RU2002106874A - Фармацевтические композиции для лечения псориаза - Google Patents
Фармацевтические композиции для лечения псориаза Download PDFInfo
- Publication number
- RU2002106874A RU2002106874A RU2002106874/14A RU2002106874A RU2002106874A RU 2002106874 A RU2002106874 A RU 2002106874A RU 2002106874/14 A RU2002106874/14 A RU 2002106874/14A RU 2002106874 A RU2002106874 A RU 2002106874A RU 2002106874 A RU2002106874 A RU 2002106874A
- Authority
- RU
- Russia
- Prior art keywords
- dexrazoxane
- infusion
- hydrochloride
- injection
- terms
- Prior art date
Links
- 201000004681 Psoriasis Diseases 0.000 title claims 6
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- BMKDZUISNHGIBY-ZETCQYMHSA-N (+)-dexrazoxane Chemical compound C([C@H](C)N1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1 BMKDZUISNHGIBY-ZETCQYMHSA-N 0.000 claims 37
- 229960000605 dexrazoxane Drugs 0.000 claims 37
- 238000000034 method Methods 0.000 claims 15
- 238000001802 infusion Methods 0.000 claims 13
- 238000002347 injection Methods 0.000 claims 13
- 239000007924 injection Substances 0.000 claims 13
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 11
- 239000003814 drug Substances 0.000 claims 8
- 229940079593 drug Drugs 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 2
- 229960004102 dexrazoxane hydrochloride Drugs 0.000 claims 2
- BIFMNMPSIYHKDN-FJXQXJEOSA-N dexrazoxane hydrochloride Chemical compound [H+].[Cl-].C([C@H](C)N1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1 BIFMNMPSIYHKDN-FJXQXJEOSA-N 0.000 claims 2
- 239000006210 lotion Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000002674 ointment Substances 0.000 claims 2
- 238000007911 parenteral administration Methods 0.000 claims 2
- 239000001294 propane Substances 0.000 claims 2
- 239000000829 suppository Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 239000012049 topical pharmaceutical composition Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT155899 | 1999-09-10 | ||
| ATA1558/99 | 1999-09-10 | ||
| US18380600P | 2000-02-22 | 2000-02-22 | |
| US60/183,806 | 2000-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2002106874A true RU2002106874A (ru) | 2003-11-20 |
Family
ID=25596169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2002106874/14A RU2002106874A (ru) | 1999-09-10 | 2000-09-08 | Фармацевтические композиции для лечения псориаза |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1214073A2 (cs) |
| KR (1) | KR20020035131A (cs) |
| CN (1) | CN1378451A (cs) |
| AU (1) | AU7286500A (cs) |
| BG (1) | BG106428A (cs) |
| BR (1) | BR0013921A (cs) |
| CA (1) | CA2384685A1 (cs) |
| CZ (1) | CZ2002729A3 (cs) |
| EE (1) | EE04871B1 (cs) |
| HR (1) | HRPK20020201B1 (cs) |
| HU (1) | HUP0202791A3 (cs) |
| MX (1) | MXPA02002486A (cs) |
| PL (1) | PL354980A1 (cs) |
| RU (1) | RU2002106874A (cs) |
| SK (1) | SK2802002A3 (cs) |
| WO (1) | WO2001019358A2 (cs) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021053523A1 (en) * | 2019-09-18 | 2021-03-25 | Tryp Therapeutics | Compositions and methods to improve the therapeutic benefit of bis-dioxopiperazines |
| WO2023182298A1 (ja) | 2022-03-22 | 2023-09-28 | 国立大学法人京都大学 | 脆弱ｘ症候群の治療または予防薬 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1234935A (en) * | 1967-07-03 | 1971-06-09 | Nat Res Dev | Piperazine derivatives |
| US3941790A (en) * | 1967-07-03 | 1976-03-02 | National Research Development Corporation | Bis diketopiperazines |
| US4963679A (en) * | 1988-02-17 | 1990-10-16 | Erbamont, Inc. | Process for preparing bis (3,5-dioxopiperazinyl) alkanes or alkenes |
| KR960703597A (ko) * | 1993-07-23 | 1996-08-31 | 데이비드 엘 토메이 | 아폽토시스 및 관련 상태의 치료방법(methods of treating apoptosis and associated conditions) |
-
2000
- 2000-09-08 MX MXPA02002486A patent/MXPA02002486A/es unknown
- 2000-09-08 BR BR0013921-1A patent/BR0013921A/pt not_active Application Discontinuation
- 2000-09-08 AU AU72865/00A patent/AU7286500A/en not_active Abandoned
- 2000-09-08 KR KR1020027003049A patent/KR20020035131A/ko not_active Application Discontinuation
- 2000-09-08 RU RU2002106874/14A patent/RU2002106874A/ru not_active Application Discontinuation
- 2000-09-08 CA CA002384685A patent/CA2384685A1/en not_active Abandoned
- 2000-09-08 WO PCT/EP2000/008879 patent/WO2001019358A2/en not_active Application Discontinuation
- 2000-09-08 CZ CZ2002729A patent/CZ2002729A3/cs unknown
- 2000-09-08 EP EP00960646A patent/EP1214073A2/en not_active Withdrawn
- 2000-09-08 PL PL00354980A patent/PL354980A1/xx not_active Application Discontinuation
- 2000-09-08 SK SK280-2002A patent/SK2802002A3/sk not_active Application Discontinuation
- 2000-09-08 EE EEP200200128A patent/EE04871B1/xx not_active IP Right Cessation
- 2000-09-08 CN CN00812682A patent/CN1378451A/zh active Pending
- 2000-09-08 HU HU0202791A patent/HUP0202791A3/hu unknown
-
2002
- 2002-02-22 BG BG106428A patent/BG106428A/xx unknown
- 2002-03-05 HR HR20020201A patent/HRPK20020201B1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20020201A2 (en) | 2003-06-30 |
| HRPK20020201B1 (en) | 2004-08-31 |
| WO2001019358A2 (en) | 2001-03-22 |
| AU7286500A (en) | 2001-04-17 |
| KR20020035131A (ko) | 2002-05-09 |
| HUP0202791A3 (en) | 2003-02-28 |
| WO2001019358A3 (en) | 2001-10-04 |
| EP1214073A2 (en) | 2002-06-19 |
| EE04871B1 (et) | 2007-08-15 |
| MXPA02002486A (es) | 2004-09-10 |
| SK2802002A3 (en) | 2003-02-04 |
| EE200200128A (et) | 2003-04-15 |
| PL354980A1 (en) | 2004-03-22 |
| CZ2002729A3 (cs) | 2002-07-17 |
| HUP0202791A2 (hu) | 2003-01-28 |
| BG106428A (en) | 2003-04-30 |
| BR0013921A (pt) | 2002-05-14 |
| CN1378451A (zh) | 2002-11-06 |
| CA2384685A1 (en) | 2001-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20000908 |