PT92271B - Processo para a obtencao de preparacoes efervescentes de ibuprofeno - Google Patents

Processo para a obtencao de preparacoes efervescentes de ibuprofeno Download PDF

Info

Publication number
PT92271B
PT92271B PT92271A PT9227189A PT92271B PT 92271 B PT92271 B PT 92271B PT 92271 A PT92271 A PT 92271A PT 9227189 A PT9227189 A PT 9227189A PT 92271 B PT92271 B PT 92271B
Authority
PT
Portugal
Prior art keywords
ibuprofen
effervescent
weight
obtaining
preparation
Prior art date
Application number
PT92271A
Other languages
English (en)
Portuguese (pt)
Other versions
PT92271A (pt
Inventor
Christian Fritsch
Werner Grawingholt
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6367061&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT92271(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PT92271A publication Critical patent/PT92271A/pt
Publication of PT92271B publication Critical patent/PT92271B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT92271A 1988-11-12 1989-11-10 Processo para a obtencao de preparacoes efervescentes de ibuprofeno PT92271B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3838431A DE3838431A1 (de) 1988-11-12 1988-11-12 Ibuprofen-brausezubereitungen

Publications (2)

Publication Number Publication Date
PT92271A PT92271A (pt) 1990-05-31
PT92271B true PT92271B (pt) 1995-08-09

Family

ID=6367061

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92271A PT92271B (pt) 1988-11-12 1989-11-10 Processo para a obtencao de preparacoes efervescentes de ibuprofeno

Country Status (12)

Country Link
US (1) US5445827A (enExample)
EP (1) EP0369228B1 (enExample)
JP (1) JP2735903B2 (enExample)
AT (1) ATE70438T1 (enExample)
AU (1) AU616066B2 (enExample)
CA (1) CA2002732A1 (enExample)
DE (2) DE3838431A1 (enExample)
ES (1) ES2028430T3 (enExample)
FI (1) FI895342A7 (enExample)
GR (1) GR3003685T3 (enExample)
HU (2) HU202103B (enExample)
PT (1) PT92271B (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3838431A1 (de) * 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
US5922351A (en) * 1991-03-27 1999-07-13 Bayer Corporation Lubricants for use in tabletting
DK0584108T3 (da) 1991-05-13 2000-10-09 Boots Co Plc Farmaceutisk præparat omfattende ibuprofensalt
US5302397A (en) * 1991-11-19 1994-04-12 Amsden Brian G Polymer-based drug delivery system
FR2698788B1 (fr) * 1992-12-09 1995-03-03 Union Pharma Scient Appl Composition pharmaceutique effervescente contenant de l'ibuprofène et son procédé de préparation.
GB9316580D0 (en) * 1993-08-10 1993-09-29 Smithkline Beecham Plc Pharmaceutical composition
ES2133454T3 (es) * 1993-09-07 1999-09-16 Gergely Gerhard Mezcla efervescente con sales alcalinas o lisinatos de principios activos acidos, insolubles o dificilmente solubles.
ES2079327B1 (es) * 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.
GB9426218D0 (en) * 1994-12-23 1995-02-22 Procter & Gamble Processes of preparing pharmaceutical compositions
TW442287B (en) * 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
DE19606151C2 (de) * 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
US20040151768A1 (en) * 1997-07-23 2004-08-05 Chiesi Farmaceutici S.P.A. Pharmaceutical compositions containing an effervescent acid-base couple
IT1293764B1 (it) * 1997-07-23 1999-03-10 Chiesi Farma Spa Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua
US5843477A (en) * 1997-09-30 1998-12-01 Bayer Corporation Lubricants for use in tabletting
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
US20030118645A1 (en) * 1998-04-29 2003-06-26 Pather S. Indiran Pharmaceutical compositions for rectal and vaginal administration
US20030091629A1 (en) 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US6974590B2 (en) 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
GB0113842D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
US20030068356A1 (en) * 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
ITMI20020557A1 (it) * 2002-03-15 2003-09-15 Acraf Uso di un sale dell'acido l-ascorbico per preparare una composizione farmaceutica per uso topico oftalmico capace di migliorare il livello d
WO2005021056A1 (en) * 2003-08-21 2005-03-10 Cns, Inc. Effervescent delivery system
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
NZ548215A (en) * 2003-12-31 2009-08-28 Cima Labs Inc Effervescent oral opiate dosage form
WO2005065317A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral fentanyl dosage form
KR101184138B1 (ko) * 2003-12-31 2012-09-19 시마 랩스 인크. 일반적인 선형 발포성 경구 펜타닐 투약 제형 및 투여 방법
RU2403033C2 (ru) * 2005-03-22 2010-11-10 Лозан Фарма Гмбх Солюбилизированный ибупрофен
EP1800667A1 (en) 2005-12-23 2007-06-27 Losan Pharma GmbH Rapidly solubilizing ibuprofen granulate
EP1905428A1 (de) * 2006-09-26 2008-04-02 Losan Pharma GmbH Ibuprofen-Brausezubereitung mit hoher Lösungsgeschwindigkeit und Verfahren zu deren Herstellung
EP2309988B1 (en) * 2008-07-21 2015-11-25 SI Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
LT2953617T (lt) * 2013-02-06 2020-01-10 Hermes Arzneimittel Gmbh Farmacinės kompozicijos, apimančios mažų dozių vaistus
HUE051900T2 (hu) 2014-06-20 2021-03-29 Hermes Arzneimittel Gmbh Íz-leplezett orális gyógyászati készítmény
WO2017060920A1 (en) * 2015-10-05 2017-04-13 Strides Shasun Limited Pharmaceutical compositions
GB2546513B (en) * 2016-01-20 2020-09-16 Cubic Pharmaceuticals Ltd Process of preparing active pharmaceutical ingredient salts

