RU2013152025A - METHOD FOR PRODUCING 4-SUBSTITUTED THIOMORPHOLINS - Google Patents

METHOD FOR PRODUCING 4-SUBSTITUTED THIOMORPHOLINS Download PDF

Info

Publication number
RU2013152025A
RU2013152025A RU2013152025/04A RU2013152025A RU2013152025A RU 2013152025 A RU2013152025 A RU 2013152025A RU 2013152025/04 A RU2013152025/04 A RU 2013152025/04A RU 2013152025 A RU2013152025 A RU 2013152025A RU 2013152025 A RU2013152025 A RU 2013152025A
Authority
RU
Russia
Prior art keywords
producing
substituted
thiomorpholins
divinyl sulfide
ррh
Prior art date
Application number
RU2013152025/04A
Other languages
Russian (ru)
Other versions
RU2551658C1 (en
Inventor
Внира Рахимовна Ахметова
Ирина Сергеевна Давлетбаева
Василий Михайлович Яныбин
Асхат Габдрахманович Ибрагимов
Усеин Меметович Джемилев
Original Assignee
Федеральное государственное бюджетное учреждение науки Институт нефтехимии и катализа Российской академии наук
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Федеральное государственное бюджетное учреждение науки Институт нефтехимии и катализа Российской академии наук filed Critical Федеральное государственное бюджетное учреждение науки Институт нефтехимии и катализа Российской академии наук
Priority to RU2013152025/04A priority Critical patent/RU2551658C1/en
Application granted granted Critical
Publication of RU2013152025A publication Critical patent/RU2013152025A/en
Publication of RU2551658C1 publication Critical patent/RU2551658C1/en

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Способ получения 4-замещенных тиоморфолинов общей формулы (I):где R=СН(СН), СН, о-, p-СНСН, СНОН, СНСО,отличающийся тем, что дивинилсульфид подвергается взаимодействию с аминосубстратом R-NH[R = указанные выше] в присутствии катализатора РdСl-СFСООН-РРhпри мольном соотношении дивинилсульфид:аминосубстрат:РdСl:СFСООН:РРh=10:10:(0.3-0.7):(1.5-3.5):(0.3-0.7), при 55-65°С и атмосферном давлении в течение 38-42 ч.A method of producing 4-substituted thiomorpholines of the general formula (I): where R = CH (CH), CH, o-, p-CHCH, CHOH, CHCO, characterized in that the divinyl sulfide is reacted with the amino substratum R-NH [R = above ] in the presence of a catalyst РdСl-СFСУН-РРh at a molar ratio divinyl sulfide: aminosubstrate: РdСl: СФСОО: РРh = 10: 10: (0.3-0.7) :( 1.5-3.5) :( 0.3-0.7), at 55-65 ° С and atmospheric pressure for 38-42 hours

Claims (1)

Способ получения 4-замещенных тиоморфолинов общей формулы (I):The method of obtaining 4-substituted thiomorpholines of General formula (I):
Figure 00000001
Figure 00000001
 где R=СН3(СН2)2, С6Н5, о-, p-СН3С6Н4, С2Н4ОН, СН3СО,where R = CH 3 (CH 2 ) 2 , C 6 H 5 , o-, p-CH 3 C 6 H 4 , C 2 H 4 OH, CH 3 CO, отличающийся тем, что дивинилсульфид подвергается взаимодействию с аминосубстратом R-NH2 [R = указанные выше] в присутствии катализатора РdСl2-СF3СООН-РРh3 при мольном соотношении дивинилсульфид:аминосубстрат:РdСl2:СF3СООН:РРh3=10:10:(0.3-0.7):(1.5-3.5):(0.3-0.7), при 55-65°С и атмосферном давлении в течение 38-42 ч. characterized in that divinyl sulfide is reacted with an amino substratum R-NH 2 [R = above] in the presence of a catalyst PdCl 2 -CF 3 COOH-PPh 3 with a molar ratio of divinyl sulfide: aminosubstrate: PdCl 2 : CF 3 COOH: PPh 3 = 10: 10: (0.3-0.7) :( 1.5-3.5) :( 0.3-0.7), at 55-65 ° C and atmospheric pressure for 38-42 hours.
RU2013152025/04A 2013-11-21 2013-11-21 Method for producing 4-substituted thiomorpholines RU2551658C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2013152025/04A RU2551658C1 (en) 2013-11-21 2013-11-21 Method for producing 4-substituted thiomorpholines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2013152025/04A RU2551658C1 (en) 2013-11-21 2013-11-21 Method for producing 4-substituted thiomorpholines

