RU2002126553A - Композиции, содержащие миноксидил - Google Patents

Композиции, содержащие миноксидил

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Publication number
RU2002126553A
RU2002126553A RU2002126553/15A RU2002126553A RU2002126553A RU 2002126553 A RU2002126553 A RU 2002126553A RU 2002126553/15 A RU2002126553/15 A RU 2002126553/15A RU 2002126553 A RU2002126553 A RU 2002126553A RU 2002126553 A RU2002126553 A RU 2002126553A
Authority
RU
Russia
Prior art keywords
minoxidil
composition
dibutylhydroxytoluene
butylhydroxyanisole
minoxidyl
Prior art date
Application number
RU2002126553/15A
Other languages
English (en)
Other versions
RU2275914C2 (ru
Inventor
Кодзи ИМАМУРА (JP)
Кодзи ИМАМУРА
Руми ОТИАЙ (JP)
Руми ОТИАЙ
Такако ОКАДЗИМА (JP)
Такако ОКАДЗИМА
Сусуму МОРИОКА (JP)
Сусуму МОРИОКА
Таро ХОРИЕ (JP)
Таро ХОРИЕ
Original Assignee
Тайсо Фармасьютикал Ко., Лтд. (Jp)
Тайсо Фармасьютикал Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Тайсо Фармасьютикал Ко., Лтд. (Jp), Тайсо Фармасьютикал Ко., Лтд. filed Critical Тайсо Фармасьютикал Ко., Лтд. (Jp)
Publication of RU2002126553A publication Critical patent/RU2002126553A/ru
Application granted granted Critical
Publication of RU2275914C2 publication Critical patent/RU2275914C2/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4966—Triazines or their condensed derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Claims (6)

1. Композиция, содержащая миноксидил, которая включает одно или два соединения, выбранные их группы, включающей дибутилгидрокситолуол и бутилгидроксианизол, и имеет концентрацию миноксидила от 3 до 6 мас.% и рН от 5,5 до 7,0.
2. Композиция, содержащая миноксидил, которая включает одно или два соединения, выбранные из группы, включающей дибутилгидрокситолуол и бутилгидроксианизол, имеет концентрацию миноксидила от 3 до 6 мас.% и рН от 5,7 до 6,3.
3. Композиция, содержащая миноксидил, по любому из пп.1 и 2, которая включает одно или два соединения, выбранные из группы, включающей дибутилгидрокситолуол и бутилгидроксианизол в количестве от 0,005 до 0,5 мас.ч. в расчете на одну мас.ч. миноксидила.
4. Композиция, содержащая миноксидил, по любому из пп.1-3, которая дополнительно включает многоатомный спирт.
5. Композиция, содержащая миноксидил, по любому из пп.1-3, которая дополнительно включает полиэтиленгликоль.
6. Способ предотвращения окрашивания композиции, содержащей миноксидил, который включает введение в композицию одного или двух соединений, выбранных из группы, включающей дибутилгидрокситолуол и бутилгидроксианизол, и доведение рН композиции до величины от 5,5 до 7,0.
RU2002126553/15A 2000-04-07 2001-04-05 Композиции, содержащие миноксидил RU2275914C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000107028A JP4780429B2 (ja) 2000-04-07 2000-04-07 ミノキシジル含有製剤
JP2000-107028 2000-04-07

Publications (2)

Publication Number Publication Date
RU2002126553A true RU2002126553A (ru) 2004-03-20
RU2275914C2 RU2275914C2 (ru) 2006-05-10

Family

ID=18620086

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002126553/15A RU2275914C2 (ru) 2000-04-07 2001-04-05 Композиции, содержащие миноксидил

Country Status (18)

Country Link
EP (1) EP1273299B1 (ru)
JP (1) JP4780429B2 (ru)
KR (1) KR100740393B1 (ru)
CN (1) CN1279914C (ru)
AT (1) ATE306925T1 (ru)
AU (1) AU778783B2 (ru)
BR (1) BR0109847A (ru)
CA (1) CA2405429C (ru)
DE (1) DE60114171T2 (ru)
DK (1) DK1273299T3 (ru)
ES (1) ES2250374T3 (ru)
HK (1) HK1056510A1 (ru)
HU (1) HUP0301124A2 (ru)
NZ (1) NZ521733A (ru)
RU (1) RU2275914C2 (ru)
TW (1) TWI239842B (ru)
WO (1) WO2001076605A1 (ru)
ZA (1) ZA200207960B (ru)

Families Citing this family (27)

