 2010-09-30 | 2014-05-13 | Surmodics, Inc. | Photochrome- or near IR dye-coupled polymeric matrices for medical articles |
| MY161370A (en) | 2011-02-28 | 2017-04-14 | Coopervision Int Holding Co Lp | Wettable silicon hydrogel contact lenses |
| CA2828418C (en) | 2011-02-28 | 2017-08-29 | Coopervision International Holding Company, Lp | Silicone hydrogel contact lenses and related compositions and methods |
| US9296159B2 (en) | 2011-02-28 | 2016-03-29 | Coopervision International Holding Company, Lp | Silicone hydrogel contact lenses |
| HUE024483T2 (en) | 2011-02-28 | 2016-01-28 | Coopervision Int Holding Co Lp | Size-bearing silicone hydrogel contact lenses |
| EP2681613B1 (en) | 2011-02-28 | 2018-10-24 | CooperVision International Holding Company, LP | Silicone hydrogel contact lenses |
| CN103415789B (zh) | 2011-02-28 | 2017-07-11 | 库柏维景国际控股公司 | 含膦水凝胶隐形眼镜 |
| TWI506334B (zh) | 2011-02-28 | 2015-11-01 | Coopervision Int Holding Co Lp | 具有可接受程度之能量損失的聚矽氧水凝膠隱形眼鏡 |
| US20130203813A1 (en) | 2011-05-04 | 2013-08-08 | Johnson & Johnson Vision Care, Inc. | Medical devices having homogeneous charge density and methods for making same |
| US9170349B2 (en) * | 2011-05-04 | 2015-10-27 | Johnson & Johnson Vision Care, Inc. | Medical devices having homogeneous charge density and methods for making same |
| JP5573784B2 (ja) * | 2011-06-22 | 2014-08-20 | 信越化学工業株式会社 | 両末端グリセロール（メタ）アクリレート変性シリコーン及びその製造方法 |
| JP6017572B2 (ja) | 2011-10-12 | 2016-11-02 | ノバルティス アーゲー | コーティングによるｕｖ吸収性眼用レンズの製造方法 |
| US9125808B2 (en) | 2011-12-23 | 2015-09-08 | Johnson & Johnson Vision Care, Inc. | Ionic silicone hydrogels |
| US9156934B2 (en) | 2011-12-23 | 2015-10-13 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising n-vinyl amides and hydroxyalkyl (meth)acrylates or (meth)acrylamides |
| US8937110B2 (en) | 2011-12-23 | 2015-01-20 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels having a structure formed via controlled reaction kinetics |
| US9588258B2 (en) * | 2011-12-23 | 2017-03-07 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels formed from zero diluent reactive mixtures |
| US8937111B2 (en) * | 2011-12-23 | 2015-01-20 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising desirable water content and oxygen permeability |
| US9140825B2 (en) * | 2011-12-23 | 2015-09-22 | Johnson & Johnson Vision Care, Inc. | Ionic silicone hydrogels |
| US8940812B2 (en) | 2012-01-17 | 2015-01-27 | Johnson & Johnson Vision Care, Inc. | Silicone polymers comprising sulfonic acid groups |
| US20130231260A1 (en) * | 2012-02-17 | 2013-09-05 | NVS Technologies, Inc. | Polymer scaffolds for assay applications |
| US10209534B2 (en) | 2012-03-27 | 2019-02-19 | Johnson & Johnson Vision Care, Inc. | Increased stiffness center optic in soft contact lenses for astigmatism correction |
| US8956682B2 (en) | 2012-04-02 | 2015-02-17 | Surmodics, Inc. | Hydrophilic polymeric coatings for medical articles with visualization moiety |
| US9244196B2 (en) | 2012-05-25 | 2016-01-26 | Johnson & Johnson Vision Care, Inc. | Polymers and nanogel materials and methods for making and using the same |
| US9297929B2 (en) | 2012-05-25 | 2016-03-29 | Johnson & Johnson Vision Care, Inc. | Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers |
| US10073192B2 (en) | 2012-05-25 | 2018-09-11 | Johnson & Johnson Vision Care, Inc. | Polymers and nanogel materials and methods for making and using the same |
