PT87868A - Processo para a preparacao de polopeptideos contendo homociclostatina e ciclostatinauteis como agentes anti-hipertensivos - Google Patents

Processo para a preparacao de polopeptideos contendo homociclostatina e ciclostatinauteis como agentes anti-hipertensivos

Info

Publication number
PT87868A
PT87868A PT87868A PT8786888A PT87868A PT 87868 A PT87868 A PT 87868A PT 87868 A PT87868 A PT 87868A PT 8786888 A PT8786888 A PT 8786888A PT 87868 A PT87868 A PT 87868A
Authority
PT
Portugal
Prior art keywords
polopeptideos
homocyclostatin
cyclostatinatals
preparation
hypertensive agents
Prior art date
Application number
PT87868A
Other languages
English (en)
Other versions
PT87868B (pt
Inventor
Dennis J Hoover
Robert L Rosatii
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT87868A publication Critical patent/PT87868A/pt
Publication of PT87868B publication Critical patent/PT87868B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT87868A 1987-07-01 1988-06-29 Processo para a preparacao de polopeptideos contendo homociclostatina e ciclostatinauteis como agentes anti-hipertensivos PT87868B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6899287A 1987-07-01 1987-07-01

Publications (2)

Publication Number Publication Date
PT87868A true PT87868A (pt) 1989-06-30
PT87868B PT87868B (pt) 1995-03-01

Family

ID=22086011

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87868A PT87868B (pt) 1987-07-01 1988-06-29 Processo para a preparacao de polopeptideos contendo homociclostatina e ciclostatinauteis como agentes anti-hipertensivos

Country Status (10)

Country Link
EP (1) EP0297816B1 (pt)
JP (1) JPH0631313B2 (pt)
AT (1) ATE102214T1 (pt)
CA (1) CA1321676C (pt)
DE (1) DE3888031T2 (pt)
DK (1) DK362288A (pt)
ES (1) ES2061652T3 (pt)
FI (1) FI883135A (pt)
IE (1) IE61842B1 (pt)
PT (1) PT87868B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3902615A1 (de) * 1988-08-27 1990-03-08 Bayer Ag Aminomethyl-peptide, verfahren zur herstellung und ihre verwendung in arzneimitteln
KR900012945A (ko) * 1989-02-16 1990-09-03 가와무라 요시부미 렌닌 억제활성을 갖는 펩타이트, 그 제조방법 및 용도

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0184855A3 (en) * 1984-12-14 1989-05-03 Abbott Laboratories Resin inhibiting compounds
US4729985A (en) * 1985-08-09 1988-03-08 Pfizer Inc. Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues
DE3538749A1 (de) * 1985-10-31 1987-05-07 Merck Patent Gmbh Peptide
EP0314239A3 (en) * 1987-10-28 1990-12-27 Merck & Co. Inc. Tripeptide renin inhibitors with n-terminal ureido or sulfamido groups

Also Published As

Publication number Publication date
ATE102214T1 (de) 1994-03-15
EP0297816A2 (en) 1989-01-04
FI883135A0 (fi) 1988-06-30
DE3888031T2 (de) 1994-06-09
FI883135A (fi) 1989-01-02
DK362288A (da) 1989-02-24
DE3888031D1 (de) 1994-04-07
EP0297816A3 (en) 1990-09-05
JPH0631313B2 (ja) 1994-04-27
IE881991L (en) 1989-01-01
ES2061652T3 (es) 1994-12-16
CA1321676C (en) 1993-08-24
EP0297816B1 (en) 1994-03-02
JPS6426596A (en) 1989-01-27
DK362288D0 (da) 1988-06-30
IE61842B1 (en) 1994-11-30
PT87868B (pt) 1995-03-01

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940818

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19980228