HK1217085A1 - 包封在顆粒中的靶向綴合物及其製劑 - Google Patents
包封在顆粒中的靶向綴合物及其製劑Info
- Publication number
- HK1217085A1 HK1217085A1 HK16104731.8A HK16104731A HK1217085A1 HK 1217085 A1 HK1217085 A1 HK 1217085A1 HK 16104731 A HK16104731 A HK 16104731A HK 1217085 A1 HK1217085 A1 HK 1217085A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- formulations
- particles
- targeted conjugates
- encapsulated
- conjugates encapsulated
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
- A61K47/6929—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
- A61K47/551—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds one of the codrug's components being a vitamin, e.g. niacinamide, vitamin B3, cobalamin, vitamin B12, folate, vitamin A or retinoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Nanotechnology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261746866P | 2012-12-28 | 2012-12-28 | |
PCT/US2013/078361 WO2014106208A1 (en) | 2012-12-28 | 2013-12-30 | Targeted conjugates encapsulated in particles and formulations thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1217085A1 true HK1217085A1 (zh) | 2016-12-23 |
Family
ID=49998713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16104731.8A HK1217085A1 (zh) | 2012-12-28 | 2016-04-26 | 包封在顆粒中的靶向綴合物及其製劑 |
Country Status (14)
Country | Link |
---|---|
US (5) | US20140187501A1 (zh) |
EP (1) | EP2938364A1 (zh) |
JP (2) | JP6118914B2 (zh) |
KR (1) | KR20150100706A (zh) |
CN (2) | CN110179995A (zh) |
AU (2) | AU2013369982B2 (zh) |
CA (1) | CA2896571C (zh) |
HK (1) | HK1217085A1 (zh) |
IL (1) | IL238994B (zh) |
MX (1) | MX360098B (zh) |
MY (1) | MY172519A (zh) |
SG (2) | SG11201504235UA (zh) |
WO (1) | WO2014106208A1 (zh) |
ZA (1) | ZA201504109B (zh) |
Families Citing this family (39)
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CN104873982A (zh) | 2007-08-17 | 2015-09-02 | 普渡研究基金会 | Psma结合配体-接头缀合物及其使用方法 |
US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
MY171561A (en) | 2012-11-15 | 2019-10-18 | Endocyte Inc | Conjugates for treating diseases caused by psma expressing cells |
AU2013369982B2 (en) * | 2012-12-28 | 2016-11-17 | Tva (Abc), Llc | Targeted conjugates encapsulated in particles and formulations thereof |
DE202014011593U1 (de) | 2013-10-18 | 2023-08-23 | Novartis Ag | Markierte Inhibitoren des prostataspezifischen Membranantigens (PSMA), deren Verwendung als bildgebende Mittel und pharmazeutische Wirkstoffe für die Behandlung von Prostatakrebs |
EP3089745A4 (en) * | 2013-12-31 | 2017-05-17 | Placon Therapeutics, Inc. | Compounds, compositions, and methods for the treatment of cancers |
RU2718922C2 (ru) * | 2014-12-01 | 2020-04-15 | Инноап Фарма, С.Л. | Наночастицы для инкапсулирования соединений, их получение и применение |
US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
EP3265063A4 (en) | 2015-03-03 | 2018-11-07 | Cureport, Inc. | Dual loaded liposomal pharmaceutical formulations |
US9895313B2 (en) | 2015-03-03 | 2018-02-20 | Cureport, Inc. | Combination liposomal pharmaceutical formulations |
BR112017028552A2 (pt) * | 2015-06-30 | 2018-09-04 | Tarveda Therapeutics Inc | partículas e conjugados direcionados e formulações dos mesmos |
