RU2012140379A - Способы и композиции для повышения срока выживаемости жирового трансплантата - Google Patents
Способы и композиции для повышения срока выживаемости жирового трансплантата Download PDFInfo
- Publication number
- RU2012140379A RU2012140379A RU2012140379/15A RU2012140379A RU2012140379A RU 2012140379 A RU2012140379 A RU 2012140379A RU 2012140379/15 A RU2012140379/15 A RU 2012140379/15A RU 2012140379 A RU2012140379 A RU 2012140379A RU 2012140379 A RU2012140379 A RU 2012140379A
- Authority
- RU
- Russia
- Prior art keywords
- use according
- erythropoietin
- fat cells
- factor
- per
- Prior art date
Links
- 230000004083 survival effect Effects 0.000 title claims abstract 5
- 239000000203 mixture Substances 0.000 title 1
- 102000003951 Erythropoietin Human genes 0.000 claims abstract 14
- 108090000394 Erythropoietin Proteins 0.000 claims abstract 14
- 229940105423 erythropoietin Drugs 0.000 claims abstract 14
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 claims abstract 14
- 210000001789 adipocyte Anatomy 0.000 claims abstract 12
- 229940126601 medicinal product Drugs 0.000 claims abstract 5
- 230000007547 defect Effects 0.000 claims abstract 4
- 210000004872 soft tissue Anatomy 0.000 claims abstract 4
- 102000015081 Blood Coagulation Factors Human genes 0.000 claims abstract 3
- 108010039209 Blood Coagulation Factors Proteins 0.000 claims abstract 3
- 102000019034 Chemokines Human genes 0.000 claims abstract 3
- 108010012236 Chemokines Proteins 0.000 claims abstract 3
- 102000004127 Cytokines Human genes 0.000 claims abstract 3
- 108090000695 Cytokines Proteins 0.000 claims abstract 3
- 102000004190 Enzymes Human genes 0.000 claims abstract 3
- 108090000790 Enzymes Proteins 0.000 claims abstract 3
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims abstract 3
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims abstract 3
- 150000001413 amino acids Chemical class 0.000 claims abstract 3
- 239000002870 angiogenesis inducing agent Substances 0.000 claims abstract 3
- 230000003115 biocidal effect Effects 0.000 claims abstract 3
- 239000003114 blood coagulation factor Substances 0.000 claims abstract 3
- 150000001720 carbohydrates Chemical class 0.000 claims abstract 3
- OEUUFNIKLCFNLN-LLVKDONJSA-N chembl432481 Chemical compound OC(=O)[C@@]1(C)CSC(C=2C(=CC(O)=CC=2)O)=N1 OEUUFNIKLCFNLN-LLVKDONJSA-N 0.000 claims abstract 3
- 239000000306 component Substances 0.000 claims abstract 3
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract 3
- 210000002744 extracellular matrix Anatomy 0.000 claims abstract 3
- 229930195729 fatty acid Natural products 0.000 claims abstract 3
- 239000000194 fatty acid Substances 0.000 claims abstract 3
- 150000004665 fatty acids Chemical class 0.000 claims abstract 3
- 239000003102 growth factor Substances 0.000 claims abstract 3
- 229940088597 hormone Drugs 0.000 claims abstract 3
- 239000005556 hormone Substances 0.000 claims abstract 3
- 238000002347 injection Methods 0.000 claims abstract 3
- 239000007924 injection Substances 0.000 claims abstract 3
- 150000002500 ions Chemical class 0.000 claims abstract 3
- 239000002858 neurotransmitter agent Substances 0.000 claims abstract 3
- 239000011782 vitamin Substances 0.000 claims abstract 3
- 229940088594 vitamin Drugs 0.000 claims abstract 3
- 229930003231 vitamin Natural products 0.000 claims abstract 3
- 235000013343 vitamin Nutrition 0.000 claims abstract 3
- 150000003722 vitamin derivatives Chemical class 0.000 claims abstract 3
- 206010010356 Congenital anomaly Diseases 0.000 claims abstract 2
- 206010052428 Wound Diseases 0.000 claims abstract 2
- 208000027418 Wounds and injury Diseases 0.000 claims abstract 2
- 208000037919 acquired disease Diseases 0.000 claims abstract 2
