HK1216427A1 - 針對 的人抗體分子 - Google Patents

針對 的人抗體分子

Info

Publication number
HK1216427A1
HK1216427A1 HK16104446.4A HK16104446A HK1216427A1 HK 1216427 A1 HK1216427 A1 HK 1216427A1 HK 16104446 A HK16104446 A HK 16104446A HK 1216427 A1 HK1216427 A1 HK 1216427A1
Authority
HK
Hong Kong
Prior art keywords
human antibody
antibody molecules
molecules
human
antibody
Prior art date
Application number
HK16104446.4A
Other languages
English (en)
Inventor
David Monk Phillip
Jermutus Lutz
Raymond Minter Ralph
Patricia Shorrock Celia
Original Assignee
Medimmune Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0407315.1A external-priority patent/GB0407315D0/en
Application filed by Medimmune Ltd filed Critical Medimmune Ltd
Publication of HK1216427A1 publication Critical patent/HK1216427A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK16104446.4A 2003-07-15 2016-04-19 針對 的人抗體分子 HK1216427A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48751203P 2003-07-15 2003-07-15
US55821604P 2004-03-31 2004-03-31
GBGB0407315.1A GB0407315D0 (en) 2003-07-15 2004-03-31 Human antibody molecules
US57379104P 2004-05-24 2004-05-24

Publications (1)

Publication Number Publication Date
HK1216427A1 true HK1216427A1 (zh) 2016-11-11

Family

ID=44535047

Family Applications (3)

Application Number Title Priority Date Filing Date
HK07101860.8A HK1097853A1 (zh) 2003-07-15 2007-02-15 針對 的人抗體分子
HK11109456.5A HK1155185A1 (zh) 2003-07-15 2011-09-07 用於 的人抗體分子
HK16104446.4A HK1216427A1 (zh) 2003-07-15 2016-04-19 針對 的人抗體分子

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HK07101860.8A HK1097853A1 (zh) 2003-07-15 2007-02-15 針對 的人抗體分子
HK11109456.5A HK1155185A1 (zh) 2003-07-15 2011-09-07 用於 的人抗體分子

Country Status (8)

Country Link
JP (3) JP5519567B2 (zh)
KR (1) KR101073590B1 (zh)
AU (1) AU2011200308B2 (zh)
CY (1) CY1111467T1 (zh)
HK (3) HK1097853A1 (zh)
MX (1) MXPA06000258A (zh)
NO (2) NO338853B1 (zh)
RU (1) RU2009148270A (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2016015785A (es) * 2014-06-18 2017-04-25 Medimmune Llc Metodos y medios de cultivo celular que comprenden n-acetilcisteina.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07508179A (ja) * 1992-08-21 1995-09-14 シェリング・コーポレーション ヒトインターロイキン−13
US20040023337A1 (en) * 2001-10-26 2004-02-05 Heavner George A. IL-13 mutein proteins, antibodies, compositions, methods and uses
EP1461428B1 (en) * 2001-12-03 2012-03-21 Alexion Pharmaceuticals, Inc. Method for producing hybrid antibodies
AU2003223497A1 (en) * 2002-04-05 2003-10-27 Centocor, Inc. Asthma-related anti-il-13 immunoglobulin derived proteins, compositions, methods and uses
JP2006503018A (ja) * 2002-08-30 2006-01-26 グラクソ グループ リミテッド ワクチン
GB0407315D0 (en) * 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
TWI307630B (en) * 2004-07-01 2009-03-21 Glaxo Group Ltd Immunoglobulins

Also Published As

Publication number Publication date
HK1155185A1 (zh) 2012-05-11
MXPA06000258A (es) 2006-07-03
NO342727B1 (no) 2018-07-30
KR101073590B1 (ko) 2011-10-14
JP2014101372A (ja) 2014-06-05
JP2011147454A (ja) 2011-08-04
JP5922686B2 (ja) 2016-05-24
RU2009148270A (ru) 2011-06-27
KR20060054312A (ko) 2006-05-22
HK1097853A1 (zh) 2007-07-06
JP5519567B2 (ja) 2014-06-11
JP2016047843A (ja) 2016-04-07
CY1111467T1 (el) 2015-08-05
NO20060730L (no) 2006-04-10
AU2011200308A1 (en) 2011-02-17
AU2011200308B2 (en) 2011-07-28
NO338853B1 (no) 2016-10-24
NO20160707A1 (no) 2016-04-27

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