RU2004117534A - Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора v - Google Patents
Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора v Download PDFInfo
- Publication number
- RU2004117534A RU2004117534A RU2004117534/15A RU2004117534A RU2004117534A RU 2004117534 A RU2004117534 A RU 2004117534A RU 2004117534/15 A RU2004117534/15 A RU 2004117534/15A RU 2004117534 A RU2004117534 A RU 2004117534A RU 2004117534 A RU2004117534 A RU 2004117534A
- Authority
- RU
- Russia
- Prior art keywords
- factor
- factor vii
- vii
- polypeptide
- polypeptide related
- Prior art date
Links
- 229940012413 factor vii Drugs 0.000 title claims 61
- 229920001184 polypeptide Polymers 0.000 title claims 56
- 108090000765 processed proteins & peptides Proteins 0.000 title claims 56
- 102000004196 processed proteins & peptides Human genes 0.000 title claims 56
- 239000008194 pharmaceutical composition Substances 0.000 title claims 2
- 108010014172 Factor V Proteins 0.000 claims 70
- 102100023804 Coagulation factor VII Human genes 0.000 claims 60
- 108010023321 Factor VII Proteins 0.000 claims 60
- 239000000203 mixture Substances 0.000 claims 19
- 239000002552 dosage form Substances 0.000 claims 13
- 230000000694 effects Effects 0.000 claims 10
- 239000003814 drug Substances 0.000 claims 9
- 208000032843 Hemorrhage Diseases 0.000 claims 8
- 208000034158 bleeding Diseases 0.000 claims 8
- 230000000740 bleeding effect Effects 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 229940079593 drug Drugs 0.000 claims 7
- 108010054265 Factor VIIa Proteins 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 229940012414 factor viia Drugs 0.000 claims 4
- 229940099816 human factor vii Drugs 0.000 claims 4
- 238000002347 injection Methods 0.000 claims 4
- 239000007924 injection Substances 0.000 claims 4
- 230000009089 cytolysis Effects 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- 230000023597 hemostasis Effects 0.000 claims 2
- 238000001802 infusion Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 108010039209 Blood Coagulation Factors Proteins 0.000 claims 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 claims 1
- 206010053567 Coagulopathies Diseases 0.000 claims 1
- 230000023555 blood coagulation Effects 0.000 claims 1
- 239000003114 blood coagulation factor Substances 0.000 claims 1
- 230000035602 clotting Effects 0.000 claims 1
- 230000015271 coagulation Effects 0.000 claims 1
- 238000005345 coagulation Methods 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 108010047303 von Willebrand Factor Proteins 0.000 claims 1
- 102100036537 von Willebrand factor Human genes 0.000 claims 1
- 229960001134 von willebrand factor Drugs 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200101660 | 2001-11-09 | ||
| DKPA200101660 | 2001-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2004117534A true RU2004117534A (ru) | 2005-05-10 |
Family
ID=8160820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004117534/15A RU2004117534A (ru) | 2001-11-09 | 2002-11-05 | Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора v |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1446149A1 (cs) |
| JP (1) | JP2005511599A (cs) |
| KR (1) | KR20050043734A (cs) |
| CN (1) | CN1596125A (cs) |
| AU (1) | AU2002340779B2 (cs) |
| BR (1) | BR0213953A (cs) |
| CA (1) | CA2464615A1 (cs) |
| CZ (1) | CZ2004543A3 (cs) |
| HU (1) | HUP0401985A3 (cs) |
| IL (1) | IL161544A0 (cs) |
