ATA217578A - Verfahren zur herstellung des neuen kristallinen monohydrates von natrium-7-(d-2- hydroxy-2-phenylacetamido)-3-(1-methyl-1h- tetrazol-5-yl-thiomethyl)-3-cephem-4- carboxylat - Google Patents
Verfahren zur herstellung des neuen kristallinen monohydrates von natrium-7-(d-2- hydroxy-2-phenylacetamido)-3-(1-methyl-1h- tetrazol-5-yl-thiomethyl)-3-cephem-4- carboxylatInfo
- Publication number
- ATA217578A ATA217578A AT782175A AT217578A ATA217578A AT A217578 A ATA217578 A AT A217578A AT 782175 A AT782175 A AT 782175A AT 217578 A AT217578 A AT 217578A AT A217578 A ATA217578 A AT A217578A
- Authority
- AT
- Austria
- Prior art keywords
- phenylacetamido
- cephem
- thiomethyl
- tetrazol
- carboxylate
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000004682 monohydrates Chemical class 0.000 title 1
- OJMNTWPPFNMOCJ-MDJBORCBSA-M sodium (6R)-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Chemical compound O[C@@H](C(=O)NC1[C@@H]2N(C(=C(CS2)CSC2=NN=NN2C)C(=O)[O-])C1=O)C1=CC=CC=C1.[Na+] OJMNTWPPFNMOCJ-MDJBORCBSA-M 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/642,922 US4054738A (en) | 1975-12-22 | 1975-12-22 | Sodium cefamandole crystalline forms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA217578A true ATA217578A (de) | 1978-08-15 |
| AT349148B AT349148B (de) | 1979-03-26 |
Family
ID=24578600
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT948976A AT348678B (de) | 1975-12-22 | 1976-12-21 | Verfahren zur herstellung des neuen kristallinen anhydrats von natrium-7-(d-2-hydroxy-2-phenylacetamido)-3-(1- methyl-1h-tetrazol-5-yl-thiomethyl)-3-cephem-4- carboxylat |
| AT217578A AT349148B (de) | 1975-12-22 | 1976-12-21 | Verfahren zur herstellung des neuen kristallinen monohydrates von natrium-7-(d-2- hydroxy-2-phenylacetamido)-3-(1-methyl-1h- tetrazol-5-yl-thiomethyl)-3-cephem-4- carboxylat |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT948976A AT348678B (de) | 1975-12-22 | 1976-12-21 | Verfahren zur herstellung des neuen kristallinen anhydrats von natrium-7-(d-2-hydroxy-2-phenylacetamido)-3-(1- methyl-1h-tetrazol-5-yl-thiomethyl)-3-cephem-4- carboxylat |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US4054738A (de) |
| JP (2) | JPS5282714A (de) |
| AR (1) | AR213300A1 (de) |
| AT (2) | AT348678B (de) |
| AU (1) | AU505924B2 (de) |
| BE (1) | BE849415A (de) |
| CA (1) | CA1080696A (de) |
| CH (1) | CH628348A5 (de) |
| CS (1) | CS195746B2 (de) |
| DD (1) | DD128727A5 (de) |
| DE (1) | DE2654647C2 (de) |
| DK (1) | DK153156C (de) |
| FI (1) | FI66008C (de) |
| FR (3) | FR2361898A1 (de) |
| GB (1) | GB1565854A (de) |
| GR (1) | GR65891B (de) |
| HU (1) | HU172474B (de) |
| IL (3) | IL50977A (de) |
| LU (1) | LU76435A1 (de) |
| MX (1) | MX3840E (de) |
| NL (1) | NL187483C (de) |
| NO (1) | NO148887C (de) |
| NZ (1) | NZ182694A (de) |
| OA (1) | OA05518A (de) |
| PH (1) | PH12191A (de) |
| PL (1) | PL102739B1 (de) |
| PT (1) | PT65955B (de) |
| RO (3) | RO75964A (de) |
| SE (3) | SE424730B (de) |
| SU (3) | SU637087A3 (de) |
| ZA (1) | ZA766957B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4168376A (en) * | 1978-06-05 | 1979-09-18 | Eli Lilly And Company | Process for crystalline sodium cefamandole |
| US4237279A (en) * | 1979-07-27 | 1980-12-02 | Eli Lilly And Company | Crystalline 3-hydroxycephalosporin solvates |
| DE3313816A1 (de) * | 1983-04-16 | 1984-10-18 | Hoechst Ag, 6230 Frankfurt | Neue kristallmodifikation von ceftazidim |
