RO75964A - Procedeu pentru prepararea unei forme cristaline anhidre a 7-(d-2-hidroxi-2-fenilacetamido)-3-(1-metil-1h-tetrazol-5-iltiometil)-3-cefem-4-carboxilatului de sodiu - Google Patents

Procedeu pentru prepararea unei forme cristaline anhidre a 7-(d-2-hidroxi-2-fenilacetamido)-3-(1-metil-1h-tetrazol-5-iltiometil)-3-cefem-4-carboxilatului de sodiu

Info

Publication number
RO75964A
RO75964A RO7696125A RO9612576A RO75964A RO 75964 A RO75964 A RO 75964A RO 7696125 A RO7696125 A RO 7696125A RO 9612576 A RO9612576 A RO 9612576A RO 75964 A RO75964 A RO 75964A
Authority
RO
Romania
Prior art keywords
phenylacetmido
ilthiomethyl
cephem
tetrazole
hydroxy
Prior art date
Application number
RO7696125A
Other languages
English (en)
French (fr)
Inventor
Kuo Shang Yang
Original Assignee
Eli Lilly And Co,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us
Publication of RO75964A publication Critical patent/RO75964A/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RO7696125A 1975-12-22 1976-12-18 Procedeu pentru prepararea unei forme cristaline anhidre a 7-(d-2-hidroxi-2-fenilacetamido)-3-(1-metil-1h-tetrazol-5-iltiometil)-3-cefem-4-carboxilatului de sodiu RO75964A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/642,922 US4054738A (en) 1975-12-22 1975-12-22 Sodium cefamandole crystalline forms

Publications (1)

Publication Number Publication Date
RO75964A true RO75964A (ro) 1981-02-28

Family

ID=24578600

Family Applications (3)

Application Number Title Priority Date Filing Date
RO7696124A RO75963A (ro) 1975-12-22 1976-12-18 Procedeu pentru prepararea unei forme cristaline anhidre a 7-(d-2-hidroxi-2-fenilacetamida)-3-(1-metil-1h-tetrazol-5-iltiometil)-3-cefem-4-carboxilatului de sodiu
RO7696125A RO75964A (ro) 1975-12-22 1976-12-18 Procedeu pentru prepararea unei forme cristaline anhidre a 7-(d-2-hidroxi-2-fenilacetamido)-3-(1-metil-1h-tetrazol-5-iltiometil)-3-cefem-4-carboxilatului de sodiu
RO7688777A RO69709A (ro) 1975-12-22 1976-12-18 Procedeu pentru prepararea unei forme cristaline metanolate a 7-(d-2-hidroxi-2-fenilacetamido)-3-(1-metil-1h-tetrazol-5-iltiometil)-3-cefem-4-carboxilatului de sodiu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RO7696124A RO75963A (ro) 1975-12-22 1976-12-18 Procedeu pentru prepararea unei forme cristaline anhidre a 7-(d-2-hidroxi-2-fenilacetamida)-3-(1-metil-1h-tetrazol-5-iltiometil)-3-cefem-4-carboxilatului de sodiu

Family Applications After (1)

Application Number Title Priority Date Filing Date
RO7688777A RO69709A (ro) 1975-12-22 1976-12-18 Procedeu pentru prepararea unei forme cristaline metanolate a 7-(d-2-hidroxi-2-fenilacetamido)-3-(1-metil-1h-tetrazol-5-iltiometil)-3-cefem-4-carboxilatului de sodiu

Country Status (31)

