PT994875E - Derivados de 3-piridil-1-aza-biciclo-alcano para a prevencao e tratamento de desordens do snc - Google Patents
Derivados de 3-piridil-1-aza-biciclo-alcano para a prevencao e tratamento de desordens do sncInfo
- Publication number
- PT994875E PT994875E PT98918598T PT98918598T PT994875E PT 994875 E PT994875 E PT 994875E PT 98918598 T PT98918598 T PT 98918598T PT 98918598 T PT98918598 T PT 98918598T PT 994875 E PT994875 E PT 994875E
- Authority
- PT
- Portugal
- Prior art keywords
- aza
- pyridyl
- bicyclo
- alcano
- bicycle
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/885,397 US6525065B1 (en) | 1997-06-30 | 1997-06-30 | Pharmaceutical compositions and methods for effecting dopamine release |
US08/885,768 US6624173B1 (en) | 1997-06-30 | 1997-06-30 | Pharmaceutical compositions for treating and/or preventing CNS disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
PT994875E true PT994875E (pt) | 2004-06-30 |
Family
ID=27128761
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98918598T PT994875E (pt) | 1997-06-30 | 1998-04-22 | Derivados de 3-piridil-1-aza-biciclo-alcano para a prevencao e tratamento de desordens do snc |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0994875B1 (pt) |
JP (1) | JP2002511090A (pt) |
AT (1) | ATE261443T1 (pt) |
AU (1) | AU7149798A (pt) |
CA (1) | CA2294990C (pt) |
DE (1) | DE69822300T2 (pt) |
DK (1) | DK0994875T3 (pt) |
ES (1) | ES2214707T3 (pt) |
PT (1) | PT994875E (pt) |
WO (1) | WO1999000385A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6432975B1 (en) | 1998-12-11 | 2002-08-13 | Targacept, Inc. | Pharmaceutical compositions and methods for use |
US6953855B2 (en) | 1998-12-11 | 2005-10-11 | Targacept, Inc. | 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
FR2791678B1 (fr) * | 1999-03-30 | 2001-05-04 | Synthelabo | Derives de 1,4-diazabicyclo [3.2.2] nonane-4-carboxylates et -carboxamides, leur preparation et leur application en therapeutique |
AU780492B2 (en) * | 1999-11-01 | 2005-03-24 | Targacept, Inc. | Aryl olefinic azacyclic, and aryl acetylenic azacyclic compounds, pharmaceutical compositions containing them and their use as inhibitors of nicotinic cholinergic receptors |
US6890935B2 (en) | 1999-11-01 | 2005-05-10 | Targacept, Inc. | Pharmaceutical compositions and methods for use |
WO2002015906A1 (en) * | 2000-08-21 | 2002-02-28 | Georgetown University | 2-3-disubstituted quinuclidines as modulators of monoamine transporters and therapeutic and diagnostic methods based thereon |
CA2423050A1 (en) | 2000-09-20 | 2002-03-28 | Ortho-Mcneil Pharmaceutical, Inc. | Pyrazine derivatives as modulators of tyrosine kinases |
GB0202873D0 (en) * | 2002-02-07 | 2002-03-27 | Novartis Ag | Organic compounds |
JP4923630B2 (ja) * | 2006-03-02 | 2012-04-25 | 宇部興産株式会社 | 4−置換テトラヒドロピランの製造方法 |
TW201031664A (en) | 2009-01-26 | 2010-09-01 | Targacept Inc | Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide |
JP5413441B2 (ja) * | 2011-12-09 | 2014-02-12 | 宇部興産株式会社 | 4−置換テトラヒドロピランの製造方法 |
CN104311514B (zh) * | 2014-10-14 | 2016-06-22 | 安徽扬子化工有限公司 | 3-羟甲基四氢呋喃酯的合成方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2022886A1 (en) * | 1989-08-08 | 1991-02-09 | Raymond Baker | Substituted pyridines, their preparation, formulations and use in dementia |
US5242935A (en) * | 1992-03-06 | 1993-09-07 | R. J. Reynolds Tobacco Company | Method for treatment of neurodegenerative diseases |
