PT91538A - Processo para a preparacao de novos derivados peptidicos com accao agonista do neuropeptido y - Google Patents
Processo para a preparacao de novos derivados peptidicos com accao agonista do neuropeptido yInfo
- Publication number
- PT91538A PT91538A PT91538A PT9153889A PT91538A PT 91538 A PT91538 A PT 91538A PT 91538 A PT91538 A PT 91538A PT 9153889 A PT9153889 A PT 9153889A PT 91538 A PT91538 A PT 91538A
- Authority
- PT
- Portugal
- Prior art keywords
- neuropeptido
- preparation
- agonist action
- derivatives
- peptidic derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57545—Neuropeptide Y
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23759188A | 1988-08-26 | 1988-08-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT91538A true PT91538A (pt) | 1990-03-08 |
PT91538B PT91538B (pt) | 1995-05-04 |
Family
ID=22894367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT91538A PT91538B (pt) | 1988-08-26 | 1989-08-24 | Processo para a preparacao de novos derivados peptidicos com accao agonista do neuropeptido y |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0355793B1 (pt) |
JP (1) | JP2791955B2 (pt) |
KR (1) | KR0149160B1 (pt) |
CN (1) | CN1042155A (pt) |
AT (1) | ATE140235T1 (pt) |
AU (1) | AU618118B2 (pt) |
CA (1) | CA1341336C (pt) |
DE (1) | DE68926804T2 (pt) |
DK (1) | DK420789A (pt) |
ES (1) | ES2091757T3 (pt) |
FI (1) | FI894006A (pt) |
HU (1) | HU204852B (pt) |
IL (1) | IL91395A0 (pt) |
NO (1) | NO893430L (pt) |
NZ (1) | NZ230384A (pt) |
PT (1) | PT91538B (pt) |
ZA (1) | ZA896376B (pt) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3419454B2 (ja) * | 1991-11-06 | 2003-06-23 | ガーヴァン インスティチュート オブ メディカル リサーチ | ヒト神経ペプチドy−y1レセプター |
AU662032B2 (en) * | 1991-12-19 | 1995-08-17 | Garvan Institute Of Medical Research | A novel molecule which inhibits neuropeptide tyrosine biological function |
JPH08501055A (ja) * | 1991-12-19 | 1996-02-06 | ガーヴァン インスティチュート オブ メディカル リサーチ | 神経ペプチドチロシンの生物学的機能を抑制する新規な分子 |
GB9213215D0 (en) * | 1992-06-20 | 1992-08-05 | Wellcome Found | Peptides |
JPH11501281A (ja) * | 1993-06-18 | 1999-02-02 | ユニバーシティ オブ シンシナティ | 神経ペプチドyアンタゴニスト及びアゴニスト |
US5516653A (en) * | 1993-12-28 | 1996-05-14 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof |
US5545549A (en) | 1994-02-03 | 1996-08-13 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof |
US5989920A (en) | 1994-12-02 | 1999-11-23 | Synaptic Pharmaceutical Corporation | Methods of modifying feeding behavior compounds useful in such methods and DNA encoding a hypothalmic atypical neuropeptide Y/peptide YY receptor Y5 |
US5602024A (en) | 1994-12-02 | 1997-02-11 | Synaptic Pharmaceutical Corporation | DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof |
AUPN646795A0 (en) | 1995-11-09 | 1995-11-30 | Garvan Institute Of Medical Research | Neuropeptide Y-Y5 receptor |
DE19652033A1 (de) * | 1996-12-13 | 1998-06-18 | Irmgard Dr Med Guertner | Neuropeptid (CGRP) als Modulator zur Zelldifferenzierung und Proliferation |
US6713265B1 (en) | 1997-06-04 | 2004-03-30 | Synaptic Pharmaceutical Corporation | Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) |
EP1620091B1 (en) | 2003-05-05 | 2010-03-31 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
NZ546887A (en) | 2003-11-03 | 2009-04-30 | Probiodrug Ag | Combinations useful for the treatment of neuronal disorders |
JP4996926B2 (ja) | 2004-02-05 | 2012-08-08 | プロビオドルグ エージー | グルタミニルシクラーゼの新規の阻害剤 |
WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
