CN101522172A - 癌症治疗 - Google Patents

癌症治疗 Download PDF

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Publication number
CN101522172A
CN101522172A CNA2007800139281A CN200780013928A CN101522172A CN 101522172 A CN101522172 A CN 101522172A CN A2007800139281 A CNA2007800139281 A CN A2007800139281A CN 200780013928 A CN200780013928 A CN 200780013928A CN 101522172 A CN101522172 A CN 101522172A
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CN
China
Prior art keywords
oxaliplatin
liposome
cancer
liposomes
drug
Prior art date
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Pending
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CNA2007800139281A
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English (en)
Chinese (zh)
Inventor
帕斯尼奥斯·布利卡斯
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Individual
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Publication of CN101522172A publication Critical patent/CN101522172A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA2007800139281A 2006-03-03 2007-03-05 癌症治疗 Pending CN101522172A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GR20060100144A GR20060100144A (el) 2006-03-03 2006-03-03 Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene
GR20060100144 2006-03-03

Publications (1)

Publication Number Publication Date
CN101522172A true CN101522172A (zh) 2009-09-02

Family

ID=38325437

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800139281A Pending CN101522172A (zh) 2006-03-03 2007-03-05 癌症治疗

Country Status (17)

Country Link
US (1) US20090053302A1 (enExample)
EP (1) EP2001441A2 (enExample)
JP (1) JP2009528340A (enExample)
KR (1) KR20090023548A (enExample)
CN (1) CN101522172A (enExample)
AU (1) AU2007220263A1 (enExample)
BR (1) BRPI0707059A2 (enExample)
CA (1) CA2644566A1 (enExample)
EA (1) EA200801912A1 (enExample)
GR (1) GR20060100144A (enExample)
MA (1) MA30314B1 (enExample)
MX (1) MX2008011263A (enExample)
NO (1) NO20083927L (enExample)
RS (1) RS20080388A (enExample)
TN (1) TNSN08345A1 (enExample)
WO (1) WO2007099377A2 (enExample)
ZA (1) ZA200807934B (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102133176A (zh) * 2011-03-22 2011-07-27 济南宏瑞创博医药科技开发有限公司 一种奥沙利铂胶束制剂及其制备方法及应用
CN103622912A (zh) * 2013-12-05 2014-03-12 常州金远药业制造有限公司 盐酸多柔比星-多西他赛或紫杉醇脂质体制剂及其制备方法
CN106074379A (zh) * 2016-07-11 2016-11-09 中国科学院上海药物研究所 聚乙二醇化奥沙利铂前药及其制备方法和用途
CN112656764A (zh) * 2020-12-28 2021-04-16 吉林大学 一种紫杉醇铂类共载靶向长循环脂质体及应用
CN114814023A (zh) * 2022-04-24 2022-07-29 江苏省中医院 脂质分子在作为胃癌化疗药耐药的预测性标志物中的应用

