RS20080388A - Lečenje malignih bolesti - Google Patents

Lečenje malignih bolesti

Info

Publication number
RS20080388A
RS20080388A RSP-2008/0388A RSP20080388A RS20080388A RS 20080388 A RS20080388 A RS 20080388A RS P20080388 A RSP20080388 A RS P20080388A RS 20080388 A RS20080388 A RS 20080388A
Authority
RS
Serbia
Prior art keywords
oxaliplatin
liposome
cancer
dose
drug
Prior art date
Application number
RSP-2008/0388A
Other languages
English (en)
Serbian (sr)
Inventor
Parthenios Boulikas
Original Assignee
Parthenios Boulikas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parthenios Boulikas filed Critical Parthenios Boulikas
Publication of RS20080388A publication Critical patent/RS20080388A/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RSP-2008/0388A 2006-03-03 2007-03-05 Lečenje malignih bolesti RS20080388A (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GR20060100144A GR20060100144A (el) 2006-03-03 2006-03-03 Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene
PCT/GR2007/000015 WO2007099377A2 (en) 2006-03-03 2007-03-05 Cancer treatments

Publications (1)

Publication Number Publication Date
RS20080388A true RS20080388A (sr) 2009-07-15

Family

ID=38325437

Family Applications (1)

Application Number Title Priority Date Filing Date
RSP-2008/0388A RS20080388A (sr) 2006-03-03 2007-03-05 Lečenje malignih bolesti

Country Status (17)

Country Link
US (1) US20090053302A1 (enExample)
EP (1) EP2001441A2 (enExample)
JP (1) JP2009528340A (enExample)
KR (1) KR20090023548A (enExample)
CN (1) CN101522172A (enExample)
AU (1) AU2007220263A1 (enExample)
BR (1) BRPI0707059A2 (enExample)
CA (1) CA2644566A1 (enExample)
EA (1) EA200801912A1 (enExample)
GR (1) GR20060100144A (enExample)
MA (1) MA30314B1 (enExample)
MX (1) MX2008011263A (enExample)
NO (1) NO20083927L (enExample)
RS (1) RS20080388A (enExample)
TN (1) TNSN08345A1 (enExample)
WO (1) WO2007099377A2 (enExample)
ZA (1) ZA200807934B (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9186322B2 (en) * 2002-08-02 2015-11-17 Insmed Incorporated Platinum aggregates and process for producing the same
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
KR20080094473A (ko) * 2007-04-20 2008-10-23 한국화학연구원 음이온성 지질나노입자 및 이의 제조방법
ES2465477T3 (es) * 2008-01-28 2014-06-05 Nanocarrier Co., Ltd. Composición farmacéutica y fármaco combinado
TWI468188B (zh) * 2008-01-30 2015-01-11 Univ Tokushima Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation
EP2259844A4 (en) * 2008-03-05 2012-02-01 Vicus Therapeutics Llc COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGICAL THERAPIES
EP2123258A1 (en) * 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes for drug delivery
WO2010138550A1 (en) * 2009-05-27 2010-12-02 Northeastern University Conjugated nanodelivery vehicles
AU2010296180B2 (en) * 2009-09-21 2016-05-05 Bio-Synectics, Inc Oxaliplatin nanoparticles and method for preparing same
JP5817053B2 (ja) * 2010-04-02 2015-11-18 国立大学法人 千葉大学 腫瘍特異性を有するリポソーム
CN102133176B (zh) * 2011-03-22 2012-09-05 济南宏瑞创博医药科技开发有限公司 一种奥沙利铂胶束制剂及其制备方法及应用
JP5378469B2 (ja) 2011-08-11 2013-12-25 学校法人 日本歯科大学 医療用薬剤
SG10201701063WA (en) * 2012-08-10 2017-04-27 Taiho Pharmaceutical Co Ltd Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same
MA37931A1 (fr) * 2012-08-13 2016-07-29 Teni Boulikas Procédés améliorés permettant de traiter un cancer avec une toxicité rénale réduite
KR20150044838A (ko) * 2012-08-13 2015-04-27 레귤론, 인코퍼레이티드. 리포플라틴을 이용한 암 치료방법
EP2892524B1 (en) 2012-09-04 2020-11-25 Eleison Pharmaceuticals, LLC Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin
EA023757B1 (ru) * 2012-12-24 2016-07-29 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы оксалиплатина
EP2968144A1 (en) * 2013-03-13 2016-01-20 Mallinckrodt LLC Liposome oxaliplatin compositions for cancer therapy
UA117581C2 (uk) * 2013-03-27 2018-08-27 Тайхо Фармасьютікал Ко., Лтд. Протипухлинний лікарський засіб, який включає низькодозований гідрохлориду іринотекану гідрат
CN103622912B (zh) * 2013-12-05 2016-02-24 常州金远药业制造有限公司 盐酸多柔比星-多西他赛或紫杉醇脂质体制剂及其制备方法
CA2976526A1 (en) * 2015-02-13 2016-08-18 Trendmed Co., Ltd. Compositions and methods of tumor treatment utilizing nanoparticles
WO2016141161A1 (en) 2015-03-03 2016-09-09 Cureport, Inc. Dual loaded liposomal pharmaceutical formulations
WO2016141167A1 (en) 2015-03-03 2016-09-09 Cureport, Inc. Combination liposomal pharmaceutical formulations
KR101687735B1 (ko) * 2015-09-18 2016-12-19 서울대학교 산학협력단 신규의 동결건조보조제 및 새로운 인지질 용해용 혼합용매를 이용한 리포좀 동결분체의 제조방법
WO2017192502A1 (en) * 2016-05-03 2017-11-09 The American University In Cairo Liposomal delivery systems for oxaliplatin and in dual drug delivery in combination with chemo-sensitizing and chemo-therapeutic agents
US10940112B2 (en) 2016-05-04 2021-03-09 L.E.A.F. Holdings Group Llc Targeted liposomal gemcitabine compositions and methods thereof
CN106074379B (zh) * 2016-07-11 2019-01-25 中国科学院上海药物研究所 聚乙二醇化奥沙利铂前药及其制备方法和用途
CN112656764B (zh) * 2020-12-28 2022-09-02 吉林大学 一种紫杉醇铂类共载靶向长循环脂质体及应用
CN114814023B (zh) * 2022-04-24 2024-07-30 江苏省中医院 脂质分子在作为胃癌化疗药耐药的预测性标志物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2046997C (en) * 1990-07-16 2000-12-12 Hiroshi Kikuchi Liposomal products
US6060080A (en) * 1990-07-16 2000-05-09 Daiichi Pharmaceutical Co., Ltd. Liposomal products
US6511676B1 (en) * 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
CN1254234C (zh) * 2000-06-09 2006-05-03 莱古伦公司 质粒dna(lipogenestm)和含细胞核定位信号/促融合肽缀合物的治疗剂包封到定向脂质体复合体中
CA2383259A1 (en) * 2002-04-23 2003-10-23 Celator Technologies Inc. Synergistic compositions
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
JP3415131B1 (ja) * 2002-06-03 2003-06-09 メビオファーム株式会社 リポソーム製剤
EP1545459A4 (en) * 2002-08-02 2007-08-22 Transave Inc PLATINUM AGGREGATES, AND METHOD FOR MANUFACTURING THE SAME
AU2004235781A1 (en) * 2003-05-02 2004-11-18 Aronex Pharmaceuticals, Inc. Lipid platinum complexes and methods of use thereof
WO2005000266A2 (en) * 2003-05-22 2005-01-06 Neopharm, Inc. Liposomal formulations comprising a combination of two or more active agents

