GR20060100144A - Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene - Google Patents
Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h geneInfo
- Publication number
- GR20060100144A GR20060100144A GR20060100144A GR20060100144A GR20060100144A GR 20060100144 A GR20060100144 A GR 20060100144A GR 20060100144 A GR20060100144 A GR 20060100144A GR 20060100144 A GR20060100144 A GR 20060100144A GR 20060100144 A GR20060100144 A GR 20060100144A
- Authority
- GR
- Greece
- Prior art keywords
- genes
- pharmaceutical preparations
- encapsulation
- liposomes
- cancer treatment
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 5
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 3
- DWAFYCQODLXJNR-BNTLRKBRSA-L oxaliplatin Chemical compound O1C(=O)C(=O)O[Pt]11N[C@@H]2CCCC[C@H]2N1 DWAFYCQODLXJNR-BNTLRKBRSA-L 0.000 title abstract 3
- 229960001756 oxaliplatin Drugs 0.000 title abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 238000005538 encapsulation Methods 0.000 title abstract 2
- 239000002245 particle Substances 0.000 title 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 238000002648 combination therapy Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000010253 intravenous injection Methods 0.000 abstract 1
- 230000036210 malignancy Effects 0.000 abstract 1
- 238000009097 single-agent therapy Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20060100144A GR20060100144A (el) | 2006-03-03 | 2006-03-03 | Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene |
| PCT/GR2007/000015 WO2007099377A2 (en) | 2006-03-03 | 2007-03-05 | Cancer treatments |
| US12/281,541 US20090053302A1 (en) | 2006-03-03 | 2007-03-05 | Cancer treatments |
| EP07712997A EP2001441A2 (en) | 2006-03-03 | 2007-03-05 | Cancer treatments |
| RSP-2008/0388A RS20080388A (sr) | 2006-03-03 | 2007-03-05 | Lečenje malignih bolesti |
| EA200801912A EA200801912A1 (ru) | 2006-03-03 | 2007-03-05 | Лечение рака |
| JP2008556861A JP2009528340A (ja) | 2006-03-03 | 2007-03-05 | 癌治療 |
| BRPI0707059-4A BRPI0707059A2 (pt) | 2006-03-03 | 2007-03-05 | método de formação de uma micela que compreende oxaliplatina, método de encapsulação de oxaliplatina em um lipossomo, micela, lipossomo, lipossomo que compreende uma quantidade eficaz de oxaliplatina, uso de um lipossomo, método de tratamento de cáncer e terapia de combinação |
| CA002644566A CA2644566A1 (en) | 2006-03-03 | 2007-03-05 | Cancer treatments |
| MX2008011263A MX2008011263A (es) | 2006-03-03 | 2007-03-05 | Tratamientos para cancer. |
| AU2007220263A AU2007220263A1 (en) | 2006-03-03 | 2007-03-05 | Cancer treatments |
| KR1020087024248A KR20090023548A (ko) | 2006-03-03 | 2007-03-05 | 암 치료 |
| CNA2007800139281A CN101522172A (zh) | 2006-03-03 | 2007-03-05 | 癌症治疗 |
| MA31204A MA30314B1 (fr) | 2006-03-03 | 2008-09-02 | Traitements contre le cancer |
| TNP2008000345A TNSN08345A1 (en) | 2006-03-03 | 2008-09-03 | Cancer treatments |
| NO20083927A NO20083927L (no) | 2006-03-03 | 2008-09-15 | Kreftbehandlinger |
| ZA200807934A ZA200807934B (en) | 2006-03-03 | 2008-09-16 | Cancer treatments |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20060100144A GR20060100144A (el) | 2006-03-03 | 2006-03-03 | Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR20060100144A true GR20060100144A (el) | 2007-10-17 |
Family
ID=38325437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20060100144A GR20060100144A (el) | 2006-03-03 | 2006-03-03 | Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20090053302A1 (enExample) |
| EP (1) | EP2001441A2 (enExample) |
| JP (1) | JP2009528340A (enExample) |