WO2017023779A1 (en) * | 2015-07-31 | 2017-02-09 | Tarveda Therapeutics, Inc. | Compositions and methods for immuno-oncology therapies |
US20180258411A1 (en) * | 2015-09-25 | 2018-09-13 | Tarveda Therapeutics, Inc. | Compositions and methods for genome editing |
MY197061A (en) | 2015-09-30 | 2023-05-23 | Deutsches Krebsforsch | Improved 18f-tagged inhibitors of prostate specific membrane antigen (psma) and their use as imaging agents for prostate cancer |
US11065272B2 (en) | 2015-10-06 | 2021-07-20 | University Of Washington | Oxygen reactive polymers for treatment of traumatic brain injury |
AU2016343817B2 (en) * | 2015-10-28 | 2021-05-27 | Tva (Abc), Llc | SSTR-targeted conjugates and particles and formulations thereof |
CN106957422B (zh) * | 2015-12-31 | 2020-07-07 | 南京绿叶制药有限公司 | 一种磷脂-聚乙二醇-psma配体化合物及其制备方法 |
KR20180112060A (ko) | 2016-02-23 | 2018-10-11 | 타베다 세라퓨틱스, 인코포레이티드 | Hsp90 표적화된 접합체 및 이의 입자 및 제형 |
US10744212B2 (en) | 2016-03-14 | 2020-08-18 | General Electric Company | Topical application of nerve labeling dyes for image-guided surgery |
WO2018023005A1 (en) * | 2016-07-28 | 2018-02-01 | Waters Technologies Corporation | Encapsulated pre-analytic workflows for flow-through devices, liquid chromatography and mass spectrometric analysis |
WO2018022957A1 (en) * | 2016-07-29 | 2018-02-01 | Tarveda Therapeutics, Inc. | T cell binding conjugates and methods of use |
WO2018112176A1 (en) * | 2016-12-14 | 2018-06-21 | Tarveda Therapeutics, Inc. | Hsp90-targeting conjugates and formulations thereof |
BR112019015145A2 (pt) * | 2017-01-24 | 2020-03-24 | Société des Produits Nestlé S.A. | Composições que compreendem anticorpos anti-fel d1 e métodos para reduzir pelo menos um sintoma da alergia de humanos a gatos |
WO2019023295A1 (en) * | 2017-07-27 | 2019-01-31 | Saint Louis University | HUMAN EPIDERMAL GROWTH FACTOR MODIFIED BY FATTY ACID |
WO2019094648A1 (en) * | 2017-11-08 | 2019-05-16 | L.E.A.F. Holdings Group Llc | Platinum complexes and uses thereof |
EP3801031A4 (en) * | 2018-05-27 | 2021-08-11 | The State of Israel, Ministry of Agriculture & Rural Development Agricultural Research Organization | SINGLE CELL ENCAPSULATION USING PICKERING EMULSION FOR BIO-PESTICIDE APPLICATION |
WO2019241853A1 (en) * | 2018-06-21 | 2019-12-26 | NanoMed Holdings Pty Ltd | Platinum-based amphiphile prodrugs |
WO2020005767A1 (en) * | 2018-06-25 | 2020-01-02 | The Board Of Regents Of The University Of Oklahoma | Conjugates with internal and terminal-end heparosan linkages |
GB2592504B (en) * | 2018-09-04 | 2023-02-15 | Univ Texas | Compositions and methods for organ specific delivery of nucleic acids |
CA3111484A1 (en) | 2018-09-04 | 2020-03-12 | The Board Of Regents Of The University Of Texas System | Compositions and methods for organ specific delivery of nucleic acids |
CN109289053B (zh) * | 2018-09-30 | 2020-10-13 | 浙江大学 | 卡巴他赛-寡/聚乳酸偶联前药、制剂及其制备方法与应用 |
CA3143373A1 (en) * | 2019-06-25 | 2020-12-30 | Tarveda Therapeutics, Inc. | Sstr-targeted conjugates and formulations thereof |
CN110974972B (zh) * | 2019-12-03 | 2023-01-20 | 沈阳药科大学 | 难溶性药物的弱酸性衍生物及其脂质体制剂 |
EP4106819A1 (en) | 2020-02-21 | 2022-12-28 | Silverback Therapeutics, Inc. | Nectin-4 antibody conjugates and uses thereof |