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AUPO983897A0 (en) 1997-10-17 1997-11-06 Soltec Research Pty Ltd Topical antifungal composition
AUPP310798A0 (en) 1998-04-22 1998-05-14 Soltec Research Pty Ltd Vehicle system for a composition comprising a piperidinopyrimidine derivative
JP5785353B2 (ja) * 2004-02-27 2015-09-30 大正製薬株式会社 眼科用剤
TW200534875A (en) * 2004-04-23 2005-11-01 Lonza Ag Personal care compositions and concentrates for making the same
JP2006022091A (ja) * 2004-06-09 2006-01-26 Dai Ichi Seiyaku Co Ltd 育毛用組成物
JP5040060B2 (ja) * 2004-10-14 2012-10-03 大正製薬株式会社 メチオニン配合内服液剤
RU2457826C2 (ru) * 2006-12-20 2012-08-10 Тайсо Фармасьютикал Ко., Лтд. Профилактическое или терапевтическое средство от алопеции
US20090175810A1 (en) 2008-01-03 2009-07-09 Gareth Winckle Compositions and methods for treating diseases of the nail
JP5286999B2 (ja) * 2008-07-10 2013-09-11 大正製薬株式会社 ミノキシジル含有液剤
JP2012504135A (ja) * 2008-09-27 2012-02-16 ジャイナ ファーマシューティカルズ，インコーポレーテッド 経口適用および局所適用のための脂質系薬学的調製物、ならびにそれらの組成物、方法、および使用
US8470833B2 (en) 2009-12-15 2013-06-25 Mcneil-Ppc, Inc. Hair growth and/or regrowth compositions
US8039494B1 (en) 2010-07-08 2011-10-18 Dow Pharmaceutical Sciences, Inc. Compositions and methods for treating diseases of the nail
JP6067036B2 (ja) * 2013-01-31 2017-01-25 富士フイルム株式会社 乳化組成物
JP6199066B2 (ja) * 2013-04-24 2017-09-20 ロート製薬株式会社 ミノキシジル含有外用組成物
KR101580119B1 (ko) * 2013-04-29 2015-12-29 한국유나이티드제약 주식회사 쓴맛이 차폐된 황련 추출물을 포함하는 경구투여용 제제
MX363386B (es) * 2013-10-03 2019-03-20 Dow Pharmaceutical Sciences Formulaciones de efinaconazol estabilizadas.
KR20160087898A (ko) 2013-11-22 2016-07-22 다우 파마슈티컬 사이언시즈, 인코포레이티드 항­감염 방법，조성물，및 장치
JP6736889B2 (ja) * 2015-01-23 2020-08-05 大正製薬株式会社 外用組成物
JP6528194B2 (ja) * 2015-02-06 2019-06-12 ダイヤ製薬株式会社 ミノキシジル含有外用液剤および外用液剤の製造方法
JP6052686B2 (ja) * 2015-02-06 2016-12-27 ダイヤ製薬株式会社 外用液剤
JP6825354B2 (ja) * 2015-12-29 2021-02-03 大正製薬株式会社 外用組成物
JP7346010B2 (ja) * 2016-09-15 2023-09-19 大正製薬株式会社 外用組成物
KR102000217B1 (ko) * 2017-08-08 2019-07-15 에스씨엠생명과학 주식회사 Cxcl1 단백질 및 미녹시딜을 유효성분으로 포함하는 탈모 예방 또는 치료용 약학적 조성물
JP2017206558A (ja) * 2017-08-22 2017-11-24 ロート製薬株式会社 ミノキシジル含有外用組成物
JP2020023467A (ja) * 2018-01-19 2020-02-13 ロート製薬株式会社 外用製剤、液切れ性を改善する方法、および、液切れ性改善剤
JP7304463B2 (ja) * 2018-01-29 2023-07-06 富士化学工業株式会社 ミノキシジル含有外用組成物
JP2019014764A (ja) * 2018-11-06 2019-01-31 ロート製薬株式会社 ミノキシジル含有外用組成物

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FR2641184B1 (fr) * 1988-12-30 1991-04-05 Oreal Composition pour induire et stimuler la croissance des cheveux et/ou freiner leur chute, a base de derives de pyrimidine et de filtres solaires
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JPH11349451A (ja) * 1998-06-08 1999-12-21 Taisho Pharmaceut Co Ltd 育毛剤

Also Published As

Publication number Publication date
ATE306925T1 (de) 2005-11-15
CA2405429C (en) 2007-09-04
CN1279914C (zh) 2006-10-18
JP4780429B2 (ja) 2011-09-28
NZ521733A (en) 2003-08-29
CN1431903A (zh) 2003-07-23
JP2001288090A (ja) 2001-10-16
EP1273299A4 (en) 2003-05-14
EP1273299A1 (en) 2003-01-08
AU4683901A (en) 2001-10-23
EP1273299B1 (en) 2005-10-19
DE60114171D1 (de) 2006-03-02
ZA200207960B (en) 2004-01-27
BR0109847A (pt) 2003-06-24
TWI239842B (en) 2005-09-21
KR20020087126A (ko) 2002-11-21
DE60114171T2 (de) 2006-07-06
AU778783B2 (en) 2004-12-23
CA2405429A1 (en) 2001-10-18
WO2001076605A1 (fr) 2001-10-18
RU2275914C2 (ru) 2006-05-10
DK1273299T3 (da) 2006-02-06
ES2250374T3 (es) 2006-04-16
KR100740393B1 (ko) 2007-07-16
HK1056510A1 (en) 2004-02-20
HUP0301124A2 (hu) 2003-08-28

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