US9126987B2 (en) | 2006-11-30 | 2015-09-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
CA2679446C (en) | 2007-03-01 | 2016-05-17 | Probiodrug Ag | New use of glutaminyl cyclase inhibitors |
DK2142514T3 (da) | 2007-04-18 | 2015-03-23 | Probiodrug Ag | Thioureaderivater som glutaminylcyclase-inhibitorer |
WO2011029920A1 (en) | 2009-09-11 | 2011-03-17 | Probiodrug Ag | Heterocylcic derivatives as inhibitors of glutaminyl cyclase |
JP6026284B2 (ja) | 2010-03-03 | 2016-11-16 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤 |
BR112012022478B1 (pt) | 2010-03-10 | 2021-09-21 | Probiodrug Ag | Inibidores heterocíclicos de glutaminil ciclase (qc, ec 2.3.2.5), seu processo de preparação, e composição farmacêutica |
EP2560953B1 (en) | 2010-04-21 | 2016-01-06 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
EP2686313B1 (en) | 2011-03-16 | 2016-02-03 | Probiodrug AG | Benzimidazole derivatives as inhibitors of glutaminyl cyclase |
EP3461819B1 (en) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
CN111494606B (zh) * | 2020-04-24 | 2021-12-14 | 广州医科大学 | 神经肽y的新应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3811193A1 (de) * | 1988-04-01 | 1989-10-19 | Boehringer Ingelheim Kg | Neue peptide, verfahren zu ihrer herstellung und diese peptide enthaltende pharmazeutische zusammensetzungen |
-
1989
- 1989-08-21 ZA ZA896376A patent/ZA896376B/xx unknown
- 1989-08-22 DE DE68926804T patent/DE68926804T2/de not_active Expired - Lifetime
- 1989-08-22 NZ NZ230384A patent/NZ230384A/en unknown
- 1989-08-22 EP EP89115469A patent/EP0355793B1/en not_active Expired - Lifetime
- 1989-08-22 AT AT89115469T patent/ATE140235T1/de not_active IP Right Cessation
- 1989-08-22 JP JP1214292A patent/JP2791955B2/ja not_active Expired - Lifetime
- 1989-08-22 ES ES89115469T patent/ES2091757T3/es not_active Expired - Lifetime
- 1989-08-23 CA CA000609198A patent/CA1341336C/en not_active Expired - Lifetime
- 1989-08-23 IL IL91395A patent/IL91395A0/xx unknown
- 1989-08-24 KR KR1019890012042A patent/KR0149160B1/ko not_active IP Right Cessation
- 1989-08-24 PT PT91538A patent/PT91538B/pt not_active IP Right Cessation
- 1989-08-25 DK DK420789A patent/DK420789A/da not_active Application Discontinuation
- 1989-08-25 CN CN89106524A patent/CN1042155A/zh active Pending
- 1989-08-25 NO NO89893430A patent/NO893430L/no unknown
- 1989-08-25 HU HU894419A patent/HU204852B/hu not_active IP Right Cessation
- 1989-08-25 FI FI894006A patent/FI894006A/fi not_active Application Discontinuation
- 1989-08-28 AU AU40828/89A patent/AU618118B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
NO893430D0 (no) | 1989-08-25 |
EP0355793B1 (en) | 1996-07-10 |
HUT50849A (en) | 1990-03-28 |
JPH02111794A (ja) | 1990-04-24 |
DE68926804T2 (de) | 1996-12-12 |
CN1042155A (zh) | 1990-05-16 |
IL91395A0 (en) | 1990-04-29 |
KR900002799A (ko) | 1990-03-23 |
AU618118B2 (en) | 1991-12-12 |
NZ230384A (en) | 1996-03-26 |
FI894006A0 (fi) | 1989-08-25 |
AU4082889A (en) | 1990-03-01 |
DK420789A (da) | 1990-02-27 |
ES2091757T3 (es) | 1996-11-16 |
EP0355793A3 (en) | 1992-04-22 |
DE68926804D1 (de) | 1996-08-14 |
HU204852B (en) | 1992-02-28 |
KR0149160B1 (ko) | 1998-10-15 |
ZA896376B (en) | 1990-05-30 |
ATE140235T1 (de) | 1996-07-15 |
EP0355793A2 (en) | 1990-02-28 |
CA1341336C (en) | 2002-01-29 |
NO893430L (no) | 1990-02-27 |
PT91538B (pt) | 1995-05-04 |
DK420789D0 (da) | 1989-08-25 |
FI894006A (fi) | 1990-02-27 |
JP2791955B2 (ja) | 1998-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19941013 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960430 |