RS51250B - Modifikovani hekson protein adenovirusa i njegova upotreba - Google Patents
Modifikovani hekson protein adenovirusa i njegova upotrebaInfo
- Publication number
- RS51250B RS51250B RSP-2010/0181A RSP20100181A RS51250B RS 51250 B RS51250 B RS 51250B RS P20100181 A RSP20100181 A RS P20100181A RS 51250 B RS51250 B RS 51250B
- Authority
- RS
- Serbia
- Prior art keywords
- hypervariable region
- hexone
- hexon protein
- modified adenovirus
- adenovirus hexon
- Prior art date
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- C07K2319/00—Fusion polypeptide
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10041—Use of virus, viral particle or viral elements as a vector
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- C12N2710/10011—Adenoviridae
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- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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- C12N2740/00—Reverse transcribing RNA viruses
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- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2810/00—Vectors comprising a targeting moiety
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- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
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- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
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- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
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Abstract
Adenovirus koji ima kapsid koji obuhvata modifikovani adenovirusni protein hekson, pomenuti modifikovani adenovirusni protein hekson obuhvata deleciju bar u hipervarijabilnom regionu adenovirusnog proteina heksona koji je odabran od hipervarijabilnog regiona 1 i hipervarijabilnog regiona 4 i egzogenu amino kiselinsku sekvencu koja obuhvata imunogenu amino kiselinsku sekvencu koja je ubačena u pomenuti hipervarijabilni region 1 i/ili pomenuti hipervarijabilni region 4, pod uslovom da pomenuta egzogena amino kiselinska sekvenca je drugačija od adenovirusne sekvence.Prijava sadrži još 21 patentni zahtev.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79607806P | 2006-04-28 | 2006-04-28 | |
PCT/US2007/010347 WO2008010864A2 (en) | 2006-04-28 | 2007-04-27 | Modified adenovirus hexon protein and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
RS51250B true RS51250B (sr) | 2010-12-31 |
Family
ID=38957245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RSP-2010/0181A RS51250B (sr) | 2006-04-28 | 2007-04-27 | Modifikovani hekson protein adenovirusa i njegova upotreba |
Country Status (15)
Country | Link |
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US (3) | US20090074810A1 (sr) |
EP (1) | EP2012822B1 (sr) |
JP (1) | JP5889514B2 (sr) |
CN (1) | CN101437538A (sr) |
AT (1) | ATE455558T1 (sr) |
CY (1) | CY1110002T1 (sr) |
DE (1) | DE602007004470D1 (sr) |
DK (1) | DK2012822T3 (sr) |
ES (1) | ES2341501T3 (sr) |
HR (1) | HRP20100228T1 (sr) |
PL (1) | PL2012822T3 (sr) |
PT (1) | PT2012822E (sr) |
RS (1) | RS51250B (sr) |
SI (1) | SI2012822T1 (sr) |
WO (1) | WO2008010864A2 (sr) |
Families Citing this family (46)
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JP2009533350A (ja) | 2006-04-07 | 2009-09-17 | キメロス, インコーポレイテッド | B細胞悪性疾患を処置するための組成物および方法 |
EP2220217A2 (en) * | 2007-11-28 | 2010-08-25 | The Trustees of the University of Pennsylvania | Simian subfamily c adenoviruses sadv-40, -31, and-34 and uses thereof |
DK2220242T3 (en) | 2007-11-28 | 2017-03-27 | Univ Pennsylvania | ABE-ADENOVIRA OF GROUP B, SADV-28,27, -29, -32, -33 AND -35 AND APPLICATIONS THEREOF |
CN101883858B (zh) * | 2007-11-28 | 2015-07-22 | 宾夕法尼亚大学托管会 | 猿猴亚家族E腺病毒SAdV-39、-25.2、-26、-30、-37和-38及其应用 |
JP5661476B2 (ja) | 2008-03-04 | 2015-01-28 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | サルアデノウイルスSAdV−36、−42.1、−42.2および−44ならびにそれらの用途 |
WO2010051367A1 (en) | 2008-10-31 | 2010-05-06 | The Trustees Of The University Of Pennsylvania | Simian adenoviruses sadv-43, -45,-48,-49, and -50 and uses thereof |
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JP5785607B2 (ja) * | 2010-04-14 | 2015-09-30 | モガム バイオテクノロジー リサーチ インスティチュート | サルアデノウイルス血清型19から単離されたヘキソン、その超可変領域、およびそれらを用いるキメラアデノウイルス |
EP2643465B1 (en) | 2010-11-23 | 2016-05-11 | The Trustees Of The University Of Pennsylvania | Subfamily e simian adenovirus a1321 and uses thereof |
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CN103242433B (zh) * | 2012-02-14 | 2016-12-14 | 中国医学科学院病原生物学研究所 | 一种腺病毒非结构蛋白免疫原、其抗体及应用 |
