CO5601008A2 - Dihidrotiafenantrencarbonilguanidinas, proceso para su preparacion, su uso como medicamento o auxiliar de diagnostico y medicamentos que las comprenden - Google Patents
Dihidrotiafenantrencarbonilguanidinas, proceso para su preparacion, su uso como medicamento o auxiliar de diagnostico y medicamentos que las comprendenInfo
- Publication number
- CO5601008A2 CO5601008A2 CO04076743A CO04076743A CO5601008A2 CO 5601008 A2 CO5601008 A2 CO 5601008A2 CO 04076743 A CO04076743 A CO 04076743A CO 04076743 A CO04076743 A CO 04076743A CO 5601008 A2 CO5601008 A2 CO 5601008A2
- Authority
- CO
- Colombia
- Prior art keywords
- carbon atoms
- alkyl
- hydrogen
- independently
- zero
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/10—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms two oxygen atoms and one sulfur atom, e.g. cyclic sulfates
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1.- Una dihidrotiafenantrencarbonilguanidina de fórmula Ien la que los significados son:R(1) y R(3) independientemente entre sí hidrógeno, alquilo de 1, 2, 3 ó 4 átomos de carbono, alcoxi de 1, 2, 3, ó 4 átomos de carbono, F, Cl, Br, I, CN, NR (10) R (11), -Op-(CH2)n- (CF2)x -CF3 o - (SOm)p - (CH2)n-(CF2)x-CF3;R(10) y R(11) independientemente entre sí hidrógeno, alquilo de 1, 2, 3 ó 4 átomos de carbono o - (CH2)n - (CF2) x-CF3;m cero, 1 ó 2;m cero, 1, 2, 3, 4, 5 ó 6;x y p independientemente entre sí cero ó 1;R(2) hidrógeno, F, Cl, Br, I, CN, alquilo de 1, 2, 3 ó 4 átomos de carbono, metoxi, cicloalquilo de 3, 4, 5, 6, 7 u 8 átomos de carbono, R(4) y R(5) independientemente entre sí hidrógeno, alquilo de 1, 2, 3 ó 4 átomos de carbono;R(6), R(7), R(8) y R(9)-independientemente entre sí hidrógeno, alquilo de 1, 2, 3 ó 4 átomos de carbono; alcoxi de 1, 2, 3 ó 4 átomos de carbono, F, Cl, Br, I, CN, NR(12)R(13), - Oq - (CH2)r- (CF2)s-CF3 o -(SOw)t - (CH2)u(CF2) v-CF3;R(12) y R(13) independientemente entre sí hidrógeno, alquilo de 1, 2, 3 ó 4 átomos de carbono;w cero, 1 ó 2;r y ucero, 1, 2, 3, 4, 5 ó 6;q, s, t y vindependientemente entre sí cero ó 1;o R(6) y R(7) o R(7) y R(8) o R(8) y R(9) junto con el anillo de fenilo que los lleva un sistema naftaleno;A -S-, -SO- o - SO2-y las sales farmacéuticamente adecuadas de las mismas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10204989A DE10204989A1 (de) | 2002-02-07 | 2002-02-07 | Dihydro-thia-phenanthren-carbonyl-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5601008A2 true CO5601008A2 (es) | 2006-01-31 |
Family
ID=27618378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO04076743A CO5601008A2 (es) | 2002-02-07 | 2004-08-06 | Dihidrotiafenantrencarbonilguanidinas, proceso para su preparacion, su uso como medicamento o auxiliar de diagnostico y medicamentos que las comprenden |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1474414B1 (es) |
| JP (1) | JP4410564B2 (es) |
| KR (1) | KR20040096555A (es) |
| CN (1) | CN1319963C (es) |
| AR (1) | AR038393A1 (es) |
| AT (1) | ATE380805T1 (es) |
| AU (1) | AU2003208337A1 (es) |
| BR (1) | BR0307495A (es) |
| CA (1) | CA2475093A1 (es) |
| CO (1) | CO5601008A2 (es) |
| DE (2) | DE10204989A1 (es) |
| HK (1) | HK1073656A1 (es) |
| HR (1) | HRP20040721A2 (es) |
| HU (1) | HUP0402595A2 (es) |
| MA (1) | MA27171A1 (es) |
| MX (1) | MXPA04007476A (es) |
| NO (1) | NO20043717L (es) |
| NZ (1) | NZ534536A (es) |
| PE (1) | PE20030963A1 (es) |
| PL (1) | PL370271A1 (es) |
| RS (1) | RS69204A (es) |
| RU (1) | RU2306311C2 (es) |
| TW (1) | TWI268927B (es) |
| WO (1) | WO2003066620A1 (es) |
| ZA (1) | ZA200406015B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200614995A (en) * | 2004-11-10 | 2006-05-16 | Nicholas Piramal India Ltd | Tricyclic guanidine derivatives as sodium-proton exchange inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60262887A (ja) * | 1984-06-11 | 1985-12-26 | Mitsubishi Chem Ind Ltd | 液晶組成物 |
