RU2005140573A - Составы для лечения артритных состояний - Google Patents
Составы для лечения артритных состояний Download PDFInfo
- Publication number
- RU2005140573A RU2005140573A RU2005140573/15A RU2005140573A RU2005140573A RU 2005140573 A RU2005140573 A RU 2005140573A RU 2005140573/15 A RU2005140573/15 A RU 2005140573/15A RU 2005140573 A RU2005140573 A RU 2005140573A RU 2005140573 A RU2005140573 A RU 2005140573A
- Authority
- RU
- Russia
- Prior art keywords
- extract
- acid
- procyanidins
- glucosamine
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract 8
- 230000002917 arthritic effect Effects 0.000 title claims 2
- CWEZAWNPTYBADX-UHFFFAOYSA-N Procyanidin Natural products OC1C(OC2C(O)C(Oc3c2c(O)cc(O)c3C4C(O)C(Oc5cc(O)cc(O)c45)c6ccc(O)c(O)c6)c7ccc(O)c(O)c7)c8c(O)cc(O)cc8OC1c9ccc(O)c(O)c9 CWEZAWNPTYBADX-UHFFFAOYSA-N 0.000 claims abstract 6
- 229920002414 procyanidin Polymers 0.000 claims abstract 6
- NBGQZFQREPIKMG-UHFFFAOYSA-N 3beta-hydroxy-beta-boswellic acid Natural products C1CC(O)C(C)(C(O)=O)C2CCC3(C)C4(C)CCC5(C)CCC(C)C(C)C5C4=CCC3C21C NBGQZFQREPIKMG-UHFFFAOYSA-N 0.000 claims abstract 4
- NBGQZFQREPIKMG-PONOSELZSA-N Boswellic acid Chemical compound C1C[C@@H](O)[C@](C)(C(O)=O)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C NBGQZFQREPIKMG-PONOSELZSA-N 0.000 claims abstract 4
- 239000002253 acid Substances 0.000 claims abstract 3
- 229960002442 glucosamine Drugs 0.000 claims abstract 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims abstract 2
- 239000000284 extract Substances 0.000 claims 12
- 240000007551 Boswellia serrata Species 0.000 claims 5
- 235000012035 Boswellia serrata Nutrition 0.000 claims 5
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 claims 5
- UYUXSRADSPPKRZ-UHFFFAOYSA-N D-glucuronic acid gamma-lactone Natural products O=CC(O)C1OC(=O)C(O)C1O UYUXSRADSPPKRZ-UHFFFAOYSA-N 0.000 claims 5
- UYUXSRADSPPKRZ-SKNVOMKLSA-N D-glucurono-6,3-lactone Chemical compound O=C[C@H](O)[C@H]1OC(=O)[C@@H](O)[C@H]1O UYUXSRADSPPKRZ-SKNVOMKLSA-N 0.000 claims 5
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 claims 5
- 241001299682 Salix purpurea Species 0.000 claims 5
- 229950002441 glucurolactone Drugs 0.000 claims 5
- 229940097043 glucuronic acid Drugs 0.000 claims 5
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 claims 4
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 claims 4
- MBLBDJOUHNCFQT-LXGUWJNJSA-N N-acetylglucosamine Natural products CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 claims 4
- 229950006780 n-acetylglucosamine Drugs 0.000 claims 4
- 240000006365 Vitis vinifera Species 0.000 claims 3
- 235000014787 Vitis vinifera Nutrition 0.000 claims 3
- 235000002532 grape seed extract Nutrition 0.000 claims 3
- CQRYARSYNCAZFO-UHFFFAOYSA-N salicyl alcohol Chemical compound OCC1=CC=CC=C1O CQRYARSYNCAZFO-UHFFFAOYSA-N 0.000 claims 3
- 244000052707 Camellia sinensis Species 0.000 claims 2
- 235000006468 Thea sinensis Nutrition 0.000 claims 2
- 150000003904 phospholipids Chemical class 0.000 claims 2
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 claims 1
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 235000007882 dietary composition Nutrition 0.000 claims 1
- 239000002417 nutraceutical Substances 0.000 claims 1
- 235000021436 nutraceutical agent Nutrition 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/76—Salicaceae (Willow family), e.g. poplar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Road Signs Or Road Markings (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Saccharide Compounds (AREA)
Claims (6)
1. Составы, содержащие чистый салигенин или его производные или содержащие их экстракты, выбранные из обогащенного салигенином экстракта Salix rubra, по существу чистую босвеловую кислоту или ее полусинтетическое производное или обогащенный босвеловой кислотой экстракт Boswellia serrata, процианидины из Vitis vinifera или из Camellia sinensis или реин или их липофильные производные, N-ацетил-глюкозамин, глюкуроновую кислоту или глюкуронолактон.
