RU2002112238A - Перорально распадающаяся композиция, содержащая миртазапин - Google Patents

Перорально распадающаяся композиция, содержащая миртазапин

Info

Publication number
RU2002112238A
RU2002112238A RU2002112238/15A RU2002112238A RU2002112238A RU 2002112238 A RU2002112238 A RU 2002112238A RU 2002112238/15 A RU2002112238/15 A RU 2002112238/15A RU 2002112238 A RU2002112238 A RU 2002112238A RU 2002112238 A RU2002112238 A RU 2002112238A
Authority
RU
Russia
Prior art keywords
mirtazapine
dosage form
unit dosage
oral
decompositive
Prior art date
Application number
RU2002112238/15A
Other languages
English (en)
Other versions
RU2261098C2 (ru
Inventor
НЕЙС Хенрик ДЕ (NL)
НЕЙС Хенрик ДЕ
Original Assignee
Акцо Нобель Н.В. (NL)
Акцо Нобель Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8240737&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2002112238(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Акцо Нобель Н.В. (NL), Акцо Нобель Н.В. filed Critical Акцо Нобель Н.В. (NL)
Publication of RU2002112238A publication Critical patent/RU2002112238A/ru
Application granted granted Critical
Publication of RU2261098C2 publication Critical patent/RU2261098C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Claims (5)

1. Единичная дозированная лекарственная форма для перорального введения, включающая фармацевтический состав миртазапина в качестве активного вещества и фармацевтически приемлемые наполнители, отличающаяся тем, что единичная дозированная лекарственная форма является перорально распадающейся и включает средство, которое, в основном, предохраняет миртазапин от перорального высвобождения.
2. Единичная дозированная лекарственная форма по п.1, отличающаяся тем, что средство, которое предохраняет миртазапин от перорального высвобождения, представляет слой полимера, покрывающий миртазапин.
3. Единичная дозированная лекарственная форма по п.2, отличающаяся тем, что полимером является Eudragit E100.
4. Единичная дозированная лекарственная форма по п.2, отличающаяся тем, что миртазапин, в свою очередь, нанесен на инертные частицы.
5. Единичная дозированная лекарственная форма по п.4, отличающаяся тем, что частицы представляют однородные по размеру частицы сферической формы (non-pareils).
RU2002112238/15A 1999-10-13 2000-10-09 Перорально распадающаяся композиция, содержащая миртазапин RU2261098C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99203338.1 1999-10-13
EP99203338 1999-10-13

Publications (2)

Publication Number Publication Date
RU2002112238A true RU2002112238A (ru) 2004-01-10
RU2261098C2 RU2261098C2 (ru) 2005-09-27

Family

ID=8240737

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002112238/15A RU2261098C2 (ru) 1999-10-13 2000-10-09 Перорально распадающаяся композиция, содержащая миртазапин

Country Status (28)