| US9555583B1 (en) * | 2012-11-20 | 2017-01-31 | Sandia Corporation | Fabrication of neural interfaces using 3D projection micro-stereolithography |
| US9629945B2 (en) | 2012-12-12 | 2017-04-25 | Surmodics, Inc. | Stilbene-based reactive compounds, polymeric matrices formed therefrom, and articles visualizable by fluorescence |
| HUE031702T2 (en) | 2012-12-17 | 2017-07-28 | Novartis Ag | A method for producing improved UV absorbing ophthalmic lenses |
| US9498035B2 (en) | 2012-12-21 | 2016-11-22 | Coopervision International Holding Company, Lp | Silicone hydrogel contact lenses for sustained release of beneficial polymers |
| US9248928B2 (en) | 2012-12-21 | 2016-02-02 | Coopervision International Holding Company, Lp | Methods of manufacturing contact lenses for delivery of beneficial agents |
| US9568645B2 (en) | 2013-09-30 | 2017-02-14 | Novartis Ag | Silicone hydrogel lenses with relatively-long thermal stability |
| HUE045140T2 (hu) | 2013-09-30 | 2019-12-30 | Novartis Ag | Eljárás UV-abszorbáló szemészeti lencsék elõállítására |
| JP6239099B2 (ja) * | 2013-09-30 | 2017-11-29 | ノバルティス アーゲー | 比較的長期の熱安定性を有するシリコーンヒドロゲルレンズ |
| SG11201603699SA (en) | 2013-12-17 | 2016-07-28 | Novartis Ag | A silicone hydrogel lens with a crosslinked hydrophilic coating |
| WO2016032926A1 (en) | 2014-08-26 | 2016-03-03 | Novartis Ag | Method for applying stable coating on silicone hydrogel contact lenses |
| TWI780873B (zh) * | 2015-09-15 | 2022-10-11 | 星歐光學股份有限公司 | 隱形眼鏡產品 |
| US10449740B2 (en) | 2015-12-15 | 2019-10-22 | Novartis Ag | Method for applying stable coating on silicone hydrogel contact lenses |
| US11125916B2 (en) | 2016-07-06 | 2021-09-21 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising N-alkyl methacrylamides and contact lenses made thereof |
| US10370476B2 (en) | 2016-07-06 | 2019-08-06 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising high levels of polyamides |
| US10371865B2 (en) | 2016-07-06 | 2019-08-06 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising polyamides |
| RU2720005C1 (ru) | 2016-07-06 | 2020-04-23 | Джонсон Энд Джонсон Вижн Кэа, Инк. | Центральная оптическая зона повышенной жесткости в мягких контактных линзах для коррекции астигматизма |
| US11021558B2 (en) | 2016-08-05 | 2021-06-01 | Johnson & Johnson Vision Care, Inc. | Polymer compositions containing grafted polymeric networks and processes for their preparation and use |
| US10676575B2 (en) | 2016-10-06 | 2020-06-09 | Johnson & Johnson Vision Care, Inc. | Tri-block prepolymers and their use in silicone hydrogels |
| WO2018224975A1 (en) | 2017-06-07 | 2018-12-13 | Novartis Ag | Silicone hydrogel contact lenses |
| TWI665263B (zh) | 2017-06-07 | 2019-07-11 | 瑞士商諾華公司 | 矽酮水凝膠接觸鏡片 |
| WO2018224974A1 (en) | 2017-06-07 | 2018-12-13 | Novartis Ag | Method for producing silicone hydrogel contact lenses |
| US10752720B2 (en) | 2017-06-26 | 2020-08-25 | Johnson & Johnson Vision Care, Inc. | Polymerizable blockers of high energy light |
| US10723732B2 (en) | 2017-06-30 | 2020-07-28 | Johnson & Johnson Vision Care, Inc. | Hydroxyphenyl phenanthrolines as polymerizable blockers of high energy light |
| US10526296B2 (en) | 2017-06-30 | 2020-01-07 | Johnson & Johnson Vision Care, Inc. | Hydroxyphenyl naphthotriazoles as polymerizable blockers of high energy light |
| CN117492228A (zh) | 2017-12-13 | 2024-02-02 | 爱尔康公司 | 周抛和月抛水梯度接触镜片 |
