RU2006105212A - Фармацевтические составы - Google Patents
Фармацевтические составы Download PDFInfo
- Publication number
- RU2006105212A RU2006105212A RU2006105212/15A RU2006105212A RU2006105212A RU 2006105212 A RU2006105212 A RU 2006105212A RU 2006105212/15 A RU2006105212/15 A RU 2006105212/15A RU 2006105212 A RU2006105212 A RU 2006105212A RU 2006105212 A RU2006105212 A RU 2006105212A
- Authority
- RU
- Russia
- Prior art keywords
- composition according
- klucel
- present
- amount
- polymers
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims 4
- 239000000203 mixture Substances 0.000 claims 39
- 229920000642 polymer Polymers 0.000 claims 19
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 13
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 13
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 13
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical group CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims 12
- 239000002775 capsule Substances 0.000 claims 8
- 239000002552 dosage form Substances 0.000 claims 8
- 238000004090 dissolution Methods 0.000 claims 7
- 239000003607 modifier Substances 0.000 claims 7
- 229920003134 Eudragit® polymer Polymers 0.000 claims 6
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 6
- 239000000314 lubricant Substances 0.000 claims 6
- 239000011159 matrix material Substances 0.000 claims 6
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 claims 6
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 6
- 239000007787 solid Substances 0.000 claims 6
- 239000004094 surface-active agent Substances 0.000 claims 6
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 5
- 229920001400 block copolymer Polymers 0.000 claims 5
- 229920003109 sodium starch glycolate Polymers 0.000 claims 5
- 239000008109 sodium starch glycolate Substances 0.000 claims 5
- 229940079832 sodium starch glycolate Drugs 0.000 claims 5
- -1 sucrose fatty acid ester Chemical class 0.000 claims 5
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 4
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 4
- 239000008186 active pharmaceutical agent Substances 0.000 claims 4
- 229920001531 copovidone Polymers 0.000 claims 4
- 229940088679 drug related substance Drugs 0.000 claims 4
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 3
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims 3
- 239000008101 lactose Substances 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- QZCLKYGREBVARF-UHFFFAOYSA-N Acetyl tributyl citrate Chemical compound CCCCOC(=O)CC(C(=O)OCCCC)(OC(C)=O)CC(=O)OCCCC QZCLKYGREBVARF-UHFFFAOYSA-N 0.000 claims 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 2
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 2
- 239000001856 Ethyl cellulose Substances 0.000 claims 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 2
- 229930195725 Mannitol Natural products 0.000 claims 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- ZFOZVQLOBQUTQQ-UHFFFAOYSA-N Tributyl citrate Chemical compound CCCCOC(=O)CC(O)(C(=O)OCCCC)CC(=O)OCCCC ZFOZVQLOBQUTQQ-UHFFFAOYSA-N 0.000 claims 2
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical group CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 claims 2
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims 2
- 238000010521 absorption reaction Methods 0.000 claims 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 2
- 229920002678 cellulose Polymers 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 229960001681 croscarmellose sodium Drugs 0.000 claims 2
- 229960000913 crospovidone Drugs 0.000 claims 2
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 2
- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 235000019325 ethyl cellulose Nutrition 0.000 claims 2
