RO117793B1 - Derivati de acid piridoncarboxilic si compozitie farmaceutica care ii contine - Google Patents

Derivati de acid piridoncarboxilic si compozitie farmaceutica care ii contine Download PDF

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Publication number
RO117793B1
RO117793B1 RO96-02349A RO9602349A RO117793B1 RO 117793 B1 RO117793 B1 RO 117793B1 RO 9602349 A RO9602349 A RO 9602349A RO 117793 B1 RO117793 B1 RO 117793B1
Authority
RO
Romania
Prior art keywords
group
hydrogen atom
halogen atom
lower alkyl
acid
Prior art date
Application number
RO96-02349A
Other languages
English (en)
Romanian (ro)
Inventor
Kyoji Tomita
Katsumi Chiba
Shigeki Kashimoto
Koh-Ichiro Shibamori
Yasunori Tsuzuki
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of RO117793B1 publication Critical patent/RO117793B1/ro

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RO96-02349A 1994-06-14 1995-06-06 Derivati de acid piridoncarboxilic si compozitie farmaceutica care ii contine RO117793B1 (ro)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP15657894 1994-06-14
JP19792194 1994-07-28
JP30691494 1994-11-15
JP33995694 1994-12-28
JP8170595 1995-03-13
PCT/JP1995/001110 WO1995034559A1 (en) 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent

Publications (1)

Publication Number Publication Date
RO117793B1 true RO117793B1 (ro) 2002-07-30

Family

ID=27524935

Family Applications (1)

Application Number Title Priority Date Filing Date
RO96-02349A RO117793B1 (ro) 1994-06-14 1995-06-06 Derivati de acid piridoncarboxilic si compozitie farmaceutica care ii contine

Country Status (27)

Country Link
US (1) US5817669A (show.php)
EP (1) EP0787726B1 (show.php)
JP (1) JP3391796B2 (show.php)
KR (1) KR100350921B1 (show.php)
CN (1) CN1053668C (show.php)
AT (1) ATE209645T1 (show.php)
AU (1) AU679859B2 (show.php)
BR (1) BR9508037A (show.php)
CA (1) CA2192824C (show.php)
CZ (1) CZ292631B6 (show.php)
DE (1) DE69524251T2 (show.php)
DK (1) DK0787726T3 (show.php)
ES (1) ES2163512T3 (show.php)
FI (1) FI112485B (show.php)
HK (1) HK1000495A1 (show.php)
HU (1) HU220072B (show.php)
MX (1) MX9606331A (show.php)
NO (1) NO307255B1 (show.php)
NZ (1) NZ287139A (show.php)
PL (1) PL181867B1 (show.php)
PT (1) PT787726E (show.php)
RO (1) RO117793B1 (show.php)
RU (1) RU2151770C1 (show.php)
SI (1) SI0787726T1 (show.php)
SK (1) SK281341B6 (show.php)
TW (1) TW319769B (show.php)
WO (1) WO1995034559A1 (show.php)