| US11034789B2 (en) | 2018-01-30 | 2021-06-15 | Johnson & Johnson Vision Care, Inc. | Ophthalmic devices containing localized grafted networks and processes for their preparation and use |
| US10961341B2 (en) | 2018-01-30 | 2021-03-30 | Johnson & Johnson Vision Care, Inc. | Ophthalmic devices derived from grafted polymeric networks and processes for their preparation and use |
| US20210061934A1 (en) | 2019-08-30 | 2021-03-04 | Johnson & Johnson Vision Care, Inc. | Contact lens displaying improved vision attributes |
| US11993037B1 (en) | 2018-03-02 | 2024-05-28 | Johnson & Johnson Vision Care, Inc. | Contact lens displaying improved vision attributes |
| US10935695B2 (en) | 2018-03-02 | 2021-03-02 | Johnson & Johnson Vision Care, Inc. | Polymerizable absorbers of UV and high energy visible light |
| US11543683B2 (en) | 2019-08-30 | 2023-01-03 | Johnson & Johnson Vision Care, Inc. | Multifocal contact lens displaying improved vision attributes |
| US10996491B2 (en) | 2018-03-23 | 2021-05-04 | Johnson & Johnson Vision Care, Inc. | Ink composition for cosmetic contact lenses |
| US11046636B2 (en) | 2018-06-29 | 2021-06-29 | Johnson & Johnson Vision Care, Inc. | Polymerizable absorbers of UV and high energy visible light |
| US10932902B2 (en) | 2018-08-03 | 2021-03-02 | Johnson & Johnson Vision Care, Inc. | Dynamically tunable apodized multiple-focus opthalmic devices and methods |
| US20200073145A1 (en) | 2018-09-05 | 2020-03-05 | Johnson & Johnson Vision Care, Inc. | Vision care kit |
| US11493668B2 (en) | 2018-09-26 | 2022-11-08 | Johnson & Johnson Vision Care, Inc. | Polymerizable absorbers of UV and high energy visible light |
| US11724471B2 (en) | 2019-03-28 | 2023-08-15 | Johnson & Johnson Vision Care, Inc. | Methods for the manufacture of photoabsorbing contact lenses and photoabsorbing contact lenses produced thereby |
| US11578176B2 (en) | 2019-06-24 | 2023-02-14 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogel contact lenses having non-uniform morphology |
| US11958824B2 (en) | 2019-06-28 | 2024-04-16 | Johnson & Johnson Vision Care, Inc. | Photostable mimics of macular pigment |
| US20200407324A1 (en) | 2019-06-28 | 2020-12-31 | Johnson & Johnson Vision Care, Inc. | Polymerizable fused tricyclic compounds as absorbers of uv and visible light |
| US20210003754A1 (en) | 2019-07-02 | 2021-01-07 | Johnson & Johnson Vision Care, Inc. | Core-shell particles and methods of making and using thereof |
| US11891526B2 (en) | 2019-09-12 | 2024-02-06 | Johnson & Johnson Vision Care, Inc. | Ink composition for cosmetic contact lenses |
| US11360240B2 (en) | 2019-12-19 | 2022-06-14 | Johnson & Johnson Vision Care, Inc. | Contact lens containing photosensitive chromophore and package therefor |
| US20210301088A1 (en) | 2020-03-18 | 2021-09-30 | Johnson & Johnson Vision Care, Inc. | Ophthalmic devices containing transition metal complexes as high energy visible light filters |
| US11853013B2 (en) | 2020-06-15 | 2023-12-26 | Johnson & Johnson Vision Care, Inc. | Systems and methods for indicating the time elapsed since the occurrence of a triggering event |
| US12116443B2 (en) | 2020-06-16 | 2024-10-15 | Johnson & Johnson Vision Care, Inc. | Amino acid-based polymerizable compounds and ophthalmic devices prepared therefrom |