- 229920001249 ethyl cellulose Polymers 0.000 claims 2
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 2
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 claims 2
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 claims 2
- 238000001746 injection moulding Methods 0.000 claims 2
- 229960001375 lactose Drugs 0.000 claims 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- 239000000594 mannitol Substances 0.000 claims 2
- 235000010355 mannitol Nutrition 0.000 claims 2
- 229960001855 mannitol Drugs 0.000 claims 2
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims 2
- 239000004014 plasticizer Substances 0.000 claims 2
- 229920001451 polypropylene glycol Polymers 0.000 claims 2
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 claims 2
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 229960002668 sodium chloride Drugs 0.000 claims 2
- 239000008107 starch Substances 0.000 claims 2
- 229940032147 starch Drugs 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 239000000454 talc Substances 0.000 claims 2
- 229910052623 talc Inorganic materials 0.000 claims 2
- 235000012222 talc Nutrition 0.000 claims 2
- WEAPVABOECTMGR-UHFFFAOYSA-N triethyl 2-acetyloxypropane-1,2,3-tricarboxylate Chemical compound CCOC(=O)CC(C(=O)OCC)(OC(C)=O)CC(=O)OCC WEAPVABOECTMGR-UHFFFAOYSA-N 0.000 claims 2
- 239000001069 triethyl citrate Substances 0.000 claims 2
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 claims 2
- 235000013769 triethyl citrate Nutrition 0.000 claims 2
- 239000000811 xylitol Substances 0.000 claims 2
- 229960002675 xylitol Drugs 0.000 claims 2
- 235000010447 xylitol Nutrition 0.000 claims 2
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 2
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims 1
- DOUBAFNWVFAWEC-UHFFFAOYSA-N 3-hydroxypropyl acetate Chemical compound CC(=O)OCCCO DOUBAFNWVFAWEC-UHFFFAOYSA-N 0.000 claims 1
- 229920000623 Cellulose acetate phthalate Polymers 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- 229920003114 HPC-L Polymers 0.000 claims 1
- 102000004856 Lectins Human genes 0.000 claims 1
- 108090001090 Lectins Proteins 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- AOBORMOPSGHCAX-UHFFFAOYSA-N Tocophersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-UHFFFAOYSA-N 0.000 claims 1
- 229920002301 cellulose acetate Polymers 0.000 claims 1
- 229940081734 cellulose acetate phthalate Drugs 0.000 claims 1
- 229940075614 colloidal silicon dioxide Drugs 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 125000004177 diethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 235000010445 lecithin Nutrition 0.000 claims 1
- 239000000787 lecithin Substances 0.000 claims 1
- 229940067606 lecithin Drugs 0.000 claims 1
- 239000002523 lectin Substances 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 239000012907 medicinal substance Substances 0.000 claims 1
- 229920003117 medium viscosity grade hydroxypropyl cellulose Polymers 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 238000005192 partition Methods 0.000 claims 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 claims 1
- 235000012239 silicon dioxide Nutrition 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48915903P | 2003-07-21 | 2003-07-21 | |
| US60/489,159 | 2003-07-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2006105212A true RU2006105212A (ru) | 2006-06-10 |
Family
ID=34102831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006105212/15A RU2006105212A (ru) | 2003-07-21 | 2004-07-21 | Фармацевтические составы |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8673350B2 (enExample) |
| EP (1) | EP1646355A4 (enExample) |
| JP (2) | JP5072358B2 (enExample) |
| KR (1) | KR20060052847A (enExample) |
| CN (1) | CN1826101A (enExample) |
| AR (1) | AR046399A1 (enExample) |
