RU2005130641A - Диагностика аутизма - Google Patents
Диагностика аутизма Download PDFInfo
- Publication number
- RU2005130641A RU2005130641A RU2005130641/15A RU2005130641A RU2005130641A RU 2005130641 A RU2005130641 A RU 2005130641A RU 2005130641/15 A RU2005130641/15 A RU 2005130641/15A RU 2005130641 A RU2005130641 A RU 2005130641A RU 2005130641 A RU2005130641 A RU 2005130641A
- Authority
- RU
- Russia
- Prior art keywords
- seq
- autism
- determined
- yes
- sample
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Neurosurgery (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steering Control In Accordance With Driving Conditions (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Claims (6)
1. Способ диагностики аутизма у субъектов с подозрением на аутизм посредством проведения анализа пробы ткани, пробы жидкости организма и/или пробы плазмы крови на наличие высоких концентраций определенных пептидов, имеющих молекулярную массу соответственно 1779±1 Да, 1865±1 Да и 2022±1 Да, и имеющих аминокислотные последовательности:
SKITHRIHWESASLL (SEQ. ID. № 1),
SSKITHRIHWESASLL (SEQ. ID. № 2) и/или
SSKITHRIHWESASLLR (SEQ. ID. № 3).
2. Способ по п. 1, в котором количество пептида(ов) выше в 10 раз по сравнению с таковым в пробе, полученной от субъекта без аутизма.
3. Способ по пп. 1 и 2, в котором используется любой количественный иммунохимический анализ.
4. Способ по пп. 1 и 2, в котором соответствующий пептид определяют с использованием технологии ELISA.
5. Способ по пп. 1 и 2, в котором соответствующий пептид определяют с использованием технологии РИА.
6. Способ по пп. 1 и 2, в котором соответствующий пептид определяют с использованием системы SELDI-TOF-MS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0300586A SE0300586L (sv) | 2003-03-04 | 2003-03-04 | Diagnos av autism |
| SE0300586-5 | 2003-03-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2005130641A true RU2005130641A (ru) | 2006-02-10 |
| RU2340900C2 RU2340900C2 (ru) | 2008-12-10 |
Family
ID=20290572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2005130641/15A RU2340900C2 (ru) | 2003-03-04 | 2004-03-02 | Диагностика аутизма |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8268576B2 (ru) |
| EP (1) | EP1608982B9 (ru) |
| JP (1) | JP4452715B2 (ru) |
| KR (1) | KR101096487B1 (ru) |
| CN (1) | CN1795386B (ru) |
| AT (1) | ATE371192T1 (ru) |
| AU (1) | AU2004217571B2 (ru) |
| BR (1) | BRPI0408067A (ru) |
| CA (1) | CA2518066C (ru) |
| DE (1) | DE602004008439T2 (ru) |
| DK (1) | DK1608982T3 (ru) |
| ES (1) | ES2293234T3 (ru) |
| NZ (1) | NZ542149A (ru) |
| PL (1) | PL1608982T3 (ru) |
| PT (1) | PT1608982E (ru) |
| RU (1) | RU2340900C2 (ru) |
| SE (1) | SE0300586L (ru) |
| WO (1) | WO2004079371A1 (ru) |
| ZA (1) | ZA200507082B (ru) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4677556B2 (ja) * | 2005-04-22 | 2011-04-27 | 国立大学法人 千葉大学 | 自閉症の診断薬 |
| SG182971A1 (en) * | 2007-07-26 | 2012-08-30 | Phenomenome Discoveries Inc | Methods for the diagnosis, risk assessment, and monitoring of autism spectrum disorders |
| CA2821908C (en) * | 2010-12-16 | 2018-09-18 | Autism Biotech Limited | Novel biomarker and uses thereof in diagnosis, treatment of autism |
| WO2014018468A1 (en) | 2012-07-22 | 2014-01-30 | Indiana University Research And Technology Corporation | Modulation sapp, sapp alpha and bdnf levels in individuals diagnosed with fxs and asd |
| PL3058371T3 (pl) | 2013-10-14 | 2021-11-08 | Indiana University Research And Technology Corporation | Zastosowanie akamprozatu do modulowania aktywacji erk 1-2 w modelach zwierzęcych dla fxs i asd oraz u osób z rozpoznaniem fxs i asd |
| CN105652016A (zh) * | 2016-01-28 | 2016-06-08 | 深圳大学 | 一种孤独症检测标志物及其检测方法 |
| US11131681B2 (en) * | 2017-03-10 | 2021-09-28 | Dr. Raymond Laboratories, Inc. | Method for diagnosing psychiatric disorders |
| WO2018164536A1 (ko) | 2017-03-10 | 2018-09-13 | 스핑고브레인 주식회사 | 정신장애의 진단 방법 |
| RU2643760C1 (ru) * | 2017-08-07 | 2018-02-05 | Федеральное государственное бюджетное научное учреждение "Научный центр психического здоровья" | Способ определения необходимости использования психофармакотерапии у пациентов с расстройствами аутистического спектра на момент их обследования |
| KR20190106442A (ko) | 2018-03-09 | 2019-09-18 | 스핑고브레인 주식회사 | 태지, 양수 또는 제대혈을 이용한 정신장애의 진단 방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2273683A1 (en) * | 1998-06-15 | 1999-12-15 | Ortho-Clinical Diagnostics, Inc. | Diagnostic markers for human disorders |
