PT99658A - Processo para a preparacao de 7-{3-(1,1-dialquil-metil-1-amino-1-pirrolidinil}-quinolonas e naftiridonas e de composicoes farmaceuticas anti-bacterianas que os contem - Google Patents
Processo para a preparacao de 7-{3-(1,1-dialquil-metil-1-amino-1-pirrolidinil}-quinolonas e naftiridonas e de composicoes farmaceuticas anti-bacterianas que os contemInfo
- Publication number
- PT99658A PT99658A PT99658A PT9965891A PT99658A PT 99658 A PT99658 A PT 99658A PT 99658 A PT99658 A PT 99658A PT 9965891 A PT9965891 A PT 9965891A PT 99658 A PT99658 A PT 99658A
- Authority
- PT
- Portugal
- Prior art keywords
- quinolones
- pyrrolidinyl
- amino
- pharmaceutical compositions
- naftiridones
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 150000007660 quinolones Chemical class 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/621,101 US5072001A (en) | 1990-11-30 | 1990-11-30 | Certain optically active substituted 3-pyrraidine acetic acid derivatives useful as intermediates |
| US07/730,362 US5157128A (en) | 1990-11-30 | 1991-07-15 | Certain optically active substituted α,α-dialkyl-pyrrolidine-3-methamines useful as intermediates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT99658A true PT99658A (pt) | 1992-10-30 |
| PT99658B PT99658B (pt) | 1999-05-31 |
Family
ID=27088852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99658A PT99658B (pt) | 1990-11-30 | 1991-11-29 | Processo para a preparacao de 7-{3-(1,1-dialquil-metil-1-amino-1-pirrolidinil}-quinolonas e naftiridonas e de composicoes farmaceuticas anti-bacterianas que os contem |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US5157128A (pt) |
| EP (1) | EP0559752B1 (pt) |
| JP (2) | JP2582515B2 (pt) |
| AT (1) | ATE162789T1 (pt) |
| AU (1) | AU643107B2 (pt) |
| CA (2) | CA2095361C (pt) |
| DE (1) | DE69128838T2 (pt) |
| DK (1) | DK0559752T3 (pt) |
| ES (1) | ES2113938T3 (pt) |
| GR (1) | GR3026428T3 (pt) |
| IE (1) | IE61722B1 (pt) |
| NZ (2) | NZ240783A (pt) |
| PT (1) | PT99658B (pt) |
| WO (1) | WO1992009597A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU649893B1 (en) * | 1991-11-25 | 1994-06-02 | Warner-Lambert Company | Antibacterial agents |
| ES2137942T3 (es) * | 1990-11-30 | 2000-01-01 | Warner Lambert Co | Estereoisomeros individuales de 7-(3-(aminoalquil)-1-pirrolidinil)-quinolonas y de naftiridonas utilizados como agentes antibacterianos. |
| US5221676A (en) * | 1992-02-06 | 1993-06-22 | Warner-Lambert Company | 7-substituted quinolones and naphthyridones as antibacterial agents |
| FR2687146B1 (fr) * | 1992-02-12 | 1994-04-01 | Adir Cie | Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| CN1123544A (zh) * | 1993-05-06 | 1996-05-29 | 厄普约翰公司 | 旋光的3-(1-(烷氨基))烷基吡咯烷 |
| US6140510A (en) * | 1993-05-06 | 2000-10-31 | Pharmacia & Upjohn Company | Optically active 3-(1-(carbamoyl))alkyl-2-oxo-pyrrolidines and optically active 3-(1-(alkylamido))alkyl-2-oxo-pyrrolidines |
| US5347017A (en) * | 1993-07-07 | 1994-09-13 | Warner-Lambert Company | Process for chiral 3-(1-amino-1,1-bisalkylmethyl)-1-substituted-pyrrolidines |
| AU7449398A (en) * | 1997-05-21 | 1998-12-11 | Daiichi Pharmaceutical Co., Ltd. | Cis-disubstituted aminocycloalkyl-pyrrolidine derivatives |
| CN1173971C (zh) * | 1998-11-24 | 2004-11-03 | 第一制药株式会社 | 环烷基取代的氨甲基吡咯烷衍生物 |
