US4464467A
(en)
*
|
1982-07-26 |
1984-08-07 |
Bristol-Myers Company |
Antitumor antibiotics produced by new streptomyces
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
GB9818732D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
DE69930328T2
(de)
|
1998-08-27 |
2006-12-14 |
Spirogen Ltd., Ryde |
Dimere Pyrrolobenzodiazepine
|
US6909006B1
(en)
|
1999-08-27 |
2005-06-21 |
Spirogen Limited |
Cyclopropylindole derivatives
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
CA2558195C
(en)
|
2004-03-01 |
2012-11-06 |
Spirogen Limited |
11-hydroxy-5h-pyrrolo[2,1-c][1,4]benzodiazepin-5-one derivatives as key intermediates for the preparation of c2 substituted pyrrolobenzodiazepines
|
GB0404577D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
JP5166861B2
(ja)
|
2004-03-09 |
2013-03-21 |
スピロゲン リミティッド |
ピロロベンゾジアゼピン
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
EP2789622B1
(en)
|
2010-04-15 |
2017-03-01 |
MedImmune Limited |
Pyrrolobenzodiazepines used to treat proliferative diseases
|
KR101671360B1
(ko)
|
2010-04-15 |
2016-11-01 |
시애틀 지네틱스, 인크. |
표적화된 피롤로벤조디아제핀 접합체
|
CA2849039C
(en)
|
2011-09-20 |
2018-09-18 |
Spirogen Sarl |
Pyrrolobenzodiazepines as unsymmetrical dimeric pbd compounds for inclusion in targeted conjugates
|
EP2751111B1
(en)
|
2011-10-14 |
2017-04-26 |
MedImmune Limited |
Asymmetrical bis-(5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one) derivatives for the treatment of proliferative or autoimmune diseases
|
JP6393617B2
(ja)
|
2011-10-14 |
2018-09-19 |
シアトル ジェネティクス,インコーポレーテッド |
ピロロベンゾジアゼピンおよび標的コンジュゲート
|
EP3309162A1
(en)
|
2011-10-14 |
2018-04-18 |
Seattle Genetics, Inc. |
Targeted conjugates of pyrrolobenzodiazepines
|
CA2850096C
(en)
|
2011-10-14 |
2018-07-03 |
Spirogen Sarl |
Synthesis method and intermediates useful in the preparation of pyrrolobenzodiazepines
|
BR112014008981A2
(pt)
|
2011-10-14 |
2017-05-02 |
Spirogen Sàrl |
pirrolobenzodiazepinas
|
CN105102068B
(zh)
|
2012-10-12 |
2018-06-01 |
Adc疗法责任有限公司 |
吡咯并苯并二氮杂卓-抗体结合物
|
DK2906298T3
(en)
|
2012-10-12 |
2018-12-17 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
EP2906250B1
(en)
|
2012-10-12 |
2018-05-30 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-anti-psma antibody conjugates
|
WO2014057122A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-anti-cd22 antibody conjugates
|
MX364326B
(es)
|
2012-10-12 |
2019-04-23 |
Medimmune Ltd |
Conjugados del anticuerpo pirrolobenzodiazepina - anti-psma.
|
ES2660029T3
(es)
|
2012-10-12 |
2018-03-20 |
Medimmune Limited |
Conjugados de anticuerpo-pirrolobenzodiazepinas
|
KR20150083994A
(ko)
|
2012-10-12 |
2015-07-21 |
스피로즌 살 |
피롤로벤조디아제핀 및 그의 컨주게이트
|
AU2013328673B2
(en)
|
2012-10-12 |
2017-07-13 |
Medimmune Limited |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
CN104837502B
(zh)
|
2012-10-12 |
2018-08-10 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓及其结合物
|
WO2015052534A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
WO2015052535A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
WO2015052532A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
US10780096B2
(en)
|
2014-11-25 |
2020-09-22 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
RS61795B1
(sr)
|
2017-02-08 |
2021-06-30 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin antitela
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
JP2020517609A
(ja)
|
2017-04-18 |
2020-06-18 |
メディミューン リミテッド |
ピロロベンゾジアゼピン複合体
|
BR112019021880A2
(pt)
|
2017-04-20 |
2020-06-02 |
Adc Therapeutics Sa |
Terapia de combinação com conjugado anticorpo anti-axl-droga
|
WO2018229222A1
(en)
|
2017-06-14 |
2018-12-20 |
Adc Therapeutics Sa |
Dosage regimes for the administration of an anti-cd19 adc
|
WO2019034764A1
(en)
|
2017-08-18 |
2019-02-21 |
Medimmune Limited |
CONJUGATES OF PYRROLOBENZODIAZEPINE
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|