| DE3313818A1 (de) * | 1983-04-16 | 1984-10-18 | Hoechst Ag, 6230 Frankfurt | Neue kristallmodifikation von ceftazidim |
| CA1242699A (en) * | 1985-02-01 | 1988-10-04 | Bristol-Myers Company | Cefbuperazone and derivatives thereof |
| JPH0677412B2 (ja) * | 1985-05-03 | 1994-09-28 | 株式会社フジクラ | 高圧直流送電用電力ケーブル |
| JPS629495U (de) * | 1985-07-01 | 1987-01-21 | ||
| GB9717629D0 (en) | 1997-08-21 | 1997-10-22 | Johnson Matthey Plc | Removal of residual organic solvents |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3496171A (en) * | 1969-02-17 | 1970-02-17 | Lilly Co Eli | Process for improving the physical and chemical properties of cephaloglycin |
| US3641021A (en) * | 1969-04-18 | 1972-02-08 | Lilly Co Eli | 3 7-(ring-substituted) cephalosporin compounds |
| US3692781A (en) * | 1971-02-26 | 1972-09-19 | Glaxo Lab Ltd | Recovery of pure cephalexin from acidic reaction mixtures |
| US3819620A (en) * | 1972-06-01 | 1974-06-25 | Squibb & Sons Inc | 7-(d-alpha-amino-1,4-cyclohexadien-1-ylacet-amido)desacetoxycephalosporanic acid dihydrate |
| US3862186A (en) * | 1972-12-15 | 1975-01-21 | Bristol Myers Co | Process for the production of cephalexin monohydrate |
| US3928592A (en) * | 1974-02-22 | 1975-12-23 | Lilly Co Eli | Antibiotic pharmaceutical compositions |
-
1975
- 1975-12-22 US US05/642,922 patent/US4054738A/en not_active Expired - Lifetime
-
1976
- 1976-11-18 GR GR52212A patent/GR65891B/el unknown
- 1976-11-19 CA CA266,112A patent/CA1080696A/en not_active Expired
- 1976-11-22 ZA ZA00766957A patent/ZA766957B/xx unknown
- 1976-11-23 NZ NZ182694A patent/NZ182694A/xx unknown
- 1976-11-24 IL IL50977A patent/IL50977A/xx unknown
- 1976-11-25 AU AU20013/76A patent/AU505924B2/en not_active Expired
- 1976-12-02 DE DE2654647A patent/DE2654647C2/de not_active Expired
- 1976-12-06 MX MX765190U patent/MX3840E/es unknown
- 1976-12-08 CH CH1543176A patent/CH628348A5/de not_active IP Right Cessation
- 1976-12-13 PT PT65955A patent/PT65955B/pt unknown
- 1976-12-13 NO NO764222A patent/NO148887C/no unknown
- 1976-12-14 AR AR265847A patent/AR213300A1/es active
- 1976-12-15 BE BE1007825A patent/BE849415A/xx not_active IP Right Cessation
- 1976-12-15 GB GB52235/76A patent/GB1565854A/en not_active Expired
- 1976-12-15 JP JP15143776A patent/JPS5282714A/ja active Granted
- 1976-12-15 FR FR7637750A patent/FR2361898A1/fr active Granted
- 1976-12-16 CS CS768302A patent/CS195746B2/cs unknown
- 1976-12-17 PH PH19260A patent/PH12191A/en unknown
- 1976-12-18 RO RO7696125A patent/RO75964A/ro unknown
- 1976-12-18 RO RO7696124A patent/RO75963A/ro unknown
- 1976-12-18 RO RO7688777A patent/RO69709A/ro unknown
- 1976-12-20 LU LU76435A patent/LU76435A1/xx unknown
- 1976-12-21 SE SE7614401A patent/SE424730B/xx not_active IP Right Cessation
- 1976-12-21 HU HU76EI00000720A patent/HU172474B/hu unknown
- 1976-12-21 NL NLAANVRAGE7614233,A patent/NL187483C/xx not_active IP Right Cessation
- 1976-12-21 OA OA56020A patent/OA05518A/xx unknown
- 1976-12-21 AT AT948976A patent/AT348678B/de active
- 1976-12-21 AT AT217578A patent/AT349148B/de not_active IP Right Cessation
- 1976-12-21 DK DK575576A patent/DK153156C/da not_active IP Right Cessation
- 1976-12-22 FI FI763682A patent/FI66008C/fi not_active IP Right Cessation
- 1976-12-22 PL PL1976194617A patent/PL102739B1/pl unknown
- 1976-12-22 DD DD7600196537A patent/DD128727A5/de unknown
- 1976-12-22 SU SU762433502A patent/SU637087A3/ru active
-
1977