2. Составы по п.1, содержащие экстракт Salix rubra, содержащий 25% салигенина по весу, экстракт Boswellia serrata, содержащий 20% босвеловой кислоты по весу, процианидины из Vitis vinifera или из Camellia sinensis, необязательно, в комплексе с фосфолипидами или реином или их липофильные производные, N-ацетил-глюкозамин, глюкуроновую кислоту или глюкуронолактон.
3. Составы по п.1, в которых экстракт Salix rubra, экстракт Boswellia serrata, процианидины, N-ацетил-глюкозамин, глюкуроновая кислота или глюкуронолактон присутствуют в составах в весовых соотношениях 2:1:1:1:1 соответственно.
4. Составы по п.2, содержащие 100-500 мг 25% экстракта Salix rubra, 50-150 мг процианидинов, необязательно, в форме комплексов с фосфолипидами, 20-200 мг экстракта Boswellia serrata и по 10-500 мг глюкозамина и глюкуроновой кислоты или глюкуронолактона.
5. Составы по любому из пп.1-3 в форме капсул, содержащих в качестве носителя масло Enothera biennis.
6. Применение комбинации чистого салигенина или его производных или содержащих их экстрактов, выбранных из обогащенного салигенином экстракта Salix rubra, по существу чистой босвеловой кислоты или ее полусинтетического производного или обогащенного босвеловой кислотой экстракта Boswellia serrata, процианидинов из Vitis vinifera или из Camellia sinensis или реина или их липофильных производных, N-ацетил-глюкозамина, глюкуроновой кислоты или глюкуронолактона, для приготовления фармацевтических, нутрицевтических или диетических композиций для лечения ревматоидного артрита и артритных состояний.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001311A ITMI20031311A1 (it) | 2003-06-27 | 2003-06-27 | Formulazioni per il trattamento di disturbi artrosici. |
| ITMI2003A001311 | 2003-06-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2005140573A true RU2005140573A (ru) | 2006-06-10 |
| RU2349336C2 RU2349336C2 (ru) | 2009-03-20 |
Family
ID=30131307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2005140573/15A RU2349336C2 (ru) | 2003-06-27 | 2004-06-01 | Составы для лечения артритных состояний |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8343554B2 (ru) |
| EP (1) | EP1648484B1 (ru) |
| JP (1) | JP2007513051A (ru) |
| KR (2) | KR101119418B1 (ru) |
| CN (1) | CN1812802A (ru) |
| AT (1) | ATE414526T1 (ru) |
| AU (1) | AU2004253242B2 (ru) |
| BR (1) | BRPI0411895B1 (ru) |
| CA (1) | CA2530494C (ru) |
| DE (1) | DE602004017871D1 (ru) |
| DK (1) | DK1648484T3 (ru) |
| ES (1) | ES2315662T3 (ru) |
| IL (1) | IL172773A (ru) |
| IT (1) | ITMI20031311A1 (ru) |
| NO (1) | NO333877B1 (ru) |
| NZ (1) | NZ544400A (ru) |
| PL (1) | PL1648484T3 (ru) |
| PT (1) | PT1648484E (ru) |
| RU (1) | RU2349336C2 (ru) |
| SI (1) | SI1648484T1 (ru) |
| WO (1) | WO2005002611A1 (ru) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20040439A1 (it) * | 2004-09-16 | 2004-12-16 | Ca Di Group S R L | Prodotto con azione antinfiammatoria selettiva e azione contro la fibrogenesi tissutale. |
| ITMI20051349A1 (it) * | 2005-07-14 | 2007-01-15 | Indena Spa | Estratto di salice uso e formulazioni che lo contengono |
| CN100417415C (zh) * | 2006-06-28 | 2008-09-10 | 文彦春 | 浸润治疗关节炎的药物 |
| EP1886712A1 (en) * | 2006-08-08 | 2008-02-13 | Indena S.P.A. | Compositions for the treatment of chronic degenerative inflammatory conditions |
| FR2907339B1 (fr) * | 2006-10-20 | 2009-04-24 | Inneov Lab | Composition comprenant de la glucosamine et au moins un polyphenol. |
| CN101371823B (zh) * | 2007-03-19 | 2010-09-15 | 上海慈瑞医药科技有限公司 | 二乙酰大黄酸缓释胶囊的制备工艺 |