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9186322B2 (en) * 2002-08-02 2015-11-17 Insmed Incorporated Platinum aggregates and process for producing the same
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
KR20080094473A (ko) * 2007-04-20 2008-10-23 한국화학연구원 음이온성 지질나노입자 및 이의 제조방법
ES2465477T3 (es) * 2008-01-28 2014-06-05 Nanocarrier Co., Ltd. Composición farmacéutica y fármaco combinado
TWI468188B (zh) * 2008-01-30 2015-01-11 Univ Tokushima Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation
EP2259844A4 (en) * 2008-03-05 2012-02-01 Vicus Therapeutics Llc COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGICAL THERAPIES
EP2123258A1 (en) * 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes for drug delivery
WO2010138550A1 (en) * 2009-05-27 2010-12-02 Northeastern University Conjugated nanodelivery vehicles
AU2010296180B2 (en) * 2009-09-21 2016-05-05 Bio-Synectics, Inc Oxaliplatin nanoparticles and method for preparing same
JP5817053B2 (ja) * 2010-04-02 2015-11-18 国立大学法人 千葉大学 腫瘍特異性を有するリポソーム
JP5378469B2 (ja) 2011-08-11 2013-12-25 学校法人 日本歯科大学 医療用薬剤
SG10201701063WA (en) * 2012-08-10 2017-04-27 Taiho Pharmaceutical Co Ltd Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same
MA37931A1 (fr) * 2012-08-13 2016-07-29 Teni Boulikas Procédés améliorés permettant de traiter un cancer avec une toxicité rénale réduite
KR20150044838A (ko) * 2012-08-13 2015-04-27 레귤론, 인코퍼레이티드. 리포플라틴을 이용한 암 치료방법
EP2892524B1 (en) 2012-09-04 2020-11-25 Eleison Pharmaceuticals, LLC Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin
EA023757B1 (ru) * 2012-12-24 2016-07-29 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы оксалиплатина
EP2968144A1 (en) * 2013-03-13 2016-01-20 Mallinckrodt LLC Liposome oxaliplatin compositions for cancer therapy
UA117581C2 (uk) * 2013-03-27 2018-08-27 Тайхо Фармасьютікал Ко., Лтд. Протипухлинний лікарський засіб, який включає низькодозований гідрохлориду іринотекану гідрат
CA2976526A1 (en) * 2015-02-13 2016-08-18 Trendmed Co., Ltd. Compositions and methods of tumor treatment utilizing nanoparticles
WO2016141161A1 (en) 2015-03-03 2016-09-09 Cureport, Inc. Dual loaded liposomal pharmaceutical formulations
WO2016141167A1 (en) 2015-03-03 2016-09-09 Cureport, Inc. Combination liposomal pharmaceutical formulations
KR101687735B1 (ko) * 2015-09-18 2016-12-19 서울대학교 산학협력단 신규의 동결건조보조제 및 새로운 인지질 용해용 혼합용매를 이용한 리포좀 동결분체의 제조방법
WO2017192502A1 (en) * 2016-05-03 2017-11-09 The American University In Cairo Liposomal delivery systems for oxaliplatin and in dual drug delivery in combination with chemo-sensitizing and chemo-therapeutic agents
US10940112B2 (en) 2016-05-04 2021-03-09 L.E.A.F. Holdings Group Llc Targeted liposomal gemcitabine compositions and methods thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2046997C (en) * 1990-07-16 2000-12-12 Hiroshi Kikuchi Liposomal products
US6060080A (en) * 1990-07-16 2000-05-09 Daiichi Pharmaceutical Co., Ltd. Liposomal products
US6511676B1 (en) * 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
CN1254234C (zh) * 2000-06-09 2006-05-03 莱古伦公司 质粒dna(lipogenestm)和含细胞核定位信号/促融合肽缀合物的治疗剂包封到定向脂质体复合体中
CA2383259A1 (en) * 2002-04-23 2003-10-23 Celator Technologies Inc. Synergistic compositions
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
JP3415131B1 (ja) * 2002-06-03 2003-06-09 メビオファーム株式会社 リポソーム製剤
EP1545459A4 (en) * 2002-08-02 2007-08-22 Transave Inc PLATINUM AGGREGATES, AND METHOD FOR MANUFACTURING THE SAME
AU2004235781A1 (en) * 2003-05-02 2004-11-18 Aronex Pharmaceuticals, Inc. Lipid platinum complexes and methods of use thereof
WO2005000266A2 (en) * 2003-05-22 2005-01-06 Neopharm, Inc. Liposomal formulations comprising a combination of two or more active agents

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102133176A (zh) * 2011-03-22 2011-07-27 济南宏瑞创博医药科技开发有限公司 一种奥沙利铂胶束制剂及其制备方法及应用
CN102133176B (zh) * 2011-03-22 2012-09-05 济南宏瑞创博医药科技开发有限公司 一种奥沙利铂胶束制剂及其制备方法及应用
CN103622912A (zh) * 2013-12-05 2014-03-12 常州金远药业制造有限公司 盐酸多柔比星-多西他赛或紫杉醇脂质体制剂及其制备方法
CN103622912B (zh) * 2013-12-05 2016-02-24 常州金远药业制造有限公司 盐酸多柔比星-多西他赛或紫杉醇脂质体制剂及其制备方法
CN106074379A (zh) * 2016-07-11 2016-11-09 中国科学院上海药物研究所 聚乙二醇化奥沙利铂前药及其制备方法和用途
CN106074379B (zh) * 2016-07-11 2019-01-25 中国科学院上海药物研究所 聚乙二醇化奥沙利铂前药及其制备方法和用途
CN112656764A (zh) * 2020-12-28 2021-04-16 吉林大学 一种紫杉醇铂类共载靶向长循环脂质体及应用
CN114814023A (zh) * 2022-04-24 2022-07-29 江苏省中医院 脂质分子在作为胃癌化疗药耐药的预测性标志物中的应用

Also Published As

Publication number Publication date
MA30314B1 (fr) 2009-04-01
MX2008011263A (es) 2008-12-12
ZA200807934B (en) 2009-11-25
BRPI0707059A2 (pt) 2011-04-19
AU2007220263A1 (en) 2007-09-07
EA200801912A1 (ru) 2009-02-27
CA2644566A1 (en) 2007-09-07
JP2009528340A (ja) 2009-08-06
RS20080388A (sr) 2009-07-15
WO2007099377A2 (en) 2007-09-07
GR20060100144A (el) 2007-10-17
EP2001441A2 (en) 2008-12-17
TNSN08345A1 (en) 2009-12-29
US20090053302A1 (en) 2009-02-26
KR20090023548A (ko) 2009-03-05
WO2007099377A3 (en) 2008-04-17
NO20083927L (no) 2008-09-15

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Application publication date: 20090902