RU2009148270A - Молекулы антител человека к il-13 - Google Patents

Молекулы антител человека к il-13 Download PDF

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Publication number
RU2009148270A
RU2009148270A RU2009148270/10A RU2009148270A RU2009148270A RU 2009148270 A RU2009148270 A RU 2009148270A RU 2009148270/10 A RU2009148270/10 A RU 2009148270/10A RU 2009148270 A RU2009148270 A RU 2009148270A RU 2009148270 A RU2009148270 A RU 2009148270A
Authority
RU
Russia
Prior art keywords
group
amino acid
acid sequence
seq
domain
Prior art date
Application number
RU2009148270/10A
Other languages
English (en)
Russian (ru)
Inventor
Филлип Дэвид МОНК (GB)
Филлип Дэвид МОНК
Лутц ДЖЕРМУТУС (GB)
Лутц ДЖЕРМУТУС
Ральф Реймонд МИНТЕР (GB)
Ральф Реймонд Минтер
Силия Патрисиа ШОРРОК (GB)
Силия Патрисиа ШОРРОК
Original Assignee
Кембридж Антибоди Текнолоджи Лимитед (Gb)
Кембридж Антибоди Текнолоджи Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кембридж Антибоди Текнолоджи Лимитед (Gb), Кембридж Антибоди Текнолоджи Лимитед filed Critical Кембридж Антибоди Текнолоджи Лимитед (Gb)
Publication of RU2009148270A publication Critical patent/RU2009148270A/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2009148270/10A 2003-07-15 2009-12-24 Молекулы антител человека к il-13 RU2009148270A (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US48751203P 2003-07-15 2003-07-15
US60/487,512 2003-07-15
US55821604P 2004-03-31 2004-03-31
US60/558,216 2004-03-31
GB0407315.1 2004-03-31
US57379104P 2004-05-24 2004-05-24
US60/573,791 2004-05-24

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU2006104618/13A Division RU2387667C2 (ru) 2003-07-15 2004-07-15 Молекулы антител человека к il-13

Publications (1)

Publication Number Publication Date
RU2009148270A true RU2009148270A (ru) 2011-06-27

Family

ID=44535047

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009148270/10A RU2009148270A (ru) 2003-07-15 2009-12-24 Молекулы антител человека к il-13

Country Status (8)

Country Link
JP (3) JP5519567B2 (fr)
KR (1) KR101073590B1 (fr)
AU (1) AU2011200308B2 (fr)
CY (1) CY1111467T1 (fr)
HK (3) HK1097853A1 (fr)
MX (1) MXPA06000258A (fr)
NO (2) NO338853B1 (fr)
RU (1) RU2009148270A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016027797A2 (pt) * 2014-06-18 2017-10-31 Medimmune Llc métodos e meios de cultura de células compreendendo n-acetilcisteína

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2142860A1 (fr) * 1992-08-21 1994-03-03 Gregorio Aversa Interleukine humaine 13
US20040023337A1 (en) * 2001-10-26 2004-02-05 Heavner George A. IL-13 mutein proteins, antibodies, compositions, methods and uses
JP4723810B2 (ja) * 2001-12-03 2011-07-13 アレクシオン ファーマシューティカルズ， インコーポレイテッド ハイブリッド抗体
WO2003086451A1 (fr) * 2002-04-05 2003-10-23 Centocor, Inc. Proteines derivees de l'immunoglobuline anti il-13 associees a l'asthme, compositions, procedes et utilisations associes
EP1534329A2 (fr) * 2002-08-30 2005-06-01 Glaxo Group Limited VACCIN CONTENANT il-13 ET ADJUVANT
GB0407315D0 (en) * 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
TWI307630B (en) * 2004-07-01 2009-03-21 Glaxo Group Ltd Immunoglobulins

Also Published As

Publication number Publication date
MXPA06000258A (es) 2006-07-03
KR20060054312A (ko) 2006-05-22
KR101073590B1 (ko) 2011-10-14
JP2016047843A (ja) 2016-04-07
NO338853B1 (no) 2016-10-24
CY1111467T1 (el) 2015-08-05
NO342727B1 (no) 2018-07-30
AU2011200308B2 (en) 2011-07-28
JP2011147454A (ja) 2011-08-04
AU2011200308A1 (en) 2011-02-17
HK1216427A1 (zh) 2016-11-11
HK1155185A1 (zh) 2012-05-11
HK1097853A1 (en) 2007-07-06
JP5922686B2 (ja) 2016-05-24
JP5519567B2 (ja) 2014-06-11
JP2014101372A (ja) 2014-06-05
NO20160707A1 (no) 2016-04-27
NO20060730L (no) 2006-04-10

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Legal Events

Date Code Title Description
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20141209