RU2007134565A - Антибактериальное вещество dm0507 и его применение - Google Patents
Антибактериальное вещество dm0507 и его применение Download PDFInfo
- Publication number
- RU2007134565A RU2007134565A RU2007134565/13A RU2007134565A RU2007134565A RU 2007134565 A RU2007134565 A RU 2007134565A RU 2007134565/13 A RU2007134565/13 A RU 2007134565/13A RU 2007134565 A RU2007134565 A RU 2007134565A RU 2007134565 A RU2007134565 A RU 2007134565A
- Authority
- RU
- Russia
- Prior art keywords
- jcm
- active substance
- bacillus subtilis
- antimicrobial active
- supernatant
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G11/00—Antibiotics
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Claims (6)
1. Противомикробное активное вещество DM0507, отличающееся тем, что его получают способом продуцирования, содержащим следующие этапы от (a) до (d):
(a) культивирование Bacillus subtilis;
(b) сбор супернатанта от полученной культуры;
(c) сбор осадка, образованного путем регулирования уровня pH супернатанта до 3 или ниже; и
(d) осуществление экстракции осадка этанолом.
2. Противомикробное активное вещество DM0507 по п.1, обладающее противомикробной активностью против следующих групп микроорганизмов от (A) до (D):
Группа (A) (аэробные/факультативные анаэробные микроорганизмы)
Streptococcus suis,
Streptococcus pneumoniae,
Streptococcus pyogenes,
Bacillus subtilis ATCC 6633,
Bacillus cereus var. mycoides ATCC 11778,
Arcanobacterium pyogenes,
Aeromonas salmonicida,
Aeromonas hydrophila,
Actinobacillus actinomycetemcomitans JCM 2434,
Actinobacillus pleuropneumoniae тип 2,
Haemophilus parasuis,
Pasteurella multocida тип D,
Pasteurella haemolytica,
Salmonella typhimurium,
Salmonella choleraesuis,
Klebsiella pneumoniae ATCC 10031,
Acinetobacter junii,
Acinetobacter sp.,
Stenotrophomonas maltophilia,
Legionella pneumophila серотип 1,
Mycoplasma gallisepticum и
Mycoplasma synoviae;
Группа (B) (микроаэрофильные микроорганизмы)
Campylobacter jejuni,
Campylobacter coli и
Helicobacter pylori ATCC 43526;
Группа (C) (облигатные анаэробные микроорганизмы),
Clostridium perfringens,
Clostridium difficile,
Propionibacterium acnes JCM 6425,
Bacteroides fragilis,
Porphyromonas gingivalis JCM 8525,
Tannerella forsythensis JCM 10827,
Lactobacillus acidophilus JCM 1132,
Bifidobacterium bifidum JCM 1255,
Anaerococcus prevotii JCM 6508 и
Fusobacterium nucleatum; и
Группа (D) (грибы)
Fusarium oxysporum.
3. Противомикробное активное вещество DM0507 по п.1 или 2, в котором Bacillus subtilis представляет собой Bacillus subtilis DB9011 (FERM BP-3418).
4. Противомикробный агент, содержащий противомикробное активное вещество DM0507 по любому из пп.1-3 в качестве активного компонента.
5. Пищевой продукт или напиток, содержащий противомикробное активное вещество DM0507 по любому из пп.1-3.
6. Способ продуцирования противомикробного активного вещества DM0507, отличающийся содержанием следующих этапов от (a) до (d):
(a) культивирование Bacillus subtilis;
(b) сбор супернатанта от полученной культуры;
(c) сбор осадка, образованного путем регулирования уровня pH супернатанта до 3 или ниже; и
(d) осуществление экстракции осадка этанолом.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2005/020318 WO2007052356A1 (ja) | 2005-11-04 | 2005-11-04 | 抗菌活性物質dm0507およびその利用 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2007134565A true RU2007134565A (ru) | 2009-03-27 |
RU2383622C2 RU2383622C2 (ru) | 2010-03-10 |
Family
ID=38005520
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2007134565/13A RU2383622C2 (ru) | 2005-11-04 | 2005-11-04 | Антибактериальное вещество dm0507 и его применение |
Country Status (7)
Country | Link |
---|---|
US (2) | US20080193577A1 (ru) |
EP (1) | EP1978099A4 (ru) |
JP (1) | JP3988953B2 (ru) |
CN (1) | CN101084318A (ru) |
RU (1) | RU2383622C2 (ru) |