- 230000037396 body weight Effects 0.000 claims abstract 2
- 201000011510 cancer Diseases 0.000 claims abstract 2
- 238000001727 in vivo Methods 0.000 claims abstract 2
- 230000036244 malformation Effects 0.000 claims abstract 2
- 238000002278 reconstructive surgery Methods 0.000 claims abstract 2
- 208000017520 skin disease Diseases 0.000 claims abstract 2
- 238000007910 systemic administration Methods 0.000 claims abstract 2
- 210000004027 cell Anatomy 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 1
- 230000000735 allogeneic effect Effects 0.000 claims 1
- 238000011477 surgical intervention Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Surgery (AREA)
- Birds (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30699110P | 2010-02-23 | 2010-02-23 | |
| US61/306,991 | 2010-02-23 | ||
| PCT/IL2011/000181 WO2011104707A1 (en) | 2010-02-23 | 2011-02-23 | Methods and compositions for enhancing fat graft survival |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012140379A true RU2012140379A (ru) | 2014-03-27 |
Family
ID=44506187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012140379/15A RU2012140379A (ru) | 2010-02-23 | 2011-02-23 | Способы и композиции для повышения срока выживаемости жирового трансплантата |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20120315254A1 (https=) |
| EP (1) | EP2539443B1 (https=) |
| JP (2) | JP5823986B2 (https=) |
| CN (1) | CN102906250A (https=) |
| AU (1) | AU2011219425A1 (https=) |
| BR (1) | BR112012021179A2 (https=) |
| CA (1) | CA2790867A1 (https=) |
| IL (1) | IL221619A (https=) |
| IN (1) | IN2012MN02218A (https=) |
| MX (1) | MX2012009768A (https=) |
| RU (1) | RU2012140379A (https=) |
| WO (1) | WO2011104707A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2539443B1 (en) * | 2010-02-23 | 2019-03-27 | Sebana Medical Ltd. | Erythropoietin for use in enhancing fat graft survival |
| JP5953035B2 (ja) * | 2011-11-28 | 2016-07-13 | 学校法人慶應義塾 | 病理診断支援装置、病理診断支援方法、及び病理診断支援プログラム |
| CN107456606A (zh) * | 2017-08-30 | 2017-12-12 | 上海新肌生物科技有限公司 | 一种脂肪细胞存活率提高91%的复活素配方及制备方法 |
| CN110229785A (zh) * | 2019-06-17 | 2019-09-13 | 白晋 | 一种利用血管内皮祖细胞提升脂肪移植成功率的方法 |
| CN111548988B (zh) * | 2020-05-14 | 2023-06-20 | 江苏芝海生物科技有限公司 | 一种医用漂洗液及其制备方法和应用 |
| AU2021388154A1 (en) * | 2020-11-25 | 2023-06-22 | Flagship Pioneering Innovations Vi, Llc | Adipogenic cell compositions and methods |
| CN113413177B (zh) * | 2021-06-23 | 2022-08-02 | 美闺(长沙)医疗美容有限公司 | 一种保持自体脂肪活性的移植设备及控制方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050048035A1 (en) * | 2001-12-07 | 2005-03-03 | Fraser John K. | Methods of using regenerative cells in the treatment of stroke and related diseases and disorders |
| US7651684B2 (en) * | 2001-12-07 | 2010-01-26 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in augmenting autologous fat transfer |
| US7459152B2 (en) * | 2003-04-23 | 2008-12-02 | Rush University Medical Center | Erythropoietin administration to improve graft survival |
| KR101145508B1 (ko) * | 2003-06-18 | 2012-05-15 | 사이토리 테라퓨틱스, 인크. | 자가 지방 이식의 증대에 있어서 지방 조직 유래의 세포를사용하는 방법 |
| ATE469654T1 (de) * | 2003-12-30 | 2010-06-15 | Augustinus Bader | Verwendung des erythropoietins zur regeneration von lebergewebe |
| ITPD20050168A1 (it) * | 2005-06-01 | 2006-12-02 | Fidia Advanced Biopolymers Srl | Formulazioni di acido lipoico ed acido ialuronico e o suoi derivati e loro impiego in campo farmaceutico e cosmetico |
| CA2637663C (en) * | 2006-01-24 | 2015-06-02 | Brown University | Cell aggregation and encapsulation device and method |
| WO2008019434A1 (en) | 2006-08-14 | 2008-02-21 | Victorian Tissue Engineering Pty Ltd | The use of growth factors in a method of improving fat-graft survival |
