RS59498B1 - Nova kriptoficinska jedinjenja i konjugati, njihova priprema i njihova terapeutska primena - Google Patents

Nova kriptoficinska jedinjenja i konjugati, njihova priprema i njihova terapeutska primena

Info

Publication number
RS59498B1
RS59498B1 RS20191429A RSP20191429A RS59498B1 RS 59498 B1 RS59498 B1 RS 59498B1 RS 20191429 A RS20191429 A RS 20191429A RS P20191429 A RSP20191429 A RS P20191429A RS 59498 B1 RS59498 B1 RS 59498B1
Authority
RS
Serbia
Prior art keywords
support
pillow
head
core
neck support
Prior art date
Application number
RS20191429A
Other languages
English (en)
Serbian (sr)
Inventor
Antony Bigot
Hervé Bouchard
Marie-Priscille Brun
François Clerc
Jidong Zhang
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of RS59498B1 publication Critical patent/RS59498B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Bedding Items (AREA)
RS20191429A 2015-11-05 2016-11-03 Nova kriptoficinska jedinjenja i konjugati, njihova priprema i njihova terapeutska primena RS59498B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15306751 2015-11-05
EP16791017.3A EP3371179B1 (en) 2015-11-05 2016-11-03 Novel cryptophycin compounds and conjugates, their preparation and their therapeutic use
PCT/EP2016/076603 WO2017076998A1 (en) 2015-11-05 2016-11-03 Novel cryptophycin compounds and conjugates, their preparation and their therapeutic use

Publications (1)

Publication Number Publication Date
RS59498B1 true RS59498B1 (sr) 2019-12-31

Family

ID=54476881

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20191429A RS59498B1 (sr) 2015-11-05 2016-11-03 Nova kriptoficinska jedinjenja i konjugati, njihova priprema i njihova terapeutska primena

Country Status (35)

Country Link
US (2) US10941139B2 (enExample)
EP (1) EP3371179B1 (enExample)
JP (1) JP6929292B2 (enExample)
KR (1) KR102822076B1 (enExample)
CN (1) CN108349960B (enExample)
AR (1) AR106604A1 (enExample)
AU (1) AU2016347724B2 (enExample)
CA (1) CA3003085A1 (enExample)
CL (1) CL2018001210A1 (enExample)
CO (1) CO2018004581A2 (enExample)
CR (1) CR20180256A (enExample)
CY (1) CY1122441T1 (enExample)
DK (1) DK3371179T3 (enExample)
EA (1) EA035625B1 (enExample)
EC (1) ECSP18034035A (enExample)
ES (1) ES2755101T3 (enExample)
HK (1) HK1256754B (enExample)
HR (1) HRP20191729T1 (enExample)
HU (1) HUE046033T2 (enExample)
IL (1) IL259067B (enExample)
LT (1) LT3371179T (enExample)
MA (1) MA43160B1 (enExample)
MX (1) MX374535B (enExample)
MY (1) MY189448A (enExample)
PH (1) PH12018500852B1 (enExample)
PL (1) PL3371179T3 (enExample)
PT (1) PT3371179T (enExample)
RS (1) RS59498B1 (enExample)
SG (1) SG11201803181SA (enExample)
SI (1) SI3371179T1 (enExample)
TN (1) TN2018000131A1 (enExample)
TW (1) TWI714661B (enExample)
UY (1) UY36979A (enExample)
WO (1) WO2017076998A1 (enExample)
ZA (1) ZA201802322B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI714661B (zh) 2015-11-05 2021-01-01 法商賽諾菲公司 新穎念珠藻素化合物及接合物、其製備與其治療用途
CN107043380A (zh) 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途
TN2019000303A1 (en) 2017-05-10 2021-05-07 Sanofi Sa Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation
CN108107103B (zh) * 2017-12-14 2020-10-16 华中师范大学 谷氨酸受体的质谱探针及其在脑组织中的空间分布规律检测方法
ES2988904T3 (es) 2019-03-07 2024-11-22 Nobo Medicine Inc Inhibidores de caspasa y métodos de utilización de los mismos
JP2022549971A (ja) 2019-09-30 2022-11-29 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン クリプトフィシン抗がん剤の生体触媒合成
EP4046996A1 (en) 2021-02-19 2022-08-24 Universität Bielefeld Cryptophycin compounds and conjugates thereof
CN118742328A (zh) 2022-02-22 2024-10-01 阿拉里斯生物技术股份公司 包含两个或更多个有效载荷的肽接头
EP4495105A1 (en) 2023-07-17 2025-01-22 Basf Se 3-(4-hydroxybut-2-ynoxy)propanoic acid ester, amide and nitrile derivatives as corrosion protection agents
EP4495108A1 (en) 2023-07-17 2025-01-22 Basf Se 3-[2-(2-oxo-1,3-dioxolan-4-ylidene)ethoxy]propanoic acid derivatives as precursors of monomers in polymerisations
WO2025082990A1 (en) 2023-10-15 2025-04-24 Araris Biotech Ag Antibody-drug conjugates using two different types of topoisomerase i inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0735819B1 (en) * 1993-12-21 2001-07-11 University Of Hawaii Cryptophycins
US20020128185A1 (en) * 1998-02-25 2002-09-12 Chuan Shih Pharmaceutical compounds
US7230101B1 (en) 2002-08-28 2007-06-12 Gpc Biotech, Inc. Synthesis of methotrexate-containing heterodimeric molecules
US20050175619A1 (en) 2004-02-05 2005-08-11 Robert Duffy Methods of producing antibody conjugates
EP2010475A2 (en) 2006-04-27 2009-01-07 Intezyne Technologies Incorporated Heterofunctional poly(ethylene glycol) containing acid-labile amino protecting groups and uses thereof
CN101622276B (zh) 2006-07-18 2015-04-22 赛诺菲-安万特 用于治疗癌症的抗epha2的拮抗抗体
FR2947269B1 (fr) * 2009-06-29 2013-01-18 Sanofi Aventis Nouveaux composes anticancereux
TW201116297A (en) 2009-10-02 2011-05-16 Sanofi Aventis Antibodies that specifically bind to the EphA2 receptor
TWI714661B (zh) * 2015-11-05 2021-01-01 法商賽諾菲公司 新穎念珠藻素化合物及接合物、其製備與其治療用途