| US20210388141A1 (en) | 2020-06-16 | 2021-12-16 | Johnson & Johnson Vision Care, Inc. | Imidazolium zwitterion polymerizable compounds and ophthalmic devices incorporating them |
| TW202231215A (zh) | 2020-09-14 | 2022-08-16 | 美商壯生和壯生視覺關懷公司 | 單一觸碰式隱形眼鏡盒 |
| TW202225787A (zh) | 2020-09-14 | 2022-07-01 | 美商壯生和壯生視覺關懷公司 | 單指觸動隱形眼鏡包裝 |
| US20220113558A1 (en) | 2020-10-13 | 2022-04-14 | Johnson & Johnson Vision Care, Inc. | Contact lens position and rotation control using the pressure of the eyelid margin |
| JP2024502390A (ja) | 2020-12-13 | 2024-01-19 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド | コンタクトレンズパッケージ及び開封方法 |
| WO2022130089A1 (en) | 2020-12-18 | 2022-06-23 | Johnson & Johnson Vision Care, Inc. | Photostable mimics of macular pigment |
| US12049606B2 (en) | 2021-01-12 | 2024-07-30 | Johnson & Johnson Vision Care, Inc. | Compositions for ophthalmologic devices |
| US12054499B2 (en) | 2021-06-30 | 2024-08-06 | Johnson & Johnson Vision Care, Inc. | Transition metal complexes as visible light absorbers |
| CA3173598A1 (en) | 2021-09-13 | 2023-03-13 | Johnson & Johnson Vision Care, Inc. | Contact lens packages and methods of handling and manufacture |
| US20230176251A1 (en) | 2021-09-29 | 2023-06-08 | Johnson & Johnson Vision Care, Inc. | Ophthalmic lenses and their manufacture by in-mold modification |
| WO2023052890A1 (en) | 2021-09-29 | 2023-04-06 | Johnson & Johnson Vision Care, Inc. | Anthraquinone-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses |
| WO2023052889A1 (en) | 2021-09-29 | 2023-04-06 | Johnson & Johnson Vision Care, Inc. | Amide-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses |
| US11912800B2 (en) | 2021-09-29 | 2024-02-27 | Johnson & Johnson Vision Care, Inc. | Amide-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses |
| US11708209B2 (en) | 2021-11-05 | 2023-07-25 | Johnson & Johnson Vision Care, Inc. | Touchless contact lens packages and methods of handling |
| TW202335928A (zh) | 2021-12-08 | 2023-09-16 | 美商壯生和壯生視覺關懷公司 | 具鏡片升高臂的隱形眼鏡包裝及拿取方法 |
| TW202415312A (zh) | 2021-12-08 | 2024-04-16 | 美商壯生和壯生視覺關懷公司 | 開槽式隱形眼鏡包裝盒及處理方法 |
| EP4448408A1 (en) | 2021-12-13 | 2024-10-23 | Johnson & Johnson Vision Care, Inc. | Contact lens packages with sliding or tilting lens transfer and methods of handling |
| TW202332416A (zh) | 2021-12-14 | 2023-08-16 | 美商壯生和壯生視覺關懷公司 | 具有扭轉或套管桿件的隱形眼鏡包裝及拿取方法 |
| WO2023111852A1 (en) | 2021-12-15 | 2023-06-22 | Johnson & Johnson Vision Care, Inc. | No-touch contact lens packages and methods of handling |
| WO2023111851A1 (en) | 2021-12-15 | 2023-06-22 | Johnson & Johnson Vision Care, Inc. | Solutionless contact lens packages and methods of manufacture |
| TW202337347A (zh) | 2021-12-16 | 2023-10-01 | 美商壯生和壯生視覺關懷公司 | 無觸碰的隱形眼鏡包裝盒及拿取方法 |
| WO2023111939A1 (en) | 2021-12-16 | 2023-06-22 | Johnson & Johnson Vision Care, Inc. | Pressurized or vacuum-sealed contact lens packages |
| KR20240115343A (ko) | 2021-12-17 | 2024-07-25 | 존슨 앤드 존슨 비젼 케어, 인코포레이티드 | 콘택트 렌즈 디스펜서 |
| WO2023111943A1 (en) | 2021-12-17 | 2023-06-22 | Johnson & Johnson Vision Care, Inc. | Contact lens packages having a pivot mechanism and methods of handling |
| US20230296807A1 (en) | 2021-12-20 | 2023-09-21 | Johnson & Johnson Vision Care, Inc. | Contact lenses containing light absorbing regions and methods for their preparation |
| US20230348717A1 (en) | 2022-04-28 | 2023-11-02 | Johnson & Johnson Vision Care, Inc. | Particle surface modification to increase compatibility and stability in hydrogels |
