PT991415E - Formas de dosagem solidas de ribavirina administraveis por via oral e processo para a sua producao - Google Patents

Formas de dosagem solidas de ribavirina administraveis por via oral e processo para a sua producao

Info

Publication number
PT991415E
PT991415E PT98965983T PT98965983T PT991415E PT 991415 E PT991415 E PT 991415E PT 98965983 T PT98965983 T PT 98965983T PT 98965983 T PT98965983 T PT 98965983T PT 991415 E PT991415 E PT 991415E
Authority
PT
Portugal
Prior art keywords
oral
production
dosage forms
ribavirin dosage
solid
Prior art date
Application number
PT98965983T
Other languages
English (en)
Portuguese (pt)
Inventor
Imtiaz A Chaudry
Stephen M Liebowitz
Elliot Isaac Stupak
Winston A Vadino
Frank E Bowen
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27130673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT991415(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/997,172 external-priority patent/US5914128A/en
Priority claimed from US08/997,169 external-priority patent/US5916594A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of PT991415E publication Critical patent/PT991415E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT98965983T 1997-12-22 1998-12-21 Formas de dosagem solidas de ribavirina administraveis por via oral e processo para a sua producao PT991415E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/997,172 US5914128A (en) 1997-12-22 1997-12-22 Orally administrable solid dosage form
US08/997,169 US5916594A (en) 1997-12-22 1997-12-22 Process of making solid ribavirin dosage forms

Publications (1)

Publication Number Publication Date
PT991415E true PT991415E (pt) 2003-06-30

Family

ID=27130673

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98965983T PT991415E (pt) 1997-12-22 1998-12-21 Formas de dosagem solidas de ribavirina administraveis por via oral e processo para a sua producao

Country Status (26)

Country Link
US (3) US6337090B1 (https=)
EP (2) EP1321147A1 (https=)
JP (2) JP2001526234A (https=)
KR (1) KR100575389B1 (https=)
CN (1) CN1155388C (https=)
AR (1) AR008977A1 (https=)
AT (1) ATE234103T1 (https=)
AU (1) AU762826B2 (https=)
BR (1) BR9814367A (https=)
CA (4) CA2365412C (https=)
CO (1) CO4970774A1 (https=)
DE (1) DE69812094T2 (https=)
DK (1) DK0991415T3 (https=)
ES (1) ES2191987T3 (https=)
HU (1) HUP0100433A3 (https=)
IL (1) IL136549A (https=)
MY (1) MY119656A (https=)
NO (1) NO20003234L (https=)
NZ (1) NZ504994A (https=)
PE (1) PE20000066A1 (https=)
PL (1) PL190267B1 (https=)
PT (1) PT991415E (https=)
SK (1) SK284520B6 (https=)
TW (1) TW575436B (https=)
WO (1) WO1999032128A1 (https=)
ZA (1) ZA9811726B (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE234103T1 (de) * 1997-12-22 2003-03-15 Schering Corp Feste, oral verabreichbare ribavirin dosisformen und verfahren zu deren herstellung
US6793934B1 (en) * 1999-12-08 2004-09-21 Shire Laboratories, Inc. Solid oral dosage form
DE60134391D1 (de) * 2000-03-06 2008-07-24 Salient Surgical Technologies Flüssigkeitsabgabesystem und steuerung für elektrochirurgische geräte
US6720000B2 (en) * 2001-03-19 2004-04-13 Three Rivers Pharmaceutical, Llc Process for producing wet ribavirin pellets
KR20030020137A (ko) * 2001-09-03 2003-03-08 진양제약주식회사 리바비린 건조시럽제
EP1443911A1 (en) * 2001-11-02 2004-08-11 Geneva Pharmaceuticals, Inc. Process for preparing quick dissolving, high loading ribavirin compositions
DE10227148A1 (de) * 2002-06-18 2004-01-08 Biopartners Gmbh Verwendung von Ribavirin zur Herstellung einer pharmazeutischen Zusammensetzung gegen Bunyaviridae
US7538094B2 (en) * 2002-09-19 2009-05-26 Three Rivers Pharmacueticals, Llc Composition containing ribavirin and use thereof
US20040142903A1 (en) * 2003-01-16 2004-07-22 Par Pharmaceutical Inc. Bioavailable fenofibrate compositions, methods for treating hyperlipidemia and hypercholesterolemia and processes for the preparation of such compositions
RU2005133093A (ru) * 2003-03-28 2006-07-27 Фармассет, Инк. (Us) Соединения для лечения флавивирусных инфекций
TR200701424T1 (tr) * 2004-09-09 2007-04-24 Bayer Healthcare Ag Suda çözünebilen katı dozaj formunda farmasötik bileşim.
US7723310B2 (en) * 2004-10-18 2010-05-25 Three Rivers Pharmaceuticals, Llc Large dose ribavirin formulations
JP5694643B2 (ja) * 2005-08-05 2015-04-01 スリーエム イノベイティブ プロパティズ カンパニー 改善された流動性を示す組成物
US20080131398A1 (en) * 2006-08-21 2008-06-05 United Therapeutics Corporation Combination therapy for treatment of viral infections
US9072664B2 (en) * 2008-05-22 2015-07-07 3M Innovative Properties Company Process for manufacturing flowable powder drug compositions
US9956170B2 (en) * 2008-06-26 2018-05-01 3M Innovative Properties Company Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof
EP2309984B1 (en) * 2008-07-02 2018-04-11 3M Innovative Properties Company Method of making a dry powder pharmaceutical composition
EP2295037A1 (en) 2009-09-11 2011-03-16 Ratiopharm GmbH Pharmaceutical formulation containing Ribavirin
US10363453B2 (en) 2011-02-07 2019-07-30 New Balance Athletics, Inc. Systems and methods for monitoring athletic and physiological performance
CA2752008A1 (en) 2011-09-13 2013-03-13 Universite De Montreal Combination therapy using ribavirin as elf4e inhibitor
CN106389363A (zh) * 2016-10-18 2017-02-15 广东肇庆星湖生物科技股份有限公司 一种利巴韦林口服固体制剂及其制备方法