| KR (1) | KR20090023548A (enExample) |
| CN (1) | CN101522172A (enExample) |
| AU (1) | AU2007220263A1 (enExample) |
| BR (1) | BRPI0707059A2 (enExample) |
| CA (1) | CA2644566A1 (enExample) |
| EA (1) | EA200801912A1 (enExample) |
| GR (1) | GR20060100144A (enExample) |
| MA (1) | MA30314B1 (enExample) |
| MX (1) | MX2008011263A (enExample) |
| NO (1) | NO20083927L (enExample) |
| RS (1) | RS20080388A (enExample) |
| TN (1) | TNSN08345A1 (enExample) |
| WO (1) | WO2007099377A2 (enExample) |
| ZA (1) | ZA200807934B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9186322B2 (en) * | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
| US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| KR20080094473A (ko) * | 2007-04-20 | 2008-10-23 | 한국화학연구원 | 음이온성 지질나노입자 및 이의 제조방법 |
| ES2465477T3 (es) * | 2008-01-28 | 2014-06-05 | Nanocarrier Co., Ltd. | Composición farmacéutica y fármaco combinado |
| TWI468188B (zh) * | 2008-01-30 | 2015-01-11 | Univ Tokushima | Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation |
| EP2259844A4 (en) * | 2008-03-05 | 2012-02-01 | Vicus Therapeutics Llc | COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGICAL THERAPIES |
| EP2123258A1 (en) * | 2008-05-23 | 2009-11-25 | Liplasome Pharma A/S | Liposomes for drug delivery |
| WO2010138550A1 (en) * | 2009-05-27 | 2010-12-02 | Northeastern University | Conjugated nanodelivery vehicles |
| AU2010296180B2 (en) * | 2009-09-21 | 2016-05-05 | Bio-Synectics, Inc | Oxaliplatin nanoparticles and method for preparing same |
| JP5817053B2 (ja) * | 2010-04-02 | 2015-11-18 | 国立大学法人 千葉大学 | 腫瘍特異性を有するリポソーム |
| CN102133176B (zh) * | 2011-03-22 | 2012-09-05 | 济南宏瑞创博医药科技开发有限公司 | 一种奥沙利铂胶束制剂及其制备方法及应用 |
| JP5378469B2 (ja) | 2011-08-11 | 2013-12-25 | 学校法人 日本歯科大学 | 医療用薬剤 |
| SG10201701063WA (en) * | 2012-08-10 | 2017-04-27 | Taiho Pharmaceutical Co Ltd | Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same |
| MA37931A1 (fr) * | 2012-08-13 | 2016-07-29 | Teni Boulikas | Procédés améliorés permettant de traiter un cancer avec une toxicité rénale réduite |
| KR20150044838A (ko) * | 2012-08-13 | 2015-04-27 | 레귤론, 인코퍼레이티드. | 리포플라틴을 이용한 암 치료방법 |
| EP2892524B1 (en) | 2012-09-04 | 2020-11-25 | Eleison Pharmaceuticals, LLC | Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin |
| EA023757B1 (ru) * | 2012-12-24 | 2016-07-29 | Общество С Ограниченной Ответственностью "Технология Лекарств" | Способ получения липосомальной формы оксалиплатина |
| EP2968144A1 (en) * | 2013-03-13 | 2016-01-20 | Mallinckrodt LLC | Liposome oxaliplatin compositions for cancer therapy |
| UA117581C2 (uk) * | 2013-03-27 | 2018-08-27 | Тайхо Фармасьютікал Ко., Лтд. | Протипухлинний лікарський засіб, який включає низькодозований гідрохлориду іринотекану гідрат |
| CN103622912B (zh) * | 2013-12-05 | 2016-02-24 | 常州金远药业制造有限公司 | 盐酸多柔比星-多西他赛或紫杉醇脂质体制剂及其制备方法 |
| CA2976526A1 (en) * | 2015-02-13 | 2016-08-18 | Trendmed Co., Ltd. | Compositions and methods of tumor treatment utilizing nanoparticles |
| WO2016141161A1 (en) | 2015-03-03 | 2016-09-09 | Cureport, Inc. | Dual loaded liposomal pharmaceutical formulations |
| WO2016141167A1 (en) | 2015-03-03 | 2016-09-09 | Cureport, Inc. | Combination liposomal pharmaceutical formulations |
| KR101687735B1 (ko) * | 2015-09-18 | 2016-12-19 | 서울대학교 산학협력단 | 신규의 동결건조보조제 및 새로운 인지질 용해용 혼합용매를 이용한 리포좀 동결분체의 제조방법 |
| WO2017192502A1 (en) * | 2016-05-03 | 2017-11-09 | The American University In Cairo | Liposomal delivery systems for oxaliplatin and in dual drug delivery in combination with chemo-sensitizing and chemo-therapeutic agents |