| US11733440B1 (en) | 2022-04-28 | 2023-08-22 | Johnson & Johnson Vision Care, Inc. | Thermally stable nanoparticles and methods thereof |
| US20230350230A1 (en) | 2022-04-28 | 2023-11-02 | Johnson & Johnson Vision Care, Inc. | Using particles for light filtering |
| US20230348718A1 (en) | 2022-04-28 | 2023-11-02 | Johnson & Johnson Vision Care, Inc. | Light-filtering materials for biomaterial integration and methods thereof |
| US11971518B2 (en) | 2022-04-28 | 2024-04-30 | Johnson & Johnson Vision Care, Inc. | Shape engineering of particles to create a narrow spectral filter against a specific portion of the light spectrum |
| TW202419898A (zh) | 2022-06-16 | 2024-05-16 | 美商壯生和壯生視覺關懷公司 | 含有光穩定黃斑色素模擬物及其他可見光濾波物之眼用裝置 |
| US20240099435A1 (en) | 2022-09-27 | 2024-03-28 | Johnson & Johnson Vision Care, Inc. | Flat contact lens packages and methods of handling |
| US12064018B2 (en) | 2022-09-27 | 2024-08-20 | Johnson & Johnson Vision Care, Inc. | Contact lens package with draining port |
| US20240122321A1 (en) | 2022-10-18 | 2024-04-18 | Johnson & Johnson Vision Care, Inc. | Contact lens packages having an absorbent member |
| US20240165019A1 (en) | 2022-11-21 | 2024-05-23 | Bausch + Lomb Ireland Limited | Methods for Treating Eyetear Film Deficiency |
| US20240228466A1 (en) | 2022-12-15 | 2024-07-11 | Johnson & Johnson Vision Care, Inc. | Transition metal complexes as visible light absorbers |
| WO2024134383A1 (en) | 2022-12-21 | 2024-06-27 | Johnson & Johnson Vision Care, Inc. | Compositions for ophthalmologic devices |
| WO2024134384A1 (en) | 2022-12-21 | 2024-06-27 | Johnson & Johnson Vision Care, Inc. | Compositions for ophthalmologic devices |
| WO2024134382A1 (en) | 2022-12-21 | 2024-06-27 | Johnson & Johnson Vision Care, Inc. | Compositions for ophthalmologic devices |
| WO2024134380A1 (en) | 2022-12-21 | 2024-06-27 | Johnson & Johnson Vision Care, Inc. | Compositions for ophthalmologic devices |
| US20240239586A1 (en) | 2023-01-13 | 2024-07-18 | Johnson & Johnson Vision Care, Inc. | Contact lens packages having an absorbent member |
| WO2024194792A1 (en) | 2023-03-20 | 2024-09-26 | Johnson & Johnson Vision Care, Inc. | Ophthalmic lenses and their manufacture by in-mold modification |
| WO2024201156A1 (en) | 2023-03-28 | 2024-10-03 | Johnson & Johnson Vision Care, Inc. | Grafted opthalmic devices containing deactivated regions and processes for their preparation and use |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS108895A (ru) * | 1961-12-27 | |||
| NL128305C (ru) * | 1963-09-11 | |||
| US4113224A (en) * | 1975-04-08 | 1978-09-12 | Bausch & Lomb Incorporated | Apparatus for forming optical lenses |
| US4197266A (en) * | 1974-05-06 | 1980-04-08 | Bausch & Lomb Incorporated | Method for forming optical lenses |
| US4182802A (en) * | 1977-12-27 | 1980-01-08 | Samuel Loshaek | Hydrophilic polymers and contact lenses of high water content |
| US4276402A (en) * | 1979-09-13 | 1981-06-30 | Bausch & Lomb Incorporated | Polysiloxane/acrylic acid/polcyclic esters of methacrylic acid polymer contact lens |
| US4277595A (en) * | 1979-09-13 | 1981-07-07 | Bausch & Lomb Incorporated | Water absorbing contact lenses made from polysiloxane/acrylic acid polymer |
| US4260725A (en) * | 1979-12-10 | 1981-04-07 | Bausch & Lomb Incorporated | Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hydrophilic sidechains |
