PT934745E - Utilizacao de derivados de androsterona para a inibicao da ligacao do adn de ap-1 e a proliferacao do musculo liso das vias respiratorias - Google Patents

Utilizacao de derivados de androsterona para a inibicao da ligacao do adn de ap-1 e a proliferacao do musculo liso das vias respiratorias

Info

Publication number
PT934745E
PT934745E PT99200310T PT99200310T PT934745E PT 934745 E PT934745 E PT 934745E PT 99200310 T PT99200310 T PT 99200310T PT 99200310 T PT99200310 T PT 99200310T PT 934745 E PT934745 E PT 934745E
Authority
PT
Portugal
Prior art keywords
androstan
bromo
fluoro
beta
alpha
Prior art date
Application number
PT99200310T
Other languages
English (en)
Inventor
Thomas Preston Kennedy
Original Assignee
Charlotte Mecklenburg Hosp Aut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charlotte Mecklenburg Hosp Aut filed Critical Charlotte Mecklenburg Hosp Aut
Publication of PT934745E publication Critical patent/PT934745E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT99200310T 1998-02-04 1999-02-03 Utilizacao de derivados de androsterona para a inibicao da ligacao do adn de ap-1 e a proliferacao do musculo liso das vias respiratorias PT934745E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1878298A 1998-02-04 1998-02-04

Publications (1)

Publication Number Publication Date
PT934745E true PT934745E (pt) 2004-09-30

Family

ID=21789760

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99200310T PT934745E (pt) 1998-02-04 1999-02-03 Utilizacao de derivados de androsterona para a inibicao da ligacao do adn de ap-1 e a proliferacao do musculo liso das vias respiratorias

Country Status (8)

Country Link
EP (1) EP0934745B1 (pt)
JP (2) JP3895490B2 (pt)
AT (1) ATE265214T1 (pt)
AU (1) AU763307B2 (pt)
CA (1) CA2260584C (pt)
DE (1) DE69916672T2 (pt)
ES (1) ES2221297T3 (pt)
PT (1) PT934745E (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
WO2003105775A2 (en) * 2002-06-17 2003-12-24 Epigenesis Pharmaceuticals, Inc. Dihydrate dehydroepiandrosterone and methods of treating asthma or chronic obstructive pulmonary disease using compostions thereof
EP2298316A1 (en) * 2002-08-28 2011-03-23 Harbor BioSciences, Inc. Therapeutic treatment methods
US20050026883A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a PDE-4 inhibitor for treatment of asthma or chronic obstructive pulmonary disease
US20110262502A1 (en) * 2010-02-08 2011-10-27 Prairie Pharmaceuticals LLC Pulmonary delivery of 17-hydroxyprogesterone caproate (17-hpc)
EP3689364A1 (en) * 2010-02-08 2020-08-05 Shenzhen Evergreen Therapeutics Co., Ltd. Methods for the use of progestogen as a glucocorticoid sensitizer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8306370D0 (sv) * 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
US4529548A (en) * 1984-05-07 1985-07-16 E. R. Squibb & Sons, Inc. 17β-(substituted thio)androstenes
HUT72968A (en) * 1993-03-09 1996-06-28 Univ Utah Res Found Process for producing pharmaceutical composition which is applicable for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
EP0758230B1 (en) * 1994-04-05 2003-06-11 Celltech Therapeutics Limited Use of steroid sulphatase inhibitors
US5660835A (en) * 1995-02-24 1997-08-26 East Carolina University Method of treating adenosine depletion
US5859000A (en) * 1995-06-07 1999-01-12 University Of Utah Research Foundation Method for reducing mast cell mediated allergic reactions

Also Published As

Publication number Publication date
JP3895490B2 (ja) 2007-03-22
AU763307B2 (en) 2003-07-17
DE69916672D1 (de) 2004-06-03
EP0934745A1 (en) 1999-08-11
ES2221297T3 (es) 2004-12-16
DE69916672T2 (de) 2005-04-07
CA2260584A1 (en) 1999-08-04
AU1469399A (en) 1999-04-01
JP2006342180A (ja) 2006-12-21
EP0934745B1 (en) 2004-04-28
ATE265214T1 (de) 2004-05-15
JP2000016939A (ja) 2000-01-18
CA2260584C (en) 2007-07-31

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