| FR2918376B1 (fr) | 2007-07-04 | 2011-10-28 | Mathieu Borge | Compositions liquides ou pateuses destinees a l'apport en elements essentiels a la synthese et a la constitution des proteoglycanes, notamment pour le traitement de la degradation du cartilage |
| WO2009031826A1 (en) * | 2007-09-04 | 2009-03-12 | Catholic University Industry Academic Cooperation Foundation | Process for preparing vitis vinifera pip extract and pharmaceutical composition for preventing or treating rheumatoid arthritis comprising the same |
| KR101682512B1 (ko) | 2008-09-15 | 2016-12-05 | 라일라 뉴트라슈티칼스 | 보스웰리아 세라타 추출물을 포함하는 상승적인 항-염증 조성물 |
| KR101096574B1 (ko) * | 2008-12-12 | 2011-12-20 | 에이치 엘 지노믹스(주) | 유럽종 포도의 씨 추출물을 함유하는 골다공증 예방 또는 치료용 약학 조성물 |
| KR101099021B1 (ko) * | 2009-04-24 | 2011-12-28 | 에이치 엘 지노믹스(주) | 유럽종 포도의 씨 추출물을 함유하는 골관절염 예방 또는 치료용 약학 조성물 |
| JP5734578B2 (ja) * | 2009-09-03 | 2015-06-17 | ナガセケムテックス株式会社 | ヒアルロン酸増量剤 |
| WO2011079203A1 (en) * | 2009-12-23 | 2011-06-30 | Bae Systems Aerospace & Defense Group Inc. | Quick release buckle with dual release |
| RU2578025C2 (ru) | 2010-02-15 | 2016-03-20 | Лайла Ньютрасьютикалз | Новый низкополярный экстракт камеде-смолы boswellia и его синергетические композиции |
| US8828377B2 (en) | 2010-03-15 | 2014-09-09 | Laila Nutraceuticals | Boswellia oil, its fractions and compositions for enhancing brain function |
| US11123364B2 (en) | 2011-06-21 | 2021-09-21 | Bvw Holding Ag | Medical device comprising boswellic acid |
| RU2476213C1 (ru) * | 2012-02-15 | 2013-02-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежская государственная медицинская академия имени Н.Н. Бурденко Министерства здравоохранения и социального развития" (ГБОУ ВПО ВГМА им. Н.Н. Бурденко Минздравсоцразвития России) | Способ комплексного лечения вторичного остеоартроза при ревматоидном артрите |
| JP6270362B2 (ja) * | 2013-07-17 | 2018-01-31 | 日本水産株式会社 | 関節痛改善剤 |
| JP6153436B2 (ja) * | 2013-09-27 | 2017-06-28 | 小林製薬株式会社 | 経口組成物 |
| US9975917B1 (en) | 2017-09-20 | 2018-05-22 | King Saud University | Pentacyclic triterpenoidal derivatives |
| CN111110863A (zh) * | 2020-01-21 | 2020-05-08 | 郑州大学 | 大黄酸磷脂复合物及其制备方法和应用、大黄酸磷脂复合物长循环脂质体及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3970M (ru) | 1963-11-26 | 1966-02-28 | ||
| GB1155973A (en) * | 1965-06-26 | 1969-06-25 | Ajinomoto Kk | Spiroacetal Diamine Derivatives and their use as Curing Agents for Epoxy Resins |
| DE3347522A1 (de) * | 1983-12-30 | 1985-07-11 | Troponwerke GmbH & Co KG, 5000 Köln | N-glycosylierte carbonsaeureamid-derivate als mittel bei der bekaempfung von erkrankungen des rheumatischen formenkreises |
| DE3602670A1 (de) | 1986-01-29 | 1987-07-30 | Speck Ulrich | Verwendung von n-acetylglucosamin zur therapie degenerativer gelenkprozesse und verwandter erkrankungen |
| US5629351A (en) | 1995-04-13 | 1997-05-13 | Council Of Scientific & Industrial Research | Boswellic acid compositions and preparation thereof |
| DE19531067A1 (de) | 1995-08-23 | 1997-02-27 | Hermann P T Prof Dr Med Ammon | Verwendung von Boswelliasäure und ihren Derivaten zur Hemmung der normalen und gesteigerten Leukozytenelastase- oder Plasminaktivität |
| US5762936A (en) * | 1996-09-04 | 1998-06-09 | Biotics Research Corporation | Antioxidant derived from lentil and its preparation and uses |
| JP4153057B2 (ja) | 1997-03-10 | 2008-09-17 | 中国化薬株式会社 | Ｄ−グルクロノラクトンの製造方法 |
| US6107334A (en) * | 1998-02-23 | 2000-08-22 | Wake Forest University | Dietary control of arachidonic acid metabolism |