KR20210116339A (ko) * | 2020-03-16 | 2021-09-27 | 주식회사 바이오이즈 | 표적화 압타머 접합체를 캡슐화한 입자 및 이의 용도 |
CN111888332B (zh) * | 2020-06-19 | 2023-07-25 | 杭州师范大学 | 一种卡巴他赛柔性乳剂及其制备方法 |
US11896713B2 (en) * | 2020-10-22 | 2024-02-13 | Rutgers, The State University Of New Jersey | Strategies to enhance lung cancer treatment |
CN113087787B (zh) * | 2021-05-19 | 2023-03-21 | 广西医科大学第二附属医院(广西医科大学第二临床医学院) | 一种蚯蚓血红蛋白分离及纯化方法 |
EP4282435A1 (en) * | 2022-05-23 | 2023-11-29 | Danmarks Tekniske Universitet | Formulations of active pharmaceutical ingredients and excipients in icells via hydrophobic ion pairing |
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US20030049203A1 (en) * | 2001-08-31 | 2003-03-13 | Elmaleh David R. | Targeted nucleic acid constructs and uses related thereto |
US20030109682A1 (en) * | 2001-09-07 | 2003-06-12 | Daniel Santi | Maytansines and maytansine conjugates |
AU2003304108B2 (en) * | 2002-10-30 | 2007-03-22 | Spherics, Inc. | Nanoparticulate bioactive agents |
US7232805B2 (en) * | 2003-09-10 | 2007-06-19 | Inflabloc Pharmaceuticals, Inc. | Cobalamin conjugates for anti-tumor therapy |
WO2005118612A1 (en) * | 2004-06-04 | 2005-12-15 | Sonus Pharmaceuticals, Inc. | Cholesterol/bile acid/bile acid derivative-modified therapeutic anti-cancer drugs |
AR051922A1 (es) * | 2004-07-27 | 2007-02-21 | Gilead Sciences Inc | Analogos de fosfonatos de compuestos inhibidores de hiv |
EP1700608A1 (en) * | 2005-03-10 | 2006-09-13 | Schering AG | Chelators for radioactively labeled conjugates comprising a stabilizing sidechain |
EP1745802A1 (en) * | 2005-07-20 | 2007-01-24 | Kreatech Biotechnology B.V. | Method of conjugating therapeutic compounds to cell targeting moieties via metal complexes |
CA2652280C (en) * | 2006-05-15 | 2014-01-28 | Massachusetts Institute Of Technology | Polymers for functional particles |
WO2008121949A1 (en) * | 2007-03-30 | 2008-10-09 | Bind Biosciences, Inc. | Cancer cell targeting using nanoparticles |
AU2008312457B2 (en) * | 2007-10-19 | 2014-04-17 | Genentech, Inc. | Cysteine engineered anti-TENB2 antibodies and antibody drug conjugates |
EP2303337A4 (en) * | 2008-06-13 | 2014-09-03 | Cedars Sinai Medical Center | MEDICAMENT-LIGAND SMALL MOLECULE CONJUGATES FOR TARGETED CANCER TREATMENT |
WO2009158633A1 (en) * | 2008-06-26 | 2009-12-30 | Curators Of The University Of Missouri On Behalf Of The University Of Missouri-Kansas City | Drug conjugates |
US8603532B2 (en) * | 2008-10-20 | 2013-12-10 | Massachusetts Institute Of Technology | Nanostructures for drug delivery |
US8470980B2 (en) * | 2009-09-09 | 2013-06-25 | Centrose, Llc | Extracellular targeted drug conjugates |
CN103492489A (zh) * | 2010-04-15 | 2014-01-01 | 欧利加希斯公司 | 高分子量的含两性离子的聚合物 |
WO2012030745A1 (en) * | 2010-08-30 | 2012-03-08 | Access Pharmaecuticals, Inc | MULTIVITAMIN TARGETING OF RNAi THERAPEUTICS |
FR2967581B1 (fr) * | 2010-11-19 | 2012-12-28 | Sanofi Aventis | Conjugues polymeriques de principes actifs, leur procede de preparation et leurs intermediaires polymeriques |
EP2694964B1 (en) * | 2011-04-07 | 2019-06-26 | The Scripps Research Institute | High-throughput screening for compounds modulating levels of cellular macromolecules |