Publications (2)

Publication Number Publication Date
RU2013152025A true RU2013152025A (en) 2015-05-27
RU2551658C1 RU2551658C1 (en) 2015-05-27

Family

ID=53284942

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2013152025/04A RU2551658C1 (en) 2013-11-21 2013-11-21 Method for producing 4-substituted thiomorpholines

Country Status (1)

Country Link
RU (1) RU2551658C1 (en)

Also Published As

Publication number Publication date
RU2551658C1 (en) 2015-05-27

Similar Documents

Publication Publication Date Title
MX2015002616A (en) Synthesis of bis(fluorosulfonyl)imide.
RU2009101579A (en) MONOCER FOR POLYCONDENSATION
CY1118945T1 (en) METHOD AND INTERMEDIATES FOR PREGAMPALIN PREPARATION
RU2010132919A (en) METHOD FOR SELECTIVE OBTAINING α, ω-BIS- (1,3,5-DITIAZINAN-5-IL) -3-OXOPENTANE And α, ω-BIS- (1,3,5-DITIAZINAN-5-IL) -3,6 -DIOXOACTANE
RU2010108950A (en) METHOD FOR PRODUCING 3,7-DIARIL-1,3,5,7-DITIADIAZAOCTANES
EA201270390A1 (en) 1,2,4-TRIAZIN, WHICH CAN BE USED AS AN ACCELERATOR OF VOLCANIZATION AND A METHOD FOR ITS OBTAINING
RU2013152025A (en) METHOD FOR PRODUCING 4-SUBSTITUTED THIOMORPHOLINS
EA201491463A1 (en) METHOD OF OBTAINING A COMPOUND ON A NEW REACTION OF THE MICHAEL ACCESSION WITH THE APPLICATION OF WATER OR DIFFERENT ACIDS AS ADDITIVE
RU2012100111A (en) METHOD FOR PRODUCING 2- AND 2,3-SUBSTITUTED QUINOLINS
RU2012113763A (en) UNSATURATED BLOCK-COPOLESTERSULPHONES
RU2010122542A (en) METHOD FOR PRODUCING MONO- (DI-, TETRA-) METHYL-1,2-BIS- (1,3,5-DITIAZINAN-5-IL) ETHANES
RU2012145638A (en) METHOD FOR PRODUCING 3-Pyridinyl-1,5,3-Dithiazocinanes
RU2012101387A (en) METHOD FOR PRODUCING N- (1,5,3-DITIAZOCINAN-3-IL) AMIDES
RU2012144046A (en) METHOD FOR PRODUCING α, ω- {BIS [(PENTAN-2,4-DION-3-IL) METHYL SULFANIL]} - ALKANOV
RU2010100055A (en) METHOD FOR PRODUCING BIS-2,4-DIALKYL-1,5,3-DITIAZEPAN-3-ILOV
RU2010104331A (en) METHOD FOR PRODUCING BENZYLBUTYL ETHER
RU2008134295A (en) METHOD FOR PRODUCING 1-AMINOMETHYL-ALPHA, OMEGA-ALKADIINS
RU2010123613A (en) METHOD FOR MAGNESIUM FLUORIDE SYNTHESIS
RU2010141245A (en) METHOD FOR PRODUCING METHYL ETHER 2-BENZO [b] FURANCARBOXYLIC ACID
RU2010126714A (en) METHOD FOR PRODUCING 1,4-DIAZABICYCLO [2.1.1] HEXAN
RU2013152020A (en) METHOD FOR PRODUCING (1,5,3-DITIAZEPAN-3-IL) -ALKANDIOLS
RU2012145843A (en) METHOD FOR PRODUCING 3-HETARIL-1,5,3-DITIAZEPINANES
RU2012126441A (en) METHOD FOR PRODUCING 1-HYDROXYADAMANTAN-4-OH (CEMANTANE)
RU2011139925A (en) METHOD FOR PRODUCING N- (1,5,3-DITIAZOCINAN-3-IL) AMIDES
RU2012147376A (en) METHOD FOR PRODUCING 3,3-DI (METHOXICARBONIL) -1,5-DITIACYCLOalkanes

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20151122