DK420789A - Neuropeptid agonister - Google Patents

Neuropeptid agonister

Info

Publication number
DK420789A
DK420789A DK420789A DK420789A DK420789A DK 420789 A DK420789 A DK 420789A DK 420789 A DK420789 A DK 420789A DK 420789 A DK420789 A DK 420789A DK 420789 A DK420789 A DK 420789A
Authority
DK
Denmark
Prior art keywords
agonists
neuropeptid
npy
derivatives
agonism
Prior art date
Application number
DK420789A
Other languages
English (en)
Other versions
DK420789D0 (da
Inventor
John L Krstenansky
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK420789D0 publication Critical patent/DK420789D0/da
Publication of DK420789A publication Critical patent/DK420789A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57545—Neuropeptide Y
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK420789A 1988-08-26 1989-08-25 Neuropeptid agonister DK420789A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23759188A 1988-08-26 1988-08-26

Publications (2)

Publication Number Publication Date
DK420789D0 DK420789D0 (da) 1989-08-25
DK420789A true DK420789A (da) 1990-02-27

Family

ID=22894367

Family Applications (1)

Application Number Title Priority Date Filing Date
DK420789A DK420789A (da) 1988-08-26 1989-08-25 Neuropeptid agonister

Country Status (17)

Country Link
EP (1) EP0355793B1 (da)
JP (1) JP2791955B2 (da)
KR (1) KR0149160B1 (da)
CN (1) CN1042155A (da)
AT (1) ATE140235T1 (da)
AU (1) AU618118B2 (da)
CA (1) CA1341336C (da)
DE (1) DE68926804T2 (da)
DK (1) DK420789A (da)
ES (1) ES2091757T3 (da)
FI (1) FI894006A (da)
HU (1) HU204852B (da)
IL (1) IL91395A0 (da)
NO (1) NO893430L (da)
NZ (1) NZ230384A (da)
PT (1) PT91538B (da)
ZA (1) ZA896376B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3419454B2 (ja) * 1991-11-06 2003-06-23 ガーヴァン インスティチュート オブ メディカル リサーチ ヒト神経ペプチドｙ−ｙ１レセプター
AU662032B2 (en) * 1991-12-19 1995-08-17 Garvan Institute Of Medical Research A novel molecule which inhibits neuropeptide tyrosine biological function
JPH08501055A (ja) * 1991-12-19 1996-02-06 ガーヴァン インスティチュート オブ メディカル リサーチ 神経ペプチドチロシンの生物学的機能を抑制する新規な分子
GB9213215D0 (en) * 1992-06-20 1992-08-05 Wellcome Found Peptides
JPH11501281A (ja) * 1993-06-18 1999-02-02 ユニバーシティ オブ シンシナティ 神経ペプチドｙアンタゴニスト及びアゴニスト
US5516653A (en) * 1993-12-28 1996-05-14 Synaptic Pharmaceutical Corporation DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof
US5545549A (en) 1994-02-03 1996-08-13 Synaptic Pharmaceutical Corporation DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof
US5989920A (en) 1994-12-02 1999-11-23 Synaptic Pharmaceutical Corporation Methods of modifying feeding behavior compounds useful in such methods and DNA encoding a hypothalmic atypical neuropeptide Y/peptide YY receptor Y5
US5602024A (en) 1994-12-02 1997-02-11 Synaptic Pharmaceutical Corporation DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof
AUPN646795A0 (en) 1995-11-09 1995-11-30 Garvan Institute Of Medical Research Neuropeptide Y-Y5 receptor
DE19652033A1 (de) * 1996-12-13 1998-06-18 Irmgard Dr Med Guertner Neuropeptid (CGRP) als Modulator zur Zelldifferenzierung und Proliferation
US6713265B1 (en) 1997-06-04 2004-03-30 Synaptic Pharmaceutical Corporation Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5)
EP1620091B1 (en) 2003-05-05 2010-03-31 Probiodrug AG Inhibitors of glutaminyl cyclase
NZ546887A (en) 2003-11-03 2009-04-30 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
JP4996926B2 (ja) 2004-02-05 2012-08-08 プロビオドルグ エージー グルタミニルシクラーゼの新規の阻害剤
WO2008055945A1 (en) 2006-11-09 2008-05-15 Probiodrug Ag 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases
US9126987B2 (en) 2006-11-30 2015-09-08 Probiodrug Ag Inhibitors of glutaminyl cyclase
CA2679446C (en) 2007-03-01 2016-05-17 Probiodrug Ag New use of glutaminyl cyclase inhibitors
DK2142514T3 (da) 2007-04-18 2015-03-23 Probiodrug Ag Thioureaderivater som glutaminylcyclase-inhibitorer
WO2011029920A1 (en) 2009-09-11 2011-03-17 Probiodrug Ag Heterocylcic derivatives as inhibitors of glutaminyl cyclase
JP6026284B2 (ja) 2010-03-03 2016-11-16 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤
BR112012022478B1 (pt) 2010-03-10 2021-09-21 Probiodrug Ag Inibidores heterocíclicos de glutaminil ciclase (qc, ec 2.3.2.5), seu processo de preparação, e composição farmacêutica
EP2560953B1 (en) 2010-04-21 2016-01-06 Probiodrug AG Inhibitors of glutaminyl cyclase
EP2686313B1 (en) 2011-03-16 2016-02-03 Probiodrug AG Benzimidazole derivatives as inhibitors of glutaminyl cyclase
EP3461819B1 (en) 2017-09-29 2020-05-27 Probiodrug AG Inhibitors of glutaminyl cyclase
CN111494606B (zh) * 2020-04-24 2021-12-14 广州医科大学 神经肽y的新应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3811193A1 (de) * 1988-04-01 1989-10-19 Boehringer Ingelheim Kg Neue peptide, verfahren zu ihrer herstellung und diese peptide enthaltende pharmazeutische zusammensetzungen

Also Published As

Publication number Publication date
NO893430D0 (no) 1989-08-25
EP0355793B1 (en) 1996-07-10
HUT50849A (en) 1990-03-28
JPH02111794A (ja) 1990-04-24
DE68926804T2 (de) 1996-12-12
CN1042155A (zh) 1990-05-16
IL91395A0 (en) 1990-04-29
KR900002799A (ko) 1990-03-23
AU618118B2 (en) 1991-12-12
NZ230384A (en) 1996-03-26
PT91538A (pt) 1990-03-08
FI894006A0 (fi) 1989-08-25
AU4082889A (en) 1990-03-01
ES2091757T3 (es) 1996-11-16
EP0355793A3 (en) 1992-04-22
DE68926804D1 (de) 1996-08-14
HU204852B (en) 1992-02-28
KR0149160B1 (ko) 1998-10-15
ZA896376B (en) 1990-05-30
ATE140235T1 (de) 1996-07-15
EP0355793A2 (en) 1990-02-28
CA1341336C (en) 2002-01-29
NO893430L (no) 1990-02-27
PT91538B (pt) 1995-05-04
DK420789D0 (da) 1989-08-25
FI894006A (fi) 1990-02-27
JP2791955B2 (ja) 1998-08-27

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Legal Events

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