RS69204A - Dihydro-thia-phenanthrene-carbonyl- guanidines,method for the production thereof,use therof as a medicament or diagnostic reagent - Google Patents

Dihydro-thia-phenanthrene-carbonyl- guanidines,method for the production thereof,use therof as a medicament or diagnostic reagent

Info

Publication number
RS69204A
RS69204A YU69204A YUP69204A RS69204A RS 69204 A RS69204 A RS 69204A YU 69204 A YU69204 A YU 69204A YU P69204 A YUP69204 A YU P69204A RS 69204 A RS69204 A RS 69204A
Authority
RS
Serbia
Prior art keywords
guanidines
thia
phenanthrene
dihydro
carbonyl
Prior art date
Application number
YU69204A
Other languages
English (en)
Inventor
Heinz-Werner Kleemann
Peter Below
Original Assignee
Sanofi-Aventis Deutschland Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis Deutschland Gmbh. filed Critical Sanofi-Aventis Deutschland Gmbh.
Publication of RS69204A publication Critical patent/RS69204A/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/10—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms two oxygen atoms and one sulfur atom, e.g. cyclic sulfates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Pronalazak se odnosi na dihidro-tia-fenantren-karbonil-gvanidine formule (I); u njoj R1 do R9 imaju značenja koja su navedena u patentnim zahtevima. Ova jedinjenja kao antiaritmijski medikamenti sa kardioprotektivnom komponentom su pogodna za profilaksu od infarkta i lečenje infarkta isto tako i za lečenje angine pektoris. Ona inhibiraju preventivno patofiziološke procese pri nastajanju oboljenja indukovanih ishemijom, naročito pri pojavi ishemijski indukovane srčane aritmije.
YU69204A 2002-02-07 2003-01-23 Dihydro-thia-phenanthrene-carbonyl- guanidines,method for the production thereof,use therof as a medicament or diagnostic reagent RS69204A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10204989A DE10204989A1 (de) 2002-02-07 2002-02-07 Dihydro-thia-phenanthren-carbonyl-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
PCT/EP2003/000653 WO2003066620A1 (de) 2002-02-07 2003-01-23 Dihydro-thia-phenanthren-carbonyl-guanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament oder diagnostikum

Publications (1)

Publication Number Publication Date
RS69204A true RS69204A (en) 2006-12-15

Family

ID=27618378

Family Applications (1)

Application Number Title Priority Date Filing Date
YU69204A RS69204A (en) 2002-02-07 2003-01-23 Dihydro-thia-phenanthrene-carbonyl- guanidines,method for the production thereof,use therof as a medicament or diagnostic reagent

Country Status (25)

Country Link
EP (1) EP1474414B1 (sr)
JP (1) JP4410564B2 (sr)
KR (1) KR20040096555A (sr)
CN (1) CN1319963C (sr)
AR (1) AR038393A1 (sr)
AT (1) ATE380805T1 (sr)
AU (1) AU2003208337A1 (sr)
BR (1) BR0307495A (sr)
CA (1) CA2475093A1 (sr)
CO (1) CO5601008A2 (sr)
DE (2) DE10204989A1 (sr)
HK (1) HK1073656A1 (sr)
HR (1) HRP20040721A2 (sr)
HU (1) HUP0402595A2 (sr)
MA (1) MA27171A1 (sr)
MX (1) MXPA04007476A (sr)
NO (1) NO20043717L (sr)
NZ (1) NZ534536A (sr)
PE (1) PE20030963A1 (sr)
PL (1) PL370271A1 (sr)
RS (1) RS69204A (sr)
RU (1) RU2306311C2 (sr)
TW (1) TWI268927B (sr)
WO (1) WO2003066620A1 (sr)
ZA (1) ZA200406015B (sr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200614995A (en) 2004-11-10 2006-05-16 Nicholas Piramal India Ltd Tricyclic guanidine derivatives as sodium-proton exchange inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60262887A (ja) * 1984-06-11 1985-12-26 Mitsubishi Chem Ind Ltd 液晶組成物
GB8505756D0 (en) * 1985-03-06 1985-04-11 Erba Farmitalia Tricyclic dibenzo condensed derivatives
US4948806A (en) * 1988-03-30 1990-08-14 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic compounds and compositions
DE19601303A1 (de) * 1996-01-16 1997-07-17 Boehringer Ingelheim Kg Neuartige Benzoylguanidin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung bei der Herstellung von Arzneimitteln
CA2370607A1 (en) * 1999-04-23 2000-11-02 Bristol-Myers Squibb Company Bicyclic acyl guanidine sodium/proton exchange inhibitors and method
DE10001879A1 (de) * 2000-01-19 2001-07-19 Aventis Pharma Gmbh Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
HUP0402595A2 (hu) 2005-04-28
BR0307495A (pt) 2004-12-28
NZ534536A (en) 2006-02-24
MA27171A1 (fr) 2005-01-03
AR038393A1 (es) 2005-01-12
DE10204989A1 (de) 2003-08-21
ZA200406015B (en) 2005-11-14
KR20040096555A (ko) 2004-11-16
WO2003066620A1 (de) 2003-08-14
AU2003208337A1 (en) 2003-09-02
NO20043717L (no) 2004-11-03
TW200404792A (en) 2004-04-01
MXPA04007476A (es) 2004-11-10
CA2475093A1 (en) 2003-08-14
TWI268927B (en) 2006-12-21
PE20030963A1 (es) 2004-01-12
PL370271A1 (en) 2005-05-16
CN1630649A (zh) 2005-06-22
HK1073656A1 (en) 2005-10-14
RU2306311C2 (ru) 2007-09-20
JP2005517015A (ja) 2005-06-09
CN1319963C (zh) 2007-06-06
JP4410564B2 (ja) 2010-02-03
EP1474414B1 (de) 2007-12-12
CO5601008A2 (es) 2006-01-31
ATE380805T1 (de) 2007-12-15
HRP20040721A2 (en) 2005-06-30
DE50308787D1 (de) 2008-01-24
RU2004126854A (ru) 2006-01-27
EP1474414A1 (de) 2004-11-10

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