| MX (1) | MXPA04004304A (cs) |
| NO (1) | NO20042380L (cs) |
| PL (1) | PL370634A1 (cs) |
| RU (1) | RU2004117534A (cs) |
| WO (1) | WO2003039584A1 (cs) |
| ZA (1) | ZA200403271B (cs) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0302052A3 (en) | 1999-07-14 | 2005-12-28 | Novo Nordisk Healthcare Ag | Use of fviia or a tissue factor antagonist for regulating gene expression and cell migration or chemotaxis |
| ES2381110T3 (es) | 2003-09-09 | 2012-05-23 | Novo Nordisk Health Care Ag | Polipéptidos de factor VII de coagulación |
| EP1713496A1 (en) * | 2004-02-05 | 2006-10-25 | Novo Nordisk Health Care AG | Use of factor viia for treating trauma |
| FR2894831B1 (fr) * | 2005-12-16 | 2008-02-15 | Lab Francais Du Fractionnement | Colle biologique exempte de thrombine et son utilisation comme medicament. |
| DK2004214T3 (da) | 2006-03-16 | 2013-02-18 | Stellaris Pharmaceuticals Aps | Lokalbehandling med faktor VII |
| EP3065768B1 (en) * | 2013-11-04 | 2020-09-23 | The Regents of the University of California | Composition for use in treatment or prevention of conditions associated with bleeding or hypocoagulationcompostion |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6083905A (en) * | 1994-04-22 | 2000-07-04 | Stichting Sanquin Bloedvoorziening | Method and means for detecting and treating disorders in the blood coagulation cascade |
| AU7907398A (en) * | 1997-06-23 | 1999-01-04 | Novo Nordisk A/S | Use of fviia for the treatment of bleedings in patients with a normal blood clotting cascade and normal platelet function |
| JP2002514433A (ja) * | 1998-05-14 | 2002-05-21 | バッテル メモリアル インスティテュート | トランスジェニック植物由来ヒト凝血因子 |
-
2002
- 2002-11-05 BR BR0213953-7A patent/BR0213953A/pt not_active IP Right Cessation
- 2002-11-05 CA CA002464615A patent/CA2464615A1/en not_active Abandoned
- 2002-11-05 JP JP2003541875A patent/JP2005511599A/ja not_active Withdrawn
- 2002-11-05 EP EP02774475A patent/EP1446149A1/en not_active Withdrawn
- 2002-11-05 AU AU2002340779A patent/AU2002340779B2/en not_active Ceased
- 2002-11-05 KR KR1020047006607A patent/KR20050043734A/ko not_active Ceased
- 2002-11-05 CN CNA028237269A patent/CN1596125A/zh active Pending
- 2002-11-05 CZ CZ2004543A patent/CZ2004543A3/cs unknown
- 2002-11-05 IL IL16154402A patent/IL161544A0/xx unknown
- 2002-11-05 PL PL02370634A patent/PL370634A1/xx not_active Application Discontinuation
- 2002-11-05 RU RU2004117534/15A patent/RU2004117534A/ru not_active Application Discontinuation
- 2002-11-05 MX MXPA04004304A patent/MXPA04004304A/es active IP Right Grant
- 2002-11-05 HU HU0401985A patent/HUP0401985A3/hu unknown
- 2002-11-05 WO PCT/DK2002/000736 patent/WO2003039584A1/en not_active Ceased
-
2004
- 2004-04-30 ZA ZA200403271A patent/ZA200403271B/en unknown
- 2004-06-08 NO NO20042380A patent/NO20042380L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050043734A (ko) | 2005-05-11 |
| WO2003039584A1 (en) | 2003-05-15 |
| HUP0401985A3 (en) | 2009-03-30 |
| HUP0401985A2 (hu) | 2004-12-28 |
| BR0213953A (pt) | 2004-08-31 |
| JP2005511599A (ja) | 2005-04-28 |
| CN1596125A (zh) | 2005-03-16 |
| AU2002340779B2 (en) | 2007-08-02 |
| NO20042380L (no) | 2004-06-08 |
| MXPA04004304A (es) | 2004-08-11 |
| CZ2004543A3 (cs) | 2004-08-18 |
| CA2464615A1 (en) | 2003-05-15 |
| IL161544A0 (en) | 2004-09-27 |
| EP1446149A1 (en) | 2004-08-18 |
| ZA200403271B (en) | 2004-11-08 |
| PL370634A1 (en) | 2005-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20080326 |