- 1977-05-20 FR FR7715577A patent/FR2351985A1/fr active Granted
- 1977-05-20 FR FR7715576A patent/FR2351984A1/fr active Granted
- 1977-11-17 SU SU772541708A patent/SU671732A3/ru active
- 1977-12-21 SU SU772556949A patent/SU1018585A3/ru active
-
1979
- 1979-05-23 IL IL57386A patent/IL57386A0/xx not_active IP Right Cessation
- 1979-05-23 IL IL57387A patent/IL57387A0/xx not_active IP Right Cessation
-
1982
- 1982-03-17 SE SE8201702A patent/SE441096B/sv not_active IP Right Cessation
- 1982-03-17 SE SE8201701A patent/SE443564B/sv not_active IP Right Cessation
-
1985
- 1985-05-24 JP JP60113022A patent/JPS6183189A/ja active Granted
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DD138423A5 (de) | Verfahren zur herstellung von cephemderivaten | |
| AT345795B (de) | Verfahren zur herstellung von neuen phenylalkancarbonsaeure-derivaten | |
| AT350722B (de) | Verfahren zur herstellung von neuen kanamycin- derivaten | |
| ATA217578A (de) | Verfahren zur herstellung des neuen kristallinen monohydrates von natrium-7-(d-2- hydroxy-2-phenylacetamido)-3-(1-methyl-1h- tetrazol-5-yl-thiomethyl)-3-cephem-4- carboxylat | |
| ATA126476A (de) | Verfahren zur herstellung von neuen 3-acyloxymethyl-cephem-verbindungen | |
| AT349143B (de) | Verfahren zur herstellung von neuen derivaten der 3-carbamoyloxy-methyl-7-(amino-4- thiazolyl-acetamido)-cephalosporansaeure | |
| AT347963B (de) | Verfahren zur herstellung von neuen 4- halogenazetidinon-1-essigsaeurederivaten | |
| ATA851176A (de) | Verfahren zur herstellung des neuen trinatriumsalzes von 2-carboxymethyloxymalonsauremonohydrat | |
| DD132344A5 (de) | Verfahren zur herstellung von beta-lactam-antibiotika | |
| AT353278B (de) | Verfahren zur herstellung von neuen azetidin- derivaten | |
| AT341674B (de) | Verfahren zur herstellung von 7- (d-2-amino-3-phenylacetamido)-3-methyl-3-cephem-4-carbonsaure | |
| ATA52878A (de) | Verfahren zur herstellung des neuen lysinsalzes der alpha-methyl-(2-isopropyl-indan-5-yl)- essigsaeure | |
| AT349149B (de) | Verfahren zur herstellung des neuen kristallinen methanolats von natrium-7-(d-2- hydroxy-2-phenylacetamido)-3-(1-methyl-1h- tetrazol-5-yl-thiomethyl)-3-cephem-4- carboxylat | |
| ATA69676A (de) | Verfahren zur herstellung von neuen bis-triarylphosphoniumsalzen | |
| AT349476B (de) | Verfahren zur herstellung von neuen phenoxy- alkancarbonsaeurederivaten von 1-cinnamyl-4- diphenylmethylpiperazin | |
| ATA716477A (de) | Verfahren zur herstellung von cephalosporin- verbindungen | |
| AT346354B (de) | Verfahren zur herstellung von neuen 2- morpholinonderivaten | |
| PT67138B (de) | Verfahren zur herstellung des magnesiumsalzes der p-chlorphenoxyisobuttersaure | |
| ATA569180A (de) | Verfahren zur herstellung von cephalosporansaeure- derivaten | |
| ATA554180A (de) | Verfahren zur herstellung von cephalosporansaeure- derivaten | |
| ATA475677A (de) | Verfahren zur herstellung von neuen phenylalkancarbonsaeure-derivaten | |
| ATA721977A (de) | Verfahren zur herstellung von neuen dipeptid- -derivaten | |
| AT347036B (de) | Verfahren zur herstellung von neuen cephalosporinderivaten | |
| AT350186B (de) | Verfahren zur herstellung von neuen cephalosporinderivaten | |
| AT340049B (de) | Verfahren zur herstellung von neuen 7-(3-alkansulfonamidophenyl-d-glycinamido)-3-methyl-3-cephem-4-carbonsauren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| UEP | Publication of translation of european patent specification |