CL2004000664A1 - Compuestos derivados de acido 2-(trifluorometil)-2h-(cromeno o quinolina-3-arboxilico; composicion farmaceutica, utiles para el tratamiento y la prevencion de afecciones mediadas por ciclooxigenasa-2 (cox-2) tales como la inflamacion. - Google Patents

Compuestos derivados de acido 2-(trifluorometil)-2h-(cromeno o quinolina-3-arboxilico; composicion farmaceutica, utiles para el tratamiento y la prevencion de afecciones mediadas por ciclooxigenasa-2 (cox-2) tales como la inflamacion.

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Publication number
CL2004000664A1
CL2004000664A1 CL200400664A CL2004000664A CL2004000664A1 CL 2004000664 A1 CL2004000664 A1 CL 2004000664A1 CL 200400664 A CL200400664 A CL 200400664A CL 2004000664 A CL2004000664 A CL 2004000664A CL 2004000664 A1 CL2004000664 A1 CL 2004000664A1
Authority
CL
Chile
Prior art keywords
cyclloxygenase
arboxilico
quinolina
trifluorometil
inflamm
Prior art date
Application number
CL200400664A
Other languages
English (en)
Inventor
W Aston David L Brown Jef Karl
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of CL2004000664A1 publication Critical patent/CL2004000664A1/es

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CL200400664A 2003-03-31 2004-03-29 Compuestos derivados de acido 2-(trifluorometil)-2h-(cromeno o quinolina-3-arboxilico; composicion farmaceutica, utiles para el tratamiento y la prevencion de afecciones mediadas por ciclooxigenasa-2 (cox-2) tales como la inflamacion. CL2004000664A1 (es)

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US6034256A (en) * 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation
WO2006011052A1 (en) * 2004-07-23 2006-02-02 Pharmacia & Upjohn Company Llc Method for the racemization of 2-trifluoro-2h-chromene-3-carboxylic acids
JP2008507501A (ja) * 2004-07-23 2008-03-13 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー ２−トリフルオロメチル−２ｈ−クロメン−３−カルボン酸誘導体の光ラセミ化
BRPI0512251A (pt) * 2004-07-23 2008-02-19 Pharmacia & Upjohn Co Llc método enantioseletivo para separação de derivados do ácido 2-trifluormetil-2h-cromeno-3-carboxìlico substituìdo
WO2006040676A1 (en) * 2004-10-12 2006-04-20 Pharmacia & Upjohn Company Llc Nitrosated benzopyran compounds as novel cyclooxygenase-2 selective inhibitors
GB0608825D0 (en) * 2006-05-04 2006-06-14 Glaxo Group Ltd Compounds
CN102757417B (zh) * 2012-06-18 2014-09-24 中国科学院广州生物医药与健康研究院 氘代苯并吡喃类化合物及其应用
JP6061373B2 (ja) * 2012-07-24 2017-01-18 国立研究開発法人産業技術総合研究所 ２−ヒドロキシベンズアルデヒド化合物、これを含有するコラーゲン細胞外分泌阻害剤及び医薬品組成物
CN103012350B (zh) * 2012-12-07 2015-02-04 中国科学院广州生物医药与健康研究院 苯并吡喃类手性化合物的合成方法
AU2015206528B2 (en) * 2014-01-14 2019-04-18 Euclises Pharmaceuticals, Inc. NO-releasing nitrooxy-chromene conjugates
AU2015240774B2 (en) * 2014-04-01 2019-08-15 Howard Hughes Medical Institute Azetidine-substituted fluorescent compounds
EP3310822B1 (en) * 2015-06-19 2023-10-11 SABIC Global Technologies B.V. Procatalyst for polymerization of olefins comprising an aminobenzoate internal donor and a 1,3-diether internal donor in a specific ratio
GB2543550A (en) 2015-10-21 2017-04-26 Hox Therapeutics Ltd Peptides
US20220169639A1 (en) * 2018-12-14 2022-06-02 Hoffmann-La Roche Inc. N-containing chromen-4-one derivatives for the treatment and prophylaxis of hepatitis b virus infection

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US6034256A (en) * 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation

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BRPI0408389A (pt) 2006-03-01
JP2006522091A (ja) 2006-09-28
UY28247A1 (es) 2004-11-08
WO2004087687A1 (en) 2004-10-14
TW200504045A (en) 2005-02-01
NL1025844C2 (nl) 2005-03-01
AR043951A1 (es) 2005-08-17
US20050148627A1 (en) 2005-07-07
NL1025844A1 (nl) 2004-10-01
CA2519291A1 (en) 2004-10-14
PE20050393A1 (es) 2005-05-30
PA8599301A1 (es) 2004-12-16
EP1631562A1 (en) 2006-03-08

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