RO121891B1 - Compoziţie farmaceutică pentru profilaxia şi tratamentul dereglărilor metabolismului calciului şi procedeu de preparare - Google Patents

Compoziţie farmaceutică pentru profilaxia şi tratamentul dereglărilor metabolismului calciului şi procedeu de preparare Download PDF

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Publication number
RO121891B1
RO121891B1 ROA200100780A RO200100780A RO121891B1 RO 121891 B1 RO121891 B1 RO 121891B1 RO A200100780 A ROA200100780 A RO A200100780A RO 200100780 A RO200100780 A RO 200100780A RO 121891 B1 RO121891 B1 RO 121891B1
Authority
RO
Romania
Prior art keywords
pharmaceutical composition
clodronate
atomized
disodium
silicon dioxide
Prior art date
Application number
ROA200100780A
Other languages
English (en)
Romanian (ro)
Inventor
Lelia Georgeta Lazăr
Tincuţa Dinu
Cornelia Stancu
Irinel Badea
Maria Rotaru
Veronica Drăghici
Original Assignee
Sindan S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sindan S.R.L. filed Critical Sindan S.R.L.
Priority to ROA200100780A priority Critical patent/RO121891B1/ro
Priority to PCT/RO2002/000017 priority patent/WO2003004008A2/en
Priority to AU2002326251A priority patent/AU2002326251A1/en
Priority to EP02760933A priority patent/EP1408934A2/de
Publication of RO121891B1 publication Critical patent/RO121891B1/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ROA200100780A 2001-07-04 2001-07-04 Compoziţie farmaceutică pentru profilaxia şi tratamentul dereglărilor metabolismului calciului şi procedeu de preparare RO121891B1 (ro)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ROA200100780A RO121891B1 (ro) 2001-07-04 2001-07-04 Compoziţie farmaceutică pentru profilaxia şi tratamentul dereglărilor metabolismului calciului şi procedeu de preparare
PCT/RO2002/000017 WO2003004008A2 (en) 2001-07-04 2002-07-02 Pharmaceutical composition for prophylaxis and treatment of calcium metabolism disorders comprising clodronate in combination with glyceryl palmitostearate
AU2002326251A AU2002326251A1 (en) 2001-07-04 2002-07-02 Pharmaceutical composition for prophylaxis and treatment of calcium metabolism disorders comprising clodronate in combination with glyceryl palmitostearate
EP02760933A EP1408934A2 (de) 2001-07-04 2002-07-02 Pharmazeutische zusammensetzung zur prophylaxe und behandlung von calcium metabolismus störungen enthaltend clodronat in kombination mit glyceryl palmitostearat

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ROA200100780A RO121891B1 (ro) 2001-07-04 2001-07-04 Compoziţie farmaceutică pentru profilaxia şi tratamentul dereglărilor metabolismului calciului şi procedeu de preparare

Publications (1)

Publication Number Publication Date
RO121891B1 true RO121891B1 (ro) 2008-07-30

Family

ID=20129443

Family Applications (1)

Application Number Title Priority Date Filing Date
ROA200100780A RO121891B1 (ro) 2001-07-04 2001-07-04 Compoziţie farmaceutică pentru profilaxia şi tratamentul dereglărilor metabolismului calciului şi procedeu de preparare

Country Status (4)

Country Link
EP (1) EP1408934A2 (de)
AU (1) AU2002326251A1 (de)
RO (1) RO121891B1 (de)
WO (1) WO2003004008A2 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE60711T1 (de) * 1986-12-20 1991-02-15 Boehringer Mannheim Gmbh Clodronat-haltige arzneimittel und verfahren zur herstellung derselben.
FI94926C (fi) * 1993-11-12 1995-11-27 Leiras Oy Menetelmä klodronaattivalmisteen valmistamiseksi

Also Published As

Publication number Publication date
AU2002326251A1 (en) 2003-01-21
EP1408934A2 (de) 2004-04-21
WO2003004008A2 (en) 2003-01-16
WO2003004008A3 (en) 2003-05-01

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