Country Link
US (1) US4054738A (ro)
JP (2) JPS5282714A (ro)
AR (1) AR213300A1 (ro)
AT (2) AT348678B (ro)
AU (1) AU505924B2 (ro)
BE (1) BE849415A (ro)
CA (1) CA1080696A (ro)
CH (1) CH628348A5 (ro)
CS (1) CS195746B2 (ro)
DD (1) DD128727A5 (ro)
DE (1) DE2654647C2 (ro)
DK (1) DK153156C (ro)
FI (1) FI66008C (ro)
FR (3) FR2361898A1 (ro)
GB (1) GB1565854A (ro)
GR (1) GR65891B (ro)
HU (1) HU172474B (ro)
IL (3) IL50977A (ro)
LU (1) LU76435A1 (ro)
MX (1) MX3840E (ro)
NL (1) NL187483C (ro)
NO (1) NO148887C (ro)
NZ (1) NZ182694A (ro)
OA (1) OA05518A (ro)
PH (1) PH12191A (ro)
PL (1) PL102739B1 (ro)
PT (1) PT65955B (ro)
RO (3) RO75963A (ro)
SE (3) SE424730B (ro)
SU (3) SU637087A3 (ro)
ZA (1) ZA766957B (ro)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168376A (en) * 1978-06-05 1979-09-18 Eli Lilly And Company Process for crystalline sodium cefamandole
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
DE3313816A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
DE3313818A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
CA1242699A (en) * 1985-02-01 1988-10-04 Bristol-Myers Company Cefbuperazone and derivatives thereof
JPH0677413B2 (ja) * 1985-05-03 1994-09-28 株式会社フジクラ 高圧直流送電用電力ケーブル
JPS629495U (ro) * 1985-07-01 1987-01-21
GB9717629D0 (en) 1997-08-21 1997-10-22 Johnson Matthey Plc Removal of residual organic solvents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496171A (en) * 1969-02-17 1970-02-17 Lilly Co Eli Process for improving the physical and chemical properties of cephaloglycin
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
US3692781A (en) * 1971-02-26 1972-09-19 Glaxo Lab Ltd Recovery of pure cephalexin from acidic reaction mixtures
US3819620A (en) * 1972-06-01 1974-06-25 Squibb & Sons Inc 7-(d-alpha-amino-1,4-cyclohexadien-1-ylacet-amido)desacetoxycephalosporanic acid dihydrate
US3862186A (en) * 1972-12-15 1975-01-21 Bristol Myers Co Process for the production of cephalexin monohydrate
US3928592A (en) * 1974-02-22 1975-12-23 Lilly Co Eli Antibiotic pharmaceutical compositions

Also Published As

Publication number Publication date
FR2351985A1 (fr) 1977-12-16
RO75963A (ro) 1981-02-28
FR2351984B1 (ro) 1980-06-27
CA1080696A (en) 1980-07-01
HU172474B (hu) 1978-09-28
FR2361898A1 (fr) 1978-03-17
AU505924B2 (en) 1979-12-06
JPS6183189A (ja) 1986-04-26
AU2001376A (en) 1978-06-01
CS195746B2 (en) 1980-02-29
IL57387A0 (en) 1979-09-30
NO148887C (no) 1984-01-04
MX3840E (es) 1981-08-11
PL102739B1 (pl) 1979-04-30
CH628348A5 (de) 1982-02-26
JPS5282714A (en) 1977-07-11
NO148887B (no) 1983-09-26
DE2654647A1 (de) 1977-06-30
RO69709A (ro) 1980-04-15
DK153156B (da) 1988-06-20
US4054738A (en) 1977-10-18
FR2361898B1 (ro) 1980-03-14
FI763682A (ro) 1977-06-23
DK153156C (da) 1989-02-20
FI66008C (fi) 1984-08-10
SU637087A3 (ru) 1978-12-05
NO764222L (ro) 1977-06-23
PT65955B (en) 1978-06-15
JPS61351B2 (ro) 1986-01-08
AT348678B (de) 1979-02-26
DK575576A (da) 1977-06-23
NL7614233A (nl) 1977-06-24
FI66008B (fi) 1984-04-30
IL50977A0 (en) 1977-01-31
SE8201701L (sv) 1982-03-17
ATA948976A (de) 1978-07-15
AT349148B (de) 1979-03-26
GB1565854A (en) 1980-04-23
DE2654647C2 (de) 1982-06-24
SE441096B (sv) 1985-09-09
FR2351985B1 (ro) 1980-06-27
DD128727A5 (de) 1977-12-07
FR2351984A1 (fr) 1977-12-16
ATA217578A (de) 1978-08-15
LU76435A1 (ro) 1977-06-10
PH12191A (en) 1978-11-21
NZ182694A (en) 1978-09-25
NL187483B (nl) 1991-05-16
GR65891B (ro) 1980-12-01
AR213300A1 (es) 1979-01-15
IL57386A0 (en) 1979-09-30
SU671732A3 (ru) 1979-06-30
JPS624393B2 (ro) 1987-01-30
BE849415A (fr) 1977-06-15
IL50977A (en) 1980-02-29
OA05518A (fr) 1981-04-30
SE7614401L (sv) 1977-06-23
ZA766957B (en) 1978-06-28
NL187483C (nl) 1991-10-16
PT65955A (en) 1977-01-01
SE424730B (sv) 1982-08-09
SU1018585A3 (ru) 1983-05-15
SE443564B (sv) 1986-03-03
SE8201702L (sv) 1982-03-17

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