PT93071A - Processo para a preparacao de novas 4`-epi-4`-amino-antraciclinas e de composicoes farmaceuticas que as contem - Google Patents
Processo para a preparacao de novas 4`-epi-4`-amino-antraciclinas e de composicoes farmaceuticas que as contemInfo
- Publication number
- PT93071A PT93071A PT93071A PT9307190A PT93071A PT 93071 A PT93071 A PT 93071A PT 93071 A PT93071 A PT 93071A PT 9307190 A PT9307190 A PT 9307190A PT 93071 A PT93071 A PT 93071A
- Authority
- PT
- Portugal
- Prior art keywords
- amino
- anthracyclines
- epi
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 229940045799 anthracyclines and related substance Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- -1 HYDROXY group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- 150000002338 glycosides Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyridine Compounds (AREA)
- Indicating Measured Values (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898902709A GB8902709D0 (en) | 1989-02-07 | 1989-02-07 | New 4'-epi-4'-amino anthracyclines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT93071A true PT93071A (pt) | 1990-08-31 |
| PT93071B PT93071B (pt) | 1996-01-31 |
Family
ID=10651266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT93071A PT93071B (pt) | 1989-02-07 | 1990-02-06 | Processo para a preparacao de novas 4`-epi-4`-amino-antraciclinas e de composicoes farmaceuticas que as contem |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0381989B1 (pt) |
| JP (1) | JP3000562B2 (pt) |
| KR (1) | KR920701227A (pt) |
| AT (1) | ATE72445T1 (pt) |
| AU (1) | AU628478B2 (pt) |
| CA (1) | CA2046645A1 (pt) |
| DE (1) | DE69000019D1 (pt) |
| DK (1) | DK0381989T3 (pt) |
| ES (1) | ES2041050T3 (pt) |
| FI (1) | FI96605C (pt) |
| GB (1) | GB8902709D0 (pt) |
| GR (1) | GR3003873T3 (pt) |
| HU (1) | HU206700B (pt) |
| IE (1) | IE62307B1 (pt) |
| IL (1) | IL93258A (pt) |
| MY (1) | MY105541A (pt) |
| NZ (1) | NZ232305A (pt) |
| PT (1) | PT93071B (pt) |
| RU (1) | RU2073681C1 (pt) |
| WO (1) | WO1990009392A1 (pt) |
| ZA (1) | ZA90835B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1241927B (it) * | 1990-05-14 | 1994-02-01 | Menarini Farma Ind | 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono |
| CN1089071C (zh) * | 1999-10-11 | 2002-08-14 | 葛水生 | 铁路列车卫星电视系统 |
| IT1317106B1 (it) * | 2000-11-16 | 2003-05-26 | Menarini Ricerche Spa | Processo per la sintesi di antracicline otticamente attive. |
| JP5105403B2 (ja) | 2006-12-06 | 2012-12-26 | 日本サーモスタット株式会社 | 感温インジケータ |
| KR101762047B1 (ko) * | 2012-11-05 | 2017-07-27 | 화이자 인코포레이티드 | 스플라이세오스타틴 유사체 |
| DK2991993T3 (en) * | 2013-04-29 | 2018-07-30 | Nerviano Medical Sciences Srl | NEW MORPHOLINYLANTHRACYCLINE DERIVATIVES |
| EP3215513B1 (en) | 2014-11-05 | 2019-05-08 | Nerviano Medical Sciences S.r.l. | Functionalized morpholinyl anthracycline derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57106695A (en) * | 1980-11-01 | 1982-07-02 | Erba Carlo Spa | Anthracycline g lycoside compound |
| GB2091243B (en) * | 1981-01-21 | 1984-06-20 | Erba Farmitalia | Anthracycline glycosides |
| GB8803076D0 (en) * | 1988-02-10 | 1988-03-09 | Erba Carlo Spa | 3'-deamino-4'-deoxy-4'-amino anthracyclines |
-
1989
- 1989-02-07 GB GB898902709A patent/GB8902709D0/en active Pending
-
1990
- 1990-01-23 DE DE9090101309T patent/DE69000019D1/de not_active Expired - Lifetime
- 1990-01-23 ES ES199090101309T patent/ES2041050T3/es not_active Expired - Lifetime
- 1990-01-23 DK DK90101309.4T patent/DK0381989T3/da active
- 1990-01-23 AT AT90101309T patent/ATE72445T1/de not_active IP Right Cessation
- 1990-01-23 EP EP90101309A patent/EP0381989B1/en not_active Expired - Lifetime
- 1990-01-31 NZ NZ232305A patent/NZ232305A/xx unknown
- 1990-02-02 RU SU905001277A patent/RU2073681C1/ru active
- 1990-02-02 IL IL9325890A patent/IL93258A/en not_active IP Right Cessation
- 1990-02-02 JP JP2502349A patent/JP3000562B2/ja not_active Expired - Fee Related
- 1990-02-02 MY MYPI90000164A patent/MY105541A/en unknown
- 1990-02-02 AU AU49510/90A patent/AU628478B2/en not_active Ceased
- 1990-02-02 KR KR1019910700835A patent/KR920701227A/ko not_active Ceased
- 1990-02-02 HU HU901678A patent/HU206700B/hu not_active IP Right Cessation
- 1990-02-02 CA CA002046645A patent/CA2046645A1/en not_active Abandoned
- 1990-02-02 WO PCT/EP1990/000183 patent/WO1990009392A1/en not_active Ceased
- 1990-02-05 ZA ZA90835A patent/ZA90835B/xx unknown
- 1990-02-05 IE IE40390A patent/IE62307B1/en not_active IP Right Cessation
- 1990-02-06 PT PT93071A patent/PT93071B/pt active IP Right Grant
-
1991
- 1991-08-02 FI FI913699A patent/FI96605C/fi active
-
1992
- 1992-02-21 GR GR920400293T patent/GR3003873T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0381989A1 (en) | 1990-08-16 |
| IE62307B1 (en) | 1995-01-25 |
| JPH04503210A (ja) | 1992-06-11 |
| WO1990009392A1 (en) | 1990-08-23 |
| AU4951090A (en) | 1990-09-05 |
| RU2073681C1 (ru) | 1997-02-20 |
| FI913699A0 (fi) | 1991-08-02 |
| GB8902709D0 (en) | 1989-03-30 |
| MY105541A (en) | 1994-10-31 |
| KR920701227A (ko) | 1992-08-11 |
| DK0381989T3 (da) | 1992-03-23 |
| HU206700B (en) | 1992-12-28 |
| IE900403L (en) | 1990-08-07 |
| PT93071B (pt) | 1996-01-31 |
| AU628478B2 (en) | 1992-09-17 |
| HU901678D0 (en) | 1991-11-28 |
| IL93258A0 (en) | 1990-11-29 |
| FI96605B (fi) | 1996-04-15 |
| HUT58065A (en) | 1992-01-28 |
| GR3003873T3 (pt) | 1993-03-16 |
| FI96605C (fi) | 1996-07-25 |
| ATE72445T1 (de) | 1992-02-15 |
| EP0381989B1 (en) | 1992-02-05 |
| JP3000562B2 (ja) | 2000-01-17 |
| ES2041050T3 (es) | 1993-11-01 |
| CA2046645A1 (en) | 1990-08-08 |
| ZA90835B (en) | 1990-11-28 |
| DE69000019D1 (en) | 1992-03-19 |
| NZ232305A (en) | 1991-11-26 |
| IL93258A (en) | 1994-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19951027 |