| IT1303675B1 (it) * | 1998-08-04 | 2001-02-23 | Radim S P A | Metodo di determinazione di peptidi utilizzati come marker per ladiagnosi dell'autismo |
| CA2387801A1 (en) | 1999-11-04 | 2001-05-10 | Human Genome Sciences, Inc. | Uteroglobin-like polynucleotides, polypeptides, and antibodies |
| US6998243B2 (en) | 2001-04-30 | 2006-02-14 | Syn X Pharma, Inc. | Biopolymer marker indicative of disease state having a molecular weight of 1793 daltons |
-
2003
- 2003-03-04 SE SE0300586A patent/SE0300586L/xx not_active Application Discontinuation
-
2004
- 2004-03-02 KR KR1020057016254A patent/KR101096487B1/ko not_active IP Right Cessation
- 2004-03-02 NZ NZ542149A patent/NZ542149A/en not_active IP Right Cessation
- 2004-03-02 CA CA2518066A patent/CA2518066C/en not_active Expired - Fee Related
- 2004-03-02 DK DK04716392T patent/DK1608982T3/da active
- 2004-03-02 WO PCT/SE2004/000193 patent/WO2004079371A1/en active IP Right Grant
- 2004-03-02 ES ES04716392T patent/ES2293234T3/es not_active Expired - Lifetime
- 2004-03-02 EP EP04716392A patent/EP1608982B9/en not_active Expired - Lifetime
- 2004-03-02 DE DE602004008439T patent/DE602004008439T2/de not_active Expired - Lifetime
- 2004-03-02 BR BRPI0408067-0A patent/BRPI0408067A/pt not_active IP Right Cessation
- 2004-03-02 RU RU2005130641/15A patent/RU2340900C2/ru not_active IP Right Cessation
- 2004-03-02 AT AT04716392T patent/ATE371192T1/de active
- 2004-03-02 CN CN2004800058238A patent/CN1795386B/zh not_active Expired - Fee Related
- 2004-03-02 JP JP2006507920A patent/JP4452715B2/ja not_active Expired - Fee Related
- 2004-03-02 AU AU2004217571A patent/AU2004217571B2/en not_active Ceased
- 2004-03-02 PL PL04716392T patent/PL1608982T3/pl unknown
- 2004-03-02 PT PT04716392T patent/PT1608982E/pt unknown
-
2005
- 2005-09-02 ZA ZA200507082A patent/ZA200507082B/en unknown
-
2011
- 2011-06-22 US US13/166,143 patent/US8268576B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1608982B9 (en) | 2008-07-23 |
| EP1608982B1 (en) | 2007-08-22 |
| PL1608982T3 (pl) | 2008-01-31 |
| PT1608982E (pt) | 2007-11-09 |
| RU2340900C2 (ru) | 2008-12-10 |
| AU2004217571B2 (en) | 2009-03-12 |
| KR20060006774A (ko) | 2006-01-19 |
| ES2293234T3 (es) | 2008-03-16 |
| CA2518066C (en) | 2011-05-10 |
| US8268576B2 (en) | 2012-09-18 |
| ATE371192T1 (de) | 2007-09-15 |
| CN1795386A (zh) | 2006-06-28 |
| DK1608982T3 (da) | 2007-11-26 |
| US20120149038A1 (en) | 2012-06-14 |
| ZA200507082B (en) | 2007-02-28 |
| CN1795386B (zh) | 2010-08-25 |
| DE602004008439T2 (de) | 2008-05-21 |
| CA2518066A1 (en) | 2004-09-16 |
| KR101096487B1 (ko) | 2011-12-20 |
| WO2004079371A1 (en) | 2004-09-16 |
| JP2006519391A (ja) | 2006-08-24 |
| JP4452715B2 (ja) | 2010-04-21 |
| EP1608982A1 (en) | 2005-12-28 |
| SE0300586L (sv) | 2004-09-05 |
| AU2004217571A1 (en) | 2004-09-16 |
| SE0300586D0 (sv) | 2003-03-04 |
| NZ542149A (en) | 2008-03-28 |
| DE602004008439D1 (de) | 2007-10-04 |
| BRPI0408067A (pt) | 2006-02-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US8268576B2 (en) | Diagnosis of autism | |
| Perry et al. | Amyotrophic lateral sclerosis: amino acid levels in plasma and cerebrospinal fluid | |
| RU2010135526A (ru) | Новый способ количественного определения и охарактеризования микровезикул в жидкостях организма человека | |
| JP2011510309A5 (ru) | ||
| RU2014123987A (ru) | Анализ адромедуллина и способы определения зрелого адромедуллина | |
| RU2012120706A (ru) | Диагностические и терапевтические способы | |
| RU2015116674A (ru) | Способ диагностики или мониторинга почечной функции или диагностики почечной дисфункции | |
| CN108398503A (zh) | 一种乳铁蛋白的液相色谱质谱检测方法 | |
| US20110160434A1 (en) | Fibromyalgia test method | |
| US8420331B2 (en) | Type IV collagen-like immunoreactive peptide | |
| RU2014102721A (ru) | Способ получения агента, связывающегося с препро-вазопрессином или с его фрагментами | |
| US10175250B2 (en) | Nitrated cardiac troponin I as a biomarker of cardiac ischemia | |
| JP2009244225A (ja) | 脳炎の診断方法及び脳炎の診断システム | |
| TWI606060B (zh) | 用於檢測神經性乙醯膽鹼受器阿爾法七次單位抗體之多肽分子 | |
| JP2024029191A (ja) | 認知症又はそのリスクの検査方法 | |
| CN111537749A (zh) | Myh9在制备重度少弱精症诊断试剂中的应用 | |
| JP2020064051A (ja) | 神経変性疾患の診断用ペプチドマーカー |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20130303 |