Country Link
EP (1) EP1223914B1 (ru)
JP (1) JP5561885B2 (ru)
KR (1) KR100708560B1 (ru)
CN (1) CN1173701C (ru)
AR (1) AR026010A1 (ru)
AT (1) ATE274899T1 (ru)
AU (1) AU780379B2 (ru)
BR (1) BR0014593A (ru)
CA (1) CA2386547C (ru)
CO (1) CO5251412A1 (ru)
CZ (1) CZ20021315A3 (ru)
DE (2) DE1223914T1 (ru)
ES (1) ES2194618T3 (ru)
HK (1) HK1046641B (ru)
HU (1) HUP0203148A3 (ru)
IL (2) IL148777A0 (ru)
MX (1) MXPA02003519A (ru)
NO (1) NO20021730L (ru)
NZ (1) NZ518165A (ru)
PE (1) PE20010699A1 (ru)
PL (1) PL200858B1 (ru)
PT (1) PT1223914E (ru)
RU (1) RU2261098C2 (ru)
SK (1) SK6452002A3 (ru)
TR (1) TR200200978T2 (ru)
TW (1) TWI256309B (ru)
WO (1) WO2001026621A2 (ru)
ZA (1) ZA200202293B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005051349A2 (en) * 2003-11-25 2005-06-09 Aurobindo Pharma Ltd. Pharmaceutical compositions of mirtazapine
DE102004034043A1 (de) * 2004-07-13 2006-02-09 Krka Tovarna Zdravil, D.D. Feste pharmazeutische Zusammensetzung, die Mirtazapin enthält
AU2007221135A1 (en) * 2006-02-27 2007-09-07 Alexander Michalow Methods for regulating neurotransmitter systems by inducing counteradaptations
CN101129341B (zh) * 2006-08-22 2011-06-01 上海医药工业研究院 口内崩解组合物及其制备方法
EP2377522B1 (en) 2010-04-15 2013-01-16 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Orally disintegrating tablet formulations of mirtazapine and process for preparing the same
CN102993208B (zh) * 2011-11-22 2017-01-18 北京哈三联科技股份有限公司 去甲肾上腺素和选择性五羟色胺受体阻断剂及其应用
JP6199321B2 (ja) * 2012-03-02 2017-09-20 ローズ ファーマシューティカルズ エル．ピー． 不正使用抵抗性の即時放出製剤
CN104095824B (zh) * 2013-04-09 2016-08-31 上海信谊万象药业股份有限公司 一种米氮平缓释片及其制备方法
PL3261645T3 (pl) 2015-02-27 2021-12-06 Dechra Limited Pobudzanie apetytu, zarządzanie utratą masy ciała, i leczenie anoreksji u psów i kotów
JP6601844B2 (ja) * 2016-12-05 2019-11-06 共和薬品工業株式会社 光安定性に優れたミルタザピン含有医薬製剤
CN111714463B (zh) * 2020-08-14 2022-06-17 华农（肇庆）生物产业技术研究院有限公司 米氮平口服剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8724763D0 (en) * 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations
US5178878A (en) * 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles
ES2097155T3 (es) * 1989-10-02 1997-04-01 Cima Labs Inc Forma de dosificacion efervescente y metodo de administracion.
IE63986B1 (en) * 1989-12-30 1995-06-28 Akzo Nv Pharmaceutical preparation for oral administration in fluid form
JPH0436252A (ja) * 1990-05-30 1992-02-06 Nippon Alkyl Alum Kk 光学活性アルキニルアルコールの製造方法
JP3168695B2 (ja) * 1991-06-14 2001-05-21 三菱化学株式会社 ショ糖脂肪酸エステルの置換度の低下方法
US5464632C1 (en) * 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
JPH05163137A (ja) * 1991-12-12 1993-06-29 Shin Etsu Chem Co Ltd 有核顆粒
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
JPH0737473A (ja) * 1993-07-27 1995-02-07 Murata Mfg Co Ltd 圧力スイッチ
JPH10139659A (ja) * 1996-09-10 1998-05-26 Freunt Ind Co Ltd 球形粒子群、その製造方法及びそれを用いた球形粒子製剤
JP3870470B2 (ja) * 1997-02-07 2007-01-17 大正製薬株式会社 マルチプルユニットタイプ徐放性錠剤

Also Published As

Publication number Publication date
ES2194618T3 (es) 2005-04-01
CN1378452A (zh) 2002-11-06
ZA200202293B (en) 2003-06-20
DE60013466T2 (de) 2005-01-20
HK1046641A1 (en) 2003-01-24
IL148777A0 (en) 2002-09-12
ES2194618T1 (es) 2003-12-01
EP1223914B1 (en) 2004-09-01
TWI256309B (en) 2006-06-11
NZ518165A (en) 2004-03-26
DE1223914T1 (de) 2003-09-18
AU780379B2 (en) 2005-03-17
KR100708560B1 (ko) 2007-04-19
IL148777A (en) 2013-10-31
NO20021730D0 (no) 2002-04-12
PE20010699A1 (es) 2001-07-06
AR026010A1 (es) 2002-12-26
AU1023201A (en) 2001-04-23
RU2261098C2 (ru) 2005-09-27
SK6452002A3 (en) 2002-09-10
ATE274899T1 (de) 2004-09-15
CO5251412A1 (es) 2003-02-28
EP1223914A2 (en) 2002-07-24
HK1046641B (zh) 2005-04-08
CZ20021315A3 (cs) 2002-07-17
PL354584A1 (en) 2004-01-26
TR200200978T2 (tr) 2002-09-23
CN1173701C (zh) 2004-11-03
CA2386547A1 (en) 2001-04-19
WO2001026621A2 (en) 2001-04-19
CA2386547C (en) 2010-06-08
HUP0203148A2 (hu) 2003-01-28
JP5561885B2 (ja) 2014-07-30
JP2003511403A (ja) 2003-03-25
BR0014593A (pt) 2002-06-11
HUP0203148A3 (en) 2004-06-28
PT1223914E (pt) 2004-11-30
PL200858B1 (pl) 2009-02-27
KR20020038946A (ko) 2002-05-24
MXPA02003519A (es) 2002-08-20
NO20021730L (no) 2002-05-30
DE60013466D1 (de) 2004-10-07
WO2001026621A3 (en) 2001-10-11

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Legal Events

Date Code Title Description
PC4A Invention patent assignment

Effective date: 20070411

PC43 Official registration of the transfer of the exclusive right without contract for inventions

Effective date: 20120326

PC43 Official registration of the transfer of the exclusive right without contract for inventions

Effective date: 20130917

PC43 Official registration of the transfer of the exclusive right without contract for inventions

Effective date: 20140402