RO86724B - Procedeu pentru prepararea unui derivat de peptida ciclica - Google Patents

Procedeu pentru prepararea unui derivat de peptida ciclica

Info

Publication number
RO86724B
RO86724B RO110960A RO11096083A RO86724B RO 86724 B RO86724 B RO 86724B RO 110960 A RO110960 A RO 110960A RO 11096083 A RO11096083 A RO 11096083A RO 86724 B RO86724 B RO 86724B
Authority
RO
Romania
Prior art keywords
nrrl
preparation
general formula
cyclic peptide
actinoplanes
Prior art date
Application number
RO110960A
Other languages
English (en)
Other versions
RO86724A (ro
Inventor
Bernard John Abbott
Manuel Debono
David Shuichi Fukuda
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of RO86724A publication Critical patent/RO86724A/ro
Publication of RO86724B publication Critical patent/RO86724B/ro

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Inventia se refera la un procedeu pentru prepararea unui derivat de peptida ciclica cu formula generala I: (vezi formula) procedeu, ce consta în faptul ca daca se doreste protectia uneia sau a mai multor grupe de protectie amino existente în compusul cu formula generala I în sine cunoscuta, dupa care produsul protejat este dezacilat prin incubarea într-un mediu de cultura continînd un microorganism ales dintre Actinoplanes utahansis NRRL 12052 Streptosporangium roseum varietatea hollandensis NRRL 12064, Actinoplanes missouriensis NRRL 12053, Actinoplanes species NRRL 12065 si NRRL 8122, dupa care se doreste grupele de protectie aminoexistente pot fi îndepartate din compusul cu formula generala I.
RO110960A 1982-05-21 1983-05-16 Procedeu pentru prepararea unui derivat de peptida ciclica RO86724B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38049782A 1982-05-21 1982-05-21

Publications (2)

Publication Number Publication Date
RO86724A RO86724A (ro) 1985-04-17
RO86724B true RO86724B (ro) 1985-05-01

Family

ID=23501396

Family Applications (1)

Application Number Title Priority Date Filing Date
RO110960A RO86724B (ro) 1982-05-21 1983-05-16 Procedeu pentru prepararea unui derivat de peptida ciclica

Country Status (16)

Country Link
KR (1) KR860001285B1 (ro)
AR (1) AR241943A1 (ro)
AT (1) AT381103B (ro)
CA (1) CA1200777A (ro)
DD (1) DD210285A5 (ro)
DK (1) DK221083A (ro)
EG (1) EG16043A (ro)
ES (2) ES8502731A1 (ro)
FI (1) FI79545C (ro)
GR (1) GR78567B (ro)
HU (1) HU195839B (ro)
PH (1) PH22066A (ro)
PL (1) PL242099A1 (ro)
PT (1) PT76700B (ro)
RO (1) RO86724B (ro)
ZA (1) ZA833451B (ro)

Also Published As

Publication number Publication date
ZA833451B (en) 1984-12-24
ES535958A0 (es) 1985-06-16
AT381103B (de) 1986-08-25
FI831748L (fi) 1983-11-22
KR860001285B1 (ko) 1986-09-05
ATA178283A (de) 1986-01-15
PT76700B (en) 1986-03-27
PH22066A (en) 1988-05-20
ES522560A0 (es) 1985-01-16
DK221083A (da) 1983-11-22
RO86724A (ro) 1985-04-17
ES8506097A1 (es) 1985-06-16
CA1200777A (en) 1986-02-18
DK221083D0 (da) 1983-05-18
PL242099A1 (en) 1984-07-30
FI831748A0 (fi) 1983-05-18
FI79545B (fi) 1989-09-29
HU195839B (en) 1988-07-28
DD210285A5 (de) 1984-06-06
PT76700A (en) 1983-06-01
KR840005075A (ko) 1984-11-03
ES8502731A1 (es) 1985-01-16
AR241943A1 (es) 1993-01-29
GR78567B (ro) 1984-09-27
FI79545C (fi) 1990-01-10
EG16043A (en) 1987-05-30

Similar Documents

Publication Publication Date Title
DE69628559D1 (en) Carbonyl-piperaznyl und piperidinyl derivate zur hemmung farnesyl protein transferase
MY107056A (en) Lactam free cyclic amino acids.
ATE90107T1 (de) Peptide mit collagenase hemmender wirkung.
IL77750A (en) Insecticidal compositions containing oxazines and/or thiazines,some such novel compounds and process for their preparation
ES485359A1 (es) Procedimiento para la reaccion por adicion de hidrogeno uni-do a si
CO4810230A1 (es) Nuevos derivados del 19-nor-pregneno
DK670389D0 (da) Benzyliden-azolylmethylcycloalkan- eller -alken-derivater og deres anvendelse til plantebeskyttelse
ATE124421T1 (de) Verfahren zur wachstumshemmung von stammzellen.
MY131303A (en) Sulfonamido-alkyl-carboxamido-methyl-piperidine and morpholine derivatives
YU234790A (sh) Posotupak za dobijanje glikopeptidnih derivata i glikopeptidni derivati
CA2266015A1 (en) Tricyclic antitumor compounds being farnesyl protein transferase inhibitors
DE69103413D1 (de) Verfahren zur enantioselektiven herstellung von phenylisoserinderivaten.
ATE57386T1 (de) Verfahren zur herstellung von butylen-polymeren mit molekulargewicht von 400 bis 5000.
ATE114658T1 (de) Piperaziniocephalosporine.
HUP0001164A2 (hu) PF1022-ciklodepszipeptid-származékok
ATE108178T1 (de) Dipeptide, verwendbar als pflanzenwachstumsregulatoren.
MX9708452A (es) Inhibidores de sialidasa bacteriana y metodos para fabricar y usar la misma.
HUP0203855A2 (hu) Szubsztituált piperazinszármazékok mint MTP inhibitorok, ezeket tartalmazó gyógyszerkészítmények és eljárás az előállításaikra
RO86724B (ro) Procedeu pentru prepararea unui derivat de peptida ciclica
ES8600261A1 (es) Un compuesto fenoxi
HUP9801057A2 (hu) Piridil-tiazol-származékok és mikroorganizmusok elleni növényvédő szerként történő alkalmazásuk
GB8905768D0 (en) Compositions of matter
ID22156A (id) Turunan substitusi benzosikloheptapiridina yang berguna untuk menghambat fernesil protein transferase
IL133414A0 (en) Benzo (5, 6) cycloheptapyridine cyclic ureas and lactams useful as farnesyl protein transferase inhibitors
SE8306112L (sv) Biologiskt aktiva peptider