TW (1) | TW200745339A (ru) |
WO (1) | WO2007052356A1 (ru) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8338162B2 (en) * | 2009-04-17 | 2012-12-25 | Anaeropharma Science, Inc. | Obligately anaerobic mutant lactic acid bacterium and preparation method therefor, and expression vector functioning in obligately anaerobic lactic acid bacterium |
JP5654279B2 (ja) * | 2010-07-21 | 2015-01-14 | 武 飯塚 | 医薬組成物およびその用途 |
CN102464438B (zh) * | 2010-11-18 | 2013-07-31 | 中国石油天然气股份有限公司 | 一种利用微生物降解井场含油污泥的方法 |
CN103333828B (zh) * | 2013-06-27 | 2014-08-27 | 中国农业大学 | 一种抗霉菌芽孢杆菌菌株及其抗菌产物在玉米储藏中的应用 |
WO2015088237A1 (ko) * | 2013-12-10 | 2015-06-18 | 현대자동차 주식회사 | 항균제 스크리닝 방법 |
EP3180420B1 (en) * | 2014-08-16 | 2020-10-21 | DCM Shriram Ltd. | Bacterium of bacillus subtilis ssp. shriramensis and uses thereof |
WO2017093977A1 (en) * | 2015-12-04 | 2017-06-08 | Universidad Eafit | A process for the induction of antimicrobial activity in aerobic endospore forming bacteria |
CN107683090A (zh) * | 2016-03-04 | 2018-02-09 | 有机科技农业株式会社 | 利用抗菌剂、农药、微生物的植物病害的防除方法、及新型枯草芽孢杆菌 |
KR101864409B1 (ko) * | 2017-12-19 | 2018-06-04 | 이엠생활환경 주식회사 | 한방 추출물 및 미생물 발효추출물을 유효성분으로 함유하는 항균, 살균 또는 항진균용 조성물 |
CN109010166B (zh) * | 2018-07-05 | 2022-01-28 | 上海普缇康生物技术有限公司 | 一种植物源小分子口腔清洁剂及其制备方法 |
CN109907072B (zh) * | 2019-03-31 | 2021-02-26 | 浙江大学 | 载菌纳米壳聚糖畜舍消毒剂及其制备方法和应用 |
CN110982734B (zh) * | 2019-11-21 | 2022-01-14 | 枣庄市杰诺生物酶有限公司 | 一株海洋来源的枯草芽孢杆菌2713、抗菌物质及其制备方法和应用 |
CN112592851B (zh) * | 2020-12-16 | 2022-12-02 | 广东省微生物研究所(广东省微生物分析检测中心) | 一株对水产病原菌有广谱拮抗作用的嗜酸乳杆菌及其应用 |
CN117088733B (zh) * | 2023-10-20 | 2023-12-29 | 四川嘉智生态科技有限公司 | 一种用于防治番茄土传病的生物有机肥及其制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS579792B2 (ru) * | 1974-06-19 | 1982-02-23 | ||
JPS6027391A (ja) * | 1983-07-27 | 1985-02-12 | Kitasato Inst:The | 抗生物質オ−ランチニン・bおよびその製造法 |
ATE166105T1 (de) * | 1991-07-01 | 1998-05-15 | Ahc Inc | Bacillus bakterium und dessen verwendung |
US5589381A (en) * | 1994-06-30 | 1996-12-31 | Rutgers, The State University Of New Jersey | Bacillus licheniformis producing antifungal agents and uses thereof for control of phytopathogenic fungi |
JPH11285378A (ja) * | 1997-12-01 | 1999-10-19 | Eisai Co Ltd | 抗菌作用を有する新規枯草菌 |
JPH11290063A (ja) * | 1998-04-14 | 1999-10-26 | Yushiro Chem Ind Co Ltd | 抗真菌・抗菌性培養組成物及び微生物 |
US6677141B2 (en) * | 1998-05-17 | 2004-01-13 | Honda Trading Corporation | Edible compositions of Bacillus subtilis natto cells containing water-soluble vitamin K |
US7247299B2 (en) * | 2002-11-27 | 2007-07-24 | Kemin Industries, Inc. | Antimicrobial compounds from Bacillus subtilis for use against animal and human pathogens |
-
2005
- 2005-11-04 CN CNA2005800198609A patent/CN101084318A/zh active Pending
- 2005-11-04 WO PCT/JP2005/020318 patent/WO2007052356A1/ja active Application Filing
- 2005-11-04 JP JP2006545833A patent/JP3988953B2/ja not_active Expired - Fee Related
- 2005-11-04 EP EP05805421A patent/EP1978099A4/en not_active Withdrawn
- 2005-11-04 US US11/911,690 patent/US20080193577A1/en not_active Abandoned
- 2005-11-04 RU RU2007134565/13A patent/RU2383622C2/ru not_active IP Right Cessation
-
2006
- 2006-11-03 TW TW095140813A patent/TW200745339A/zh unknown
-
2010
- 2010-05-19 US US12/782,928 patent/US20110171334A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1978099A1 (en) | 2008-10-08 |
EP1978099A4 (en) | 2011-08-24 |
RU2383622C2 (ru) | 2010-03-10 |
CN101084318A (zh) | 2007-12-05 |
JP3988953B2 (ja) | 2007-10-10 |
TW200745339A (en) | 2007-12-16 |
US20080193577A1 (en) | 2008-08-14 |
US20110171334A1 (en) | 2011-07-14 |
WO2007052356A1 (ja) | 2007-05-10 |
JPWO2007052356A1 (ja) | 2009-04-30 |
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Date | Code | Title | Description |
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MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20101105 |