RS50946B - Karbamatna jedinjenja za upotrebu u sprečavanju ili lečenju neuropatskog bola u veza sa klasterskim i migrenskim glavoboljama - Google Patents

Karbamatna jedinjenja za upotrebu u sprečavanju ili lečenju neuropatskog bola u veza sa klasterskim i migrenskim glavoboljama

Info

Publication number
RS50946B
RS50946B YUP-45/04A YUP4504A RS50946B RS 50946 B RS50946 B RS 50946B YU P4504 A YUP4504 A YU P4504A RS 50946 B RS50946 B RS 50946B
Authority
RS
Serbia
Prior art keywords
pain
cluster
preventing
migraine headache
phenyl
Prior art date
Application number
YUP-45/04A
Other languages
English (en)
Inventor
Boyu Zhao
Ellen C. Cood
Carlos R. Plata-Salaman
Original Assignee
Ortho-Mcneil Pharmaceutical Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil Pharmaceutical Inc. filed Critical Ortho-Mcneil Pharmaceutical Inc.
Publication of RS4504A publication Critical patent/RS4504A/sr
Publication of RS50946B publication Critical patent/RS50946B/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Upotreba u proizvodnji leka za sprečavanje ili lečenje neuropatskog bola i bola u vezi sa klasterskim i migrenskim glavoboljama, enantiomera formule (I) bez drugih enantiomera ili enantiomerne smeše u kojoj enantiomer formule (I) predominirau kojojfenil je supstituisan sa X, sa jednim do pet atoma halogena izabranih iz grupe koju čine fluor, hlor, brom i jod; iR1 i R2 su nezavisno izabrani iz grupe koju čine vodonik i C1-C4 alkil; gde C1-C4 alkil je opciono supstituisan sa fenilom, gde je fenil opciono supstituisan sa supstituentima nezavisno izabranim iz grupe koju čine halogen. C1-C4 alkil, C1-C4 alkoksi, amino, nitro i cijano.Prijava sadrži još 11 patentnih zahteva.
YUP-45/04A 2001-07-16 2002-07-11 Karbamatna jedinjenja za upotrebu u sprečavanju ili lečenju neuropatskog bola u veza sa klasterskim i migrenskim glavoboljama RS50946B (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30568701P 2001-07-16 2001-07-16
PCT/US2002/021787 WO2003007936A1 (en) 2001-07-16 2002-07-11 Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
US10/192,973 US20030069306A1 (en) 2001-07-16 2002-07-11 Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain

Publications (2)

Publication Number Publication Date
RS4504A RS4504A (en) 2006-12-15
RS50946B true RS50946B (sr) 2010-08-31

Family

ID=26888550

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-45/04A RS50946B (sr) 2001-07-16 2002-07-11 Karbamatna jedinjenja za upotrebu u sprečavanju ili lečenju neuropatskog bola u veza sa klasterskim i migrenskim glavoboljama

Country Status (23)

Country Link
US (3) US20030069306A1 (sr)
EP (1) EP1406606B1 (sr)
JP (1) JP4362368B2 (sr)
KR (1) KR100995936B1 (sr)
CN (2) CN1592617A (sr)
AU (1) AU2002354909B2 (sr)
BR (1) BR0211240A (sr)
CA (1) CA2454047C (sr)
CY (1) CY1106038T1 (sr)
DE (1) DE60217493T2 (sr)
DK (1) DK1406606T3 (sr)
ES (1) ES2278035T3 (sr)
HK (1) HK1063288A1 (sr)
HU (1) HUP0401110A3 (sr)
IL (1) IL159846A0 (sr)
MX (1) MXPA04000555A (sr)
NO (1) NO20040177L (sr)
NZ (1) NZ549751A (sr)
PL (1) PL368112A1 (sr)
PT (1) PT1406606E (sr)
RS (1) RS50946B (sr)
RU (1) RU2299729C2 (sr)
WO (1) WO2003007936A1 (sr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0523550D0 (en) 2005-11-18 2005-12-28 Hunter Fleming Ltd Therapeutic uses of steroidal compounds
KR102489052B1 (ko) * 2016-05-19 2023-01-16 에스케이바이오팜 주식회사 섬유근육통 또는 섬유근육통의 연관된 기능적 증후군을 예방 또는 치료하기 위한 카바메이트 화합물의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
BR0112713A (pt) * 2000-07-21 2003-07-22 Ortho Mcneil Pharm Inc "compostos de carbamato para uso na prevenção ou tratamento de dor neuropática e dor associada a cefaléia em cacho e hemicrânia

Also Published As

Publication number Publication date
WO2003007936A1 (en) 2003-01-30
EP1406606A1 (en) 2004-04-14
HUP0401110A2 (hu) 2004-09-28
US20060293383A1 (en) 2006-12-28
WO2003007936A8 (en) 2004-10-14
PL368112A1 (en) 2005-03-21
NO20040177L (no) 2004-03-16
HK1063288A1 (en) 2004-12-24
DE60217493T2 (de) 2007-11-15
HUP0401110A3 (en) 2012-09-28
CA2454047C (en) 2011-06-21
CN1592617A (zh) 2005-03-09
JP2004536856A (ja) 2004-12-09
AU2002354909B2 (en) 2006-10-05
PT1406606E (pt) 2007-03-30
JP4362368B2 (ja) 2009-11-11
KR100995936B1 (ko) 2010-11-22
ES2278035T3 (es) 2007-08-01
BR0211240A (pt) 2004-07-27
US20050009905A1 (en) 2005-01-13
NZ549751A (en) 2008-04-30
DK1406606T3 (da) 2007-03-05
RS4504A (en) 2006-12-15
EP1406606B1 (en) 2007-01-10
IL159846A0 (en) 2004-06-20
CA2454047A1 (en) 2003-01-30
CY1106038T1 (el) 2011-04-06
MXPA04000555A (es) 2005-06-20
RU2299729C2 (ru) 2007-05-27
RU2004100965A (ru) 2005-02-20
DE60217493D1 (de) 2007-02-22
CN101669933A (zh) 2010-03-17
US20030069306A1 (en) 2003-04-10
KR20040016993A (ko) 2004-02-25

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