| AU (1) | AU2004258981A1 (enExample) |
| BR (1) | BRPI0412678A (enExample) |
| CA (1) | CA2533151A1 (enExample) |
| IL (1) | IL172824A0 (enExample) |
| IS (1) | IS8309A (enExample) |
| MA (1) | MA27927A1 (enExample) |
| MX (1) | MXPA06000791A (enExample) |
| NO (1) | NO20060852L (enExample) |
| RU (1) | RU2006105212A (enExample) |
| TW (1) | TW200526274A (enExample) |
| WO (1) | WO2005009380A2 (enExample) |
| ZA (1) | ZA200510379B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1047537A1 (zh) * | 1999-07-30 | 2003-02-28 | Smithkline Beecham Plc | 多元藥物劑型 |
| US7842308B2 (en) * | 2001-01-30 | 2010-11-30 | Smithkline Beecham Limited | Pharmaceutical formulation |
| US7883721B2 (en) | 2001-01-30 | 2011-02-08 | Smithkline Beecham Limited | Pharmaceutical formulation |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| PE20060003A1 (es) | 2004-03-12 | 2006-03-01 | Smithkline Beecham Plc | Formulacion farmaceutica polimerica para moldear por inyeccion |
| WO2009050193A1 (en) * | 2007-10-15 | 2009-04-23 | Glaxo Group Limited | Method and apparatus for manufacturing filled linkers |
| EP2537506A1 (en) | 2007-10-15 | 2012-12-26 | Capsugel Belgium NV | Linkers for multipart dosage forms for release of one or more parmaceutical compositions, and the resulting dosage forms |
| CN101827586A (zh) * | 2007-10-15 | 2010-09-08 | 葛兰素集团有限公司 | 用于阶段性释放一种或多种物质的多部分胶囊 |
| CN101827572A (zh) * | 2007-10-15 | 2010-09-08 | 葛兰素集团有限公司 | 用于释放药物组合物的有板条的胶囊壳 |
| EP2219624A2 (en) * | 2007-11-08 | 2010-08-25 | Glaxo Group Limited | Pharmaceutical formulations |
| MX2010013731A (es) * | 2008-06-13 | 2011-01-14 | Glaxo Group Ltd | Cubierta de capsula de hidroxipropil celulosa. |
| JP6267125B2 (ja) * | 2011-10-12 | 2018-01-24 | ダウ グローバル テクノロジーズ エルエルシー | 射出成型された剤形 |
| TWI535784B (zh) | 2014-08-26 | 2016-06-01 | 財團法人工業技術研究院 | 剪切增稠配方、及包含其之複合材料 |
| GB201519128D0 (en) | 2015-10-29 | 2015-12-16 | Univ Central Lancashire | Solid forms and methods of preparing the same |
| WO2018008660A1 (ja) | 2016-07-06 | 2018-01-11 | クオリカプス株式会社 | 硬度が改善された硬質カプセル、及びその製造方法 |
| CN108782546A (zh) * | 2017-04-28 | 2018-11-13 | 江苏邦盛生物科技有限责任公司 | 一种桶混农药增效助剂及其制备方法 |
| WO2019013260A1 (ja) * | 2017-07-11 | 2019-01-17 | クオリカプス株式会社 | 腸溶性硬質カプセル |
| JP7233852B2 (ja) * | 2018-04-17 | 2023-03-07 | キョーリンリメディオ株式会社 | 変色が抑制された固形製剤 |
| EP3811976B1 (en) | 2018-06-22 | 2024-02-21 | Qualicaps Co., Ltd. | Enteric hard capsule |
| WO2020212829A1 (en) * | 2019-04-17 | 2020-10-22 | Amruth Gowda Doddaveerappa | Multi-component pharmaceutical single dosage forms and methods employed thereof |
Family Cites Families (148)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3186910A (en) | 1962-03-08 | 1965-06-01 | Jacob A Glassman | Method for producing peroral capsules |
| US3228789A (en) | 1962-10-22 | 1966-01-11 | Jacob A Glassman | Peroral capsules and tablets and the method for making same |
| US3314809A (en) | 1963-02-08 | 1967-04-18 | Hercules Inc | Process of making thermoplastic shaped articles from hydroxypropyl cellulose having an m.s. of at least 2 |
| US3394983A (en) | 1963-06-14 | 1968-07-30 | American Cyanamid Co | Dip-dyeing capsules |
| FR1454013A (fr) | 1965-08-18 | 1966-07-22 | Pluripharm | Mode de présentation de deux médicaments associés |
| US3399803A (en) | 1966-10-11 | 1968-09-03 | Parke Davis & Co | Self-locking medicament capsule |
| US3779942A (en) | 1970-12-04 | 1973-12-18 | Minnesota Mining & Mfg | Capsules and process for forming capsules |
| US3723312A (en) | 1970-12-18 | 1973-03-27 | Ppg Industries Inc | Combined stain retardant and separator interleaving material for glass sheets |
| DE2428397C3 (de) | 1974-06-12 | 1978-05-18 | Scherer Hartkapsel Gmbh, 6930 Eberbach | Zweiteilige Kapsel aus Hartgelatine |