US20140308363A1 (en) * | 2011-05-31 | 2014-10-16 | Bind Therapeutics, Inc. | Drug loaded polymeric nanoparticles and methods of making and using same |
AU2013369982B2 (en) * | 2012-12-28 | 2016-11-17 | Tva (Abc), Llc | Targeted conjugates encapsulated in particles and formulations thereof |
-
2013
- 2013-12-30 AU AU2013369982A patent/AU2013369982B2/en not_active Ceased
- 2013-12-30 KR KR1020157017269A patent/KR20150100706A/ko not_active Application Discontinuation
- 2013-12-30 SG SG11201504235UA patent/SG11201504235UA/en unknown
- 2013-12-30 MY MYPI2015001403A patent/MY172519A/en unknown
- 2013-12-30 CA CA2896571A patent/CA2896571C/en active Active
- 2013-12-30 US US14/144,263 patent/US20140187501A1/en not_active Abandoned
- 2013-12-30 CN CN201910388193.5A patent/CN110179995A/zh active Pending
- 2013-12-30 SG SG10201705514WA patent/SG10201705514WA/en unknown
- 2013-12-30 CN CN201380068680.4A patent/CN104936622B/zh not_active Expired - Fee Related
- 2013-12-30 MX MX2015008503A patent/MX360098B/es active IP Right Grant
- 2013-12-30 EP EP13822073.6A patent/EP2938364A1/en not_active Withdrawn
- 2013-12-30 JP JP2015550852A patent/JP6118914B2/ja not_active Expired - Fee Related
- 2013-12-30 WO PCT/US2013/078361 patent/WO2014106208A1/en active Application Filing
-
2015
- 2015-05-25 IL IL238994A patent/IL238994B/en active IP Right Grant
- 2015-06-08 ZA ZA201504109A patent/ZA201504109B/en unknown
- 2015-11-23 US US14/949,138 patent/US20160074526A1/en not_active Abandoned
-
2016
- 2016-04-26 HK HK16104731.8A patent/HK1217085A1/zh unknown
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2017
- 2017-01-25 AU AU2017200510A patent/AU2017200510A1/en not_active Abandoned
- 2017-03-27 JP JP2017060849A patent/JP2017105855A/ja active Pending
- 2017-09-05 US US15/695,214 patent/US20180021454A1/en not_active Abandoned
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2019
- 2019-12-20 US US16/722,913 patent/US20200121808A1/en not_active Abandoned
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2022
- 2022-05-23 US US17/750,865 patent/US20220288229A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
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KR20150100706A (ko) | 2015-09-02 |
JP6118914B2 (ja) | 2017-04-19 |
EP2938364A1 (en) | 2015-11-04 |
SG10201705514WA (en) | 2017-08-30 |
IL238994B (en) | 2019-07-31 |
SG11201504235UA (en) | 2015-07-30 |
IL238994A0 (en) | 2015-07-30 |
US20140187501A1 (en) | 2014-07-03 |
US20160074526A1 (en) | 2016-03-17 |
CN104936622B (zh) | 2019-05-28 |
AU2017200510A1 (en) | 2017-02-16 |
CA2896571A1 (en) | 2014-07-03 |
WO2014106208A1 (en) | 2014-07-03 |
JP2017105855A (ja) | 2017-06-15 |
MY172519A (en) | 2019-11-28 |
ZA201504109B (en) | 2019-10-30 |
CN110179995A (zh) | 2019-08-30 |
US20180021454A1 (en) | 2018-01-25 |
MX2015008503A (es) | 2016-01-22 |
JP2016505609A (ja) | 2016-02-25 |
CN104936622A (zh) | 2015-09-23 |
CA2896571C (en) | 2017-11-21 |
US20220288229A1 (en) | 2022-09-15 |
MX360098B (es) | 2018-10-22 |
AU2013369982A1 (en) | 2015-06-18 |
AU2013369982B2 (en) | 2016-11-17 |
US20200121808A1 (en) | 2020-04-23 |
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