| US10940112B2 (en) | 2016-05-04 | 2021-03-09 | L.E.A.F. Holdings Group Llc | Targeted liposomal gemcitabine compositions and methods thereof |
| CN106074379B (zh) * | 2016-07-11 | 2019-01-25 | 中国科学院上海药物研究所 | 聚乙二醇化奥沙利铂前药及其制备方法和用途 |
| CN112656764B (zh) * | 2020-12-28 | 2022-09-02 | 吉林大学 | 一种紫杉醇铂类共载靶向长循环脂质体及应用 |
| CN114814023B (zh) * | 2022-04-24 | 2024-07-30 | 江苏省中医院 | 脂质分子在作为胃癌化疗药耐药的预测性标志物中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2046997C (en) * | 1990-07-16 | 2000-12-12 | Hiroshi Kikuchi | Liposomal products |
| US6060080A (en) * | 1990-07-16 | 2000-05-09 | Daiichi Pharmaceutical Co., Ltd. | Liposomal products |
| US6511676B1 (en) * | 1999-11-05 | 2003-01-28 | Teni Boulikas | Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes |
| CN1254234C (zh) * | 2000-06-09 | 2006-05-03 | 莱古伦公司 | 质粒dna(lipogenestm)和含细胞核定位信号/促融合肽缀合物的治疗剂包封到定向脂质体复合体中 |
| CA2383259A1 (en) * | 2002-04-23 | 2003-10-23 | Celator Technologies Inc. | Synergistic compositions |
| US20040022842A1 (en) * | 2002-06-03 | 2004-02-05 | Mebiopharm Co., Ltd. | Liposome preparations containing oxaliplatin |
| JP3415131B1 (ja) * | 2002-06-03 | 2003-06-09 | メビオファーム株式会社 | リポソーム製剤 |
| EP1545459A4 (en) * | 2002-08-02 | 2007-08-22 | Transave Inc | PLATINUM AGGREGATES, AND METHOD FOR MANUFACTURING THE SAME |
| AU2004235781A1 (en) * | 2003-05-02 | 2004-11-18 | Aronex Pharmaceuticals, Inc. | Lipid platinum complexes and methods of use thereof |
| WO2005000266A2 (en) * | 2003-05-22 | 2005-01-06 | Neopharm, Inc. | Liposomal formulations comprising a combination of two or more active agents |
-
2006
- 2006-03-03 GR GR20060100144A patent/GR20060100144A/el not_active IP Right Cessation
-
2007
- 2007-03-05 EA EA200801912A patent/EA200801912A1/ru unknown
- 2007-03-05 MX MX2008011263A patent/MX2008011263A/es not_active Application Discontinuation
- 2007-03-05 RS RSP-2008/0388A patent/RS20080388A/sr unknown
- 2007-03-05 AU AU2007220263A patent/AU2007220263A1/en not_active Abandoned
- 2007-03-05 CA CA002644566A patent/CA2644566A1/en not_active Abandoned
- 2007-03-05 EP EP07712997A patent/EP2001441A2/en not_active Withdrawn
- 2007-03-05 BR BRPI0707059-4A patent/BRPI0707059A2/pt not_active IP Right Cessation
- 2007-03-05 CN CNA2007800139281A patent/CN101522172A/zh active Pending
- 2007-03-05 WO PCT/GR2007/000015 patent/WO2007099377A2/en not_active Ceased
- 2007-03-05 US US12/281,541 patent/US20090053302A1/en not_active Abandoned
- 2007-03-05 KR KR1020087024248A patent/KR20090023548A/ko not_active Ceased
- 2007-03-05 JP JP2008556861A patent/JP2009528340A/ja active Pending
-
2008
- 2008-09-02 MA MA31204A patent/MA30314B1/fr unknown
- 2008-09-03 TN TNP2008000345A patent/TNSN08345A1/en unknown
- 2008-09-15 NO NO20083927A patent/NO20083927L/no not_active Application Discontinuation
- 2008-09-16 ZA ZA200807934A patent/ZA200807934B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MA30314B1 (fr) | 2009-04-01 |
| MX2008011263A (es) | 2008-12-12 |
| ZA200807934B (en) | 2009-11-25 |
| BRPI0707059A2 (pt) | 2011-04-19 |
| AU2007220263A1 (en) | 2007-09-07 |
| EA200801912A1 (ru) | 2009-02-27 |
| CA2644566A1 (en) | 2007-09-07 |
| JP2009528340A (ja) | 2009-08-06 |
| RS20080388A (sr) | 2009-07-15 |
| WO2007099377A2 (en) | 2007-09-07 |
| EP2001441A2 (en) | 2008-12-17 |
| TNSN08345A1 (en) | 2009-12-29 |
| CN101522172A (zh) | 2009-09-02 |
| US20090053302A1 (en) | 2009-02-26 |
| KR20090023548A (ko) | 2009-03-05 |
| WO2007099377A3 (en) | 2008-04-17 |
| NO20083927L (no) | 2008-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ML | Lapse due to non-payment of fees |
Effective date: 20151002 |