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1228029C2 (de) * 1964-05-09 1973-05-17 Merck Ag E Verfahren zur Herstellung von Tabletten durch Pressen von Pulvergemischen ohne vorhergehende Granulation
US3490742A (en) * 1966-01-14 1970-01-20 Staley Mfg Co A E Compressed tablets
US3622677A (en) * 1969-07-07 1971-11-23 Staley Mfg Co A E Compressed tablets containing compacted starch as binder-disintegrant ingredient
US4211771A (en) * 1971-06-01 1980-07-08 Robins Ronald K Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
DE2735600A1 (de) * 1977-08-06 1979-02-15 Dynamit Nobel Ag Verfahren zur herstellung von phthalid
JPS57146593A (en) * 1981-03-09 1982-09-10 Ajinomoto Co Inc Preparation of ribofuranosyltriazole derivative
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
US4681765A (en) * 1984-09-13 1987-07-21 American Home Products Corporation Rapid releasing triamterene containing gelatin capsule dosage forms for once daily antihypertensive use
US5077279A (en) * 1986-05-01 1991-12-31 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine anti-viral composition
US5084445A (en) * 1986-05-01 1992-01-28 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
JPS63216820A (ja) * 1987-03-05 1988-09-09 Chugai Pharmaceut Co Ltd 抗ウイルス剤
GB8800276D0 (en) * 1988-01-07 1988-02-10 Univ Liverpool Medical treatment
US5030447A (en) * 1988-03-31 1991-07-09 E. R. Squibb & Sons, Inc. Pharmaceutical compositions having good stability
US5192788A (en) * 1988-05-23 1993-03-09 Georgia State University Foundation, Inc. Porphyrin antiviral compositions
US5109016A (en) * 1988-05-23 1992-04-28 Georgia State University Foundation, Inc. Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions
US5122517A (en) * 1988-06-10 1992-06-16 Regents Of The University Of Minnesota Antiviral combination comprising nucleoside analogs
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
JP2908844B2 (ja) * 1990-06-29 1999-06-21 ヤマサ醤油株式会社 抗ウイルス剤
EP0625158B1 (en) * 1992-01-06 1999-03-31 The Wellcome Foundation Limited Therapeutic nucleosides of the 2',3'-dideoxy-3'-fluoro-purine series
US5869097A (en) * 1992-11-02 1999-02-09 Alza Corporation Method of therapy comprising an osmotic caplet
US5358721A (en) * 1992-12-04 1994-10-25 Alza Corporation Antiviral therapy
JPH06298665A (ja) * 1993-04-14 1994-10-25 Toray Ind Inc 抗ウイルス剤
US5506248A (en) * 1993-08-02 1996-04-09 Bristol-Myers Squibb Company Pharmaceutical compositions having good dissolution properties
US5492692A (en) * 1993-08-17 1996-02-20 University Of Kentucky Research Foundation Coated products with potent anti-HIV and antimicrobial properties
US5370878A (en) * 1993-09-30 1994-12-06 Hallmark Pharmaceuticals, Inc. Method for preparing a direct compression granulated acetaminophen composition
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
CA2135669A1 (en) * 1994-11-10 1996-05-11 Nils O. Johannesson Ribavirin as hepato (liver) protecting agent
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6106865A (en) * 1995-01-09 2000-08-22 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
WO1996026726A1 (en) * 1995-02-28 1996-09-06 Hoechst Marion Roussel, Inc. Pharmaceutical composition for piperidinoalkanol compounds
US6387365B1 (en) * 1995-05-19 2002-05-14 Schering Corporation Combination therapy for chronic hepatitis C infection
US5733578A (en) * 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US5723589A (en) * 1995-12-21 1998-03-03 Icn Pharmaceuticals Carbohydrate conjugated bio-active compounds
IT1282650B1 (it) * 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
US6172046B1 (en) * 1997-09-21 2001-01-09 Schering Corporation Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection
ATE234103T1 (de) * 1997-12-22 2003-03-15 Schering Corp Feste, oral verabreichbare ribavirin dosisformen und verfahren zu deren herstellung
US5914128A (en) * 1997-12-22 1999-06-22 Schering Corporation Orally administrable solid dosage form
US5916594A (en) * 1997-12-22 1999-06-29 Schering Corporation Process of making solid ribavirin dosage forms