| WO2009022338A2 (en) * | 2007-08-16 | 2009-02-19 | Saher Hamed | Erythropoietin and fibronectin compositions for therapeutic and cosmetic applications |
| EP2539443B1 (en) * | 2010-02-23 | 2019-03-27 | Sebana Medical Ltd. | Erythropoietin for use in enhancing fat graft survival |
-
2011
- 2011-02-23 EP EP11746961.9A patent/EP2539443B1/en active Active
- 2011-02-23 AU AU2011219425A patent/AU2011219425A1/en not_active Abandoned
- 2011-02-23 WO PCT/IL2011/000181 patent/WO2011104707A1/en not_active Ceased
- 2011-02-23 CN CN2011800205877A patent/CN102906250A/zh active Pending
- 2011-02-23 CA CA2790867A patent/CA2790867A1/en not_active Abandoned
- 2011-02-23 RU RU2012140379/15A patent/RU2012140379A/ru unknown
- 2011-02-23 JP JP2012554466A patent/JP5823986B2/ja active Active
- 2011-02-23 MX MX2012009768A patent/MX2012009768A/es not_active Application Discontinuation
- 2011-02-23 US US13/580,381 patent/US20120315254A1/en active Pending
- 2011-02-23 BR BR112012021179A patent/BR112012021179A2/pt not_active IP Right Cessation
-
2012
- 2012-08-23 IL IL221619A patent/IL221619A/en active IP Right Grant
- 2012-09-20 IN IN2218MUN2012 patent/IN2012MN02218A/en unknown
-
2015
- 2015-10-08 JP JP2015200614A patent/JP6023864B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IN2012MN02218A (https=) | 2015-06-12 |
| CN102906250A (zh) | 2013-01-30 |
| WO2011104707A1 (en) | 2011-09-01 |
| AU2011219425A1 (en) | 2012-10-18 |
| JP2016041261A (ja) | 2016-03-31 |
| EP2539443B1 (en) | 2019-03-27 |
| BR112012021179A2 (pt) | 2015-09-15 |
| EP2539443A1 (en) | 2013-01-02 |
| JP5823986B2 (ja) | 2015-11-25 |
| CA2790867A1 (en) | 2011-09-01 |
| IL221619A (en) | 2017-09-28 |
| JP6023864B2 (ja) | 2016-11-09 |
| EP2539443A4 (en) | 2013-12-11 |
| JP2013520271A (ja) | 2013-06-06 |
| US20120315254A1 (en) | 2012-12-13 |
| MX2012009768A (es) | 2013-02-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022002536A (ja) | 植物及び真菌由来の脱細胞化された細胞壁構造並びに足場材料としてのその使用 | |
| EP3479831B1 (en) | Composition comprising thrombin-treated stem cell-derived exosome for use in treating skin wound | |
| JP7835455B2 (ja) | イオン性自己組織化ペプチド | |
| RU2012140379A (ru) | Способы и композиции для повышения срока выживаемости жирового трансплантата | |
| WO2023072161A1 (zh) | 包含间充质干细胞和水凝胶的组合物及其应用 | |
| CN114404450B (zh) | 一种温敏型干细胞外泌体即型凝胶 | |
| WO2022035778A1 (en) | Delivery of cells and tissues with self-assembling peptide hydrogel materials | |
| KR101583569B1 (ko) | 정맥 투여용 줄기세포 조성물 | |
| JP2013520271A5 (https=) | ||
| JP2018520115A (ja) | 組織病変治療用組成物 | |
| Wang et al. | Stem cells and extracellular vesicles to improve preclinical orofacial soft tissue healing | |
| KR20210021165A (ko) | 지방줄기세포 유래 스페로이드를 포함하는 조건 배지를 유효성분으로 포함하는 상처 치유용 약학 조성물 | |
| CN102614548A (zh) | 一种用于整形美容治疗的干细胞生物制剂 | |
| WO2021169075A1 (zh) | 一种集可注射与抗菌于一体的双功能水凝胶及其制备方法和用途 | |
| ES2377993T3 (es) | Utilización de fracciones celulares del tejido adiposo para la regeneración tisular post-irradiación | |
| KR102250231B1 (ko) | 심혈관 질환 예방 또는 치료용 조성물 | |
| RU2292212C1 (ru) | Кондиционная среда, обладающая лечебным эффектом | |
| CN119096973B (zh) | 一种脱细胞基质及其制备方法和促进生发的用途 | |
| CZ20032011A3 (cs) | Použití nemetabolizovatelného cukru a polymerového absorpčního činidla pro podporu buněčné rekonstrukce a/nebo buněčné diferenciace | |
| JP2008208092A (ja) | 生体再生カプセル | |
| US20250319124A1 (en) | Preparation and use of tissue matrix derived powder | |
| Zadeh et al. | Human Placental Extract: A Multifunctional Biological Agent—Current Status, Challenges and Promising Directions | |
| Laurent et al. | Immune privilege of primary fetal progenitor cells: Optimized safety profile of consistent cell sources for cutaneous and musculoskeletal regenerative medicine | |
| Zhang et al. | Applications of Hydrogels in | |
| KR20250162146A (ko) | 라파마이신을 함유 약물 전달체가 접합된 줄기세포 및 이의 용도 |