PT89964A - Processo para a purificacao do factor xiii por cromatografia de afinidade - Google Patents

Processo para a purificacao do factor xiii por cromatografia de afinidade

Info

Publication number
PT89964A
PT89964A PT89964A PT8996489A PT89964A PT 89964 A PT89964 A PT 89964A PT 89964 A PT89964 A PT 89964A PT 8996489 A PT8996489 A PT 8996489A PT 89964 A PT89964 A PT 89964A
Authority
PT
Portugal
Prior art keywords
factor xiii
purification
subunit
affinity chromatography
therapeutic composition
Prior art date
Application number
PT89964A
Other languages
English (en)
Other versions
PT89964B (pt
Inventor
Jurgen Romisch
Werner Stuber
Hartmut Loebermann
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of PT89964A publication Critical patent/PT89964A/pt
Publication of PT89964B publication Critical patent/PT89964B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Press Drives And Press Lines (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
PT89964A 1988-03-11 1989-03-09 Processo para a purificacao do factor xiii por cromatografia de afinidade PT89964B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3808048A DE3808048A1 (de) 1988-03-11 1988-03-11 Verfahren zum affinitaetschromatografischen reinigen von faktor xiii

Publications (2)

Publication Number Publication Date
PT89964A true PT89964A (pt) 1989-11-10
PT89964B PT89964B (pt) 1994-05-31

Family

ID=6349424

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89964A PT89964B (pt) 1988-03-11 1989-03-09 Processo para a purificacao do factor xiii por cromatografia de afinidade

Country Status (12)

Country Link
US (1) US5047506A (pt)
EP (1) EP0332985B1 (pt)
JP (1) JP2778086B2 (pt)
KR (1) KR890014731A (pt)
AT (1) ATE82130T1 (pt)
AU (1) AU627450B2 (pt)
DE (2) DE3808048A1 (pt)
DK (1) DK118789A (pt)
FI (1) FI891121A (pt)
GR (1) GR3007030T3 (pt)
PT (1) PT89964B (pt)
YU (1) YU49889A (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612456A (en) * 1988-11-14 1997-03-18 Zymogenetics, Inc. Factor XIII compositions
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
AU674061B2 (en) * 1993-03-30 1996-12-05 Hoechst Japan Limited Factor XIII for treatment of skin wounds
JPH08333277A (ja) * 1995-06-05 1996-12-17 Hoechst Japan Ltd ヒト血液凝固第ｘｉｉｉ因子の安定化された水性液製剤
JP4670150B2 (ja) 1999-04-02 2011-04-13 味の素株式会社 多量体蛋白質に由来するサブユニットペプチドの製造法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2063070C3 (de) * 1970-12-22 1975-07-24 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Arzneimittels mit fibrinstabilisierender Wirkung
DE2917001A1 (de) * 1978-04-28 1979-11-08 Toyo Jozo Kk Neue disulfidverbindungen
JPS5746921A (en) * 1980-09-02 1982-03-17 Green Cross Corp:The Oral preparation of human blood coagulation factor
GB8414354D0 (en) * 1984-06-05 1984-07-11 Biogen Nv Purifying protein
DE3621371A1 (de) * 1986-03-12 1987-09-17 Behringwerke Ag Gentechnische herstellung von faktor xiiia
DE3734923C1 (de) * 1987-10-15 1989-01-26 Biotest Pharma Gmbh Verfahren zur Herstellung einer sterilen Plasmaproteinloesung,die Fibrinogen und den Gerinnungsfaktor XIII enthaelt

Also Published As

Publication number Publication date
FI891121A (fi) 1989-09-12
DE3808048A1 (de) 1989-09-21
EP0332985A3 (en) 1990-05-09
KR890014731A (ko) 1989-10-25
FI891121A0 (fi) 1989-03-09
AU627450B2 (en) 1992-08-27
DK118789D0 (da) 1989-03-10
EP0332985B1 (de) 1992-11-11
GR3007030T3 (pt) 1993-07-30
DE58902637D1 (de) 1992-12-17
YU49889A (en) 1990-06-30
DK118789A (da) 1989-09-12
AU3122489A (en) 1989-09-14
US5047506A (en) 1991-09-10
ATE82130T1 (de) 1992-11-15
PT89964B (pt) 1994-05-31
JPH01279898A (ja) 1989-11-10
EP0332985A2 (de) 1989-09-20
JP2778086B2 (ja) 1998-07-23

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19931112

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19950531