RU2007147338A - Новые производные 2-азетидинона и их применение в качестве ингибиторов всасывания холестерина для лечения гиперлипидемии - Google Patents

Новые производные 2-азетидинона и их применение в качестве ингибиторов всасывания холестерина для лечения гиперлипидемии Download PDF

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Publication number
RU2007147338A
RU2007147338A RU2007147338/04A RU2007147338A RU2007147338A RU 2007147338 A RU2007147338 A RU 2007147338A RU 2007147338/04 A RU2007147338/04 A RU 2007147338/04A RU 2007147338 A RU2007147338 A RU 2007147338A RU 2007147338 A RU2007147338 A RU 2007147338A
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Russia
Prior art keywords
alkyl
formula
represents hydrogen
aryl
compound
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RU2007147338/04A
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English (en)
Russian (ru)
Inventor
Сусанне АЛЕНФАЛЬК (SE)
Сусанне Аленфальк
Микаэль ДАЛЬСТРЕМ (SE)
Микаэль Дальстрем
Фана ХУНЕГНАВ (SE)
Фана ХУНЕГНАВ
Стаффан КАРЛССОН (SE)
Стаффан Карлссон
Малин ЛЕМУРЕЛЛЬ (SE)
Малин Лемурелль
Анн-Маргрет ЛИНДКВИСТ (SE)
Анн-Маргрет Линдквист
Торе ШЕРЕТ (SE)
Торе Шерет
Ингемар СТАРКЕ (SE)
Ингемар Старке
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Астразенека Аб (Se)
Астразенека Аб
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Application filed by Астразенека Аб (Se), Астразенека Аб filed Critical Астразенека Аб (Se)
Publication of RU2007147338A publication Critical patent/RU2007147338A/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
RU2007147338/04A 2005-06-20 2006-06-19 Новые производные 2-азетидинона и их применение в качестве ингибиторов всасывания холестерина для лечения гиперлипидемии RU2007147338A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0501425 2005-06-20
SE0501425-3 2005-06-20

Publications (1)

Publication Number Publication Date
RU2007147338A true RU2007147338A (ru) 2009-07-27

Family

ID=37570721

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2007147338/04A RU2007147338A (ru) 2005-06-20 2006-06-19 Новые производные 2-азетидинона и их применение в качестве ингибиторов всасывания холестерина для лечения гиперлипидемии

Country Status (18)

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US (1) US7863265B2 (US20100216759A1-20100826-C00036.png)
EP (1) EP1896407A4 (US20100216759A1-20100826-C00036.png)
JP (1) JP2008546766A (US20100216759A1-20100826-C00036.png)
KR (1) KR20080019710A (US20100216759A1-20100826-C00036.png)
CN (1) CN101228123A (US20100216759A1-20100826-C00036.png)
AR (1) AR054484A1 (US20100216759A1-20100826-C00036.png)
AU (1) AU2006259949A1 (US20100216759A1-20100826-C00036.png)
BR (1) BRPI0612254A2 (US20100216759A1-20100826-C00036.png)
CA (1) CA2610890A1 (US20100216759A1-20100826-C00036.png)
EC (1) ECSP088114A (US20100216759A1-20100826-C00036.png)
IL (1) IL187736A0 (US20100216759A1-20100826-C00036.png)
MX (1) MX2007016483A (US20100216759A1-20100826-C00036.png)
NO (1) NO20076137L (US20100216759A1-20100826-C00036.png)
RU (1) RU2007147338A (US20100216759A1-20100826-C00036.png)
TW (1) TW200730493A (US20100216759A1-20100826-C00036.png)
UY (1) UY29607A1 (US20100216759A1-20100826-C00036.png)
WO (1) WO2006137782A1 (US20100216759A1-20100826-C00036.png)
ZA (1) ZA200710415B (US20100216759A1-20100826-C00036.png)

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Publication number Publication date
US20100216759A1 (en) 2010-08-26
EP1896407A4 (en) 2010-06-16
TW200730493A (en) 2007-08-16
US7863265B2 (en) 2011-01-04
AU2006259949A1 (en) 2006-12-28
WO2006137782A1 (en) 2006-12-28
UY29607A1 (es) 2007-01-31
EP1896407A1 (en) 2008-03-12
NO20076137L (no) 2008-01-18
ZA200710415B (en) 2008-10-29
MX2007016483A (es) 2008-03-10
CN101228123A (zh) 2008-07-23
KR20080019710A (ko) 2008-03-04
JP2008546766A (ja) 2008-12-25
AR054484A1 (es) 2007-06-27
BRPI0612254A2 (pt) 2016-09-06
IL187736A0 (en) 2008-08-07
ECSP088114A (es) 2008-02-20
CA2610890A1 (en) 2006-12-28

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