Also Published As

Publication number Publication date
AU762826B2 (en) 2003-07-03
MY119656A (en) 2005-06-30
PE20000066A1 (es) 2000-02-09
CN1155388C (zh) 2004-06-30
SK8942000A3 (en) 2001-04-09
CA2365412A1 (en) 1999-07-01
CA2300452A1 (en) 1999-07-01
CA2365412C (en) 2002-09-17
CO4970774A1 (es) 2000-11-07
DE69812094T2 (de) 2003-12-24
CA2323849C (en) 2002-06-11
EP1321147A1 (en) 2003-06-25
JP2006083189A (ja) 2006-03-30
DE69812094D1 (de) 2003-04-17
BR9814367A (pt) 2000-10-17
IL136549A0 (en) 2001-06-14
CA2287056A1 (en) 1999-07-01
IL136549A (en) 2005-05-17
PL190267B1 (pl) 2005-11-30
AR008977A1 (es) 2000-03-08
HUP0100433A2 (hu) 2001-12-28
KR20010033441A (ko) 2001-04-25
US6051252A (en) 2000-04-18
EP0991415B1 (en) 2003-03-12
US6337090B1 (en) 2002-01-08
NO20003234L (no) 2000-08-21
ES2191987T3 (es) 2003-09-16
CA2300452C (en) 2000-11-28
EP0991415A1 (en) 2000-04-12
ZA9811726B (en) 1999-06-21
SK284520B6 (sk) 2005-05-05
NZ504994A (en) 2002-10-25
CA2323849A1 (en) 1999-07-01
KR100575389B1 (ko) 2006-05-03
JP2001526234A (ja) 2001-12-18
ATE234103T1 (de) 2003-03-15
WO1999032128A1 (en) 1999-07-01
DK0991415T3 (da) 2003-06-16
HK1034674A1 (en) 2001-11-02
AU2199199A (en) 1999-07-12
PL341230A1 (en) 2001-03-26
CA2287056C (en) 2000-08-15
NO20003234D0 (no) 2000-06-21
TW575436B (en) 2004-02-11
US6335032B1 (en) 2002-01-01
CN1283117A (zh) 2001-02-07
HUP0100433A3 (en) 2003-01-28

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