Also Published As

Publication number Publication date
US10941139B2 (en) 2021-03-09
US20210163458A1 (en) 2021-06-03
EA035625B1 (ru) 2020-07-17
DK3371179T3 (da) 2019-11-11
IL259067A (en) 2018-06-28
SG11201803181SA (en) 2018-05-30
KR20180073678A (ko) 2018-07-02
CN108349960B (zh) 2022-05-27
CL2018001210A1 (es) 2018-08-17
EP3371179A1 (en) 2018-09-12
UY36979A (es) 2017-06-30
TN2018000131A1 (en) 2019-10-04
CO2018004581A2 (es) 2018-07-19
TW201730164A (zh) 2017-09-01
IL259067B (en) 2021-07-29
ZA201802322B (en) 2019-01-30
MX2018005379A (es) 2018-09-05
PH12018500852A1 (en) 2018-10-29
JP2018535255A (ja) 2018-11-29
PH12018500852B1 (en) 2021-08-11
TWI714661B (zh) 2021-01-01
LT3371179T (lt) 2019-11-11
BR112018008490A2 (pt) 2019-02-12
SI3371179T1 (sl) 2019-11-29
EA201890898A1 (ru) 2018-10-31
ECSP18034035A (es) 2018-05-31
AR106604A1 (es) 2018-01-31
MX374535B (es) 2025-03-06
AU2016347724A1 (en) 2018-05-10
HK1256754B (en) 2020-06-05
EP3371179B1 (en) 2019-08-07
CY1122441T1 (el) 2021-01-27
MA43160B1 (fr) 2019-12-31
NZ741734A (en) 2023-10-27
PL3371179T3 (pl) 2020-02-28
CA3003085A1 (en) 2017-05-11
HUE046033T2 (hu) 2020-01-28
KR102822076B1 (ko) 2025-06-18
HRP20191729T1 (hr) 2019-12-13
US20190382391A1 (en) 2019-12-19
CN108349960A (zh) 2018-07-31
JP6929292B2 (ja) 2021-09-01
WO2017076998A1 (en) 2017-05-11
AU2016347724B2 (en) 2021-04-01
CR20180256A (es) 2018-08-13
PT3371179T (pt) 2019-11-18
MY189448A (en) 2022-02-14
ES2755101T3 (es) 2020-04-21

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