SG10201609511XA (en) | 2012-05-18 | 2016-12-29 | Univ Pennsylvania | Subfamily e simian adenoviruses a1302, a1320, a1331 and a1337 and uses thereof |
US9222142B2 (en) * | 2013-01-15 | 2015-12-29 | The Regents Of The University Of California | Adenoviruses and their use |
EP2971008B1 (en) | 2013-03-14 | 2018-07-25 | Salk Institute for Biological Studies | Oncolytic adenovirus compositions |
BR112016008806A2 (pt) | 2013-11-01 | 2017-10-03 | Pfizer | Vetores para expressão de antígenos associados à próstata |
CN103865923B (zh) * | 2014-01-28 | 2017-04-26 | 中国人民解放军第三0二医院 | 流感病毒为载体的HAdV嵌合疫苗的制备及其应用 |
EP2940128A1 (en) | 2014-04-30 | 2015-11-04 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Adenovirus comprising an albumin-binding moiety |
WO2015191508A1 (en) | 2014-06-09 | 2015-12-17 | Voyager Therapeutics, Inc. | Chimeric capsids |
BR112017009497A2 (pt) | 2014-11-05 | 2018-02-06 | Voyager Therapeutics, Inc. | polinucleotídeos de aadc para o tratamento da doença de parkinson |
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WO1998010087A1 (en) * | 1996-09-06 | 1998-03-12 | Trustees Of The University Of Pennsylvania | Chimpanzee adenovirus vectors |
US6211160B1 (en) * | 1996-09-06 | 2001-04-03 | The Trustees Of The University Of Pennsylvania | Method for tolerizing a mammalian patient to administration of gene therapy virus vectors |
JP2002523105A (ja) * | 1998-08-27 | 2002-07-30 | アバンテイス・フアルマ・エス・アー | 異種遺伝子の運搬用の標的化アデノウイルスベクター |
US6955808B2 (en) * | 1999-09-24 | 2005-10-18 | Uab Research Foundation | Capsid-modified recombinant adenovirus and methods of use |
MXPA04004876A (es) * | 2001-11-21 | 2004-07-30 | Univ Pennsylvania | Secuencias de acido nucleico y de aminoacido de adenovirus de simio, vectores que contienen los mismos y metodos de uso. |
EP1388541A1 (en) * | 2002-08-09 | 2004-02-11 | Centre National De La Recherche Scientifique (Cnrs) | Pyrrolopyrazines as kinase inhibitors |
US7291498B2 (en) * | 2003-06-20 | 2007-11-06 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
ES2478625T3 (es) * | 2003-06-20 | 2014-07-22 | The Trustees Of The University Of Pennsylvania | Método de generación de adenovirus quiméricos y usos de tales adenovirus quiméricos |
US7144712B2 (en) * | 2003-07-30 | 2006-12-05 | Vaccine Research Institute Of San Diego | Human hepatitis B virus core proteins as vaccine platforms and methods of use thereof |
FR2860004A1 (fr) * | 2003-09-18 | 2005-03-25 | Roussy Inst Gustave | Nouveau vecteur adenoviral pour l'infection de cellules deficientes ou depourvues en recepteurs car |
-
2007
- 2007-04-27 PT PT07835738T patent/PT2012822E/pt unknown
- 2007-04-27 DK DK07835738.1T patent/DK2012822T3/da active
- 2007-04-27 DE DE602007004470T patent/DE602007004470D1/de active Active
- 2007-04-27 CN CNA2007800150045A patent/CN101437538A/zh active Pending
- 2007-04-27 US US12/226,593 patent/US20090074810A1/en not_active Abandoned
- 2007-04-27 PL PL07835738T patent/PL2012822T3/pl unknown
- 2007-04-27 WO PCT/US2007/010347 patent/WO2008010864A2/en active Application Filing
- 2007-04-27 JP JP2009507838A patent/JP5889514B2/ja not_active Expired - Fee Related
- 2007-04-27 AT AT07835738T patent/ATE455558T1/de active
- 2007-04-27 SI SI200730215T patent/SI2012822T1/sl unknown
- 2007-04-27 ES ES07835738T patent/ES2341501T3/es active Active
- 2007-04-27 RS RSP-2010/0181A patent/RS51250B/sr unknown
- 2007-04-27 EP EP07835738A patent/EP2012822B1/en active Active
-
2010
- 2010-04-16 CY CY20101100344T patent/CY1110002T1/el unknown
- 2010-04-19 HR HR20100228T patent/HRP20100228T1/hr unknown
-
2015
- 2015-05-22 US US14/719,893 patent/US20160102295A1/en not_active Abandoned
-
2016
- 2016-12-20 US US15/385,195 patent/US20170096646A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DK2012822T3 (da) | 2010-05-25 |
PL2012822T3 (pl) | 2010-06-30 |
US20170096646A1 (en) | 2017-04-06 |
WO2008010864A3 (en) | 2008-05-02 |
US20090074810A1 (en) | 2009-03-19 |
PT2012822E (pt) | 2010-04-27 |
US20160102295A1 (en) | 2016-04-14 |
HRP20100228T1 (hr) | 2010-07-31 |
WO2008010864A2 (en) | 2008-01-24 |
EP2012822B1 (en) | 2010-01-20 |
ES2341501T3 (es) | 2010-06-21 |
DE602007004470D1 (de) | 2010-03-11 |
EP2012822A2 (en) | 2009-01-14 |
JP2009535032A (ja) | 2009-10-01 |
JP5889514B2 (ja) | 2016-03-22 |
ATE455558T1 (de) | 2010-02-15 |
SI2012822T1 (sl) | 2010-06-30 |
CN101437538A (zh) | 2009-05-20 |
CY1110002T1 (el) | 2015-01-14 |
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