| US4769431A (en) * | 1984-12-04 | 1988-09-06 | Paragon Optical Inc. | Polyacryloxyalkylsilanol lens composition, articles and method of manufacture |
| US4910277A (en) * | 1988-02-09 | 1990-03-20 | Bambury Ronald E | Hydrophilic oxygen permeable polymers |
| US4810764A (en) * | 1988-02-09 | 1989-03-07 | Bausch & Lomb Incorporated | Polymeric materials with high oxygen permeability and low protein substantivity |
| US5070215A (en) * | 1989-05-02 | 1991-12-03 | Bausch & Lomb Incorporated | Novel vinyl carbonate and vinyl carbamate contact lens material monomers |
| US5314960A (en) * | 1990-04-10 | 1994-05-24 | Permeable Technologies, Inc. | Silicone-containing polymers, oxygen permeable hydrophilic contact lenses and methods for making these lenses and treating patients with visual impairment |
| US5244981A (en) * | 1990-04-10 | 1993-09-14 | Permeable Technologies, Inc. | Silicone-containing contact lens polymers, oxygen permeable contact lenses and methods for making these lenses and treating patients with visual impairment |
| US5371147A (en) * | 1990-10-11 | 1994-12-06 | Permeable Technologies, Inc. | Silicone-containing acrylic star polymers, block copolymers and macromonomers |
| US5158717A (en) * | 1990-11-27 | 1992-10-27 | Bausch & Lomb Incorporated | Method of molding shaped polymeric articles |
| RU2167886C2 (ru) * | 1991-07-05 | 2001-05-27 | Биокомпэтиблз Лимитед. | Полимер, способ получения полимера, поверхность с покрытием, способ покрытия поверхности |
| JP3327471B2 (ja) * | 1991-09-12 | 2002-09-24 | ボシュ アンド ロム インコーポレイテッド | ぬれ性のシリコーンヒドロゲル組成物および方法 |
| US5352714A (en) * | 1991-11-05 | 1994-10-04 | Bausch & Lomb Incorporated | Wettable silicone hydrogel compositions and methods for their manufacture |
| US5260000A (en) * | 1992-08-03 | 1993-11-09 | Bausch & Lomb Incorporated | Process for making silicone containing hydrogel lenses |
| US5944853A (en) * | 1992-10-26 | 1999-08-31 | Johnson & Johnson Vision Products, Inc. | Method for preparing halotriazine dye- and vinyl sulfone dye-monomer compounds |
| US5321108A (en) * | 1993-02-12 | 1994-06-14 | Bausch & Lomb Incorporated | Fluorosilicone hydrogels |
| US5760100B1 (en) * | 1994-09-06 | 2000-11-14 | Ciba Vision Corp | Extended wear ophthalmic lens |
| US5714557A (en) * | 1995-12-07 | 1998-02-03 | Bausch & Lomb Incorporated | Monomeric units useful for reducing the modulus of low water polymeric silicone compositions |
| CA2238650A1 (en) | 1995-12-08 | 1997-06-19 | Novartis Ag | Methods of manufacturing contact lenses |
| FR2750429B1 (fr) * | 1996-06-27 | 1998-08-07 | Essilor Int | Materiau a base de silicone reticule comportant un photoamorceur fixe, son procede de preparation, produit polymerique hydrophile obtenu a partir de ce materiau et son procede de preparation, et nouveaux photoamorceurs |
| US6020445A (en) * | 1997-10-09 | 2000-02-01 | Johnson & Johnson Vision Products, Inc. | Silicone hydrogel polymers |
| US7052131B2 (en) | 2001-09-10 | 2006-05-30 | J&J Vision Care, Inc. | Biomedical devices containing internal wetting agents |
| US6367929B1 (en) * | 1998-03-02 | 2002-04-09 | Johnson & Johnson Vision Care, Inc. | Hydrogel with internal wetting agent |
| US6822016B2 (en) * | 2001-09-10 | 2004-11-23 | Johnson & Johnson Vision Care, Inc. | Biomedical devices containing internal wetting agents |