| AU2940300A (en) | 1999-03-10 | 2000-09-28 | Daiichi Pharmaceutical Co., Ltd. | Aminomethylpyrrolidine derivatives having aromatic substituents |
| TWI530510B (zh) | 2012-11-01 | 2016-04-21 | 旭化成化學股份有限公司 | 聚異氰酸酯組成物及異氰酸酯聚合物組成物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
| IL79189A (en) * | 1985-06-26 | 1990-07-12 | Daiichi Seiyaku Co | Quinoline and/or naphthyridine-4-oxo-3-carboxylic acid derivatives,process for their preparation and pharmaceutical compositions comprising them |
| JPH0723369B2 (ja) * | 1986-12-27 | 1995-03-15 | 第一製薬株式会社 | ピリドンカルボン酸誘導体 |
| US4780468A (en) * | 1987-08-07 | 1988-10-25 | Warner-Lambert Company | 8-trifluoromethyl quinolones as antibacterial agents |
| CA2012681A1 (en) * | 1989-03-31 | 1990-09-30 | Masayasu Okuhira | Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same |
-
1991
- 1991-07-15 US US07/730,362 patent/US5157128A/en not_active Expired - Lifetime
- 1991-11-12 AU AU90856/91A patent/AU643107B2/en not_active Ceased
- 1991-11-12 WO PCT/US1991/008422 patent/WO1992009597A1/en not_active Ceased
- 1991-11-12 ES ES92900619T patent/ES2113938T3/es not_active Expired - Lifetime
- 1991-11-12 CA CA002095361A patent/CA2095361C/en not_active Expired - Fee Related
- 1991-11-12 CA CA002362944A patent/CA2362944C/en not_active Expired - Fee Related
- 1991-11-12 DK DK92900619T patent/DK0559752T3/da active
- 1991-11-12 JP JP4501923A patent/JP2582515B2/ja not_active Expired - Fee Related
- 1991-11-12 EP EP92900619A patent/EP0559752B1/en not_active Expired - Lifetime
- 1991-11-12 DE DE69128838T patent/DE69128838T2/de not_active Expired - Fee Related
- 1991-11-12 AT AT92900619T patent/ATE162789T1/de not_active IP Right Cessation
- 1991-11-28 NZ NZ240783A patent/NZ240783A/en not_active IP Right Cessation
- 1991-11-29 IE IE416191A patent/IE61722B1/en not_active IP Right Cessation
- 1991-11-29 PT PT99658A patent/PT99658B/pt not_active IP Right Cessation
-
1992
- 1992-06-29 US US07/906,260 patent/US5278317A/en not_active Expired - Lifetime
-
1993
- 1993-11-26 NZ NZ250300A patent/NZ250300A/xx not_active IP Right Cessation
-
1996
- 1996-07-16 JP JP8185801A patent/JP2817907B2/ja not_active Expired - Fee Related
-
1998
- 1998-03-20 GR GR980400618T patent/GR3026428T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT99658B (pt) | 1999-05-31 |
| CA2362944C (en) | 2003-03-18 |
| WO1992009597A1 (en) | 1992-06-11 |
| NZ240783A (en) | 1994-12-22 |
| JP2817907B2 (ja) | 1998-10-30 |
| US5278317A (en) | 1994-01-11 |
| ES2113938T3 (es) | 1998-05-16 |
| CA2095361A1 (en) | 1992-05-31 |
| NZ250300A (en) | 1995-01-27 |
| DE69128838T2 (de) | 1998-06-25 |
| EP0559752B1 (en) | 1998-01-28 |
| DE69128838D1 (de) | 1998-03-05 |
| ATE162789T1 (de) | 1998-02-15 |
| JP2582515B2 (ja) | 1997-02-19 |
| DK0559752T3 (da) | 1998-09-21 |
| US5157128A (en) | 1992-10-20 |
| IE914161A1 (en) | 1992-06-03 |
| JPH06503089A (ja) | 1994-04-07 |
| CA2362944A1 (en) | 1992-06-11 |
| GR3026428T3 (en) | 1998-06-30 |
| AU9085691A (en) | 1992-06-25 |
| AU643107B2 (en) | 1993-11-04 |
| JPH09100266A (ja) | 1997-04-15 |
| EP0559752A1 (en) | 1993-09-15 |
| IE61722B1 (en) | 1994-11-30 |
| CA2095361C (en) | 2002-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920617 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19990208 |
|
| MM3A | Annulment or lapse |
Effective date: 20060808 |