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
EP0070714B1 (en) * 1981-07-20 1986-05-07 The Upjohn Company Use of ibuprofen or flurbiprofen for the manufacture of a medicament for treating respiratory disorders
US4687662A (en) * 1985-08-30 1987-08-18 Warner-Lambert Company Therapeutic effervescent composition
IE59106B1 (en) * 1985-05-31 1994-01-12 Warner Lambert Co A therapeutic effervescent composition and a method of preparing the same
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
GB8528195D0 (en) * 1985-11-15 1985-12-18 Boots Co Plc Therapeutic compositions
US4684666A (en) * 1986-08-19 1987-08-04 Haas Pharmaceuticals, Inc. Stabilized liquid analgesic compositions
DE3838431A1 (de) * 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen

Also Published As

Publication number Publication date
JP2735903B2 (ja) 1998-04-02
EP0369228A1 (de) 1990-05-23
JPH02178223A (ja) 1990-07-11
FI895342A0 (fi) 1989-11-09
ATE70438T1 (de) 1992-01-15
ES2028430T3 (es) 1992-07-01
GR3003685T3 (enExample) 1993-03-16
DE58900594D1 (de) 1992-01-30
DE3838431A1 (de) 1990-05-17
HUT51892A (en) 1990-06-28
FI895342A7 (fi) 1990-05-13
EP0369228B1 (de) 1991-12-18
US5445827A (en) 1995-08-29
PT92271A (pt) 1990-05-31
HU211692A9 (en) 1995-12-28
AU4441789A (en) 1990-05-17
HU895858D0 (en) 1990-02-28
CA2002732A1 (en) 1990-05-12
AU616066B2 (en) 1991-10-17
HU202103B (en) 1991-02-28

Similar Documents

Publication Publication Date Title
US5445827A (en) Effervescent ibuprofen preparations
CA1320192C (en) Pharmaceutical compositions
KR940002659B1 (ko) 치료제 조성물의 제조방법
HU206265B (en) Process for producing pharmaceutical compositions comprising morphine
ES2240033T3 (es) Comprimido matricial que permite la liberacion prolongada de trimetazidina tras su administracion oral.
ES2391912T3 (es) Formulación en polvo del valganciclovir
JPH0356418A (ja) 冷蔵庫温度で安定なホリニン酸塩水溶液並びにその製造方法
PL205325B1 (pl) Kompozycja farmaceutyczna zawierająca aksetyl cefuroksymu
PT95291B (pt) Processo para a preparacao de composicoes soluveis em agua, nao efervescentes, contendo acido 2-(4-isobutilfenil)-propionico (ibuprofeno) sob a forma de sal
SI21259A (sl) Farmacevtski pripravki z antibiotičnim delovanjem
PT1054672E (pt) Microgrânulos de sulfato de morfina, processo de fabrico e preparações farmacêuticas
KR100351193B1 (ko) 아세틸살리실산메토클로프라미드화합물로구성된활성성분을갖는산제제조용조성물
AU743043B2 (en) Pharmaceutical preparations of cilansetron stabilized against racemization
KR20250134679A (ko) 라니피브라노르 제형
WO2020011753A1 (en) Compositions for therapeutic uses containing 5-htp and carbidopa
CA1183086A (en) Antimicrobial preparation
WO2018069805A2 (en) Method for preparation of liquid oral composition of l-thyroxin
FI89455B (fi) Foerfarande foer framstaellning av en farmaceutisk komposition
US5935603A (en) Water soluble powder form compositions and their applications thereof
GB1575977A (en) Solid choline salicylate compositions
SK97296A3 (en) Oral dosage form with acidic active substances and a process for producing the same
US2998350A (en) Article of manufacture for the treatment of alcoholism
WO2021001806A1 (en) Stable dipyridamole formulations with reduced impurities
HK40062283A (en) Liquid pharmaceutical compositions
IE45201B1 (en) Solid choline salicylate compositions

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19950403

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19961031