| US6943203B2 (en) * | 1998-03-02 | 2005-09-13 | Johnson & Johnson Vision Care, Inc. | Soft contact lenses |
| SE9900935D0 (sv) | 1999-03-16 | 1999-03-16 | Pharmacia & Upjohn Bv | Macromolecular compounds |
| KR100522339B1 (ko) * | 1999-12-16 | 2005-10-20 | 아사히 가세이 아이미 가부시끼가이샤 | 장기간 착용이 가능한 소프트 콘택트 렌즈 |
| US6634748B1 (en) * | 2000-11-15 | 2003-10-21 | Johnson & Johnson Vision Care, Inc. | Methods of stabilizing silicone hydrogels against hydrolytic degradation |
| US7879267B2 (en) * | 2001-08-02 | 2011-02-01 | J&J Vision Care, Inc. | Method for coating articles by mold transfer |
| US20050258408A1 (en) * | 2001-12-20 | 2005-11-24 | Molock Frank F | Photochromic contact lenses and methods for their production |
| US8158695B2 (en) | 2002-09-06 | 2012-04-17 | Johnson & Johnson Vision Care, Inc. | Forming clear, wettable silicone hydrogel articles without surface treatments |
| KR100551398B1 (ko) * | 2004-01-03 | 2006-02-09 | 하나광학주식회사 | 기체투과형 하드콘택트렌즈의 제조방법 |
| WO2006095686A1 (ja) * | 2005-03-08 | 2006-09-14 | Dainippon Ink And Chemicals, Inc. | 紫外線硬化性樹脂組成物及び紫外線硬化性塗料及び塗装物 |
| JP4291296B2 (ja) * | 2005-04-08 | 2009-07-08 | 株式会社メニコン | 新規重合性染料およびそれを含む眼用レンズ |
| US20060276608A1 (en) * | 2005-06-06 | 2006-12-07 | Bausch & Lomb Incorporated | Method for making biomedical devices |
| US20070149428A1 (en) * | 2005-12-14 | 2007-06-28 | Bausch & Lomb Incorporated | Method of Packaging a Lens |
| US7960465B2 (en) | 2006-06-30 | 2011-06-14 | Johnson & Johnson Vision Care, Inc. | Antimicrobial lenses, processes to prepare them and methods of their use |
| US20080081850A1 (en) * | 2006-09-29 | 2008-04-03 | Kazuhiko Fujisawa | Process for producing hydrolysis-resistant silicone compounds |
| US7838698B2 (en) * | 2006-09-29 | 2010-11-23 | Johnson & Johnson Vision Care, Inc. | Hydrolysis-resistant silicone compounds |
| US20080102095A1 (en) | 2006-10-31 | 2008-05-01 | Kent Young | Acidic processes to prepare antimicrobial contact lenses |
| GB0623299D0 (en) | 2006-11-22 | 2007-01-03 | Sauflon Cl Ltd | Contact lens |
| CA2672900C (en) * | 2006-12-21 | 2015-02-17 | Johnson & Johnson Vision Care, Inc. | Interferometry testing of lenses, and systems and devices for same |
| BRPI0809271A2 (pt) | 2007-03-22 | 2014-10-14 | Novartis Ag | Pré-polímeros com cadeias pendentes de polímero contendo polissiloxano |
| US8470906B2 (en) | 2008-09-30 | 2013-06-25 | Johnson & Johnson Vision Care, Inc. | Ionic silicone hydrogels having improved hydrolytic stability |
| US8623977B2 (en) * | 2008-11-21 | 2014-01-07 | Hercules Incorporated | Non-hydrocarbyl hydrophobically modified polycarboxylic polymers |
| TWI483996B (zh) | 2009-12-08 | 2015-05-11 | Novartis Ag | 具有共價貼合塗層之聚矽氧水凝膠鏡片 |
| JP5720103B2 (ja) * | 2010-03-18 | 2015-05-20 | 東レ株式会社 | シリコーンハイドロゲル、眼用レンズおよびコンタクトレンズ |
| CA2808462C (en) * | 2010-10-06 | 2016-01-12 | Novartis Ag | Water-processable silicone-containing prepolymers and uses thereof |
| US8587859B2 (en) * | 2011-06-23 | 2013-11-19 | Fuji Xerox Co., Ltd. | White particle for display, particle dispersion for display , display medium, and display device |
-
2009
- 2009-09-25 US US12/567,352 patent/US8470906B2/en active Active
- 2009-09-28 SG SG2013073697A patent/SG194396A1/en unknown
- 2009-09-28 AU AU2009298732A patent/AU2009298732B2/en not_active Ceased
- 2009-09-28 CA CA2738778A patent/CA2738778C/en not_active Expired - Fee Related
- 2009-09-28 WO PCT/US2009/058605 patent/WO2010039653A1/en active Application Filing