| GB8505756D0 (en) * | 1985-03-06 | 1985-04-11 | Erba Farmitalia | Tricyclic dibenzo condensed derivatives |
| US4948806A (en) * | 1988-03-30 | 1990-08-14 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic compounds and compositions |
| DE19601303A1 (de) * | 1996-01-16 | 1997-07-17 | Boehringer Ingelheim Kg | Neuartige Benzoylguanidin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung bei der Herstellung von Arzneimitteln |
| CA2370607A1 (en) * | 1999-04-23 | 2000-11-02 | Bristol-Myers Squibb Company | Bicyclic acyl guanidine sodium/proton exchange inhibitors and method |
| DE10001879A1 (de) * | 2000-01-19 | 2001-07-19 | Aventis Pharma Gmbh | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
2002
- 2002-02-07 DE DE10204989A patent/DE10204989A1/de not_active Withdrawn
-
2003
- 2003-01-23 KR KR10-2004-7012241A patent/KR20040096555A/ko not_active Application Discontinuation
- 2003-01-23 RS YU69204A patent/RS69204A/sr unknown
- 2003-01-23 AT AT03706373T patent/ATE380805T1/de not_active IP Right Cessation
- 2003-01-23 EP EP03706373A patent/EP1474414B1/de not_active Expired - Lifetime
- 2003-01-23 WO PCT/EP2003/000653 patent/WO2003066620A1/de active IP Right Grant
- 2003-01-23 DE DE50308787T patent/DE50308787D1/de not_active Expired - Lifetime
- 2003-01-23 MX MXPA04007476A patent/MXPA04007476A/es active IP Right Grant
- 2003-01-23 BR BR0307495-1A patent/BR0307495A/pt not_active IP Right Cessation
- 2003-01-23 HU HU0402595A patent/HUP0402595A2/hu unknown
- 2003-01-23 RU RU2004126854/04A patent/RU2306311C2/ru not_active IP Right Cessation
- 2003-01-23 PL PL03370271A patent/PL370271A1/xx not_active Application Discontinuation
- 2003-01-23 AU AU2003208337A patent/AU2003208337A1/en not_active Abandoned
- 2003-01-23 CN CNB038035502A patent/CN1319963C/zh not_active Expired - Fee Related
- 2003-01-23 JP JP2003565993A patent/JP4410564B2/ja not_active Expired - Fee Related
- 2003-01-23 CA CA002475093A patent/CA2475093A1/en not_active Abandoned
- 2003-01-23 NZ NZ534536A patent/NZ534536A/en unknown
- 2003-01-30 TW TW092102087A patent/TWI268927B/zh not_active IP Right Cessation
- 2003-02-05 AR ARP030100363A patent/AR038393A1/es unknown
- 2003-02-05 PE PE2003000136A patent/PE20030963A1/es not_active Application Discontinuation
-
2004
- 2004-07-27 MA MA27802A patent/MA27171A1/fr unknown
- 2004-07-28 ZA ZA200406015A patent/ZA200406015B/en unknown
- 2004-08-06 HR HR20040721A patent/HRP20040721A2/hr not_active Application Discontinuation
- 2004-08-06 CO CO04076743A patent/CO5601008A2/es not_active Application Discontinuation
- 2004-09-06 NO NO20043717A patent/NO20043717L/no not_active Application Discontinuation
-
2005
- 2005-07-21 HK HK05106161A patent/HK1073656A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL370271A1 (en) | 2005-05-16 |
| DE10204989A1 (de) | 2003-08-21 |
| NZ534536A (en) | 2006-02-24 |
| HK1073656A1 (en) | 2005-10-14 |
| JP2005517015A (ja) | 2005-06-09 |
| HUP0402595A2 (hu) | 2005-04-28 |
| JP4410564B2 (ja) | 2010-02-03 |
| CN1319963C (zh) | 2007-06-06 |
| PE20030963A1 (es) | 2004-01-12 |
| RS69204A (en) | 2006-12-15 |
| KR20040096555A (ko) | 2004-11-16 |
| HRP20040721A2 (en) | 2005-06-30 |
| RU2004126854A (ru) | 2006-01-27 |
| MA27171A1 (fr) | 2005-01-03 |
| TWI268927B (en) | 2006-12-21 |
| AR038393A1 (es) | 2005-01-12 |
| AU2003208337A1 (en) | 2003-09-02 |
| DE50308787D1 (de) | 2008-01-24 |
| EP1474414B1 (de) | 2007-12-12 |
| TW200404792A (en) | 2004-04-01 |
| CA2475093A1 (en) | 2003-08-14 |
| EP1474414A1 (de) | 2004-11-10 |
| CN1630649A (zh) | 2005-06-22 |
| NO20043717L (no) | 2004-11-03 |
| ATE380805T1 (de) | 2007-12-15 |
| RU2306311C2 (ru) | 2007-09-20 |
| WO2003066620A1 (de) | 2003-08-14 |
| ZA200406015B (en) | 2005-11-14 |
| BR0307495A (pt) | 2004-12-28 |
| MXPA04007476A (es) | 2004-11-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |