PT983266E - Novas tetrahidroisoquinolino tiofenocarboximidamidas - Google Patents

Novas tetrahidroisoquinolino tiofenocarboximidamidas

Info

Publication number
PT983266E
PT983266E PT98921953T PT98921953T PT983266E PT 983266 E PT983266 E PT 983266E PT 98921953 T PT98921953 T PT 98921953T PT 98921953 T PT98921953 T PT 98921953T PT 983266 E PT983266 E PT 983266E
Authority
PT
Portugal
Prior art keywords
tiofenocarboximidamides
tetrahydroisoquinoline
new
new tetrahydroisoquinoline
tetrahydroisoquinoline tiofenocarboximidamides
Prior art date
Application number
PT98921953T
Other languages
English (en)
Portuguese (pt)
Inventor
James Macdonald
James Matz
William Shakespeare
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PT983266E publication Critical patent/PT983266E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT98921953T 1997-05-05 1998-04-28 Novas tetrahidroisoquinolino tiofenocarboximidamidas PT983266E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9701682A SE9701682D0 (sv) 1997-05-05 1997-05-05 Compounds

Publications (1)

Publication Number Publication Date
PT983266E true PT983266E (pt) 2002-05-31

Family

ID=20406836

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98921953T PT983266E (pt) 1997-05-05 1998-04-28 Novas tetrahidroisoquinolino tiofenocarboximidamidas

Country Status (28)

Country Link
US (1) US6166030A (zh)
EP (1) EP0983266B1 (zh)
JP (1) JP2001523263A (zh)
KR (1) KR20010012227A (zh)
CN (1) CN1255130A (zh)
AR (1) AR012602A1 (zh)
AT (1) ATE210661T1 (zh)
AU (1) AU734394B2 (zh)
BR (1) BR9808725A (zh)
CA (1) CA2287999A1 (zh)
DE (1) DE69802923T2 (zh)
DK (1) DK0983266T3 (zh)
EE (1) EE9900475A (zh)
ES (1) ES2168757T3 (zh)
HU (1) HUP0003766A3 (zh)
ID (1) ID23156A (zh)
IL (1) IL132677A0 (zh)
IS (1) IS5237A (zh)
MX (1) MXPA99009874A (zh)
NO (1) NO995404L (zh)
NZ (1) NZ500676A (zh)
PL (1) PL336854A1 (zh)
PT (1) PT983266E (zh)
SE (1) SE9701682D0 (zh)
SK (1) SK140699A3 (zh)
TR (1) TR199902719T2 (zh)
WO (1) WO1998050380A1 (zh)
ZA (1) ZA983740B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566081B1 (en) 1999-10-06 2003-05-20 The Brigham And Women's Hospital, Inc. Methods of identifying a compound which modulates the non-transcriptional non-map-kinase induced effects of steroid hormones
US6683108B1 (en) * 2000-03-30 2004-01-27 Curis, Inc. Agonists of hedgehog signaling pathways and uses related thereto
US8852937B2 (en) * 2000-03-30 2014-10-07 Curis, Inc. Small organic molecule regulators of cell proliferation
US7115653B2 (en) * 2000-03-30 2006-10-03 Curis, Inc. Small organic molecule regulators of cell proliferation
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
JP5833804B2 (ja) 2005-04-13 2015-12-16 ニューラクソン，インコーポレーテッド Ｎｏｓ阻害活性を有する置換インドール化合物
US8173813B2 (en) * 2007-03-23 2012-05-08 Neuraxon, Inc. Quinolone and tetrahydroquinolone and related compounds having NOS inhibitory activity
KR20100103799A (ko) 2007-11-16 2010-09-28 네우렉슨 인코포레이티드 내장통을 치료하기 위한 인돌 화합물 및 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2169280A1 (en) * 1993-08-12 1995-02-23 Robert James Gentile Amidine derivatives with nitric oxide synthetase activities
EP0723438A1 (en) * 1993-10-04 1996-07-31 The Wellcome Foundation Limited Substituted urea and isothiourea derivatives as no synthase inhibitors
CN1077886C (zh) * 1993-10-21 2002-01-16 G·D·瑟尔公司 用作一氧化一氮合酶抑制剂的脒基衍生物
CA2188680A1 (en) * 1994-05-07 1996-01-25 James Edwin Macdonald Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase
KR970706272A (ko) * 1995-08-10 1997-11-03 클래스 빌헬름슨 치료에 유용한 바이시클릭 아미딘 유도체(Bicyclic Amidine Derivatives Useful in Therapy)

Also Published As

Publication number Publication date
WO1998050380A1 (en) 1998-11-12
AU7460098A (en) 1998-11-27
EP0983266B1 (en) 2001-12-12
SE9701682D0 (sv) 1997-05-05
AR012602A1 (es) 2000-11-08
ZA983740B (en) 1999-02-19
EE9900475A (et) 2000-06-15
MXPA99009874A (es) 2004-09-30
NO995404D0 (no) 1999-11-04
AU734394B2 (en) 2001-06-14
SK140699A3 (en) 2000-06-12
ATE210661T1 (de) 2001-12-15
NZ500676A (en) 2001-05-25
IL132677A0 (en) 2001-03-19
BR9808725A (pt) 2000-07-11
DK0983266T3 (da) 2002-03-11
ID23156A (id) 2000-03-23
EP0983266A1 (en) 2000-03-08
CA2287999A1 (en) 1998-11-12
CN1255130A (zh) 2000-05-31
NO995404L (no) 2000-01-05
US6166030A (en) 2000-12-26
HUP0003766A2 (en) 2001-03-28
DE69802923T2 (de) 2002-07-04
ES2168757T3 (es) 2002-06-16
TR199902719T2 (xx) 2000-02-21
PL336854A1 (en) 2000-07-17
JP2001523263A (ja) 2001-11-20
DE69802923D1 (de) 2002-01-24
HUP0003766A3 (en) 2001-09-28
KR20010012227A (ko) 2001-02-15
IS5237A (is) 1999-11-01

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