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BRPI0413964B8 (pt) * 2003-09-10 2021-05-25 Kyorin Seiyaku Kk ácido derivado do ácido carboxílico quinolona, sua composição e agente antibacterial
DE10352979A1 (de) * 2003-11-13 2005-06-09 Merck Patent Gmbh Pyridopyrimidinone
AU2013201203C1 (en) * 2004-03-15 2015-04-23 Sumitomo Dainippon Pharma Co., Ltd. Sns-595 and methods of using the same
CN104324029A (zh) 2004-03-15 2015-02-04 逊尼希思制药公司 Sns-595及其使用方法
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AU2005293832A1 (en) * 2004-10-14 2006-04-20 F. Hoffmann-La Roche Ag Quinazolinylmethylene thiazolinones as CDK1 inhibitors
RU2420524C2 (ru) * 2005-05-19 2011-06-10 Дайити Санкио Компани, Лимитед Производные три- или тетра-замещенного-3-аминопирролидина
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
CA2619663A1 (en) * 2005-08-19 2007-02-22 Cylene Pharmaceuticals, Inc. Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof
CN104873502A (zh) * 2005-09-02 2015-09-02 逊尼希思制药公司 使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸治疗癌症的方法
AU2013219242C1 (en) * 2005-09-02 2016-09-22 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
KR20170118936A (ko) * 2005-09-02 2017-10-25 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한 (＋)-1,4-디히드로-7-［(3ｓ,4ｓ)-3-메톡시-4-(메틸아미노)-1-피롤리디닐］-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
KR20080041298A (ko) * 2005-09-02 2008-05-09 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한(＋)-1,4-디히드로-7-[(3ｓ,4ｓ)-3-메톡시-4-(메틸아미노)-1-피롤리디닐]-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
RU2428983C2 (ru) * 2005-09-02 2011-09-20 Санесис Фармасьютикалз, Инк. Способы применения (+)-1,4-дигидро-7-[(3s,4s)-3-метокси-4-(метиламино)-1-пирролидинил]-4-оксо-1-(2-тиазолил)-1,8-нафтиридин-3-карбоновой кислоты для лечения рака
US8580814B2 (en) * 2006-04-03 2013-11-12 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
TW200800983A (en) 2005-09-14 2008-01-01 Janssen Pharmaceutica Nv 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase
US7642270B2 (en) 2005-09-14 2010-01-05 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
EP1937681A1 (en) * 2005-09-14 2008-07-02 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase
CA2654876A1 (en) * 2006-06-12 2007-12-21 Sunesis Pharmaceuticals, Inc. 1-8-naphthyridine compounds for the treatment of cancer
US20100048609A1 (en) * 2006-08-01 2010-02-25 Jacobs Jeffrey W Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
SI2049109T1 (sl) 2006-08-02 2016-04-29 Sunesis Pharmaceuticals, Inc. Kombinirana uporaba(+)-1,4-dihidro-7-((3s,4s)-3-metoksi-4-(metilamino)- 1-pirolidinil)-4-okso-1-(2-tiazolil)-1,8-naftiridin-3-karboksilne kisline in citarabina (ara-c) za zdravljenje levkemije
AU2008317400B2 (en) * 2007-10-22 2014-10-02 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino) -1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3- carboxylic acid in combination therapy
EP2249831A2 (en) 2007-12-10 2010-11-17 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-ý(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl¨-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
EP2382214B1 (en) 2008-12-31 2017-07-19 Sunesis Pharmaceuticals, Inc. Method of preparing (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
NZ594829A (en) 2009-02-27 2013-09-27 Sunesis Pharmaceuticals Inc Methods of using sns-595 for treatment of cancer subjects with reduced brca2 activity
UA110465C2 (en) 2009-09-04 2016-01-12 Sunesis Pharmaceutecals Inc Stable sns-595 composition
US8470817B2 (en) * 2009-10-26 2013-06-25 Sunesis Pharmaceuticals, Inc. Compounds and methods for treatment of cancer
SG194902A1 (en) 2011-05-13 2013-12-30 Array Biopharma Inc Pyrrolidinyl urea and pyrrolidinyl thiourea compounds as trka kinase inhibitors
CN103497186B (zh) * 2013-09-24 2015-02-25 浙江司太立制药股份有限公司 含有烷氧亚氨基取代的萘啶酮羧酸衍生物及其制备方法
ES2988457T3 (es) * 2017-03-24 2024-11-20 Wakunaga Pharma Co Ltd Derivado novedoso del ácido piridona carboxílico o sal del mismo

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Also Published As

Publication number Publication date
DE69524251T2 (de) 2002-07-11
EP0787726A1 (en) 1997-08-06
EP0787726B1 (en) 2001-11-28
PL181867B1 (pl) 2001-09-28
EP0787726A4 (show.php) 1997-08-06
HUT75777A (en) 1997-05-28
CN1158614A (zh) 1997-09-03
CA2192824C (en) 2006-11-07
ATE209645T1 (de) 2001-12-15
BR9508037A (pt) 1997-09-16
HU220072B (hu) 2001-10-28
US5817669A (en) 1998-10-06
NO965305D0 (no) 1996-12-11
SI0787726T1 (en) 2002-04-30
FI965020A7 (fi) 1996-12-16
NO965305L (no) 1997-02-04
FI965020A0 (fi) 1996-12-13
WO1995034559A1 (en) 1995-12-21
HK1000495A1 (en) 2002-07-19
AU2576795A (en) 1996-01-05
CZ364396A3 (en) 1997-06-11
FI112485B (fi) 2003-12-15
DE69524251D1 (de) 2002-01-10
SK157496A3 (en) 1997-08-06
CZ292631B6 (cs) 2003-11-12
ES2163512T3 (es) 2002-02-01
CA2192824A1 (en) 1995-12-21
DK0787726T3 (da) 2002-02-11
PL317726A1 (en) 1997-04-28
NZ287139A (en) 1997-07-27
SK281341B6 (sk) 2001-02-12
NO307255B1 (no) 2000-03-06
PT787726E (pt) 2002-04-29
KR100350921B1 (ko) 2002-11-18
HU9603455D0 (en) 1997-02-28
MX9606331A (es) 1997-03-29
JP3391796B2 (ja) 2003-03-31
CN1053668C (zh) 2000-06-21
TW319769B (show.php) 1997-11-11
AU679859B2 (en) 1997-07-10
RU2151770C1 (ru) 2000-06-27

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