- 2009-09-28 KR KR1020167005643A patent/KR101709065B1/ko active IP Right Grant
- 2009-09-28 KR KR1020117009649A patent/KR101607881B1/ko active IP Right Grant
- 2009-09-28 BR BRPI0920823A patent/BRPI0920823A2/pt active Search and Examination
- 2009-09-28 RU RU2011117556/04A patent/RU2528631C2/ru active
- 2009-09-28 CN CN200980139575.9A patent/CN102171589B/zh active Active
- 2009-09-28 JP JP2011529313A patent/JP5689418B2/ja active Active
- 2009-09-28 EP EP09793065.5A patent/EP2342588B9/en active Active
- 2009-09-29 TW TW103140712A patent/TWI545368B/zh active
- 2009-09-29 TW TW098132838A patent/TWI477535B/zh active
- 2009-09-30 AR ARP090103779A patent/AR073719A1/es active IP Right Grant
-
2013
- 2013-05-21 US US13/898,919 patent/US8815972B2/en active Active
-
2014
- 2014-06-11 US US14/301,633 patent/US9260544B2/en active Active
- 2014-07-18 RU RU2014129758A patent/RU2634616C9/ru active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2014129758A (ru) | Ионные силиконовые гидрогели с улучшенной гидролитической стабильностью | |
| EA200900473A1 (ru) | Полупроводящая полиолефиновая композиция | |
| JP5818375B2 (ja) | プラスチック成型体用シロキサニル原料 | |
| HK1150619A1 (en) | Fluoropolymer emulsions | |
| US8586184B2 (en) | Fluorine-containing polymer and aqueous treatment agent | |
| EP1333053A3 (de) | Raumtemperaturvernetzende Einkomponenten-Silikonkautschukformulierungen mit hydrophoben Kieselsäuren | |
| RU2013144740A (ru) | Способ загущения косметической композиции разбухающей в щелочной среде эмульсией полимера, содержащего amps и имеющего высокое содержание акриловой кислоты | |
| ES8406743A1 (es) | Un metodo de fabricar una lente de contacto dura, permeable al oxigeno | |
| JP2008527077A5 (ru) | ||
| JP2015507668A5 (ru) | ||
| RU2009102992A (ru) | Антимикробные линзы, способы их приготовления и способы их применения | |
| RU2013106396A (ru) | Состав защитного покрытия | |
| RU2007123147A (ru) | Композиции, содержащие четырехуглеродные силаны "ласточкин хвост" | |
| ATE446335T1 (de) | Antiblockmittel mit vernetzbarem silicon- enthaltenden polyolefin | |
| JP2007009060A (ja) | 単量体組成物及びコンタクトレンズ | |
| DE60318225D1 (de) | Organosiliciumverbindungen und mischungen zur behandlung von siliciumdioxid | |
| RU2015102143A (ru) | Линза, содержащая низкомолекулярные и высокомолекулярные полиамиды | |
| MY153137A (en) | Altering properties of fuel compositions | |
| TW202035490A (zh) | 有機聚矽氧烷、紫外線固化性矽酮組合物及其固化物 | |
| WO2014159415A1 (en) | Colloidal coomassie stain | |
| TW200641083A (en) | Resin compositions, cured article obtained therefrom, and sheet | |
| ATE530593T1 (de) | Verwendung einer siliziumverbindung als verarbeitungshilfsmittel und als oberflächenglättendes additiv in polyolefinzusammensetzung enthaltend vernetzbares polyolefin mit silangruppen und einen silanol- kondensationskatalysator | |
| EP1867665A3 (en) | Crosslinkable methacrylic resin composition and transparent member | |
| DK0633578T3 (da) | Fast polymerelektrolyt inkluderende en tværbundet polyether omfattende en ionforbindelse og et flydende blødgøringsmiddel | |
| JP4562978B2 (ja) | 固体電解質 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TH4A | Reissue of patent specification | ||
| TK4A | Correction to the publication in the bulletin (patent) |
Free format text: CORRECTION TO CHAPTER -FG4A- IN JOURNAL 31-2017 FOR INID CODE(S) (24) |