Also Published As

Publication number Publication date
MA30314B1 (fr) 2009-04-01
MX2008011263A (es) 2008-12-12
ZA200807934B (en) 2009-11-25
BRPI0707059A2 (pt) 2011-04-19
AU2007220263A1 (en) 2007-09-07
EA200801912A1 (ru) 2009-02-27
CA2644566A1 (en) 2007-09-07
JP2009528340A (ja) 2009-08-06
WO2007099377A2 (en) 2007-09-07
GR20060100144A (el) 2007-10-17
EP2001441A2 (en) 2008-12-17
TNSN08345A1 (en) 2009-12-29
CN101522172A (zh) 2009-09-02
US20090053302A1 (en) 2009-02-26
KR20090023548A (ko) 2009-03-05
WO2007099377A3 (en) 2008-04-17
NO20083927L (no) 2008-09-15

Similar Documents

Publication Publication Date Title
RS20080388A (sr) Lečenje malignih bolesti
JP7555630B2 (ja) カロテノイド組成物およびその使用
Pillai Nanotechnology toward treating cancer: A comprehensive review
JP5981214B2 (ja) リンパ腫の治療のための組成物および方法
JP5438317B2 (ja) 新規リポソーム組成物
Lu et al. Afatinib-loaded immunoliposomes functionalized with cetuximab: A novel strategy targeting the epidermal growth factor receptor for treatment of non-small-cell lung cancer
US20040022842A1 (en) Liposome preparations containing oxaliplatin
Liu et al. Effective co-encapsulation of doxorubicin and irinotecan for synergistic therapy using liposomes prepared with triethylammonium sucrose octasulfate as drug trapping agent
WO2013008240A2 (en) Liposomes co-encapsulating a bisphosphonate and an amphipathic agent
Marzban et al. Optimizing the therapeutic efficacy of cisplatin PEGylated liposomes via incorporation of different DPPG ratios: In vitro and in vivo studies
CN116635009A (zh) 用于递送抗癌剂的具有改进的治疗指数的组合物和方法
WO2008038291A1 (en) Combination of liposomal anti-cancer drugs and lysosome/endosome ph increasing agents for therapy
CN115605196A (zh) 用于治疗癌症和癌症耐药性的脂质体制剂
Orthmann et al. Improved treatment of MT-3 breast cancer and brain metastases in a mouse xenograft by LRP-targeted oxaliplatin liposomes
Webb et al. In vitro and in vivo characterization of a combination chemotherapy formulation consisting of vinorelbine and phosphatidylserine
CN108883068A (zh) 使用紫杉烷的阳离子微脂体制剂、紫杉烷的非微脂体制剂和其他活性药剂合并治疗乳癌的方法
US10925831B2 (en) Liposomal formulations of platinum-acridine anticancer agents and methods thereof
WO2022124898A1 (en) Auristatin-loaded liposomes and uses thereof.
CN114099469A (zh) 一种复合纳米药物载体及其制备方法和应用
US20070292497A1 (en) Method for treating micrometastatic tumors
HK40086650A (zh) 用於治疗癌症和癌症耐药性的脂质体制剂
Kamel et al. Vesicular Nanosystem as a Promising Platform for the Management of Cancer
US20200390702A1 (en) Liposomal taxanes for treatment of sclc
Rathi Development and Characterization of Functionalized Nanoconstructs for Effective Treatment of Lung Cancer
Casagrande Anticancer activity of liposomal cisplatin in preclinical models of cervical and ovarian cancer