AU7474794A (en) * | 1993-07-22 | 1995-02-20 | E.I. Du Pont De Nemours And Company | Arthropodicidal azacyclic heterocycles |
US5510355A (en) * | 1994-09-06 | 1996-04-23 | Bencherif; Merouane | Depolarizing skeletal muscle relaxants |
AU5383196A (en) * | 1995-05-17 | 1996-11-29 | R.J. Reynolds Tobacco Company | Pharmaceutical compositions for prevention and treatment of central nervous system disorders |
-
1998
- 1998-04-22 DE DE69822300T patent/DE69822300T2/de not_active Expired - Fee Related
- 1998-04-22 DK DK98918598T patent/DK0994875T3/da active
- 1998-04-22 EP EP98918598A patent/EP0994875B1/en not_active Expired - Lifetime
- 1998-04-22 PT PT98918598T patent/PT994875E/pt unknown
- 1998-04-22 WO PCT/US1998/008145 patent/WO1999000385A1/en active IP Right Grant
- 1998-04-22 ES ES98918598T patent/ES2214707T3/es not_active Expired - Lifetime
- 1998-04-22 JP JP50551699A patent/JP2002511090A/ja not_active Ceased
- 1998-04-22 CA CA002294990A patent/CA2294990C/en not_active Expired - Fee Related
- 1998-04-22 AT AT98918598T patent/ATE261443T1/de not_active IP Right Cessation
- 1998-04-22 AU AU71497/98A patent/AU7149798A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DK0994875T3 (da) | 2004-06-21 |
ES2214707T3 (es) | 2004-09-16 |
AU7149798A (en) | 1999-01-19 |
EP0994875B1 (en) | 2004-03-10 |
WO1999000385A1 (en) | 1999-01-07 |
EP0994875A1 (en) | 2000-04-26 |
CA2294990C (en) | 2007-03-06 |
DE69822300T2 (de) | 2005-03-10 |
ATE261443T1 (de) | 2004-03-15 |
DE69822300D1 (de) | 2004-04-15 |
CA2294990A1 (en) | 1999-01-07 |
JP2002511090A (ja) | 2002-04-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2004108668A3 (en) | Alpha-7 neuronal nicotinic receptor ligands: compositions and methods of use | |
Maelicke et al. | Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease | |
SI1678172T1 (sl) | AzabicikliŽŤne spojine za lajšanje boleŽŤine in zdravljenje motenj centralnega ĹľivŽŤnega sistema | |
PT994875E (pt) | Derivados de 3-piridil-1-aza-biciclo-alcano para a prevencao e tratamento de desordens do snc | |
EP1219622A3 (en) | Pharmaceutical compositions for CNS and other disorders | |
MXPA02001306A (es) | Composiciones farmaceuticas para el tratamiento de enfermedades del sistema nervioso central y otras enfermedades. | |
EP0348360A3 (en) | Pharmacological use of uridine in the treatment of nervous disorders | |
CY1983A (en) | Central Cholecystokinin antagonists for treatment of psychiatric disorders | |
MY130145A (en) | Quinuclidine derivative for treatment of inflammatory and gastrointestinal disorders. | |
PH31335A (en) | Naphthalamides as central nervous system agent. | |
NO20041166L (no) | Anvendelse av optisk rent (+) norcisaprid sammen med et annet terapeutisk middel for fremstilling av et medikament | |
IL113436A0 (en) | Neurotransmitter release enhancers | |
GR3019782T3 (en) | Substituted tetrahydropyridines and hydroxypiperidines as central nervous system agents | |
DE69224448D1 (de) | Imidazol-Verbindungen, Verfahren zu ihrer Herstellung und ihre Anwendung | |
AU4038000A (en) | 4-substituted quinoline derivatives as gaba receptor ligands | |
GB9212308D0 (en) | Therapeutic compositions | |
HU9502848D0 (en) | Imidazoloquinoxalinone derivatives as eaa antagonists | |
Beale et al. | ECT for OCD. | |
NZ515613A (en) | Chromeno[4,3,2-de]isoquinolines as potent dopamine receptor ligands | |
AU2002243310A1 (en) | Isoindolyl and isoquinolinyl aroyl pyrrole compounds for the treatment of central nervous system disorders |