| US6761903B2 (en) * | 1999-06-30 | 2004-07-13 | Lipocine, Inc. | Clear oil-containing pharmaceutical compositions containing a therapeutic agent |
| MXPA01011606A (es) * | 1999-05-14 | 2003-09-10 | Univ California | Terapia anti-inflamatoria para infeccion mediada por inflamacion. |
| JP2002153294A (ja) * | 2000-11-21 | 2002-05-28 | Hayashibara Biochem Lab Inc | グルクロン酸類及び／又はｄ−グルクロノラクトンの製造方法とその用途 |
| US6451045B1 (en) * | 2001-02-22 | 2002-09-17 | Alsius Corporation | Heat exchange catheter having a helically wrapped heat exchanger |
| US6541045B1 (en) * | 2002-01-04 | 2003-04-01 | Nutraceutical Corporation | Herbal composition and method for combating inflammation |
-
2003
- 2003-06-27 IT IT001311A patent/ITMI20031311A1/it unknown
-
2004
- 2004-01-06 US US10/562,205 patent/US8343554B2/en not_active Expired - Fee Related
- 2004-06-01 DK DK04735566T patent/DK1648484T3/da active
- 2004-06-01 JP JP2006515812A patent/JP2007513051A/ja active Pending
- 2004-06-01 KR KR1020057024594A patent/KR101119418B1/ko active IP Right Grant
- 2004-06-01 ES ES04735566T patent/ES2315662T3/es not_active Expired - Lifetime
- 2004-06-01 PT PT04735566T patent/PT1648484E/pt unknown
- 2004-06-01 CN CNA2004800177557A patent/CN1812802A/zh active Pending
- 2004-06-01 CA CA2530494A patent/CA2530494C/en not_active Expired - Fee Related
- 2004-06-01 EP EP04735566A patent/EP1648484B1/en not_active Expired - Lifetime
- 2004-06-01 SI SI200430968T patent/SI1648484T1/sl unknown
- 2004-06-01 AT AT04735566T patent/ATE414526T1/de active
- 2004-06-01 NZ NZ544400A patent/NZ544400A/en unknown
- 2004-06-01 RU RU2005140573/15A patent/RU2349336C2/ru not_active IP Right Cessation
- 2004-06-01 PL PL04735566T patent/PL1648484T3/pl unknown
- 2004-06-01 KR KR1020117007487A patent/KR20110039400A/ko not_active Application Discontinuation
- 2004-06-01 WO PCT/EP2004/005875 patent/WO2005002611A1/en active Application Filing
- 2004-06-01 DE DE602004017871T patent/DE602004017871D1/de not_active Expired - Lifetime
- 2004-06-01 BR BRPI0411895A patent/BRPI0411895B1/pt not_active IP Right Cessation
- 2004-06-01 AU AU2004253242A patent/AU2004253242B2/en not_active Ceased
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2005
- 2005-12-22 IL IL172773A patent/IL172773A/en active IP Right Grant
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Also Published As
| Publication number | Publication date |
|---|---|
| US20060280811A1 (en) | 2006-12-14 |
| PT1648484E (pt) | 2009-01-09 |
| IL172773A0 (en) | 2006-04-10 |
| ITMI20031311A1 (it) | 2004-12-28 |
| IL172773A (en) | 2010-12-30 |
| BRPI0411895A (pt) | 2006-08-29 |
| BRPI0411895B1 (pt) | 2015-11-10 |
| JP2007513051A (ja) | 2007-05-24 |
| ATE414526T1 (de) | 2008-12-15 |
| DK1648484T3 (da) | 2009-01-19 |
| DE602004017871D1 (de) | 2009-01-02 |
| KR101119418B1 (ko) | 2012-02-22 |
| KR20060032147A (ko) | 2006-04-14 |
| CN1812802A (zh) | 2006-08-02 |
| AU2004253242B2 (en) | 2010-02-18 |
| PL1648484T3 (pl) | 2009-04-30 |
| RU2349336C2 (ru) | 2009-03-20 |
| SI1648484T1 (sl) | 2009-02-28 |
| WO2005002611A1 (en) | 2005-01-13 |
| CA2530494C (en) | 2013-04-30 |
| US8343554B2 (en) | 2013-01-01 |
| AU2004253242A1 (en) | 2005-01-13 |
| ES2315662T3 (es) | 2009-04-01 |
| NZ544400A (en) | 2009-04-30 |
| CA2530494A1 (en) | 2005-01-13 |
| EP1648484B1 (en) | 2008-11-19 |
| KR20110039400A (ko) | 2011-04-15 |
| NO333877B1 (no) | 2013-10-07 |
| ITMI20031311A0 (it) | 2003-06-27 |
| NO20056161L (no) | 2005-12-23 |
| EP1648484A1 (en) | 2006-04-26 |
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