| NL7610038A (en) | 1976-09-09 | 1978-03-13 | Tapanahony N V | Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively |
| DE2722822C2 (de) | 1977-05-20 | 1984-11-08 | Capsugel AG, Basel | Verfahren zum Herstellen einer zum Aufnehmen eines viskosen Stoffes, insbesondere eines flüssigen Arzneimittels, geeigneten Steckkapsel |
| US4250097A (en) | 1978-03-08 | 1981-02-10 | Syntex (U.S.A.) Inc. | Compositions for and a method of preventing diabetic complications |
| US4281763A (en) | 1979-10-31 | 1981-08-04 | Pace Joseph A | Two-piece hardshell, soluble and digestible liquid containing gelatin capsule |
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| US4766728A (en) | 1983-03-28 | 1988-08-30 | Rexa Corporation | Flow matching valve and hydraulic system employing same |
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| EP0091908A1 (en) | 1981-10-21 | 1983-10-26 | SMITH, Charles E | A method and composition for substrate coating |
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| GR78492B (enExample) | 1982-03-26 | 1984-09-27 | Warner Lambert Co | |
| FR2524311A1 (fr) | 1982-04-05 | 1983-10-07 | Azalbert Gilles | Gelule compartimentee aux fins d'ingestions simultanees a effets differes |
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| USD285837S (en) | 1982-12-20 | 1986-09-23 | Warner-Lambert Company | Pharmaceutical capsule |
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-
2004
- 2004-07-19 TW TW093121491A patent/TW200526274A/zh unknown
- 2004-07-21 CN CNA2004800211420A patent/CN1826101A/zh active Pending
- 2004-07-21 RU RU2006105212/15A patent/RU2006105212A/ru not_active Application Discontinuation
- 2004-07-21 CA CA002533151A patent/CA2533151A1/en not_active Abandoned
- 2004-07-21 BR BRPI0412678-5A patent/BRPI0412678A/pt not_active Application Discontinuation
- 2004-07-21 KR KR1020067001339A patent/KR20060052847A/ko not_active Withdrawn
- 2004-07-21 MX MXPA06000791A patent/MXPA06000791A/es unknown
- 2004-07-21 AR ARP040102582A patent/AR046399A1/es unknown
- 2004-07-21 WO PCT/US2004/023542 patent/WO2005009380A2/en not_active Ceased
- 2004-07-21 AU AU2004258981A patent/AU2004258981A1/en not_active Abandoned
- 2004-07-21 EP EP04778865A patent/EP1646355A4/en not_active Withdrawn
- 2004-07-21 US US10/565,462 patent/US8673350B2/en not_active Expired - Fee Related
- 2004-07-21 JP JP2006521230A patent/JP5072358B2/ja not_active Expired - Fee Related
-
2005
- 2005-12-21 ZA ZA200510379A patent/ZA200510379B/en unknown
- 2005-12-26 IL IL172824A patent/IL172824A0/en unknown
-
2006
- 2006-01-18 MA MA28739A patent/MA27927A1/fr unknown
- 2006-02-17 IS IS8309A patent/IS8309A/is unknown
- 2006-02-21 NO NO20060852A patent/NO20060852L/no not_active Application Discontinuation
-
2012
- 2012-01-27 JP JP2012015580A patent/JP2012140433A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP5072358B2 (ja) | 2012-11-14 |
| CN1826101A (zh) | 2006-08-30 |
| BRPI0412678A (pt) | 2006-10-03 |
| AU2004258981A1 (en) | 2005-02-03 |
| TW200526274A (en) | 2005-08-16 |
| CA2533151A1 (en) | 2005-02-03 |
| JP2012140433A (ja) | 2012-07-26 |
| NO20060852L (no) | 2006-04-20 |
| MA27927A1 (fr) | 2006-06-01 |
| WO2005009380A2 (en) | 2005-02-03 |
| KR20060052847A (ko) | 2006-05-19 |
| US8673350B2 (en) | 2014-03-18 |
| WO2005009380A3 (en) | 2005-06-02 |
| IS8309A (is) | 2006-02-17 |
| JP2006528197A (ja) | 2006-12-14 |
| EP1646355A2 (en) | 2006-04-19 |
| ZA200510379B (en) | 2006-12-27 |
| EP1646355A4 (en) | 2012-04-18 |
| US20060177496A1 (en) | 2006-08-10 |
| MXPA06000791A (es) | 2006-04-07 |
| IL172824A0 (en) | 2006-06-11 |
| AR046399A1 (es) | 2005-12-07 |
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| FA94 | Acknowledgement of application withdrawn (non-payment of fees) |
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